Patents in Class 560/12

Matches 1 - 50 out of 557

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Match	Document	Document Title
1	8071807	Antagonists of prostaglandin D2 receptors Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such...
2	8003083	Benzylidene malonamide and salt thereof, ultraviolet ray absorbent, and agent for external application to the skin The present invention is benzilidene malonamide represented by the following formula (1) and salts thereof, an ultraviolet absorbent consisting of said new compound, and an external preparation...
3	7968597	Levodopa prodrug mesylate, compositions thereof, and uses thereof (2R)-2-Phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and crystalline form thereof, methods of making the same, pharmaceutical compositions thereof, and methods of...
4	7931946	Liquid crystal compound containing sulfone group, liquid crystal composition comprising the same, and optical film using the same liquid crystal composition Disclosed are a novel liquid crystal compound containing a sulfone group, a liquid crystal composition comprising the same, and an optical film using the same liquid crystal composition. More...
5	7932326	Chelating compounds and immobilized tethered chelators Novel di- and tripodal compounds useful as chelators, intermediates for their production and a method for treating an aqueous solution to remove trivalent metal ions are presented.
6	7893270	Process for the production of cyclic diketones The present invention relates to a process for the preparation of compounds of formula (I), wherein the substituents are as defined in claim 1, by reacting a compound of formula (II), with a...
7	7884103	N-sulfonyl-α-amino-acid derivatives The invention relates to N-sulfonyl-α-amino-acetic acid derivatives of the general formula (I): including the optical isomers thereof and mixtures of such isomers, wherein Ar1 and Ar2 ...
8	7683185	Histone deacetylase inhibitors The present invention provides histone deacetylase inhibitors of general formula (I), process for the preparation of such compounds and uses of the compounds in medicine.
9	7638556	Freeze-dried product of N-[o-(p-pivaloyloxy benzenesulfonylamino)benzoyl]glycine monosodium salt tetra-hydrate and a process for the manufacture thereof A method for the preparation of a freeze-dried product of N-[o-(p-pivaloyloxybenzenesulfonylamino)benzoyl]glycine monosodium salt tetra-hydrate dissolved in a mixed solvent of water and ethanol,...
10	7576234	Synthesis of 2-alkyl amino acids Non-natural amino acids such as 2-alkylated amino acids allow for the synthesis of a wider variety of peptidal and non-peptidal pharmaceutically active agents. A method of preparing a 2-alkyl amino...
11	7528276	Process for preparing the intermediate compounds for PPAR α ligands The present invention provides a process for preparing the compounds of formula (II) according to a single reaction, which is an important intermediate compound for synthesizing GW7647 (III) and...
12	7504431	Sulfonyl amide inhibitors of calcium channel function Compounds of formula I its stereoisomers, solvates, and salts, thereof, wherein: a, b, c, d, f, n, m and Ra are defined herein are are inhibitors of calcium channel function, and are useful in...
13	7498358	Human ADAM-10 inhibitors The present invention provides compounds useful for inhibiting the ADAM-10 protein. Such compounds are useful in the in vitro study of the role of ADAM-10 (and its inhibition) in biological...
14	7488844	Therapeutic agents The present invention provides a compound of formula I processes for preparing such compounds, their the utility in treating clinical conditions including lipid disorders (dyslipidemias) whether or...
15	7456249	Catalyst, its preparation and the polymerization of cyclic ethers over this catalyst The present invention relates to a solid, acid catalyst for the preparation of polytetrahydrofuran, polytetrahydrofuran copolymers, diesters or monoesters of these polymers by polymerization of...
16	7453010	Phenylcyclohexylpropanolamine derivatives, preparation and therapeutic application thereof The invention relates to compounds of general formula (I): where R1 represents H or a (C1-C4)alkyl, —CO(C1-C4)alkyl, (C1-C4)alkylphenyl or —CO-phenyl group, said phenyl optionally being sub...
