Patents in Class 560/16

Matches 1 - 50 out of 337

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Match	Document	Document Title
1	8071807	Antagonists of prostaglandin D2 receptors Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such...
2	7767714	Method of preventing infectious diseases Effective preventive method for infectious diseases, an enhancing method of an infectious disease-preventive action of cystine and composition, food and feed effective for infectious diseases are...
3	7598232	Amino-substituted (E)-2,6-dialkoxystyryl 4-substituted-benzylsulfones for treating proliferative disorders Compounds useful as antiproliferative agents, including, for example, anticancer agents, are provided according to formula (I); wherein: X, X1, X2, Ra, R1, R2,R3, R4, R5, R6, R7, g, M, y, a, b, d,...
4	7566738	Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use Acyloxyalkyl carbamate prodrugs of 3-aminopropylsulfinic acid and analogs thereof, pharmaceutical compositions of 3-aminopropylsulfinic acid and analogs thereof, methods of making prodrugs of...
5	7476754	Biphenyl derived thiamides as calpain inhibitors The present invention relates to compounds derived from biphenyl with activity as calpain inhibitors. One compound of the present invention is a 2,2′-disubstituted biphenyl, where the s...
6	7217831	Insecticide and method of controlling insects An insecticide of formula 1 and the agriculturally acceptable salts thereof, wherein: R1 is selected from the group consisting of:the group OR5 wherein R5 is selected from the group consisting of...
7	7173059	Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same Optically active 3-amino-butene and 1,2-dihydroxy-3-amino-butane intermediate compounds, useful in the synthesis of HIV-protease inhibitors and methods of preparing these intermediate compounds are...
8	7105545	N-p-propargyloxyphenethyl-thioacetic acid amides The invention relates to N-propargyloxy-phenethyl thioacetic acid amide derivatives of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein R1 is...
9	7034015	Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating...
10	6946474	Nitrogen-containing compounds and their use as glycine transport inhibitors The present invention provides trichloroethyl-sulfonylurea-containing compounds that inhibit glycing transporters, pharmaceutical compositions comprising such compounds, methods for using such...
11	6878845	Oligomers from multifunctional acrylates Oligomers from multifunctional acrylates and organonitro compounds are provided. Films obtained from crosslinked oligomers of the present invention are useful as protective or decorative coatings...
12	6838472	Substituted urea retinoid agonists The current invention provide novel compounds, methods of treating or preventing emphysema, cancer and dermatological disorders, pharmaceutical compositions suitable for the treatment or prevention...
13	6803480	Diphenylmethane derivatives The invention relates to novel diphenylmethane derivatives, processes for their preparation and their use in medicaments, in particular for the indications of arteriosclerosis and...
14	6683200	N-substituted-N′-substituted urea derivatives and pharmaceutical compositions containing the derivatives N-Substituted-N′-substituted urea derivatives represented by the following formula, analogs thereof or pharmaceutically acceptable salts thereof are herein provided. These compounds show a TNF-α pr...
15	6559334	Polymers chromatographic separation of enantiomers The invention relates to novel optically active polymerizable dipeptides, to the process for the preparation thereof, to the polymerization thereof and to the use of the polymers as adsorbents for...
16	6534546	Aniline derivatives possessing an inhibitory effect of nitric oxide synthase Compounds represented by the general formula (1): (where R1 is SR6 or NR7R8, where R6 is typically an alkyl group having 1-6 carbon atoms, R7 is a hydrogen atom, an alkyl group having 1-6 carbon a...
17	6472430	Amino thioxomethyl amino oxyacetic acid derivatives Antiatherosclerotic compounds are provided which have the following structure: whereinR is lower alkyl;R1 is hydroxy, amino, or lower alkoxy,R2 and R3 are each independently hydrogen, alkyl or...
18	6444850	Fungicidial compounds having a fluorovinyloxphyenyl moiety and process for the preparation thereof A fungicidal compound of formula (I) having a fluorovinyloxyphenyl moiety and stereoisomers thereof are useful for protecting crops from fungal diseases: wherein:X is CH or N;Y is O or S;Z is O or...
