Patents in Class 558/70

Matches 1 - 50 out of 112

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Match	Document	Document Title
1	7595416	Phosphoric acid esters and their use as wetting and dispersing agent The invention relates to a phosphoric acid ester and salts thereof of the general formula (I), wherein A is a monohydroxyl residue derived from C 1 -C 20 -alkyl-(AO)x-OH or Acyl-(AO)x-OH; or C 1 -C...
2	7585997	Compounds and compositions for treating dysproliferative diseases, and methods of use thereof Compounds are disclosed with activity towards killing dysproliferative cells in vitro and treating cancer in vivo. Cancers such as cancer of the colon, pancreas, prostate, lung, breast, urinary...
3	7517868	Phytic citrate compounds and process for preparing the same The present invention provides a chemical compound or a salt thereof having the chemical formula of: wherein said R is H or citrate and wherein at least one R is citrate. The salt of the...
4	7514419	Phosphorus-containing thyromimetics The present invention relates to compounds of phosphonic acid-containing T3 mimetics and monoesters thereof, stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and...
5	7491294	Compositions for reducing paper linting and dusting The present invention relates to a new paper making composition useful for reducing linting and dusting in paper, a method for reducing paper linting and dusting wherein certain phosphate esters...
6	7453006	Inositol derivatives for increasing chloride secretion and inhibiting inflammation Inositol derivatives, compositions comprising inositol derivatives, and methods for using compositions comprising inositol derivatives as agents for activating the secretion of chloride ions and/or...
7	7417035	Phospholipid derivatives of non-steroidal anti-inflammatory drugs Disclosed are compounds having non-steroidal anti-inflammatory drugs (NSAIDS) covalently linked to a phospholipid moiety via a bridging group. Also disclosed are a process for the synthesis of the...
8	7410956	Caspase inhibitor prodrugs The present invention relates to compounds of formula I which are prodrugs of caspase inhibitors and pharmaceutically acceptable salts thereof. This invention further relates to the release of...
9	7408075	Synthesis of phosphocholine ester derivatives and conjugates thereof Aspects of the present invention include methods of synthesizing phosphocholine analogues and the phosphocholine conjugates formed therefrom and their use in preventing infections caused by...
10	7384978	Compounds and methods for delivery of prostacyclin analogs This invention pertains generally to prostacyclin analogs and methods for their use in promoting vasodilation, inhibiting platelet aggregation and thrombus formation, stimulating thrombolysis,...
11	7384925	Functionalized stilbene derivatives as improved vascular targeting agents Novel stilbenoid compounds and their prodrug forms are disclosed, which serve as potent vascular targeting agents useful for the treatment of solid tumor cancers and other diseases associated with...
12	7304093	Ketone compounds and compositions for cholesterol management and related uses The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias,...
13	7304046	Phosphoramide compounds The invention provides a compound of formula I: wherein R 1 , R a , R b , R c , and R d have any of the values defined in the specification, as well as pharmaceutical compositions comprising...
14	7217831	Insecticide and method of controlling insects An insecticide of formula 1 and the agriculturally acceptable salts thereof, wherein: R 1 is selected from the group consisting of: the group OR 5 wherein R 5 is selected from the group...
15	7214811	Derivative of phosphoric acid ester salt or phosphoric acid ester adduct or mixtures thereof, method for the production thereof and their use A derivative of phosphoric acid ester salt or adduct or a mixture thereof is obtained from a reaction product, polycondensed with at least one aldehyde, of at least one polyol phosphoric acid ester...
16	7166736	Neopentylglycol bis(diaryl phosphate) esters Neopentyl glycol bis(diphenyl phosphate) liquid compositions are described that comprise from about 75% to about 90%, by weight, of neopentyl glycol bis(diphenyl phosphate), less than about 5% by...
17	7138356	Alkoxylated phosphite ester and process therefor A composition and a process for producing the composition are disclosed. The composition comprises an alkoxylated phosphite ester which has the formula of (HO[{CH(R)} m O] n ) 3 P in which each R...
18	7129229	Hydrazide building blocks and hydrazide modified biomolecules This invention relates to attachment chemistries for binding macromolecules to a substrate surface or to other conjugation targets. More particularly, this invention relates to attachment...
19	7122699	Process for preparing organic boronic acid derivatives using diboronic acid The invention relates to a process for the preparation of organic boronic acid derivatives involving the reaction of an organic compound with diboronic acid in the presence of a Group 8-11 metal...
20	7102024	Functional biopolymer modification reagents and uses thereof Hydrazino, oxyamino and carbonyl-based reagents and methods for incorporation into oligonucleotides during their solid phase synthesis are provided. Modified oligonucleotides are provided that...
21	7094557	2-Methyl-3-butenyl-1-pyrophosphoric acid salt and agent for treating lymphocytes A pharmaceutically acceptable salt of 2-methyl-3-butenyl-l-pyrophosphoric acid; an agent for treating lymphocytes which comprises at least one of 2-methyl-3-butenyl-l-pyrophosphoric acid, a...
22	7057061	Chiral monophosphorus compounds The present invention relates to catalysts comprising chiral monophosphorus compounds and their use, the chiral monophosphorus compounds themselves and also their precursors.
23	7009067	Hexa-citrated phytate and process of preparation thereof The present invention relates to a new chemical compound known as hexa-citrated phytate and a method of production thereof. The new chemical compound has six citrate molecules attached at the...