17	7417059	Substituted aromatic-ring compounds, process for producing the same and use The present invention is directed to a class of cyclohexene derivatives bearing sulfamoyl and ester groups which have an inhibitory activity on nitric oxide (NO) production and cytokine production,...
18	7351825	Cyclopropane compounds and pharmaceutical use thereof The present invention provides a compound having aggrecanase inhibitory activity and MMP-13 inhibitory activity, and useful as a therapeutic agent for osteoarthritis, rheumatoid arthritis and the...
19	7312177	Thermosensitive recording materials A thermosensitive recording material comprising a substrate sheet and a thermosensitive colored image-forming layer formed on at least one surface of the substrate sheet and comprising at least one...
20	7262317	Freeze-dried preparation of n[o-(p-pivaloyloxybenzenasulfonylamino) benzoyl] glycine monosodium salt tetrahydrate and process for producing same A method for the preparation of a freeze-dried product of N-[o-(p-pivaloyloxybenzenesulfonylamino)benzoyl]glycine monosodium salt tetra-hydrate dissolved in a mixed solvent of water and ethanol,...
21	7244845	Process for preparing cyclic N-substituted alpha-imino carboxylic acids The present invention relates to the novel methods of making matrix metalloproteinase inhibitors of Formula (I):
22	7230031	Thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof The present invention provides a compound represented by general formula (I): or pharmaceutically acceptable salts thereof, wherein W is O, S(O)m, CH2 and the like; R1 is halogen, lower alkyl,...
23	7199265	Thyroid receptor ligands, pharmaceutical compositions comprising them and their use in the treatment of disorders influenced by thyroid hormones This invention relates to compounds of the formula (I) which are thyroid receptor ligands, and are preferably selective for the thyroid hormone receptor β, to methods of preparing such compounds ...
24	7094919	Preparation of substituted aromatic carboxylic acid esters Methods for preparing substituted aromatic carboxylic acid esters are described. In particular, the invention relates a method for preparing a nitro-substituted aromatic carboxylic acid ester:...
25	7084178	Antiamyloid phenylsulfonamides: N-cycloalkylcarboxamides derivatives A series of N-cycloalkylcarboxamide derivatives of N-benzyl benzenesulfonamides of Formula I are described. The compounds inhibit β-amyloid peptide (β-AP) production and are useful in the t...
26	7034045	Monofluoroalkyl derivatives The present invention provides certain monofluoroalkyl derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions,...
27	7034015	Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating...
28	6982344	Process for preparation of optically active sulfonamides and intermediates for their synthesis A method including resolution of a diastereomeric mixture represented by the formula wherein R1 and R2 are the same or different and each is an optionally substituted hydrocarbon group or an...
29	6936719	Biaryl compounds as serine protease inhibitors Compounds of formula (I) are useful as inhibitors of trypsin like serine protease enzymes such as thrombin, factor VIIa, factor Xa, TF/FVIIa, and trypsin. These compounds could be useful to treat...
30	6884821	Carboxylic acid derivatives and drugs containing the same Novel carboxylic acid derivatives of general formula (I), salts of the same, esters thereof, or hydrates of them, which are useful as insulin resistance improvers; and drugs containing the...
31	6818765	Benzene-sulphonamide derivatives and their uses Benzene-sulphonamide derivatives complying with the general formula (I): in which the different symbols have different meanings, their optical isomers and the salts pharmacologically acceptable of...
32	6815556	Compounds having fungicidal activity and processes to make and use same A compound according to formula one that is useful as a fungicide is provided. Additionally, processes to make and use same are provided.
33	6686494	Synthesis of S-alkyl and S-aryl thiocarbamates, one-pot two-step general synthesis A method for preparing S-alkyl and S-aryl thiocarbamates comprising reacting a precursor thiol reagent with trichloroacetyl chloride to produce an S-alkyl and S-aryl trichloroacetyl thioester...
34	6677472	Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same A thermosensitive recording material having high whiteness and resistance to color formation under high temperature, high humidity conditions has a thermosensitive colored image-forming layer...
