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7605286 |
Hydroxy-protecting reagent and method of protecting hydroxy with the same
The present invention relates to a method of protecting a hydroxyl group, which includes reacting a hydroxyl group-containing compound with a compound represented by the formula (I):
wherein R...
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7582791 |
Process for producing optically active ester
A process for producing an optically active 2-hydroxybutyric ester (1), characterized by including reacting an optically active 2,3-epoxybutyric ester (2) with a thiol in the presence of scandium...
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7569631 |
Method for producing fluorine-containing polymer, aqueous dispersion of fluorine-containing polymer,2-acyloxycarboxylic acid derivative, and surface active agent
The present invention provides a method of producing a fluoropolymer, wherein polymerization using a carboxylate ester bond-containing carboxylic acid derivative as a surfactant in an aqueous...
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7550617 |
Compositions and methods for the treatment of renal and cardiovascular disease
Derivative compounds of 11-nonyloxy-undec-8(Z)-eonic acid that mimic epoxide metabolites are provided. Also provided are compositions comprising a therapeutically effective amount of the derivative...
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7531683 |
Continuous process for the cyanation of hydrogenated β-ketoesters
The present invention relates to a continuous process for the cyanation of hydrogenated β-ketoesters in a cyanation zone maintained under conditions of temperature and pressure effective for...
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7528277 |
Method to produce a carboxylic acid ester from a carboxylic acid ammonium salt by alcoholysis
The present invention relates to a method for obtaining a carboxylic acid ester from an aqueous solution of the corresponding carboxylic acid ammonium salt using alcoholysis. The recovered...
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7459581 |
Anti-bacterial compounds
Ester compounds of the formula I-a
wherein R 1 is selected from OH, NH 2 and NH 3 + X − , wherein X is an inorganic anion, wherein R 2 is a singly-branched saturated or unsaturated...
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7381834 |
Method for stabilizing menthyl lactate
A method for stabilizing menthyl lactate is disclosed. The method comprises combining water with a solution comprising menthyl lactate and a water-miscible organic solvent in amounts effective to...
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7348451 |
Additives for inhibiting gas hydrate formation
The invention provides the use of compounds of the formula (1)
where
R 1 , R 2 are each independently C 1 - to C 22 -alkyl, C 2 - to C 22 -alkenyl, C 6 - to C 30 -aryl or C 7 - to C 30...
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7345190 |
Carnitine conjugates as dual prodrugs and uses thereof
The present invention discloses novel dual prodrug compositions of Formula 1,
wherein A is a single bond, —O—, or —CH 2 —; m and n vary from 0 to 15; p and q vary from 0 to 4; B is a...
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7339073 |
Method for obtaining 5-halogenolaevulinic acid alkyl esters
A method for obtaining a 5-bromolevulinic acid methyl ester or a 5-chlorolevulinic acid methyl ester from either a bromination mixture or a chlorination mixture, containing either a...
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7297809 |
Continuous method for preparing ethyl lactate
The invention concerns a continuous method for preparing ethyl lactate by esterifying lactic acid with ethanol, in the presence of a catalyst which comprises reacting said lactic acid with ethanol...
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7294601 |
Phosphines, transition metal complexes containing the same as the ligand, and process for production of optically active carboxylic acids
[PROBLEMS] To provide a method by which desired optically active carboxylic acids may be prepared from a carboxylic acid having a carbon-carbon double bond through asymmetric hydrogenation with a...
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7189558 |
Process for producing pravastatin sodium salt using streptomyces flavidovirens dsm 14455
In one aspect, the present invention provides an improved method for the manufacture of Pravastatin sodium salt by fermentation under optimal fermentation parameters using a new strain of ...
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7186856 |
Process for preparing carboxylic acids and derivatives thereof
Processes for preparing carboxylic acids and derivatives thereof in which an ammonium salt of the carboxylic acid is heated in the presence of an organic reagent to split the salt and form the acid...
