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7615669 |
Process for producing fluoro-compounds
The present invention provides a process for producing highly pure fluoro-compounds by making use of N-(2-chloro-1,1,2-trifluoroethyl)diethylamine. The process produces little or no chlorinated...
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7524885 |
Compounds that stimulate glucose utilization and methods of use
The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells:
wherein W, Cyc, p, Y, X, Z, R, R 1 , R 2 , R 3 , R 4 , I, m and n...
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7498459 |
Method for producing (1-alkenyl)cyclopropane compound
A method for producing a (1-alkenyl)cyclopropane compound represented by the formula (2):
wherein R 1 and R 2 are the same or different, and independently represent a hydrogen atom, an...
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7393971 |
Method for producing 3,3-dimethyl-2-(1-propenyl) cyclopropanecarboxylate
A method for producing 3,3-dimethyl-2-(1-propenyl)cyclopropanecarboxylate represented by the formula (2):
wherein R 1 represent an optionally substituted alkyl group, an optionally substituted...
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7390779 |
Cycloalkanecarboxylic acid derivatives as fragants with musk characteristics
Odourant compounds selected from compounds having the structure:
wherein,
R 1 and R 2 may be independently hydrogen or methyl, and n is an integer 1, 2 or 3 provided that n+ the carbon...
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7381833 |
Process for producing 1,2-cis-2-fluorocyclopropane-1-carboxylic ester compound
The present invention provides a for producing 1,2-cis-2-fluorocyclopropane-1-carboxylic ester.
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7365222 |
Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials
Bicyclic cyclopropane derivatives of the general Formula (I)
in which n+m is 0 to 8; r is 1 to 4; R 1 is absent or is a C 1 -C 20 alkylene radical which can be interrupted by O or S, a...
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7276622 |
Method for producing oxygen-containing compound
It is provided that a method for producing an oxygen-containing compound, characterized in that an olefin compound having a carbon-carbon double bond which is bonded to a methyl or methylene group...
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7262320 |
Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives
A process for the production of a 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivative of formula (2):
wherein R is hydrogen, substituted or unsubstituted alkyl, substituted or...
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7253301 |
Optically active copper catalyst composition
There is provided an optically active copper catalyst composition comprising
(a) an optically active salicylideneaminoalcohol represented by the formula (1):
wherein R 1 and R 2 are the...
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7217682 |
Cyclopropanecarboxylic acid esters and pest controllers containing the same
A 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl 2,2-dimethyl-3-(2-cyano-3-hydrocarbyloxy-3-oxo-1-propenyl) cyclopropanecarboxylate given by the formula (1):
wherein G represents C1–C4 alkyl or...
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7199260 |
Process for reductive dehalogenation
A method of producing 2-fluorocyclopropane-1-carboxylic acid ester, which comprise by allowing a compound represented by the following formula (1):
wherein X represents a chlorine atom, a...
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7098245 |
Polynucleotide cleavage agent switched on by photo irradiation
The present invention provides a polynucleotide cleavage agent switched on by photo-irradiation and a method of cleaving or decomposing a polynucleotide such as DNA or RNA using this agent switched...
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7087796 |
Cyclopropanecarboxaldehydes and their use in perfume compositions
The present invention is directed to novel cyclopropanecarboxaldehyde compounds of the general formula
wherein R is a straight, branched, or cyclic hydrocarbon moiety consisting of 1 to 30...
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7084173 |
Compounds that stimulate glucose utilization and methods of use
The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells. The invention also relates to pharmaceutical compositions comprising...
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7009079 |
Chiral copper complex and production processes thereof and using the same
There is disclosed an optically active salicylideneaminoalcohol compound of formula (1):
wherein R 1 represents an alkyl group or the like, R 2 represents
an aryl group and the like,...
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6909014 |
Intermediates for the synthesis of ether compounds
The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias,...
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6909013 |
Process for producing cyclopropanecarboxylates
There is disclosed a process process for producing a cyclopropanecarboxylate of formula (1):
which process comprises reacting cyclopropanecarboxylic acid of formula (2):
with a...
