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7268249 Production process of optically pure 2-(4- hydroxyphenoxy)-propionic acid compounds  
A process for producing optically pure R-hydroxyphenoxypropanoic acid or a salt or ester thereof by reaction of hydroquinone or a salt thereof with an S-halopropanoic acid or a salt thereof in the...
7169808 Compounds useful for the preparation of medicaments with phosphodiesterase IV inhibitory activity  
Formula (I) compounds are described, where the groups are defined in the description, as well as processes for their preparation and their use as medicaments, particularly as selective...
7153548 Compound, retardation plate and method for forming optically anisotropic layer  
A retardation plate having a high film strength and having an optical property is provided by using a biaxial liquid crystal compound, in which the direction having a minimum refractive index of...
7129268 Peroxisome proliferator activated receptor-active arylene acetic acid derivatives  
Novel compounds of the general formula (I), wherein Ar, R1, R2, X1, X2, Y1, Y, and Z are as defined in the specification, the use of these compounds as pharmaceutical compositions, pharmaceutical...
7070712 Acetylene polymers and their use as liquid crystals  
There is disclosed a liquid crystalline polyacetylene having a repeat structure of the formula where spa is a spacer group and mes is a mesogenic substituent.
7015346 Short-acting sedative hypnotic agents for anesthesia and sedation  
The invention provides a process for preparing a compound useful for inducing or maintaining general anesthesia or sedation in mammals.
6991747 Radical scavenger  
A new chromotropic compound, compositions containing such a compound and methods of using such compound, such as in a test method for identifying the presence of free radicals, are disclosed.
6905739 Optically active materials  
A compound is of formula (I), in which: A1 to A4, E1 and E2 each independently represent hydrogen or an optionally-substituted hydrocarbon group; B1 and B2 each independently represent a single...
6897333 Process for the preparation of fibrates  
A process for the preparation of fibrates of formula I in which R1 is a halogen atom, a 2,2-dichloro-cyclopropyl group, a (4-chlorophenyul)-hydroxymethyl group, a-4-chlorobenzoyl group or a...
6869967 Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives  
Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these...
6861391 Trifluoromethyl-substituted spirocyclic ketoenols  
Trifluoromethyl-substituted spirocyclic ketoenols of the formula (I) are provided wherein Het represents one of the groups and G, V, W, X, Y, and Z are as defined in the specification. Also...
6858650 Stable salts of novel derivatives of 3,3-diphenylpropylamines  
The present invention concerns highly pure, crystalline, stable compounds of novel derivatives of 3,3-diphenylpropylamines in the form of their salts, a method for the manufacture and highly pure,...
6831191 Photo stable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom  
A compound of formula I whereinA is a moiety which provides UV absorbing activity to the compound of formula I that comprises 1 divalent group or 2 monovalent groups, with at least one group...
6797838 Process for preparing homophthalate derivatives  
The present invention provides a process for the preparation of homophthlate esters useful in the preparation of homophthalic anhydride reactants.
6733690 Laterally substituted curable liquid crystals  
In one embodiment, the invention relates to compounds of the formula (I) wherein G1 and G2 independently represent a polymerisable mesogenic residue, X and Sp are as defined herein and M...
6696585 Functionalized nanoparticles  
There are disclosed amphoteric nano-sized metal oxide particles functionalized with silyl esters of a phosphonate and composites thereof with an acrylate-based monomer, including liquid crystal...
6676851 Laterally substituted curable liquid crystals  
In one embodiment, the invention relates to compounds of the formula (I) wherein G1 and G2 independently represent a polymerizable mesogenic residue, and X, Sp, and Q are as defined herein. The...
6653499 Photoactive propane derivatives and orientation layers  
Compounds of formula (I) may be used as alignment layers in liquid crystal devices wherein X1-5 are idependently selected from H, F, CN, phenylene, C1-10 alkyl, whereby when X1=X2, then X1,2=H and...
