Patents in Class 560/10

Matches 1 - 50 out of 363

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Match	Document	Document Title
1	8163806	Controlled release of biologically active compounds from multi-armed oligomers The present invention relates to the discovery of biodegradable multi-armed oligomers wherein the end groups of these oligomers have been functionalized with biologically active molecules. The...
2	8066906	Polymerizable compound and polymerizable composition A polymerizable compound represented by general formula (1): wherein A represents a ring assembly composed of at least two 6-membered rings each optionally having a substituent; X1 and X2 each...
3	8008297	Lysine based compounds The present invention provides lysine based compounds of the formula; and when the compound of formula I comprises an amino group, pharmaceutically acceptable ammonium salts thereof, wherein R1 may...
4	7538165	Conductive polyaniline composition, film thereof and processes for producing these The invention provides an electrically conductive polyaniline composition comprising polyaniline which contains at least one of novolac resins selected from the group consisting of phenolsulfonic...
5	7446222	Phenyl compounds Compounds of formula (I) or derivatives thereof: wherein A, B, Z, R1, R2a, R2b, Rx, R8, and R9 are as defined in the specification, a process for the preparation of such compounds, pharmaceutical...
6	7388008	Lysine based compounds The present invention provides lysine based compounds of the formula; and when the compound of formula I comprises an amino group, pharmaceutically acceptable ammonium salts thereof, wherein R1 may...
7	7365196	Sulphonamido-substituted bridged bicycloalkyl derivatives A class of compounds is disclosed, comprising sulphonamido-substituted bridged bicycloalkyl structures. The compounds are inhibitors of gamma-secretase, and hence are useful in the treatment of...
8	7217831	Insecticide and method of controlling insects An insecticide of formula 1 and the agriculturally acceptable salts thereof, wherein: R1 is selected from the group consisting of:the group OR5 wherein R5 is selected from the group consisting of...
9	7199265	Thyroid receptor ligands, pharmaceutical compositions comprising them and their use in the treatment of disorders influenced by thyroid hormones This invention relates to compounds of the formula (I) which are thyroid receptor ligands, and are preferably selective for the thyroid hormone receptor β, to methods of preparing such compounds ...
10	6936636	5-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity Compounds of the formula: where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects of...
11	6906046	Pharmaceutical uses and synthesis of benzobicyclooctanes Benzobicyclooctane compounds, their use in inhibiting cellular events involving TNF-α and IL-8, and in the treatment of inflammation events in general; a combinatorial library of diverse ...
12	6875895	Bis (diphenylvinyl) arene compound Provided is a bis(diphenylvinyl)arene compound having a reactive functional group on phenyl group, represented by below formula (1), wherein, Ar is an arylene group and has one or more...
13	6846890	Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization A novel norbornene derivative represented by a general formula (1m) shown below is provided. By conducting a ring opening polymerization of this norbornene derivative, or by performing a subsequent...
14	6747148	Sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion Sulfonamide derivatives, their physiologically tolerable salts and their prodrugs according to the present invention are vitronectin receptor antagonists and inhibitors of cell adhesion, as well as...
15	6632816	Aromatic derivatives as HIV aspartyl protease inhibitors The present invention provides HIV aspartyl protease inhibitors of the formula; and when the compound of formula I comprises an amino group, pharmaceutically acceptable ammonium salts thereof,...
16	6603012	RAR selective retinoid agonists New compounds containing bicyclic fused rings, one of which being a phenyl moiety connected by an aliphatic chain to a cycloalkyl or aryl moiety, and pharmaceutically active salts thereof are...
17	6326510	Bi-aromatic compounds, compositions containing them and uses The invention relates to novel biaromatic compounds having general formula I ##STR1##and their use in pharmaceutical compositions for use in human and veterinary medicine, in particular for...
18	6291702	Azulenyl nitrone spin trapping agents, methods of making and using same The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones...