19	6420603	Process for the preparation of n,n'-bis&lsqb 2,3-dihydroxypropyl&rsqb -5-&lsqb (hydroxyacetyl) methylamino&rsqb -2, 4,6-triiodo-1, 3-benzenedi carboxamide A novel process for the preparation of N,N′-bis[2,3-dihydroxypropyl]-5-[(hydroxyacetyl) methylamino]-2,4,6-triiodo-1, 3-benzenedi carboxamide of formula (I), commonly known as lomeprol, a novel n...
20	6407100	Fungicidal aromatic oximes The invention relates to novel compounds of the formula in which R1 is C1-4alkyl and (Y—X) is CH2, C1-2alkylthio-CH═ or C1-2alkyl-ON═ and Z is an aldimino or ketimino group, and to their prepa...
21	6388122	Tryptase inhibitor and novel guanidino derivatives A tryptase inhibitor comprising as an active ingredient at least one member selected from among guanidinoaliphatic acid derivatives of the formula (I), guanidinobenzoic acid derivatives of the...
22	6331627	Intermediates of benzoxazinone derivatives and preparation thereof The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their...
23	6284914	Highly water-soluble metalloproteinase inhibitors New compounds of general formulae (III), (IV) and (V). ##STR1##
24	6265590	Nα-2-(4-nitrophenylsulfonyl)ethoxycarbonyl-amino acids Protected amino acid derivatives of general formula (I) ##STR1##and methods for the prepatation of the derivatives are provided.
25	6265603	Inhibitors of isoprenyl transferase Peptidomimetic isoprenyl transferase inhibitors R6SCHR1'CHR1WCHR2YC(:X)NR3CHR5COR4 wherein R1=OH, H, alkyl, amino group or R1 and R6 together form a heterocyclic ring; R1'=H, alkyl, aryl; R2=H,...
26	6239308	Method for producing α-hydroxy-β-aminocarboxylic acids The present invention provides a simple and inexpensive method for producing α-hydroxy-β-aminocarboxylic acids and their esters.An ester of an N-protected α-amino acid ester is converted into a β-...
27	6235922	Processes and intermediates for preparing benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP Compounds having the following formula I, and pharmaceutically acceptable salts thereof, including dual inhibitors of ACE and NEP and selective ACE inhibitors: ##STR1##wherein: Y1 and Y2 are each...
28	H001950	Processes for preparing indeno[1,2-E][1,3,4]oxadiazine-dicarboxylates Oxadiazines of formula I, wherein R1 is F, Cl or fluoroalkoxy and R2 is alkyl, are prepared by reacting hydrazine derivatives of formula II with a dialkoxymethane in the presence of a protic acid...
29	6166072	Amino acid derivatives Described herein are compounds having the general formula: ##STR1## wherein: Ar1 and Ar2 are independently selected aryl groups, optionally substituted with substituents selected from the group...
30	6153650	Substituted gamma aminobutyric acids as pharmaceutical agents
31	6066754	Process for manufacturing N-alkoxy(or aryloxy)carbonyl isothiocyanate derivatives using N,N-dialkylarylamine as catalyst The present invention provides a process for making N-alkoxy(or aryloxy)carbonyl isothiocyanate derivatives by reacting a chloroformate with a thiocyanate, in the presence of an organic solvent and...
32	6030803	Dibenzodihydropyridinecarboxylic esters and their use in chemiluminescent assay methods
33	6028131	Antioxidants containing phenol groups and aromatic amine groups The invention relates to compounds of the formula I ##STR1## in which R is C1 -C18 alkyl, C5 -C8 cycloalkyl, C7 -C9 phenylalkyl, --CH2 --A--R2 or a group of the formula II, ##STR2## R1 is C1 -C18...