6586609 Process for esterification in a chromatographic reactor  
Process for the esterification of organic acids with alcohols in a reactor of the chromatographic type in which the heterogeneous solid phase is capable of acting both as an esterification...
6559335 Process for the preparation of 3-aryl-2-hydroxy propanoic acid  
The present invention relates to an improved process for the preparation of 3-aryl-2-hydroxy propanoic acid derivatives of the formula (1) useful as an intermediate for the preparation of many...
6444850 Fungicidial compounds having a fluorovinyloxphyenyl moiety and process for the preparation thereof  
A fungicidal compound of formula (I) having a fluorovinyloxyphenyl moiety and stereoisomers thereof are useful for protecting crops from fungal diseases: wherein:X is CH or N;Y is O or S;Z is O or...
6410765 Methods of making functionalized nanoparticles  
There are disclosed amphoteric nano-sized metal oxide particles functionalized with silyl esters of a phosphonate and composites thereof with an acrylate-based monomer, including liquid crystal...
6339082 Tricyclic compounds, preparation method and said method intermediates, application as medicines and pharmaceutical compositions containing same  
A compound selected from the group consisting of a compound of the formula wherein the substituents are defined as set forth in the specification and its salts with non-toxic pharmaceutically...
6337306 Phenoxyacetic acid derivatives and their use as herbicides  
Phenoxyacetic acid derivatives of the formula: wherein R1, R2, Xn and A are as defined herein, and a process for preparing the derivatives. The derivatives are used as herbicides.
6310237 Process for the preparation and uses of derivatives of esters of α-methylene-β-hydroxy acids  
A process for the preparation of derivatives of halo-but-2-enoic acids and esters high in 2-ene content, several of which are novel. The esters and their derivatives are useful as promoters for...
6303648 Methods and compositions for the treatment and prevention of lung disease  
Methods and compositions for the treatment of lung disease, such as emphysema and/or bronchopulmonary dysplasia, in a mammal. Also disclosed are methods promoting the formation of alveolar septa...
6294580 Substituted 4-hydroxy-phenylalcanoic acid derivatives with agonist activity to PPAR-gamma  
A compound having formula (I), wherein A is selected from the group consisting of: (i) phenyl, wherein said phenyl is optionally substituted by one or more halogen atoms, C1-6 alkyl, C1-3 alkoxy,...
6258974 Metal oxide compositions composites thereof and method  
There are disclosed amphoteric nano-sized metal oxide particles functionalized with silyl esters of a phosphonate and composites thereof with an acrylate-based monomer, including liquid crystal...
6248899 Transesterification catalysts fixed to solid support materials  
A description is given of a process for the transesterification of carboxylic esters, characterized in that the catalyst used is a tin(IV) compound comprising a radical of the formula...
6207853 Homogeneous asymmetric hydrogenation using phosphine ligands of transition metals  
A process for the preparation of an enantiomerically enriched 2-substituted succinic acid derivative of formula 2, which comprises asymmetric hydrogenation of the dehydro precursor of formula 7 or...
6177154 Alkoxybenzene derivative, liquid-crystal composition, and liquid-crystal display element  
Disclosed are (a) liquid crystalline compounds which are essential as component of the liquid crystal compositions, are excellent in miscibility with other liquid crystal compositions,...
6172239 Substituted 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors, their preparation and pharamaceutical compositions containing them  
The invention relates to compounds of the formula ##STR1##The compounds have agreat affinity for the neurotensin receptors.
6153787 Intermediates for making heterocycles useful as COX-2 inhibitors  
The invention encompasses a process for making compounds of Formula I or Ia useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1##
6136852 3,4-disubstituted phenylethanolaminotetralincarboxylic acid derivatives  
The present invention relates to 3,4-disubstituted phenylethanolaminotetralincarboxylic acid derivatives represented by the general formula: ##STR1## [wherein Q represents a vinylene group or a...
