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8101095 Antiferroelectric orthoconic liquid crystalline material with long pitch and the method of its preparation  
The racemic and chiral compounds expressed by common formula 1 and formula 2: wherein the lateral substituents X1, X2, X3, X4, X5, X6, X7 and X8 in the benzene rings represent independently...
8043789 Photosensitive compound and photoresist composition including the same  
A photosensitive compound whose size is smaller than conventional polymer for photoresist, and which has well-defined (uniform) structure, and a photoresist composition including the same are...
8003698 Site-specific inhibitors of histone methyltransferase (HMTASE) and process of preparation thereof  
The present invention relates to compounds of structural formula I as site-specific inhibitors of histone methyltransferase, where R1 and R1 is —OCH3 or —OH, R2 and R2 is —OH or —OAc; a process...
7968155 Optically anisotropic material, liquid crystal display device and triphenylene compound  
An optically anisotropic material comprising at least one discotic compound having a cyclopropylcarbonyl group. The material is excellent in both the wavelength dispersion property and the...
7910019 Mesogen containing compounds  
Compounds including at least one mesogenic substructure and at least one long flexible segment and methods of synthesizing the same are disclosed. Formulations which include various embodiments of...
7910020 Liquid crystal compositions comprising mesogen containing compounds  
Liquid crystal compositions comprising compounds including at least one mesogenic substructure and at least one long flexible segment and a compound selected from a photochromic compound, a...
7893270 Process for the production of cyclic diketones  
The present invention relates to a process for the preparation of compounds of formula (I), wherein the substituents are as defined in claim 1, by reacting a compound of formula (II), with a...
7875741 Site-specific inhibitors of histone methyltransferase [HMTase] and process of preparation thereof  
The present invention relates to compounds of structural formula I as site-specific inhibitors of histone methyltransferase, where R1 and R1 is —OCH3 or —OH, R2 and R2 is —OH or —OAc; a process...
7816385 Dimeric dicarboxylic acid derivatives, their preparation and use  
A novel class of dicarboxylic acid derivatives, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing...
7745099 Photosensitive compound and photoresist composition including the same  
A photosensitive compound as a molecular resist whose size is smaller than conventional polymer for photoresist, and which can form a nano assembly, and a photoresist composition including the same...
7737176 Substituted arylhexadienoic acids and esters thereof which can be used for the treatment and prevention of diabetes, dyslipidaemia and atherosclerosis, pharmaceutical compositions comprising them and processes for the preparation of them  
The invention relates to compounds of the formula I: and to the pharmaceutically acceptable salts thereof, to processes for the preparation of them and to pharmaceutical compositions comprising...
7674922 Process for production of delta-9-tetrahydrocannabinol  
The present invention relates to a process for preparation of a delta-9-tetrahydrocannabinol compound or derivative thereof involving treating a first intermediate compound with an...
7618690 Polymerizable liquid crystal compound, liquid crystal composition, optical anisotropic material and optical element  
A liquid crystal compound represented by the formula CH2═CR1—COO-(L)k-E1-E2-E3-E4-R2 wherein R1: a hydrogen atom or a methyl group; R2: a C1-8 alkyl group; k: 0 or 1; L: —(CH2)pO— or —(CH2)q...
7442418 Polymerizable liquid crystal compound, liquid crystal composition, optical anisotropic material and optical element  
The present compound represented by formula(I) CH2═CR1—COO—(L)k-E1-E2-E3-(E4)m-(E5)n-R2 (1) provided that the symbols in the formula have the following meanings: R1: a hydrogen atom or a methy...
7427685 Therapeutic substituted cyclopentanes  
Therapeutic compounds according to one of the structures below are disclosed herein.
7425603 Polymers, polymer compositions, and method of preparation  
A polymer comprising structural units derived from a polycyclic dihydroxy compound of Formula (I) wherein R1, R2 and R3 are independently at each occurrence selected from the group consisting of a...
