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8148568 |
Esters of (2-hydroxy-3-oxo-cyclopent-1-enyl) acetic acid and their use for preparing (−)-R-homocitric acid gamma-lactone, (+)-S-homocitric acid gamma-lactone and the corresponding (−)-R-homocitric acid and (+)-S-homocitric acid salts
Archiral (2-hydroxy-3-oxo-cyclopent-1-enyl) acetic acid) alkyl, alkylphenyl and phenyl esters, and a simple and efficient method for the synthesis of both enantiomers of homocitric acid...
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8092720 |
Polymer-supported metal complex catalyst
Polymer supported metal complex catalysts and methods of their preparation and use are described. The polymer supported metal complex catalysts can be obtained via ligand exchange reactions between...
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8063240 |
Prostaglandin E1 and E2 analogs for the treatment of various medical conditions
A prostaglandin analog with selectivity to EP receptors and demonstrating EP agonist activity that may be used to expand hematopoietic stem cell populations or to treat or prevent influenza, bone...
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8030514 |
Processes and intermediates for the preparations of prostaglandins
The present invention provides novel processes for the preparation of a cyclopentanone of Formula II and a lactone of Formula I, which are useful in the production of prostaglandins: wherein Z, R2,...
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7981968 |
Photoresponsive polymer, built-up type diacetylene polymer, crystal of ammonium carboxylate, and method of manufacturing them
A crystal of carboxyl acid and at least one compound selected from the group consisting of amine and ammonia are mixed in an absence of a liquid medium. The carboxyl acid is conjugated diene such...
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7897802 |
Process for production of substituted cyclopentanone
A substituted cyclopentanone represented by the following formula (2): (wherein R3 and R4 represent a substituent having 1 to 8 carbon atoms, may be the same as R1 and R2, respectively, and may be...
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7875688 |
Free-radical curable polyesters and methods for use thereof
The invention is based on the discovery that certain polyester compounds bearing are useful as b-stageable and/or liquid adhesives for the microelectronic packaging industry.
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7868113 |
Low shrinkage polyester thermosetting resins
The invention is based on the discovery that a certain polyester compounds are useful as b-stageable adhesives for the microelectonic packaging industry. The polyester compounds described herein...
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7786234 |
Free-radical curable polyesters and methods for use thereof
The invention is based on the discovery that certain polyester compounds bearing free-radical curable moieties are useful as b-stageable adhesives for the microelectronic packaging industry.
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7776912 |
Acetals of nepetalic acid and method of preparation
Disclosed are acetals of nepetalic acid. They may be prepared by reaction of an alcohol with nepetalic acid, and are useful as repellents for insects and arthropods, in addition to other uses.
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7750084 |
Photoresponsive polymer, built-up type diacetylene polymer, crystal of ammonium carboxylate, and method for manufacturing them
A crystal of carboxyl acid and at least one compound selected from the group consisting of amine and ammonia are mixed in an absence of a liquid medium. The carboxyl acid is conjugated diene such...
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7737182 |
Pharmaceuticals for xerosis
A method for or treating xerosis by applying a prostaglandin D receptor selective agonist to a mammal.
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7737140 |
Therapeutic compounds
Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein J1, J2, U1, B, Y, and A are as described. Methods, compositions, and medicaments related...
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7718701 |
Antipruritic agent
A method of treating atopy-evoked pruritic symptoms by administering a prostaglandin derivative.
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7713968 |
Substituted arylcyclopentenes as therapeutic agents
Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein Y, A, and B are as described. Methods, compositions, and medicaments related thereto are also...
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7696347 |
Oxymethyl boron compounds
The present invention provides compounds which are useful as safe substitutes for the organotin reagent used in coupling reaction for the oxymethylation of aromatic rings, such as alkoxymethylation...
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7674827 |
Indanyl- and tetrahydronaphtyl-amino-thiourea compounds for combating animal pests
Indanyl- and Tetrahydronaphtyl-amino-thiourea compounds for combating animal pests The present invention relates to Indanyl- and Tetrahydronaphtyl-amino-thiourea compounds of formula I wherein the...
