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7632960 |
Process for the preparation of nitric esters of monohydric alcohols
The present invention relates to a process for the preparation of nitric esters of monohydric alcohols wherein a monohydric alcohol or a mixture of monohydric alcohols is converted with nitric acid...
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7335789 |
Process for the mononitration of alkanediols
A process for the preparation of compounds of formula (I):
HO-A-ONO 2 (I)
...
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7238829 |
Process for the preparation of naproxene nitroxyalkylesters
A process for obtaining nitroxyalklesters of the 2(S)(6-methoxy-2-naphthyl)-propanoic acid having an enantiomeric excess higher than or equal to 95%, preferably higher than or equal to 98%,...
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7186753 |
Pharmaceutical compounds
Compounds or their salts of general formula (I): A—B—N(O) s wherein: s is an integer equal to 1 or 2; A=R—T 1 —, wherein R is the drug radical and T 1 =(CO) t or (X) t′ , wherein X=O,...
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7160920 |
Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders
Disclosed are (i) compounds of a steroid, a β-agonist, an anticholinergic, a mast cell stabilizer and a phosphodiesterase (PDE) inhibitor directly or indirectly linked to a NO or NO 2 group or a...
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6677374 |
Nitrate esters and methods of making same
Compounds and methods for mitigating neurodegeneration, effecting neuroprotection and/or effecting cognition enhancement in a subject are described. Neurological or cognitive conditions are treated...
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6548693 |
Nitriloxy derivatives of (R) and (S)-carnitine
Carnitine derivatives of formula (I) are described in racemic and/or optically active form, as well as the process for their preparation and their use as pharmaceutical anti-angina active...
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6325876 |
Energetic plasticizers containing 3,3-bis(difluoroamino)-1,5-dinitratopentane and method of preparation
A compound has the structure of 3,3-bis(difluoroamino)-1,5-dinitratopentane and is useful in energetic materials.
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6211233 |
Prostaglandin pharmaceutical compositions
Compounds of the general formula A--X 1 --NO 2 , or their pharmaceutical compositions, wherein A contains a prostaglandin residue, X 1 is a bivalent connecting bridge.
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6180664 |
Pentaerythritol derivatives, their production and use and intermediates for their synthesis
The invention describes novel compounds derived from pentaerythritol of general formula I, XIV, XVI, XIX and XXII, the substituents being as defined in the description, which can be used as...
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6072071 |
Process for the production of dinitrate esters
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5861426 |
Nitro compounds of the formula A-X.sub.i -NO.sub.2 and their compositions having anti-inflammatory, analgesic and anti-thrombotic activities
New compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic activities, of the general formula: A--X 1 --NO 2 or their salts, wherein: A is R(COX u ) t , wherein...
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5705527 |
Amino acid derivatives
An amino acid compound of the formula: R 1 NH--CH(R 2 )--COHN--A--ONO 2 , wherein R 1 represents a hydrogen atom, a C 1 -C 7 alkanoyl group, a C 1 -C 6 alkoxycarbonyl group, a C 6 -C 10 ...
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5700947 |
Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation
This invention is directed to nitric esters of derivatives of propionic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid, 5-benzoyl-1,2-dihydro-3H-pyrrolo...
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5661129 |
Organic nitrates containing a disulfide group as cardiovascular agents
The invention relates to novel nitrates containing a disulphide group, and to processes for their preparation. The compounds can be used for the therapy of disorders of the cardiovascular system.
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5597847 |
Nitric esters of derivatives of the 2-(2,6-di-halo-phenylamino) phenylacetic acid and process for their preparation
Object of this invention are nitric esters of derivatives of the 2-(2,6-di-halophenylamino)phenylacetic acid, having the following general formula: ##STR1## wherein: A and B are selected from among...
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5454842 |
Cetane improver compositions comprising nitrated fatty acid derivatives
The present invention is directed to materials which improve the cetane number of diesel fusel when added in an amount in the range of 0.01 to 2 wt % to such fuel. The materials are the nitration...
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5428061 |
Organic nitrates and method for their preparation
New organic nitrate compounds, formed by condensing a nitrato alkanoic acid with a sulfur-containing amino acid or peptide, which prevent nitrate tolerance or overcome existing tolerance and which...
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5313000 |
Polymerization of cyclic ethers
This invention relates to the production of hydroxy-terminated polymers in the 2,000-20,000 MW range suitable for use as prepolymers in curing reactions with isocyanates to produce elastomers. The...
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5284872 |
Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof
New organic nitrate compounds, formed by condensing a nitrato alkanoic acid with a sulfur-containing amino acid or peptide followed by the reaction of the resulting product with an amino acid,...
