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7618690 |
Polymerizable liquid crystal compound, liquid crystal composition, optical anisotropic material and optical element
A liquid crystal compound represented by the formula
CH 2 ═CR 1 —COO-(L) k -E 1 -E 2 -E 3 -E 4 -R 2
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7569518 |
Pyridazine Compound and Use Thereof
A pyridazine compound represented by formula (1):
has an excellent plant disease controlling effect.
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7538242 |
Optically active PPAR-activating compound intermediate and method for producing same
The present invention provides a production intermediate for compound (A-1) and a method for producing the intermediate at high yield and high optical yield.
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7528271 |
Intermediates, process for their preparation and synthesis of 1,4-benzoquiones
The present invention discloses a new process for the preparation of 1,4-benzoquiones of formula (II)
wherein R 1 , R 2 , R 3 and R 4 are independently selected from the group consisting of...
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7442837 |
Phenethanolamine derivatives for treatment of respiratory diseases
The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their...
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7442418 |
Polymerizable liquid crystal compound, liquid crystal composition, optical anisotropic material and optical element
The present compound represented by formula(I)
CH 2 ═CR 1 —COO—(L) k -E 1 -E 2 -E 3 -(E 4 ) m -(E 5 ) n -R 2 ...
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7396954 |
Intermediates in producing phenoxyacetic acid preventives and method of using the same
The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically...
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7396953 |
Angiogenesis inhibitors and pharmaceutical/cosmetic applications thereof
Novel derivatives of fumagalone have the general formula (I):
and are useful angiogenes is inhibitors; these can be formulated into pharmaceutical compositions suited for human or veterinary...
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7371888 |
α-(Trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl)-trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetic agents
Compounds having a formula:
or a pharmaceutically acceptable salt or prodrug thereof, are provided, and are useful for the treatment of metabolic disorders.
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7358383 |
Polyphenol proteasome inhibitors, synthesis, and methods of use
The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present...
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7282596 |
Method and intermediate for preparing a prostaglandin F-type compound
A method for preparing a prostaglandin F-type compound. Also disclosed is an intermediate of the following formula (II) compound
wherein R′, X and A have the same meaning as given in the...
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7279593 |
Prime ring substituted thyroid receptor antagonists for the treatment of cardiac and metabolic disorders
This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders,...
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7268249 |
Production process of optically pure 2-(4- hydroxyphenoxy)-propionic acid compounds
A process for producing optically pure R-hydroxyphenoxypropanoic acid or a salt or ester thereof by reaction of hydroquinone or a salt thereof with an S-halopropanoic acid or a salt thereof in the...
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7169808 |
Compounds useful for the preparation of medicaments with phosphodiesterase IV inhibitory activity
Formula (I) compounds are described, where the groups are defined in the description, as well as processes for their preparation and their use as medicaments, particularly as selective...
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7153548 |
Compound, retardation plate and method for forming optically anisotropic layer
A retardation plate having a high film strength and having an optical property is provided by using a biaxial liquid crystal compound, in which the direction having a minimum refractive index of...
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7129268 |
Peroxisome proliferator activated receptor-active arylene acetic acid derivatives
Novel compounds of the general formula (I),
wherein Ar, R 1 , R 2 , X 1 , X 2 , Y 1 , Y, and Z are as defined in the specification, the use of these compounds as pharmaceutical compositions,...
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7070712 |
Acetylene polymers and their use as liquid crystals
There is disclosed a liquid crystalline polyacetylene having a repeat structure of the formula
where spa is a spacer group and mes is a mesogenic substituent.
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7015346 |
Short-acting sedative hypnotic agents for anesthesia and sedation
The invention provides a process for preparing a compound useful for inducing or maintaining general anesthesia or sedation in mammals.
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6991747 |
Radical scavenger
A new chromotropic compound, compositions containing such a compound and methods of using such compound, such as in a test method for identifying the presence of free radicals, are disclosed.
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6905739 |
Optically active materials
A compound is of formula (I), in which: A 1 to A 4 , E 1 and E 2 each independently represent hydrogen or an optionally-substituted hydrocarbon group; B 1 and B 2 each independently represent...
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6897333 |
Process for the preparation of fibrates
A process for the preparation of fibrates of formula I
in which R 1 is a halogen atom, a 2,2-dichloro-cyclopropyl group, a (4-chlorophenyul)-hydroxymethyl group, a-4-chlorobenzoyl group or a...
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6869967 |
Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives
Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these...
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6861391 |
Trifluoromethyl-substituted spirocyclic ketoenols
Trifluoromethyl-substituted spirocyclic ketoenols of the formula (I) are provided
wherein
Het represents one of the groups
and G, V, W, X, Y, and Z are as defined in the specification....
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6858650 |
Stable salts of novel derivatives of 3,3-diphenylpropylamines
The present invention concerns highly pure, crystalline, stable compounds of novel derivatives of 3,3-diphenylpropylamines in the form of their salts, a method for the manufacture and highly pure,...
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6831191 |
Photo stable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom
A compound of formula I wherein A is a moiety which provides UV absorbing activity to the compound of formula I that comprises 1 divalent group or 2 monovalent groups, with at least one group...
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6797838 |
Process for preparing homophthalate derivatives
The present invention provides a process for the preparation of homophthlate esters useful in the preparation of homophthalic anhydride reactants.
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6733690 |
Laterally substituted curable liquid crystals
In one embodiment, the invention relates to compounds of the formula (I) wherein G 1 and G 2 independently represent a polymerisable mesogenic residue, X and Sp are as defined herein and M...
