|
Match
|
Document |
Document Title |
|
|
7459585 |
Benzene derivatives and pharmaceutical use thereof
The present invention provides an AP-1 activation inhibitor, NF-kappa B activation inhibitor, inflammatory cytokine production inhibitor, matrix metalloprotease production inhibitor, inflammatory...
|
|
|
7320998 |
Carbohydrate analog inhibitors of alpha-amylase
The present invention provides carbohydrate analogs of the formula:
wherein X is CH 2 , O, or NH, and R 1-8 are independently H, a short hydrocarbon, a substituted amine, an alcohol, a...
|
|
|
7253210 |
Methylene-bridged selective androgen receptor modulators and methods of use thereof
This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the...
|
|
|
7220781 |
Meta-benzamidine derivatives as serine protease inhibitors
Compounds of formula I
in which R 1 , R 2 , R 3 , each X, L, Y, Cy, Lp, D and n have the meanings as set out in the specification, and corresponding compounds in which the unsubstituted or...
|
|
|
7034015 |
Aminobenzoephenones
The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating...
|
|
|
6852738 |
Acyl sulfamides for treatment of obesity, diabetes and lipid disorders
A class of acyl sulfamides comprises compounds that are potent ligands for PPAR gamma and generally have antagonist or partial agonist activity. The compounds may be useful in the treatment,...
|
|
|
6849626 |
Aza-amino acid derivatives (factor Xa inhibitors 15)
The invention relates to semicarbazides of the general formula I
where R 1 , R 2 , R 3 , R 4 and I have the meaning indicated in claim 1.
The compounds of the formula I can be employed...
|
|
|
6767922 |
IL-8 receptor antagonists
This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
|
|
|
6534542 |
(2-hydroxy)ethyl-thioureas useful as modulators of α2B adrenergic receptors
Compounds of formula (i) and of formula (ii) wherein the symbols have the meaning disclosed in the specification, specifically or selectively modulate α 2B and/or α 2C adrenergic receptors...
|
|
|
6323227 |
Substituted N-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides
This invention relates to compounds of formula ##STR1## which inhibit Factor Xa, to pharmaceutical compositions containing the compounds, and to the use of the compounds for the treatment of...
|
|
|
6225334 |
Glyoxylic acid derivatives
The invention concerns novel glyoxylic acid derivatives, a process for their preparation and their use as pesticides.
|
|
|
6218536 |
1,2-bis-adducts of stable nitroxides with substituted ethylenes and stabilized compositions
1,2-Bis-adducts of stable hindered nitroxide compounds with substituted ethylenes are prepared by reacting two equivalents of nitroxyl compound with an ethylenically unsaturated compound such as...
|
|
|
6187955 |
Guanidine derivatives and process for their production
A guanidine derivative represented by formula (1), (2), (3) or its acid addition salt and a production process thereof ##STR1## wherein each of A and B is a C 2 -C 8 alkylene, D is a single bond,...
|
|
|
6143790 |
L-N.sup.6 -(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors
There is disclosed a novel amino glycol derivatives of L-N 6 -(1-iminoethyl)lysine, pharmaceutical compositions containing these novel compounds, and to their use in therapy, in particular their...
|
|
|
6140361 |
Use of 2-deoxystreptamine as a molecular scaffold for the preparation of functionally and spatially diverse molecules and pharmaceutical compositions thereof
2-Deoxystreptamine is an aminocyclitol whose structural stability and abundant functionality make it an attractive scaffold for the combinatorial generation of small molecules. The ability to...
|
|
|
6124270 |
Use of a cationic amphipathic compound as a transfection agent, vaccine additive or drug
A cationic amphipathic compound of formula (I), ##STR1## wherein A is a single bond, an NH--R' grouping or (a), wherein --R'-- is a straight or branched, optionally substituted, saturated or...
|
|
|
6077970 |
Carboxylic acid esters of 2-hydroxy-5-isoalkyl-beta-methylstyrene
The present invention relates to carboxylic acid esters of 2-hydroxy-5-isoalkyl-beta-methylstyrenes wherein the said isoalkyl substituent comprises 8-18 carbon atoms.
|
|
|
5837873 |
Intermediates of retroviral protease inhibiting compounds
A retroviral protease inhibiting compound of the formula A--X--B is disclosed. Also disclosed are a composition and method for inhibiting a retroviral protease and for treating an HIV infection....