7232821 (2-((2-alkoxy)-phenyl) -cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives  
Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein A, R1, R2, Rx, R8, R9 and n are as defined in the specification, a process for the preparation of such...
7037914 Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient  
A peroxisome proliferator activated receptor regulator containing a carboxylic acid derivative of formula (I) (wherein all symbols are as defined in the specification), a non-toxic acid thereof or...
6960681 Guanidinomethyl cyclohexane carboxylic acid ester derivatives  
The invention relates to novel and valuable intermediate compounds of the general formula (VIII) which can be used for the preparation of novel compounds comprising an antibacterial action,...
6909012 Diflunisal esters and related compounds  
O-medium alkyl esters of diflunisal and related compounds are disclosed having anti-platelet activity, hydroxy radical scavenging properties, enhanced hepatic clearance and low ulcerogenic...
6869967 Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives  
Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these...
6762315 Method for producing (1,1′,4, 11″)-terphenyl compounds  
The invention relates to a method for producing [1,1′:4′,1″]-terphenyl compounds of the formula which comprises reacting a metal aryl of the formula with a boric ester at −80 to 40° C. in the pres...
6653499 Photoactive propane derivatives and orientation layers  
Compounds of formula (I) may be used as alignment layers in liquid crystal devices wherein X1-5 are idependently selected from H, F, CN, phenylene, C1-10 alkyl, whereby when X1=X2, then X1,2=H and...
6627656 Method of treatment using phenyl and biaryl derivatives as prostaglandin E inhibitors and compounds useful therefore  
This invention encompasses a method for the treatment or prevention of prostaglandin mediated diseases comprising administering to a mammalian patient a compound of formula I: in an amount that is...
6518306 1,4-substitued 4,4-diaryl cyclohexanes  
This invention relates to compounds of Formula (I) where Z is an amine, alcohol or derivative thereof, and the ketone analog thereof.
6452022 Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids  
This invention relates to a method of preparing a compound type where at least one of R′ or R″ is a carboxyl group (I) by treating a compound of formula (II) with a Group I(a) or Group II(a) met...
6376546 Biphenyl-5-alkanoic acid derivatives and use thereof  
Compounds represented by general formula I or salts thereof, wherein n is an integer of 2 or 3; R represents a straight-chain or branched saturated alkyl group having 4 or 4 carbon atoms, a...
6369261 Compounds having activity as inhibitors of cytochrome P450RAI  
Compounds having Formula 2 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating...
6337408 Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids  
This invention relates to a method of preparing a compound of the following type by treating a compound of formula (II) with lithium bromide, magnesium bromide and the like.
6326397 Retinoid antagonists and use thereof  
The present invention relates to novel retinoid antagonists of the formula I ##STR1##wherein the dotted bond can be either hydrogenated or form a double bond; and, when the dotted bond forms a...
6307089 Biphenyl butyric acids and their derivatives as inhibitors of matrix metalloproteinases  
Biphenyl butyric acid compounds and derivatives are described as well as acid methods for the preparation and pharmaceutical compositions of same, which are useful as inhibitors of matrix...
6172239 Substituted 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors, their preparation and pharamaceutical compositions containing them  
The invention relates to compounds of the formula ##STR1##The compounds have agreat affinity for the neurotensin receptors.
6147111 Phenyl derivatives useful as endothelin receptor antagonists  
Novel phenyl derivatives which are useful as endothelin receptor antagonists.
6133469 Anti-ferroelectric liquid crystal compound  
A novel anti-ferroelectric liquid crystal compounds of the formula (1), ##STR1## wherein R is a linear alkyl group having 6 to 12 carbon atoms, X is a hydrogen atom or a fluorine atom, m is an...
6110955 Metabolically stabilized oxyalkylene esters and uses thereof  
This invention relates to compositions for and methods of treating, preventing or ameliorating cancer and other proliferative diseases as well as methods of inducing wound healing, treating...