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7649107 |
Process for the preparation of cyclopentanone derivatives
The present invention relates to the field of organic synthesis and more particularly to a new process for the preparation of an acetal derivative of an alkyl...
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7498458 |
Process for the preparation of prostaglandins and analogues thereof
Disclosed are processes for the synthesis and purification of prostaglandins and analogues thereof, especially analogues of PGF2α.
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7442827 |
Process for Producing Cyclopentanone-2, 3, 5-Tricarboxylic Acid Triester
The present invention provide a process that allows the industrially advantageous production of a cyclopentanone-2,3,5-tricarboxylic acid triester. Namely, the present invention provides a process...
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7390779 |
Cycloalkanecarboxylic acid derivatives as fragants with musk characteristics
Odourant compounds selected from compounds having the structure: wherein, R1 and R2 may be independently hydrogen or methyl, and n is an integer 1, 2 or 3 provided that n+ the carbon atoms in R1...
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7388103 |
Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof
The present invention discloses cyclopentane carboxylate compounds. The 1-hydrocarbyl-2-acyloxy-cyclopentane carboxylates according to the invention have a general formula (I): wherein groups R1,...
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7285613 |
Free-radical curable polyesters and methods for use thereof
The invention is based on the discovery that certain polyester compounds bearing free-radical curable moieties are useful as b-stageable adhesives for the microelectonic packaging industry.
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7253300 |
Production process for high purity tricyclo-[5.2.1.02,6]decane-2-carboxylic acid ester
In a process for producing tricyclo[5.2.1.02,6]decane-2-carboxylic acid ester by reacting tricyclo[5.2.1.02,6]deca-3-ene with carbon monoxide and alcohol in the presence of HF, carried out...
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7227044 |
Cycloalkanone composition
The present invention relates to a cycloalkanone composition which contains cycloalkanone (1) in an amount of 70 wt % or more based on the composition, wherein the content of a dimer of a...
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7166750 |
Process for the preparation of 5-[(4-chlorophenyl)methyl]-2,2-dimethylcyclopentanone
5-[(4-chlorophenyl)methyl]-2,2-dimethylcyclopentanone is produced by reacting 1-[(4-chlorophenyl)methyl]-3-methyl-2-oxocyclopentanecarboxy
lic acid methyl ester or...
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7132564 |
Process for preparing cyclic ketones
The present invention provides a process for preparing cyclic 1,3-keto esters in the absence of solvent, using solid-state or high viscosity reactors.
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7122678 |
Cyclic amino acids and derivatives thereof useful as pharmaceutical agents
The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain,...
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7078559 |
Method of producing acetate derivative
The present invention relates to a method of producing an acetate derivative represented by the formula (II) by demonocarboxylating dimalonate represented by the formula (I), wherein water is...
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7060840 |
Catalytic asymmetric desymmetrization of prochiral compounds
The present invention relates to methods for the synthesis of chiral non-racemic products, e.g., enantiomerically-enriched hemiesters, from prochiral starting materials, e.g., meso anhydrides. The...
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7057077 |
Method for producing 2- (alkyl) cycloalkenone
A method for producing 2-(alkyl)cycloalkenone and a method for producing alkyl(3-oxo-2-alkylcycloalkyl) acetate and 5-alkyl-5-alkanolide which are useful as flavoring materials and physiologically...
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7045653 |
Pharmaceuticals
The invention relates to NEP inhibitors for treating cardiovascular disorders. Preferred NEP inhibitors are compounds of formula (I) wherein R1 is C1–C6alkyl, C1–C6alkoxyC1–C3alkyl or C1–C6...
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7038060 |
Synthesis of 2-butyl-3-(2′-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspiro[4.4]-non-ene-4-one
Provided is a novel method of making 2-butyl-3-[[2′(1-trityl-1H-tetrazol-5-yl)biphen-4-yl]methy
l]-1,3-diazaspiro[4.4]non-1-ene-4-one, which can be converted to irbesartan. Also provided are m...