|
|
|
5798383 |
Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas
The prevent invention provides a compound of formula (I): ##STR1## wherein Ar is (a) phenyl, naphthyl and biphenyl, each optionally substituted with C 1 -4 alkyl, C 1 -4 haloalkyl, C 1 -4...
|
|
|
5723655 |
Amine compound and detergent composition containing the same
The present invention relates to an amine compound represented by the following general formula (1): ##STR1## wherein R 1 and R 2 represent individually a linear or branched C 1 -C 24 alkyl or...
|
|
|
5705681 |
Diquaternary compounds useful as bleach activators
Diquaternary ammonium esters useful as bleach activators are disclosed as are bleach compositions comprising such an ester and peroxygen compound yield peroxide in solution.
|
|
|
5698740 |
Hole-transport material
A hole-transport material having excellent hole-transport capability and durability, suitable for use in an organic EL device and as an organic photoconductive material, has the formula (1).
|
|
|
5662827 |
Diquaternary compounds useful as bleach activators, and compositions containing them
Disclosed are bleaching compositions comprising diquaternary ammonium esters which are useful as bleach activators with a peroxygen compound to yield peroxide in solution.
|
|
|
5631401 |
Inhibitors of protein farnesyltransferase and squalene synthase
The present invention provides a compound of the formula ##STR1## or a pharmaceutically acceptable salt thereof, which are useful in inhibiting protein farnesyltransferase and the farnesylation of...
|
|
|
5606092 |
Monoazo compounds and method for dyeing or printing fiber materials using the same
A monoazo compound of the following formula, ##STR1## wherein D is phenylene or naphthylene; X is halogeno, pyridinio or ##STR2## B is --OR 3 , --SR 4 , ##STR3## in which R 3 , R 4 , R 5 and R 6 ...
|
|
|
5514642 |
Cyclohexenone oxime ethers, their preparation and their use
Cyclohexenone oxime ethers of the formula I ##STR1##
|
|
|
5457108 |
5-oxo-dibenzo[a,d]cyclohepta-1,4-dienes
The invention relates to substituted 5-oxo-di-benzo[a,d]cyclohepta-1,4-dienes of the formula (I) ##STR1## processes for their preparation and their use as retroviral agents.
|
|
|
5446067 |
Oxime ethers and fungicides containing them
Oxime ethers of the formula ##STR1## wherein m, G, R, R 1 , X, Y, and Z are as defined herein and fungicides containing these compounds.
|
|
|
5440060 |
Surface-active compounds based on alkoxylated fatty amines
The demands on the properties of pigments, in particular in the areas of emulsion paints and printing inks, which are continuously becoming more specific made it necessary to develop selective and...
|
|
|
5405997 |
Antiarrhythmic methanesulfonamides
Methanesulfonamides are structurally depicted by Formula I' ##STR1## or its pharmacologically acceptable salts where R 3 is a C 1 -7 alkyl substituted with C 3 -7 cycloalkyl, or a C 1 -10 alkyl...
|
|
|
5403850 |
Derivatives of P-substituted phenyl ester of pivalic acid
A derivative of general formula: ##STR1## wherein Y is --SO 2 --or ##STR2## (i) R 1 and R 2 , which may the same or different, each represent, (1) --H, (2) C1-16 alkyl or (3) the formula ##STR3##...
|
|
|
5399746 |
Diquaternary bleach activators and compositions containing them
Diquaternary ammonium esters useful as bleach activators are disclosed, as are bleach compositions comprising such an ester and a peroxygen compound which yields peroxide in solution.
|
|
|
5395971 |
Molybdenum-catalyzed amination of olefins
A process for making unsaturated α-amines from olefins wherein the process includes adding an aminating agent, an olefin and a molybdenum based catalyst to a reaction vessel having a nitrogen...
|
|
|
5380941 |
Preparation of aromatic ureas which contain a thioether or sulfonyl group
A process for preparing ureas of the formula ##STR1## where the ring A can be substituted and benzo-fused and n is 0 or 2, R 4 and R 5 are hydrogen, C 1 -C 4 -alkyl or phenyl, L is...
|
|
|
5371278 |
Synthesis of ioversol using a minimal excess of acetoxyacetylchloride
The use of a minimal excess of acetoxyacetylchloride as a reagent in the synthesis of N,N'-bis(2,3-dihydroxypropyl)-5-N-(2-hydroxy-ethyl)glycolami
do-2,4,6-triio doisophthalamide.