34	6013829	Process for the asymmetric synthesis of S-acyl derivatives of 2-mercaptomethyl -3- phenyl propanoic acid, application to the synthesis of N-(mercaptoacyl) amino acid derivatives Process for the asymmetric synthesis of S-acyl derivatives of 2-mercaptomethyl-3-phenylpropanoic acid of formula (I): characterized in that it comprises the steps consisting in: a) preparing the...
35	5994539	Mercapto acyl aminoacid derivatives endowed with dual ACE-NEP inhibitory activity, useful in the treatment of cardiovascular diseases Compounds of formula ##STR1## wherein R, R1, R2, R3, R4, m and n have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as...
36	5959120	Acetate ester compounds The present invention provides an acetate ester compound of formula (III), ##STR1## a process for synthesizing compound (III), and a process for using that compound to prepare a pyrazolone...
37	5945548	Process for the synthesis of α-substituted acrylic acids and their application Process for the synthesis of α-substituted acrylic acids of general formula (I) and their application to the synthesis of N-(mercaptoacyl)aminoacid derivatives of formula (II). ##STR1##
38	5888972	Peptide compounds, their preparation and uses A compound of the formula: ##STR1## in which R4 is acyl, R5 is lower alkyl, R6 is optionally substituted ar(lower)alkyl or optionally substituted heterocyclic-(lower)alkyl, R7 is lower alkyl or...
39	5866604	Thiol derivatives with metallopeptidase inhibitory activity Compounds of formula (I) wherein R, R1, R2, R3, R4, m and n have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as...
40	5847125	Amino acid derivatives with anticholecystokinin activity Compounds of formula (II) wherein Ar is naphthyl, naphthylmethyl, 1,2,3,4-tetrahydronaphthyl, phenethyl, styryl, indanyl or a substituted derivative of any of the foregoing, or 3,4-dichlorophenyl,...
41	5783735	Process for preparing polymeric amides useful as additives in fuels and lubricating oils A process for preparing polymeric amides is disclosed. The process comprises sequentially reacting a hydrocarbon polymer functionalized (e.g., via the Koch reaction) to contain acid, ester,...
42	5739163	Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists This invention relates to novel compounds containing basic and acidic termini, pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using...
43	5693847	Heteroatom functionalized α-methyl ketones The present invention relates to functionalized ketones and novel processes for synthesizing those ketones. The processes of this invention are especially well suited for synthesizing α-methyl ...
44	5686633	Inks, particularly for ink jet printing Inks, particularly inks for ink jet printing, contain at least one compound of the formula I ##STR1## as a stabilizer. The symbols R1, R2, R3, R4, R3 ' and R4 ' are as defined in claim 1. The...
45	5650428	Arylsulfonamide derivative and pharmaceutical compositions and use thereof An arylsulfonamide derivative of the formula (I): ##STR1## wherein R1 is unsubstituted phenyl or naphthyl, or phenyl substituted by 1 to 3 same or different substituents selected from the group...
46	5637616	Method for treating diseases mediated by proteases A method for the topical or systemic treatment of disorders mediated by proteases which result in skin or mucosal lesions, and in particular, pemphigus, cicatricial pemphigoid, bullous pemphigoid,...
47	5635608	α-carboxy caged compounds The invention relates to caged compounds for the study of biological processes, where the caged compound has a photoremoveable α-carboxy-substituted o-nitrobenzyl group. Covalent attachment of the ...
48	5631405	Method of forming amino acid-derived diaminopropanols useful as chemical intermediates for protease-inhibitors The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs,...
49	5618966	Method forming protease inhibitor synthetic intermediates The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs,...
50	5618775	Mixtures of optically active cyclohexenone oxime ethers, their preparation, intermediates for this purpose and their use as herbicides Mixtures of optically active cyclohexenone oxime ethers having R- and S-configuration in the oxime ether moiety of the formula I ##STR1## (R1 =C1 -C6 -alkyl; ##STR2## X=C1-C4 -alkyl, C1 -C4...

Matches 1 - 50 out of 337

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