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7022678 |
Pregabalin lactose conjugates
In accordance with the present invention, there is provided pregabalin lactose conjugate compounds. Also provided as part of the present invention is a novel method of central nervous system...
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6909014 |
Intermediates for the synthesis of ether compounds
The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias,...
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6858650 |
Stable salts of novel derivatives of 3,3-diphenylpropylamines
The present invention concerns highly pure, crystalline, stable compounds of novel derivatives of 3,3-diphenylpropylamines in the form of their salts, a method for the manufacture and highly pure,...
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6825375 |
Intermediate and process for producing fluorinated carboxylic acid derivative from the same
The present invention relates to a 2-fluoro-2-(3-oxobicyclopentyl)acetate derivative represented by the formula (1): The compound according to the present invention is useful for efficient...
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6770676 |
Dicarboxylic acid derivatives
The present invention relates to 2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives represented by the formula: the pharmaceutically acceptable salts thereof, or the hydrates...
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6734320 |
Non-symmetric, partially fluorinated lubricant additives
Novel non-symmetric, partially fluorinated compositions and method of manufacture which are useful as lubricants or as additives to lubricant formulations involving the molecular structure:...
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6596898 |
Process for preparing halogenated cyclopropane derivatives
A process for preparing compounds represented by the following general formula (I) wherein X represents chlorine atom, bromine atom, or iodine atom, and R includes alkoxy group and amino group...
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6593489 |
Substituted cyclopentenes, their preparation and their use for chiral scaffolds
3,4-Disubstituted-1-cyclopentene compounds, in substantially enantiopure form, have the relative stereochemistry according to formula (1A) or (1B) including the opposite enantiomers thereof,...
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6576786 |
Process for preparing substituted cyclopentane derivatives and novel crystalline structures thereof
The invention relates to a process for preparing substituted cyclopentane derivatives represented by the formula (I) wherein R1, R2, R3, R4, X and Y are as described in the specification, and...
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6562861 |
Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors
Compounds I-III wherein U is CH, O, or S; Z is mono- or di-substituted carbon; R is (CH2)nCO2H, (CH2)nSO3H, (CH2)nPO3H2, (CH2)nNO2, CH(SCH3)3, esters; R1 is H, hydroxyalkyl, aminoalkyl,...
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6518305 |
Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases
Disclosed are compounds of the formula: which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and...
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6503745 |
Cyclopentane and cyclopentene compounds and use for detecting influenza virus
New cyclopentane and cyclopentene compounds are provided along with their use in method for detecting influenza virus.
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6500990 |
Method for producing jasmonate derivatives and intermediates thereof
A process for efficiently producing a 2-alkyl-2-cyclopentenone comprising reacting an amine and a hydrogen halide, which are present in a ratio ranging from 1.1:1 to 5:1, with a 2-alkylidene...
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6495711 |
Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters
The invention relates to a process for preparing (−)-(1S,4R) N protected 4-amino-2-cylcopentene-1-carboxylate esters represented by the formula (I) wherein R1 and R2 are as described within the s...
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6458569 |
Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, novel jasmonic acid isomer produced thereby and uses thereof
Described is a bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, as well as a novel jasmonic acid isomer produced thereby and organoleptic uses...
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6452010 |
Process for the preparation of hydroxamic acid derivatives
The present invention provides an improved process for preparing an hydroxycarbamoyl derivative of a carboxylic acid using a hydroxylammonium salt of a carboxylic acid as a reagent.
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6423865 |
Compounds and their application as well as a method of producing liquid crystalline polymers therefrom
The invention relates to compounds with the general formula Y1—A1—M1—A2—Y2 wherein Y1 and Y2 are different from each other and Y1 is an acrylate or methacrylate residue and Y2 is a vinyl ether, ...
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