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6696585 |
Functionalized nanoparticles
There are disclosed amphoteric nano-sized metal oxide particles functionalized with silyl esters of a phosphonate and composites thereof with an acrylate-based monomer, including liquid crystal...
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6676851 |
Laterally substituted curable liquid crystals
In one embodiment, the invention relates to compounds of the formula (I) wherein G1 and G2 independently represent a polymerizable mesogenic residue, and X, Sp, and Q are as defined herein. The...
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6653499 |
Photoactive propane derivatives and orientation layers
Compounds of formula (I) may be used as alignment layers in liquid crystal devices wherein X 1-5 are idependently selected from H, F, CN, phenylene, C 1-10 alkyl, whereby when X 1 =X 2 , then X...
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6586609 |
Process for esterification in a chromatographic reactor
Process for the esterification of organic acids with alcohols in a reactor of the chromatographic type in which the heterogeneous solid phase is capable of acting both as an esterification catalyst...
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6559335 |
Process for the preparation of 3-aryl-2-hydroxy propanoic acid
The present invention relates to an improved process for the preparation of 3-aryl-2-hydroxy propanoic acid derivatives of the formula (1) useful as an intermediate for the preparation of many...
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6444850 |
Fungicidial compounds having a fluorovinyloxphyenyl moiety and process for the preparation thereof
A fungicidal compound of formula (I) having a fluorovinyloxyphenyl moiety and stereoisomers thereof are useful for protecting crops from fungal diseases: wherein: X is CH or N; Y is O or S; Z is...
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6410765 |
Methods of making functionalized nanoparticles
There are disclosed amphoteric nano-sized metal oxide particles functionalized with silyl esters of a phosphonate and composites thereof with an acrylate-based monomer, including liquid crystal...
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6339082 |
Tricyclic compounds, preparation method and said method intermediates, application as medicines and pharmaceutical compositions containing same
A compound selected from the group consisting of a compound of the formula wherein the substituents are defined as set forth in the specification and its salts with non-toxic pharmaceutically...
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6337306 |
Phenoxyacetic acid derivatives and their use as herbicides
Phenoxyacetic acid derivatives of the formula: wherein R 1 , R 2 , X n and A are as defined herein, and a process for preparing the derivatives. The derivatives are used as herbicides.
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6310237 |
Process for the preparation and uses of derivatives of esters of α-methylene-β-hydroxy acids
A process for the preparation of derivatives of halo-but-2-enoic acids and esters high in 2-ene content, several of which are novel. The esters and their derivatives are useful as promoters for the...
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6303648 |
Methods and compositions for the treatment and prevention of lung disease
Methods and compositions for the treatment of lung disease, such as emphysema and/or bronchopulmonary dysplasia, in a mammal. Also disclosed are methods promoting the formation of alveolar septa...
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6294580 |
Substituted 4-hydroxy-phenylalcanoic acid derivatives with agonist activity to PPAR-gamma
A compound having formula (I), wherein A is selected from the group consisting of: (i) phenyl, wherein said phenyl is optionally substituted by one or more halogen atoms, C 1 -6 alkyl, C 1 -3...
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6258974 |
Metal oxide compositions composites thereof and method
There are disclosed amphoteric nano-sized metal oxide particles functionalized with silyl esters of a phosphonate and composites thereof with an acrylate-based monomer, including liquid crystal...
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6248899 |
Transesterification catalysts fixed to solid support materials
A description is given of a process for the transesterification of carboxylic esters, characterized in that the catalyst used is a tin(IV) compound comprising a radical of the formula ##STR1##...
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6207853 |
Homogeneous asymmetric hydrogenation using phosphine ligands of transition metals
A process for the preparation of an enantiomerically enriched 2-substituted succinic acid derivative of formula 2, which comprises asymmetric hydrogenation of the dehydro precursor of formula 7 or...
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6177154 |
Alkoxybenzene derivative, liquid-crystal composition, and liquid-crystal display element
Disclosed are (a) liquid crystalline compounds which are essential as component of the liquid crystal compositions, are excellent in miscibility with other liquid crystal compositions,...
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6172239 |
Substituted 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors, their preparation and pharamaceutical compositions containing them
The invention relates to compounds of the formula ##STR1## The compounds have agreat affinity for the neurotensin receptors.
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6153787 |
Intermediates for making heterocycles useful as COX-2 inhibitors
The invention encompasses a process for making compounds of Formula I or Ia useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1##
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6136852 |
3,4-disubstituted phenylethanolaminotetralincarboxylic acid derivatives
The present invention relates to 3,4-disubstituted phenylethanolaminotetralincarboxylic acid derivatives represented by the general formula: ##STR1## [wherein Q represents a vinylene group or a...
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6118019 |
3-alkoxypropionic ester derivative
A 3-alkoxypropionic ester derivative, an olefin polymerization solid catalyst component using the same, an olefin polymerization catalyst using the same, and a process for the preparation of a...
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6107517 |
Thyroid hormone analogues and methods for their preparation
Thyroid hormone analogues are disclosed. Methods of using such analogues and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.
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6048895 |
Aromatic C16-C20 substituted tetrahydro prostaglandins useful as FP agonists
The invention provides novel PGF analogs. In particular, the present invention relates to compounds having a structure according to the following formula: ##STR1## wherein R 1 , R 2 , R 3 , R 4 ,...
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6030993 |
2-hydroxypropionic acid derivative and its manufacturing method
This invention relates to a novel 2-hydroxypropionic acid derivative and its manufacturing method. Based on its mechanism to inhibit the CPT I, 2-hydroxypropionic acid derivative of this invention...
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