19	6277845	Hydrazono-benzazulene derivatives, pharmaceutical compositions and intermediates Compounds of the formula ##STR1##wherein the substituents are as defined in the application and their pharmaceutically acceptable acid and base salts thereof which are useful for preventing loss of...
20	6265603	Inhibitors of isoprenyl transferase Peptidomimetic isoprenyl transferase inhibitors R6SCHR1'CHR1WCHR2YC(:X)NR3CHR5COR4 wherein R1=OH, H, alkyl, amino group or R1 and R6 together form a heterocyclic ring; R1'=H, alkyl, aryl; R2=H,...
21	6258977	Alkyl3-oxoalkanoates An alkyl 3-oxoalkanoate, a process for preparation and use for the synthesis of fatty hydroxylated amino acids, fatty amino alcohols and ceramides.
22	6201019	Bi-aromatic compounds bound by a heteroethynylene radical and pharmaceutical and cosmetic compositions containing same Bi-aromatic compounds linked via a heteroethynylene radical are provided along with pharmaceutical and cosmetic compositions containing these compounds and methods for their use.
23	H001950	Processes for preparing indeno[1,2-E][1,3,4]oxadiazine-dicarboxylates Oxadiazines of formula I, wherein R1 is F, Cl or fluoroalkoxy and R2 is alkyl, are prepared by reacting hydrazine derivatives of formula II with a dialkoxymethane in the presence of a protic acid...
24	6166072	Amino acid derivatives Described herein are compounds having the general formula: ##STR1## wherein: Ar1 and Ar2 are independently selected aryl groups, optionally substituted with substituents selected from the group...
25	6110955	Metabolically stabilized oxyalkylene esters and uses thereof This invention relates to compositions for and methods of treating, preventing or ameliorating cancer and other proliferative diseases as well as methods of inducing wound healing, treating...
26	6018068	Naphthyloxyacetic acid derivatives and drugs comprising the same as active ingredients The naphthyloxyacetic acid derivatives of the formula (I) ##STR1## wherein A is H, --(alkylene)COOR1, --(alkylene)CONR2 R, --(alkylene)OH, --(alkylene)tetrazole, --(alkylene)CN; E is single bond or...
27	5945561	Retinoid-like compounds Certain novel substituted (5,6)-dihydroanthracenyl compounds of the general formula ##STR1## wherein A, n, p, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined in the specification exhibit...
28	5889053	Farnesyl transferase inhibitors, preparation thereof and pharmaceuticals compositions containing said inhibitors Novel farnesyl transferase inhibitors of general formula (I), ##STR1## the preparation thereof and pharmaceutical compositions containing said inhibitors, are disclosed. In general formula (I), R1...
29	5866604	Thiol derivatives with metallopeptidase inhibitory activity Compounds of formula (I) wherein R, R1, R2, R3, R4, m and n have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as...
30	5849793	HIV matrix protein tyrosine position 29 pocket binders There is disclosed a structural genus of compounds, defined according to coordinates in three-dimensional space, that binds amino moieties on neighboring lysine residues in a tyrosine residue 29...
31	5843999	2-phenylazulene derivatives and a manufacturing method of these compounds A series of new azulene derivatives are disclosed, which are represented by the following formula; ##STR1## wherein: R1 is hydrogen atom, lower alkoxycarbonyl group, carboxy group, halogen atom,...
32	5843910	Colchicine derivatives and the therapeutical use thereof The present invention relates to novel colchicine derivatives of formula (1), where Y is a --CH2 --CH--NH--R3 group or a --CH--CH2 OR3 group and the other variables are as defined in claim 1,...
33	5837807	Tetrahydronaphthalene compounds This invention is directed to tetrahydronaphthalene compounds of the formula ##STR1## wherein R1 is hydrogen, bromine, cyano, formyl, hydroxy, lower alkyl, lower alkenyl, lower alkynyl, lower...
34	5808124	O- or S-substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity Compounds of the formula ##STR1## where the symbols have the meaning described in the application, have retinoid-like or retinoid antagonist-like biological activity.
