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4316044 |
Isovaleric acid derivatives
Isovaleric acid derivatives having the formula ##STR1## wherein typical representations of X is halophenyl, R 1 is hydrogen or cyano, R 2 is hydrogen or lower alkyl, and Y is halophenyl. These...
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4313956 |
Novel sypathomimetic amine prodrugs
Novel, transient prodrug forms of the phenolic dihydroxy sympathomimetic amines have (i) the structural formula (I): ##STR1## wherein X is O, S or NR 5 ; n is 1 or 2; R 1 is the...
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4311706 |
Novel dopa/dopamine prodrugs
Novel, transient prodrug forms of dopa and dopamine have (i) the structural formula (I): ##STR1## wherein each R is independently selected from the group consisting of hydrogen, R 3 -CO- and...
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4309350 |
Process of making phenylacrylic esters
The (+), (-) and (±) forms of the compounds of formula I ##STR1## wherein R 1 is hydrogen or a methoxy, ethoxy, propoxy, methylthio, ethylthio, propylthio, fluoro, chloro, bromo, methyl, ethyl,...
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4301044 |
Biodegradable zwitterionic surfactant compounds
Zwitterionic surfactant compounds are made readily biodegradable in the environment by the inclusion of a biochemically and/or hydrolytically labile chemical linkage located between the cationic...
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4296254 |
Transetherification in amides
The disclosure herein pertains to the preparation of N-(alkoxymethyl)- and other N-methylene ether-substituted 2-haloacetamides from other N-methylene ether-substituted 2-haloacetamides and the...
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4291061 |
1H-inden-1-one derivatives, processes for producing them, their use in microbicidal compositions, and for combating microorganisms
2,3-Dichloro-7-hydroxy-1H-inden-1-one derivatives of the formula I ##STR1## wherein R 1 is hydrogen or one of the groups ##STR2## R 2 and R 3 independently of one another are each hydrogen,...
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4289894 |
Pentachlorophenyl-phenyl malonate compound suitable for use as acylating agents
Compounds of the formula: ##STR1## are disclosed wherein R is C 1 to C 6 alkyl, C 1 to C 6 haloalkyl, C 3 to C 8 cycloalkyl, phenyl, halophenyl, naphthyl, benzyl, indanyl, phenacyl,...
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4288612 |
Deposit control additives
Deposit control additives for internal combustion engines are provided which maintain cleanliness of intake systems withcut contributing to combustion chamber deposits. The additives are...
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4278598 |
Positive-working immobile intramolecular nucleophilic displacement compounds and photographic elements containing same
Novel photographic dye release compounds have the structure: ##STR1## wherein R 1 is an aromatic group containing 5-7 members in the ring to which Nu and E are attached; R 2 and R 3 are bivalent...
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4271187 |
Substituted phenyl alanine antihypertensive agents
A compound of the formula ##STR1## possesses antihypertensive activity. Also provided are methods for the preparation of the compounds as well as pharmaceutical formulations and methods for their...
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4266074 |
Novel insecticidal composition
Substituted acetate compounds represented by the formula ##STR1## which are useful as pesticides and pesticidal composition containing the substituted acetate compounds as active ingredients, as...
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4266069 |
Processes for the preparation of hydratropic acids and esters
The invention concerns the novel compounds dialkyl 2-(3-fluoro-4-nitrophenyl)-2-methylmalonate IIIa and dialkyl 2-(3-fluoro-4-aminophenyl)-2-methylmalonate IVa useful as intermediates in an...
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4266082 |
Preparation of 4-fluoro-3-phenoxy-toluene
A process for the preparation of 4-fluoro-3-phenoxy-toluene of the formula ##STR1## comprising reacting 3-bromo-4-fluoro-toluene, of the formula ##STR2## with potassium phenolate, or with sodium...
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4255329 |
Double receptor fluorescent immunoassay
A novel sensitive method for determining qualitatively and quantitatively the presence of a wide variety of physiologically active organic compounds (ligand) and their receptors is provided. The...
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4252945 |
Process for preparing pyrazolo[1,5-c]-quinazoline derivatives and novel intermediates
A process is provided for preparing pyrazolo-[1,5-c]quinazoline derivatives of the structure ##STR1## wherein X is O or S; R 1 is hydrogen, lower alkyl, hydroxymethyl, phenyl-lower alkyl, phenyl...