|
|
|
RE34805 |
Benzonaphthalene derivatives and their use in therapeutic and cosmetic compositions
A benzonaphthalene compound has the formula ##STR1## wherein R 1 represents ##STR2## or (ii) --CH 2 OH; R 6 represents ##STR3## or OR 7 wherein R 7 represents hydrogen, alkyl having 1-20...
|
|
|
5359128 |
Malic acid derivatives and compositions for the treatment of psoriasis
The invention comprises compositions and methods for the treatment of psoriasis. The compositions comprise compounds of the formula: ##STR1##
|
|
|
5354882 |
Doubled phenyl- or naphthyl-azobenzenes having a plurality of reactive groups and intermediates therefor
The reactive dyes have the formula ##STR1## where n is 0 or 1, R 1 , R 2 and R 3 are each hydrogen, C 1 -C 4 -alkyl or phenyl, R 4 is fluorine, chlorine, bromine, C 1 -C 4 ...
|
|
|
5334761 |
Cationic lipids
The present invention discloses cationic lipids useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent...
|
|
|
5326902 |
Oxyalkyne compounds, pharmaceutical compositions containing them and processes for preparing such compounds and compositions
Oxyalkyne compounds corresponding to the formula I ##STR1## in which the substituent Y in the meta- or para-position is R 1 represents CH 3 or NH 2 , R 2 represents H or CH 3 , R 3 represents...
|
|
|
5326786 |
5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxobenzo[alpha]heptalene derivative and pharmaceutical use
Compounds represented by the formula ##STR1## wherein R 1 and R 2 each represent a hydrogen atom or a protective group for a hydroxyl group, or R 1 and R 2 combine to represent a protective...
|
|
|
5306837 |
Intermediates for an optically active cyclobutane nucleoside
Novel intermediates useful in the preparation of the optically active antiviral compound [1R-(1α,2β,3α)]-2-amino-9-[2,3-bis(hydroxymethyl)cyclobut
yl]-1,9-dihydro-6H-purin-6-one are described.
|
|
|
5270472 |
Alkanoyl L-carnitine amides with aminoacids and pharmaceutical compositions containing same for promoting regeneration of the nervous tissue, inhibiting neuronal degeneration, enhancing the process of learning and memory and for the treatment of coma
Amides of alkanoyl L-carnitines of general formula (1). ##STR1## wherein R is a straight or branched alkanoyl group having from 2 to 8 carbon atoms selected from acetyl, propionyl, butyryl,...
|
|
|
5256806 |
Intermediates for the preparation of optically active cyclobutane nucleoside
Novel intermediates useful in the preparation of the optically active antiviral compound [1R-(1α,2β,3α)]-2-amino-9-[2,3-bis(hydroxymethyl)cyclobut
yl]-1,9-dihydro-6H-purin-6-one are described.
|
|
|
5256393 |
Use of azeotropic distillation in process to dry 5-amino-N,N'bis (2,3-dihydroxypropyl)-2,4,6-triiodoisphthalamide
The use of azeotropic distillation to dry 5-amino-N,N'bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthala
mide, an intermediate in the production of...
|
|
|
5202464 |
Optically active aminocyclitols
Inositol compounds grouped into an aminocyclitol family are disclosed which have stereospecific structure and optical activity and find application to the manufacture of medicinal products and...
|
|
|
5175257 |
Radiolabeled proteins for diagnostic or therapeutic use
Chelating compounds of specified N 2 S 2 N 3 S derived structure are useful for radiolabeling targeting molecules such as antibodies. Cleavable ester orthioester linkers connect the radionuclide...
|
|
|
5155271 |
Process for the alkylation of aromatic amines
The invention relates to a process for the preparation of compounds of the formula ##STR1## in which Q is substituted or unsubstituted C 1 -C 6 alkyl, A is a direct bond or a bridging member, s...
|
|
|
5152916 |
Aqueous aldehyde solutions for trapping hydrogen sulfide in natural gas and crude oil producing plants
Aqueous aldehyde solutions for trapping hydrogen sulfide comprising 5 to 50% by weight of an aldehyde and 1 to 5% by weight, relative to the aldehyde solution of a formulation comprising 10 to...
|
|
|
5117057 |
Insecticidal N' substituted-N-N'-disubstituted-hydrazines
This invention relates to insecticidal compositions containing N'-substituted-N,N'-disubstitutedhydrazines, methods of using such compositions and N'-substituted-N, N'-disubstitutedhydrazines....
|