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7186272 |
Condensation products of hydroxycarboxylic acids and glycols or glycerol
The invention relates to reaction products of glycols, diglycols, higher glycols or glycerol with α-hydroxycarboxylic acids in a molar ratio of 1:2 or higher, especially conforming to the general...
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7135582 |
Transition metal complex having diphosphine compound as ligand
A transition metal complex having 2,2′-bis[bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-
1,1′-binaphthyl as a ligand. The presence of the transition metal complex in the reaction system of...
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7122698 |
Method for producing α-hydroxycarboxylate
The present invention provides a process for more efficiently producing an α-hydroxycarboxylic acid ester wherein side reactions due to the α-hydroxycarboxylic acid ester are inhibited or...
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7101909 |
Calcium channel drugs and uses
Novel multibinding compounds are disclosed. The compounds of this invention comprise 2–10 ligands covalently connected, each of the ligands being capable of binding to a ligand binding site in a...
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7057064 |
Continuous process for the enantioselective catalytic hydrogenation of β-ketoesters
The present invention relates to a continuous process for the enantioselective catalytic hydrogenation of β-ketoesters comprising providing a catalytic hydrogenation zone and maintaining it under...
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7057038 |
Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids
One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic...
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7038075 |
Production method of racemic 3-hydroxy-3-(2-phenylethyl)hexanoic acid C1-6 alkyl ester
The present invention relates to a production method of (R)-3-hydroxy-3-(2-phenylethyl)hexanoic acid which comprises optical resolution of racemic 3-hydroxy-3-(2-phenylethyl)hexanoic acid with an...
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7034015 |
Aminobenzoephenones
The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating...
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7005536 |
Method for producing diol derivatives
A method of producing a diol derivative efficiently and to high purity is provided. Specifically, the present invention relates to a method of producing a diol derivative having, as a fundamental...
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6967257 |
Method of purifying lactic acid esters
The invention relates to a method of purifying lactic acid esters, wherein an impure lactic acid ester is subjected to a melt crystallization. The impure lactic acid contains not more than 10 wt. %...
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6958411 |
Nordihydroguaiartic derivatives for use in treatment of tumors
Nordihydroguaiaretic acid derivatives and methods of use thereof for the treatment of tumors.
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6903233 |
Process for producing optically active 3-halogenocarboxylic acid ester and 3-azidocarboxylic acid ester
A process for producing an optically active 3-azide-carboxylic acid ester by reacting an optically active 3-hydroxycarboxylic acid ester and a thionyl halide in the presence of a basic substance in...
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6888021 |
Hydrogenation of benzenepolycarboxylic acids or derivatives thereof using a catalyst containing macropores
A process for producing plasticizers in which a phthalic acid having the CAS Nos. 111381-89-6, 111381-90-9, 111381-91-0, 68515-44-6, 68515-45-7 and 3648-20-7, the formed plasticizers and a method...
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6858749 |
Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one
The present invention relates to a novel process for producing a δ-lactone of the formula:
using an acyl halide of the formula:
wherein R 1 , R 2 R 3 and X are described herein, as...
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6825379 |
Method for recovering and producing C4-C6 dicarboxylate from alkaline waste solution generated in caprolactam preparation process
The present invention relates to a method for recovering and producing C 4 -C 6 dicarboxylates from an alkaline waste solution generated in a caprolactam preparation process, in which the alkaline...
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6825377 |
Method for the dihydroxylation of olefins using transition metal catalysts
This invention relates to process for dihydroxylation of olefins using transition metal catalysts to obtain monofunctional, bifunctional, and/or polyfunctional 1,2-diols of the formula (I) R 1 R 2...
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6815559 |
Process for producing 3,3,3-trifluoro-2-hydroxypropionic acid or its derivative
The invention relates to a process for producing 3,3,3-trifluoro-2-hydroxypropionic acid. This process includes the step of (a) bringing a 1,1-dihalogeno-3,3,3-trifluoroacetone into contact with a...
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6811722 |
Glycerin triester plasticizer
The present invention provides a phthalate-free plasticizer for polymer resins. The phthalate-free plasticizer according to the invention includes a mixture of different triesters of glycerin, at...