35	6649656	Anthranilic acid derivatives The present invention relates to an anthranilic acid derivative expressed by the following formula (1) or the following formula (2), or its pharmacologically permissible salt or solvate.
36	6613937	S-nitroso- and S-nitro-N-acyl-L-cysteine ester derivatives as pharmalogically active agents and pharmaceutical compositions containing said compounds SNACE derivatives as pharmacological active agents and pharmacological compositions containing these compounds, in particular for transdermal, oral, rectal and inhalational application, are described.
37	6590119	Methods for the synthesis of dioxoalkanoic acid compounds The invention relates to improved methods of producing aryl dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents by the alcoholysis of...
38	6573387	Synthesis of α,β-substituted amino amides, esters, and acids α,β-Unsaturated amides and esters are converted to α,β-substituted amino amides, esters, and acids. An α,βunsaturated amide or ester is first converted to an α,β-hydroxysulfonamide or hydroxy...
39	6552061	Amino acid derivatives and anti-inflammatory agents Provided are an anti-inflammatory agent containing, as an active ingredient, at least one selected from amino acid derivatives represented by formula (I) wherein Ar represents an optionally...
40	6541422	Method for improving the selectivity of 1,3-cyclohexanedione herbicide A method of selectively controlling undesirable vegetation in crops by using a postemergent application of an herbicidally effective amount of a metal chelate of a 2-(substituted...
41	6506764	Hydroxamic and carboxylic acid derivatives Compounds of the formula B—X—(CH2)m—CR1R2—(CH2)n—CO—Y (I)have therapeutic utility as inhibitors of metalloproteinases etc.
42	6506944	Preparation of substituted olefins C6 compounds of the formula (I) E—CH2—CH═CH—CH2—E1 (I)are prepared by self metathesis or cross metathesis of compounds of the formulae (II) and/or (III)R—CH═CH—CH2—E (II)R1—CH═CH—CH2—...
43	6498190	Bicyclic amino derivatives and PGD2 antagonist containing the same A compound of the formula (I): wherein for example, a compound below: whereinR1 is CH3, H or Na; and X1—X2—X3 is or its salt or a hydrate thereof is useful as PGD2 antagonist and can be used as a d...
44	6495604	Cycloalkene derivatives, process for producing the same, and use The present invention provides a compound represented by the formula: wherein R represents an aliphatic hydrocarbon group optionally having substituents, an aromatic hydrocarbon group optionally...
45	6458948	Process for producing carboxylic acid derivative and condensing agent comprising quaternary ammonium salt A method of preparing carboxylic acid derivatives comprising mixing a quaternary ammonium salt having a particular triazine ring in the molecules thereof, a carboxylic acid compound and a compound...
46	6455711	Method for producing polytetrahydrofuran A process for preparing polytetrahydrofuran, polytetrahydrofuran copolymers or diesters or monoesters of these polymers comprises polymerizing tetrahydrofuran in the presence of at least one...
47	6403644	Method of treating disease with sulfonylamino acid derivatives The present invention is related to: (i) matrix metalloproteinase inhibitors containing sulfonylamino acid derivatives of the formula (Ia); wherein R1 is hydrogen, C1-4 alkyl; R2 is hydrogen, C1-8...
48	6388122	Tryptase inhibitor and novel guanidino derivatives A tryptase inhibitor comprising as an active ingredient at least one member selected from among guanidinoaliphatic acid derivatives of the formula (I), guanidinobenzoic acid derivatives of the...
49	6384072	Benzocycloheptene derivatives This invention relates to benzocycloheptene derivatives having novel structure. More particularly, it relates to new benzocycloheptene derivatives and pharmaceutically acceptable salts thereof,...
50	6350905	Aminohydroxylation of Olefins Osmium-catalyzed aminohydroxylation reactions are accelerated and expanded in scope by the use of olefinic substrates having ionic groups, either anionic or cationic. The use of ionic groups on...

Matches 1 - 50 out of 557

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