6043232 Nitroso esters of beta-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs  
A compound comprising a non-steroidal antiinflammatory agent to which is directly or indirectly linked an NO group, a compound comprising an enolic anilide non-steroidal antiinflammatory agent to...
6013827 Compounds  
This invention relates to componds of formula I ##STR1## which are useful as PDE IV inhibitors and for treating diseases related thereto.
5994379 Bisaryl COX-2 inhibiting compounds, compositions and methods of use  
The present invention relates to inhibitors of COX-2, compositions which contain such compounds and methods of use. The compounds are represented by formula I: ##STR1## and include pharmaceutically...
5973190 Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds  
The present invention provides a process for the preparation of pesticidal fluoroolefin compounds having the structural formula I ##STR1## The present invention also provides intermediate compounds...
5968908 Restricted 9-cis retinoids  
The invention is novel analogs of 9-cis-retinoic acid which are useful for the treatment and prevention of coronary artery disease and to protect against premature atherosclerosis by increasing HDL...
5892098 3,3-(disubstituted)cyclohexan-1-one monomers and related compounds  
This invention relates to derivatives of 3,3-(disubstituted)cyclohexan-1-one monomers and related compounds which are useful for treating allergic and inflammatory diseases.
5767151 3,3-(disubstituted) cyclohexan-1-ylidine acetate dimers and related compounds  
The present invention relates to novel 3,3-(disubstituted)-cyclohexan-1-ylidene acetate dimers of Formula (I): ##STR1## and related compounds, pharmaceutical compositions containing these...
5728864 Liquid crystal compound having ferrielectric phase and liquid crystal composition  
A liquid crystal compound of the formula (1) ##STR1## wherein R is a linear alkyl group having 6 to 12 carbon atoms, both X and Y are hydrogen atoms or one of X and Y is a fluorine atom and the...
5719184 3,3-(disubstituted)cyclohexan-1-carboxylate dimers and related compounds  
The present invention relates to novel 3,3-(disubstituted)cyclohexan-1-carboxylate dimers and related compounds, pharmaceutical compositions containing these compounds, and their use in treating...
5710277 Process for R (+) 1,2,3,6-tetrahydro-4-phenyl-1- (3-phenyl-3-cyclohexen-1-yl)methyl!pyridi ne, a central nervous system agent  
An improved process for the preparation of R(+)1,2,3,6-tetrahydro-4-phenyl-1- (3-phenyl-3-cyclohexen-1-yl)methyl!pyri dine by a novel synthesis is described where...
5691376 Substituted biphenyl derivatives  
A compound of the following structure: ##STR1## wherein R8 =H: R1 =alkyl, cycloalkyl, arylalkyl, aryl; R2 =cycloalkyl, aryl, C3 -C10 alkyl; X,Y=O, S(O)n, NH; Z=CO2 R3, C(O)CO2 R3, CH(OH)CO2 R3,...
5663413 Biphenyl iodinated derivatives and their diagnostic use  
The invention relates to novel contrast media particularly useful for X-ray diagnostic investigations of human and animal body.
5536845 Acrylates containing an alcohol, aldehyde and/or ether functional group, process for their manufacture and their application to the production of new polymers and copolymers  
Process for the preparation of the acrylates chosen from those of formula ##STR1## those of formula ##STR2## and those of the formula ##STR3## useful in the production of new polymers and copolymers.
5494605 P-terphenyl derivatives and liquid crystalline compositions  
The p-terphenyl derivatives of the formula shown below are useful in preparing practical ferroelectric liquid crystalline compositions. The derivatives exhibit excellent chemical stability and...
5475132 Antifungal agents based on amides containing a phenyl group  
R3, R4 and R5, each represents a hydrogen or halogen atom (at least one of R3, R4 and R5 being other than hydrogen or halogen); optionally substituted amino; optionally halogenated or hydroxylated...
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