6118019 3-alkoxypropionic ester derivative  
A 3-alkoxypropionic ester derivative, an olefin polymerization solid catalyst component using the same, an olefin polymerization catalyst using the same, and a process for the preparation of a...
6107517 Thyroid hormone analogues and methods for their preparation  
Thyroid hormone analogues are disclosed. Methods of using such analogues and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.
6048895 Aromatic C16-C20 substituted tetrahydro prostaglandins useful as FP agonists  
The invention provides novel PGF analogs. In particular, the present invention relates to compounds having a structure according to the following formula: ##STR1## wherein R1, R2, R3, R4, X, and Z...
6030993 2-hydroxypropionic acid derivative and its manufacturing method  
This invention relates to a novel 2-hydroxypropionic acid derivative and its manufacturing method. Based on its mechanism to inhibit the CPT I, 2-hydroxypropionic acid derivative of this invention...
5935986 Azolyl oxybenzyl alkoxyacrylic acid esters, process for producing them and their use  
There are described compounds of the general formula I ##STR1## in which the index and the substituents have the following meanings: n is 0, 1, 2, 3 or 4; R is nitro, cyano, halogen, unsubstituted...
5910508 Polycyclic polyenic compounds and pharmaceutical/cosmetic compositions comprised thereof  
Novel pharmaceutically/cosmetically-active polycyclic polyenic compounds have the structural formula (I): ##STR1## and are useful for modulating cellular hormone receptors.
5886209 Preparation of 2-(4-hydroxyphenoxy) propionates  
A multi-stage catalytic process for preparing a 2-(4-hydroxyphenoxy)-propionate, especially methyl 2-(4-hydroxyphenoxy)-propionate, with a purity greater than 99% by esterifying the corresponding...
5883294 Selective thyroid hormone analogs  
Selective thyroid hormone agonists are disclosed that are highly selective for the TRβ subtype with high binding affinity. Methods of using such agonists and pharmaceutical compositions containing...
5877334 Intermediates useful in solid phase synthesis method  
A solid phase synthesis method and intermediates useful in the process are disclosed for the preparation of diamino diol and diamino alcohol inhibitors of HIV protease.
5869735 Process for the preparation of alkyl aryl ethers containing carboxyl groups  
Process for the preparation of alkyl aryl ethers containing carboxyl groups which are suitable for the preparation of colour film couplers, or derivatives thereof, by reaction of aromatic alcohols...
5855629 Alkoxy acetic acid derivatives  
This invention provides alkoxy acetic acid derivatives of general formula I: ##STR1## wherein R is the residue of an amine, an aminoalcohol or a polyol linked to the or each --CHR'--CO-- moiety...
5777151 Esterification of carboxylic acid salts  
Mono- or polycarboxylic acid esters are prepared by reacting a salt of such carboxylic acid with an organic halocompound, e.g., a (cyclo)alkyl, (cyclo)alkenyl, aryl or aralkyl halide, in an...
5773625 Process for the preparation of disubstituted carbonates  
The present invention relates to a process for the preparation of cabonate compounds useful for the preparation of compounds which are human immunodeficiency virus (HIV) protease inhibitors.The...
5755994 Ester derivative, liquid crystal composition and liquid crystal display element  
A novel liquid crystalline compound having a large dielectric anisotropy value, a small change in the threshold voltage depending upon temperatures, and an improved solubility in other liquid...
5734077 Substituted 2,2-dimethyl-omega-phenoxyalkanoic acids and esters  
New substituted 2,2-dimethyl-ω-phenoxyalkanoic acids and esters of formula: ##STR1## wherein: X, A, B, R, R1, R2, R3, R4, R5, R6, R7 and Z are as defined in the specification,The corresponding...
5728864 Liquid crystal compound having ferrielectric phase and liquid crystal composition  
A liquid crystal compound of the formula (1) ##STR1## wherein R is a linear alkyl group having 6 to 12 carbon atoms, both X and Y are hydrogen atoms or one of X and Y is a fluorine atom and the...