24	6914148	Guanidinium functionalized intermediates The present invention provides oligomers which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the nucleoside moieties of the oligomer is modified to...
25	6909010	Facile synthesis of symmetric esters of alkylenebisphosphonic acids A facile synthesis of symmetric esters of C 1 -C 10 alkylenebisphopsphonic acids is disclosed in which a C 1 -C 10 alkylenebis(phosphonic dichloride) is reacted with an alcohol in the presence of...
26	6794528	Phosphorus compound The phosphorus-containing compound of the present invention is represented by the following formula (I), (II) or (III): wherein Z 1 , Z 2 and Z 3 each represents a cycloalkane, a cycloalkene,...
27	6759461	Phenolic phosphite antioxidants and polymer compositions containing said antioxidant A novel antioxidant has the advantages of both the hindered phenols and the phosphite antioxidant is prepared from phosphorus trichloride and 2,5-di-tert-butylhydroquinone, such as...
28	6743921	Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds The present invention provides a process for the preparation of a nonracemic diastereomer of 1-(4-benzoxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1 -propanol by hydrogenation of a...
29	6703518	Fluoride-releasing compositions Chelating monomers and fluoride-releasing compositions are disclosed that may be incorporated into dental composite restorative materials or other dental materials, to produce materials with high...
30	6677471	Intermediates for the synthesis of oligonucleotide analogues Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. Also provided are synthetic...
31	6626988	Phosphate-stabilized polyurethane materials, cross-linked by condensation, method for their production and use thereof The invention relates to polyurethane materials, cross-linked by silane polycondensation, containing alkoxylsilane functional polyurethanes, alkaline fillers, phosphorous compounds aminosilanes,...
32	6613926	Perchloramido phosphonyl reagents and analogs thereof Novel compounds are provided in the form of nucleoside pyrophosphate and triphosphate analogs. In these analogs, the pyrophosphate or triphosphate group is replaced with a moiety that is...
33	6610837	Phosphate and thiophosphate protecting groups Novel P(III) bisamidite reagents as phosphorus protecting groups, nucleoside phosphoramidite intermediates, and synthetic processes for making the same are disclosed. Furthermore, oligomeric...
34	6593376	Amphiphilic compounds with at least two hydrophilic and at least two hydrophobic groups on a di-,oligo- or polyene base A process for preparing amphiphilic compounds having at least two hydrophilic and at least two hydrophobic groups by reacting an olefinic substrate having at least two double bonds with an organic...
35	6576782	Halogenation of protected phenols in meta position The invention concerns a halogenation in position meta of a phenol fuction. Said halogenation comprises a step which consists in halogenating an aromatic derivative of a medium or advantageously...
36	6534050	2-methyl-3-butenyl-1-pyrophosphoric acid salts and agents for treating lymphocytes A pharmaceutically acceptable salt of 2-methyl-3-butenyl-1-pyrophosphoric acid; an agent for treating lymphocytes which comprises at least one of 2-methyl-3-butenyl-1-pyrophosphoric acid, a...
37	6531590	Processes for the synthesis of oligonucleotide compounds Methods for the preparation of oligonucleotides having bioreversible phosphate blocking groups are disclosed. The oligonucleotides are prepared utilizing amidite type chemistry wherein the...
38	6531591	Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized...
39	6521775	Process for the synthesis of oligomeric compounds Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. Also provided are synthetic...
40	6465687	Thyroid receptor ligands and method Novel thyroid receptor ligands are provided which have the general formula (I) where R 1 is alkyl of 1 to 4 carbons or cycloalkyl of 3 to 7 carbons; R 2 and R 3 are the same or different and...
41	6440952	Phosphono-carboxylate compounds for treating amyloidosis Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of...
42	6437165	Phosphate derivatives as immunoregulatory agents Immunoregulatory compounds are disclosed of the formula: as well as the pharmaceutically acceptable salts and hydrates thereof, are disclosed. The compounds are useful for treating immune...
43	6437164	Process for the preparation of phosphonite compounds Biphenyl and phosphorus trichloride are reacted in the presence of aluminum chloride, a hydrogen chloride gas generated is removed, a pyridine is added, excess phosphorus trichloride is removed, a...
44	6307098	Water soluble phosphines This invention relates to water soluble phosphines of the following structural formula and method of preparing these phosphines: ##STR1## Wherein A is a moiety which is stable to the reaction...
45	RE37355	6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds, methods of preparing them and the use of these compounds in drugs are described.
46	6251833	2-arylcyclopentan-1,3-diones The present invention relates to novel 2-aryl-3-hydroxy-Δ 2 -cyclopentene-1-one derivatives of the formula (I) ##STR1## in which A, B, D 1 , D 2 , G, W, X, Y and Z are each as defined in the...
47	6194598	Aminooxy-modified oligonucleotide synthetic intermediates Nucleotide compositions containing aminooxy moieties are provided. In accordance with preferred embodiments, oligonucleotides and oligonucleotide analogs are provided which are specifically...
48	6191171	Para-aminomethylaryl carboxamide derivatives para-Aminomethylaryl carboxamides of Formula I are antagonists of VLA-4 and/or α 4 β 7 , and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated...
49	6172209	Aminooxy-modified oligonucleotides and methods for making same Oligonucleotides and other macromolecules are provided which have increased nuclease resistance, substituent groups (such as 2'-aminooxy groups) for increasing binding affinity to complementary...
50	6160152	Process for the synthesis of oligomeric compounds Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, and phosphorodithioate covalent linkages. Also provided are synthetic...

Matches 1 - 50 out of 112

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