35	5760048	Alpha-mercaptoacrylic acid derivatives having calpain inhibitory activity The invention covers a novel series of α-mercaptoacrylic acid derivatives that inhibit both calpain I and calpain II with a high affinity and selectivity. The compounds are useful in the treatment ...
36	5741819	Arylsulfonylaminobenzene derivatives and the use thereof as factor Xa inhibitors The present invention is directed to non-peptidic factor Xa inhibitors which are useful for the treatment of arterial and venous thrombotic occlusive disorders, inflammation, cancer, and...
37	5739374	Processes of preparing diphenylheteroalkyl derivatives Diphenylheteroalkyl derivatives of the formula I ##STR1## where A and R1 -R6 have the meanings specified in the description, and the preparation thereof are described.The substances are suitable...
38	5728864	Liquid crystal compound having ferrielectric phase and liquid crystal composition A liquid crystal compound of the formula (1) ##STR1## wherein R is a linear alkyl group having 6 to 12 carbon atoms, both X and Y are hydrogen atoms or one of X and Y is a fluorine atom and the...
39	5723493	Naphthyloxyacetic acid (1) Naphthyloxyaetic acid represented by the compound of the formula (I): ##STR1## and non-toxic salts thereof, (2) process for the preparation of the compounds represented by the compound of the...
40	5705533	10-thio-substituted 1,8-dihydroxy-9 (10H) -anthracenone pharmaceuticals 10-thio-substituted 1,8-dihydroxy-9(10H) anthracenones, therapeutic compositions containing at least one of the 10-thio-substituted 1,8-dihydroxy-9(10H) anthracenones of the invention and methods...
41	5693846	Process for preparation of 4-mercapto-1-naphthol compounds A process for preparation of 4-mercapto-1-naphthol compounds which comprises the steps of: (i) obtaining a 4-heterocyclylthio-1-naphthol compound by reacting a 1-naphthol compound with a...
42	5676923	Substituted DTPA monoamides of the central carboxylic acid group and their metal complexes Diethylenetriaminepentaacetic acid monoamide derivatives, their complexes and complex salts, containing an element of atomic numbers 21-29, 31, 32, 39, 42-44, 49 or 57-83, pharmaceutical agents...
43	5618931	Acetylenes disubstituted with a 5 substituted dihydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity Compounds of the formula ##STR1## wherein the symbols have the meaning described in the specification have retinoid-like biological activity.
44	5574017	Antibacterial agents The present invention provides methods and pharmaceutical preparations for inhibiting the growth of bacterial microorganisms.
45	5536867	Process for the manufacture of dicarboxamides The present invention is directed to a process, and novel intermediates used in the manufacture of, dicarboxamides of the formula I ##STR1## wherein A, G, L, Q, X and Y have the meaning given in...
46	5536874	Process for preparing arylacetic acid and arylpropionic acid derivatives There is provided a process for preparing an arylacetic acid or arylpropionic acid divative from an arylcarbinol which comprises the step of subjecting said arylcarbinol to suitable carbonylation...
47	5536870	Process for preparing olefins A process for preparing olefin compounds of the formula ##STR1## where A is aryl, substituted aryl, heteroaryl, substituted heteroaryl, benzyl, substituted benzyl, vinyl or substituted vinyl and...
48	5530014	Cyclohexadiene derivatives The cyclohexadiene derivatives are prepared by reaction of cyclohexanones with amines and subsequent dehydration. The compounds are suitable as active compounds in medicaments on account of their...
49	5523456	Inhibitors of farnesyl-protein transferase The present invention comprises analogs of the CAAX motif of the protein Ras that is modified by farnesylation in vivo. These CAAX analogs inhibit the farnesylation of Ras. Furthermore, these CAAX...
50	5514683	Bicyclo 2,2,2!octane derivatives The compounds of the formula I ##STR1## and their pharmaceutical acceptable salts, which are defined herein, are ligands for cholecystokinin and/or gastrin receptors.

Matches 1 - 50 out of 363

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