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6908945 |
Ester compound and its use
A cyclopropanecarboxylic acid ester compound of formula (1):
has an excellent pesticidal efficacy, and a pesticidal composition comprising it as an active ingredient is useful for controlling...
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6894195 |
Preparation of 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol
A process for the preparation of 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol comprising hydrogenating 4-methyl-2,3,5,6-tetrafluorobenzonitrile to 4-methyl-2,3,5,6-tetrafluorobenzylamine and...
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6878723 |
LTA4 hydrolase inhibitors
The invention concerns compounds inhibiting LTA 4 hydrolase of formula (I). The invention also concerns their therapeutic, in particular anti-inflammatory, applications.
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6875885 |
Process for the preparation of enantiomerically pure pyrethroid insecticides
A process for producing compounds of formula (VIIa) and (VIIb) wherein X is a leaving group; Y and Y 1 are idependently Cl or Br; and Z is Cl, Br or a haloalkyl group which process comprises a)...
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6858650 |
Stable salts of novel derivatives of 3,3-diphenylpropylamines
The present invention concerns highly pure, crystalline, stable compounds of novel derivatives of 3,3-diphenylpropylamines in the form of their salts, a method for the manufacture and highly pure,...
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6770676 |
Dicarboxylic acid derivatives
The present invention relates to 2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives represented by the formula: the pharmaceutically acceptable salts thereof, or the hydrates...
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6753443 |
Preparing method of chiral ester
The present invention relates to a process for preparing a chiral ester according to the formula (100): by reacting (i) a racemic alcohol, (ii) a selected ruthenium complex to activate...
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6750363 |
Olefination process to itaconate and succinate derivatives
An efficient and selective process, capable of scale-up, to make itaconate derivatives of formula (IV), and/or succinate derivatives of formula (V) and/or (VI) by asymmetric hydrogenation of the...
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6734320 |
Non-symmetric, partially fluorinated lubricant additives
Novel non-symmetric, partially fluorinated compositions and method of manufacture which are useful as lubricants or as additives to lubricant formulations involving the molecular structure: R 1f...
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6730804 |
Process for preparing cyclopropanecarboxylates of lower alcohols
Cyclopropanecarboxylates of lower alcohols are prepared by esterification of the corresponding cyclopropanecarboxylic acids with the corresponding lower alcohols in the presence of an acid...
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6706910 |
Method for producing cyclopropanecarboxylates
There is provided a method for producing a cyclopropanecarboxylate of formula (1): which comprises contacting a cyclopropanecarboxylate of formula (2): with a monohydroxy compound of formula...
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6642418 |
Processes for preparing intermediates
The invention relates to processes for the preparation of compounds of formula (I), wherein R 1 and R 2 are as defined in the description.
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6635784 |
Process for the preparation of enantiomerically-enriched cyclopropylalanine derivates
Disclosed are processes for the preparation of enantiomerically-enriched cyclopropylalanine derivatives by the hydrogenation of certain enamides in the presence of a catalyst comprising a...
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6613935 |
Process for producing 1-acyl-1-cyclopropanecarboxylate derivatives
A process includes allowing a β-ketoester derivative represented by following Formula (1): wherein R 1 is a hydrogen atom or a hydrocarbon group; and R 2 is a hydrocarbon group, to react with...
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6552217 |
Process for the preparation of alkyl 1-methylcyclopropanecarboxylate
Disclosed is a 4-step process for the preparation of alkyl esters of 1-methylcyclopropanecarboxylic acid which comprises the steps of (1) converting γ-butyrolactone to α-methyl-γ-butyrolactone;...
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6531626 |
Method for producing cyclopropanecarboxylates
There is disclosed a method for producing cyclopropanecarboxylates of the formula (3): by transesterification in the presence of a lanthanoid metal alkoxide
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6498267 |
5-halo-4-fluoro-4,7,7-trimethyl-3-oxabicyclo&lsqb 4.1.0&rsqb heptan-2-ones, process for their preparation and their use for preparing cyclopropanecarboxylic acids
5-Halo-4-fluoro-4,7,7-trimethyl-3-oxabicyclo[4.1.0]heptan-2-
ones, process for their preparation and their use for preparing cyclopropanecarboxylic acids Compounds of the formula (I), in which...