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6794532 |
Hydrogenation of prochiral ketones
Process for enantioselectively hydrogenating prochiral ketones to (S)-alcohols using platinum catalysts in the presence of cinchonines or quinidines as modifiers and in the presence of hydrogen,...
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6743914 |
Kinetic resolutions of chiral 2-and 3-substituted carboxylic acids
One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic...
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6730768 |
Methods of preparing casting resins and coating compositions using polyols derived from high oleic acid content fatty acid mixtures
A method for preparing a polyol useful in the formation of an isocyanate casting resin or coating composition is presented involving the reaction of an essentially C 18 fatty acid mixture with a...
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6720447 |
Method for the production of esters
The present invention relates to a novel process for the preparation of esters of the general formula I from compounds of the general formula II contained in aqueous solutions which comprises...
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6720445 |
Acetyloxymethyl esters and methods for using the same
Novel acetyloxymethyl esters are disclosed. Methods of treating an illness, including cancer, hemological disorders and inherited metabolic disorders, and treating or ameliorating other conditions...
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6667340 |
Inhibitors of phosphatidyl myo-inositol cycle
The present invention relates to the preparation and biological activity of 3-deoxy-Dmyo-inositol ether lipid analogs as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell...
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6664413 |
Process for production of esters
A process for producing an ester comprises the steps of: (a) feeding to a first vessel a feed that comprises organic acid, alcohol, and water, whereby organic acid and alcohol react to form...
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6653503 |
Microwave irradiation process for preparing methyl esters
An accelerated process for preparing a methyl ester having formula (III) said process comprising reacting a carboxylic acid or salt thereof having formula (I) with dimethyl carbonate having...
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6646152 |
Method of producing 2-hydroxycarboxylic acid esters
A process for preparing 2-hydroxycarboxylic esters having a quaternary β-carbon atom by reaction of glycidyl esters with an organoaluminum reagent is described.
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6646135 |
Continuous process for the enantioselective hydrogenation of alpha ketocarbonyl compounds
The invention relates to a continuous process for enantioselective catalytic hydrogenation of an alpha ketocarbonyl compound such as alpha ketoesters and alpha ketolactones to produce an alpha...
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6639095 |
Process for preparing optically active α-hydroxy acids and derivatives thereof
The present invention provides a process for preparing optically active α-hydroxy acids and derivatives thereof by subjecting the alkylated 1,3-dioxolanones of formula (IV) wherein R 1 and R 2 ...
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6627768 |
Process for recovery of acid
The invention provides a process for the conversion of an extracted carboxylic acid to a non-ionized derivative thereof, comprising contacting a carboxylic acid containing aqueous solution with a...
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6610177 |
Apparatus and process for the high yield production of methyl methacrylate or methacrylic acid
A high yield process for the production of methyl methacrylate or methacrylic acid and an apparatus for increasing the yield in a process for the production of methyl methacrylate or methacrylic...
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6608230 |
Single-stage method for producing α-hydroxy ethers by oxidizing C&equals C unsaturated compounds with hydroperoxides
A single-stage method for producing α-hydroxy ethers by oxidizing olefinic substrates with organic hydroperoxides and opening the resultant oxirane ring by means of monovalent or polyvalent...
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6605716 |
Process for the preparation of hydroxy and amino compounds
A process for the preparation of hydroxy and amino compounds, in which, in a first step, an aldehyde, ketone or imine is reacted in a Reformatsky reaction with a reactive halogen compound and zinc,...
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6600065 |
Process for preparing 3-hydroxyesters from epoxide derivatives
Disclosed herein is a novel process for preparing 3-hydroxyesters, comprising: (a) reacting an epoxide derivative with carbon monoxide and alcohol in a solvent at a temperature of 30˜150° C....
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6586357 |
Heteroaromatic diphosphines as chiral ligands
Chiral diphosphines constituted by an aromatic pentatomic biheterocyclic system, suitable to act as chiral ligands, complexes between said diphosophines and transition metals, and their utilization...
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