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4252979 |
Terephthalic acid derivatives
The novel compounds of the formula: ##STR1## wherein R 1 and R 2 are each either hydrogen or an alkyl group containing from 1 to 4 carbon atoms, and maybe the same or different, are useful...
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4250183 |
N-(Substituted amino)alkanoyl-aminoalkanoic acids and salts, their use and their compositions
N-substituted ω-aminoalkanoyl-ω-aminoalkanoic acids and their pharmacologically-acceptable salts (with a base) are useful, e.g., in pharmaceutical-composition form for the treatment or...
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4245114 |
Glycol ester preparation
In the preparation of glycol esters by the liquid phase reaction of an olefin, molecular oxygen, and a carboxylic acid in the presence of a catalyst system comprising a variable valent cation in...
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4243678 |
Acylhydrocarbylaminoalkanoic acids, compositions and uses
Compounds of the formula ##STR1## wherein R is (a) optionally-substituted and optionally-hydrogenated biphenylyl, (b) optionally-substituted and optionally-hydrogenated bicyclic aryl having from 8...
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4242357 |
Carboxylic acid esters for combating pests
3-Phenoxybenzyl alcohols and carboxylic acid esters thereof for combating pests of the formula ##STR1## in which R and R 1 are different and each represent hydrogen, fluorine or bromine, R 2 ...
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4237322 |
Process for preparation of 1,5-dimethylbicyclo[3,2,1]octan-8-ol
A process for the preparation of 1,5-dimethylbicyclo[3,2,1]octan-8-ol is described wherein 1,5-dimethyl-1,5-cyclooctadiene is reacted with a carboxylic acid in the optional presence of acid...
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4229368 |
Esters and thiolesters of unsaturated acids
Esters and thiolesters of α-substituted unsaturated acids, intermediates therefor, synthesis thereof, and the use of said esters and thiolesters and compositions thereof for the control of pests.
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4227015 |
Substituted phenylvinyl cyclopropyl ketones
Aryl substituted diketones and keto-esters, useful as antiviral agents and insecticides, are prepared by reacting an arylalkyl or arylalkenyl iodide with a metal salt of the appropriate diketone or...
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4225521 |
Herbicidal phosphonates
This invention relates to phosphorus containing compounds which are useful as herbicides. Additionally, they demonstrate tolerance towards desired crops, e.g., cotton, soybeans and sugarbeets.
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4221918 |
Preparation of diesters
Carboxylic acid anhydrides are contacted with hydrogen in the presence of an insoluble metal hydrogenation catalyst and strong protonic acid to produce 1,1-diesters.
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4220590 |
Asymmetric catalysis
New optically active bis phosphine compounds which are usful in optically active catalysts. Such catalysts are particularly useful in catalytic asymmetric hydrogenation.
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4219660 |
Conjugated diene derivatives
There are disclosed herein derivatives of bisfunctionalized compounds, wherein said compounds have been formed by the introduction of a nitro group and a hydroxyl group in the form of an ester into...
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4218369 |
Cycloammonium-azo-phenyl-dyestuffs containing one cyanoethyl, carbamoylethyl or carbalkoxyethyl group on the phenyl radical
The invention relates to new cationic azo dyestuffs which correspond to the general formula: ##STR1## in which R 1 represents an alkyl radical or a substituted alkyl radical, R 2 represents a...
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4218469 |
Combating arthropods with 3-phenoxy-fluoro-benzyl carboxylic acid esters
3-Phenoxy-fluoro-benzyl carboxylic acid esters of the formula ##STR1## in which R 2 is hydrogen, cyano or ethynyl, R 3 is ##STR2## R 4 and R 5 represent chlorine, bromine or methyl, and R 6 ...
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4216337 |
Process for preparing esters
A process for preparing esters which comprises reacting a polycarboxylic acid with an alcohol, removing the unreacted alcohol from the resultant esterification reaction mixture, heating the crude...
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4216109 |
Liquid crystal composition and method for making same
A new and novel liquid crystal composition having broad temperature and chemical stability is disclosed. The liquid crystal composition comprises a compound having the general formula: ##STR1## (R...
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4200580 |
Dioxanylphenyl benzoate liquid crystal compounds
Compounds of the formula: ##STR1## wherein R 1 is a straight chain alkyl group of 1 to 10 carbon atoms and R 2 is an alkyl, alkoxy, acyloxy, alkyl carbonato group having 1 to 10 carbon atoms, CN...