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6469198 |
Chiral copper complex catalyst composition and asymmetric production process using the same
There is disclosed chiral copper complex catalyst composition, which is obtained by contacting an optically active N-salicylideneaminoalcohol compound of formula (1): with a mono-valent or...
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6462225 |
Method for producing 2,2-dimethyl-3-(1-propenyl)cyclopropanecarboxylate ester
An ester compound, which is a production intermediate of a pyrethroid compound, given by formula wherein R 1 represents C 1-6 alkyl group, etc., can be produced by allowing to react an...
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6462224 |
Process for the preparation of 1,1-cyclopropanedicarboxylic diesters
1,1-cyclopropanedicarboxylic diesters are prepared from malonic diesters, 1,2-dihaloethane and alkali metal carbonate in the presence of a mixture of available or in situ-produced phase transfer...
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6448412 |
Methods for the preparation and characterization of multi-substituted fullerenes
The invention is directed to multiply-substituted fullerene derivatives of novel configurations, and methods for their preparation and use. The methods involve the combinatorial synthesis of a...
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6441220 |
Methods for producing cyclopropane carboxylates
There is provided a method for producing a cyclopropanecarboxylate of formula ( 3 ): wherein R 1 , R 2 , R 3 , R 4 and R 5 each independently represent: a hydrogen atom, halogen atom, an...
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6441176 |
Method for preparing sodium-hydrogen exchanger type 1 inhibitor
Methods of preparing NHE-1 disclosed. The NHE-1 inhibitors are useful for the reduction of tissue damage resulting from tissue ischemia.
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6423865 |
Compounds and their application as well as a method of producing liquid crystalline polymers therefrom
The invention relates to compounds with the general formula Y 1 —A 1 —M 1 —A 2 —Y 2 wherein Y 1 and Y 2 are different from each other and Y 1 is an acrylate or methacrylate residue and...
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6417389 |
Process for the preparation of HPB esters
This invention relates to a novel advantageous process for the stereoselective preparation of 2-hydroxy-4-phenylbutyrates (HPB esters) and of their precursors. This is done by starting from readily...
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6414181 |
Process of producing cyclopropanecarboxylate compounds
Provided are processes of producing a cyclopropanecarboxylate compound of Formula (I): The processes comprise reacting a cyclopropanecarbaldehyde compound of Formula (II): with a dicarboxylate...
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6403638 |
2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors
Compounds having the formulas below, where R is H, lower alkyl, or a pharmaceutically acceptable salt, and where R 1 represents i-propyl, t-butyl or n-butyl groups, have selective RXR retionoid...
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6399785 |
Multiply-substituted fullerenes
The invention is directed to multiply-substituted fullerene derivatives of novel configurations, and methods for their preparation and use. The methods involve the combinatorial synthesis of a...
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6376699 |
Process for preparing alkoxytriazolinones
Hydroazinecarboxylic acid ester of the formula In which R 1 is an optionally substituted alkyl group, an aryl group, an arylalkyl group or a cycloalkyl group, and R 3 is an optionally...
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6369194 |
Vicinyl tricarbonyl compounds and combinatorial libraries containing same
The invention relates to compounds of formula where R is a structural diversity element selected from the group consisting of alkyl, cycloalkyl, aryl, heteroaryl, peptidyl,...
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6359164 |
Process for the preparation of cyclopropylacetylene
The present invention relates generally to novel methods for the preparation of cyclopropylacetylene which is an essential reagent in the asymmetric synthesis of...
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6297410 |
Process for the preparation of cyclopropylacetylene
The present invention relates generally to novel methods for the synthesis of cyclopropylacetylene which is an essential reagent in the asymmetric synthesis of...
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