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4199596 |
Combating arthropods with fluorine-substituted phenoxybenzylcarbonyl derivatives
Fluorine substituted phenoxybenzylcarbonyl derivatives of the formula ##STR1## in which R 1 represents hydrogen, cyano or ethynyl and R 2 represents the radical ##STR2## wherein R 3 and R 4 ,...
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4197254 |
Derivatives of N-phosphonomethylglycine
A new class of compounds, prepared by reacting a salt of N-phosphonomethylglycine with a cyclic anhydride, have utility as post-emergent herbicides.
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4182761 |
Acyloxy-substituted aryloxyalkyl diketones
Acyloxy-substituted aryloxyalkyl diketones, useful as anti-viral agents, are prepared either by esterification of the corresponding hydroxy-substituted compounds or by reacting a haloalkyl diketone...
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4182899 |
Optical resolution of amino acids into optical antipodes
The present application relates to the optical resolution into optical antipodes of compounds of the formula ##STR1## as well as to salts consisting of an optical isomer of a compound of the above...
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4175947 |
Phenoxy-phenoxypropionic acid esters
Phenoxy-phenoxypropionic acid derivatives of the formula ##STR1## wherein R is hydrogen or halogen, and R 1 is substituted alkyl, cyclohexenyl, phenylalkenyl or (substituted) alkinyl, are...
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4172098 |
Manufacture of substituted halobenzenes
Halobenzenes are manufactured by (a) a one-vessel reaction of anilines with halogenating agents to give haloanilines, followed by reaction of the mixture thus obtained with alkanols and...
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4172147 |
3,5-Dinitro oxanilic acid ester compounds, compositions and methods
Novel compounds of the formula ##STR1## wherein R is alkyl of one to eight carbon atoms, inclusive, are formulated into pharmaceutical compositions suitable for oral or parenteral administration...
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4171423 |
Derivatives of ester diol alkoxylates and compositions thereof
Derivatives of esterdiol alkoxylates obtained by reaction thereof with an anhydride, isocyanate or epoxide, as well as the anhydride capped products of the derivatives of the two latter....
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4156694 |
Benzobicyclononene derivatives
The present invention relates to novel benzo(b) bicyclo[3.3.1]nones of the general formula I: ##STR1## and a salt or nitrogen oxide thereof, in which R 1 and R 2 stand for hydrogen, alkyl of 1-6...
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4154842 |
Fungicidally and bactericidally active 1-azolyl-4-hydroxy-1-phenoxy-butane derivatives
1-Azolyl-4-hydroxy-1-phenoxy-butane derivatives of the formula ##STR1## in which R is hydrogen, --CO--R 1 or --SO 2 --R 2 , R 1 is cycloalkyl, alkylamino, dialkylamino, alkenyl, alkynyl, or...
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4150019 |
Water-insoluble yellow terephthalate-azo-acetoacetylamido-benzimidazolone dyestuffs
Water insoluble yellow monoazo dyestuffs of the general formula 1 ##STR1## in which R 1 represents alkyl, cycloalkyl or aralkyl, X represents a carboxylic acid ester or a carboxylic acid amide,...
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4124619 |
Preparation of esters of hydroxy tiglic aldehyde
Preparation of carboxylic acid esters of γ-hydroxy-tiglic-aldehyde from bismonocarboxylic acid esters of but-2-en-1,4-diol via 1,4-diacetoxy-2-formyl butane including intermediates in this synthesis.
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4122026 |
Liquid crystal mixtures
A nematic liquid crystal mixture comprises at least one nematic liquid crystal compound and an amount, sufficient to impart a positive DC anisotropy of at least about 15 to said mixture, of at...
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4103025 |
Novel terpenes
Pharmaceutically active compounds of the formula ##STR1## wherein --OR 1 , --OR 2 , --OR 3 and --OR 4 , which may be the same or different, each represents a free or esterified hydroxyl group and...
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4100350 |
3-Substituted propanoic acid derivatives
The invention provides 3-(2-formyl-3-hydroxy-5-oxocyclopent-1-enyl)-p ropanoic acid and derivatives thereof having anti-thrombotic activity coupled with low toxicity. Also provided is a method for...
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4095029 |
2-Hydroxy-3-alkylsulfoxypropyl-1 esters of arene polycarboxylic acids
2-Hydroxy-3-alkylsulfoxypropyl-1 esters of arene polycarboxylic acids.
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4093658 |
Process for the preparation of aromatic polyamines
The instant invention is directed to a novel process for the production of aromatic polyamines. In one embodiment, the process comprises (A) condensing an aromatic amine with formaldehyde in the...
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