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5264596 |
Isotactic poly(glycidyl nitrate) and synthesis thereof
Isotactic poly(glycidyl nitrate) useful in solid propellants is produced by polymerizing chiral (R) glycidyl nitrate or its enantiomer, (S) glycidyl nitrate. Chiral (R) glycidyl nitrate or its...
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5099042 |
Synthesis of tetrafunctional polyethers and compositions formed therefrom
Polymers are produced from 4 and 5 member cyclic ethers, which polymers have hydroxyl functionalities of 4. The cyclic ethers are polymerized with an acid catalyst and a tetraol initiator having...
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5089652 |
Nitrate ester preparation
The process of the present invention provides a method of obtaining a high yield of water or acid soluble nitrate esters without the use of organic solvents in the nitration reaction or the...
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5037849 |
Pharmaceutical compositions containing nitroxyalkylamines, novel nitroxyalkylamines and processes for the preparation thereof
The present invention provides pharmaceutical compositions effective against angina-like heart and circulatory diseases containing at least one nitroxyalkylamine derivative of the general formula:...
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4985584 |
Process for the production of high energy materials
A process for the production of a high energy nitrate ester involves reacting, in an inert organic solvent, a heterocyclic compound, selected from oxiranes, oxetanes, N-substituted aziridines and...
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4863949 |
Aminopropanol derivatives, processes for the preparation thereof, the use thereof and pharmaceutical compositions containing them
The present invention provides compounds of the general formula: ##STR1## wherein Ar is a substituted or unsubstituted aromatic or heteroaromatic radical, A is a straight-chained or branched...
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4853157 |
Process for the manufacture of nitric acid esters
A process for the preparation of nitric acid esters of organic hydroxy compounds by reacting an organic hydroxy compound with nitric acid in the presence of both sulphuric acid and in a solvent,...
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H000644 |
Method for preparing 2,2,2-trinitroethyl 2-nitroxyethyl ether
A process for preparing 2,2,2-trinitroethyl 2-nitroxyethyl ether by the fowing reaction sequence: ##STR1## 2,2,2-Trinitroethyl 2-nitroxyethyl ether is useful as an energetic plasticizer in...
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4820859 |
Process for the production of high energy material
A process for the production of a high energy material involves reacting, in an inert organic solvent, a heterocyclic compound selected from oxirane, aziridine, oxetane or azetidine with a nitrogen...
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4780560 |
Nitrate derivatives and vasodilators containing the same
Novel nitrate derivatives are disclosed. As examples of said nitrate derivative are described N-(β-hydroxyethyl)-5-(3,4,5-trimethoxyphenyl)2,4-pentadieno
ic acid amide nitrate,...
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4745208 |
2,2,2-trinitroethyl 2-nitroxyethyl ether and a method of preparation
2,2,2-trinitroethyl 2-nitroxyethyl ether (TNEN), C(NO 2 ) 3 CH 2 CH 2 CH 2 ONO 2 , which is prepared by the following reaction sequence: C(NO 2 ) 3 - K + +ClCH 2 OCH 2 CH 2 BR➝C(NO 2 )...
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4571436 |
Process for producing optically active cyclopentenolones
Optically active cyclopentenolones, which are useful as an intermediate of pyrethroid insecticides, are produced from racemic cyclopentenolones according to the following procedures; (1) asymmetric...
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4552703 |
Production of optically active cyclopentenolones
Optically active cyclopentenolones, useful as an intermediate to be directed to pyrethroid insecticide, are produced starting from the optically active cyclopentenolones with the opposite...
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4522756 |
Alkyl, azido, nitro ethers and method of preparation
A family of compounds using as energetic plasticizers having the general structural formula R--N(NO 2 )--CH 2 CH 2 CH 2 (OCH 2 CH 2 ) 2 X wherein R is an alkyl group having from 1 to 10 carbon...
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4479905 |
Nitration process
A mixture of aliphatic primary monohydric alcohol and alkoxyalkanol is continuously nitrated by reaction with a nitric-sulfuric acid mixture at -10° to 15° C. to yield an organic nitrate mixture...
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4417903 |
Diesel fuel composition
The cetane number of diesel fuel is increased by the addition of an aliphatic hydrocarbyl nitro nitrate additive such as 2-methyl-2-nitro-1-propanol nitrate (ester).
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4352699 |
Co-nitrating trimetholethane and diethylene glycol
It has been discovered that when co-nitrating a mixture of trimethylolethane and diethylene glycol, a storage stable spent acid can be obtained if during the co-nitration an excess of from about 60...
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4251455 |
Continuous closed loop nitration of polyhydric alcohols
A process for the continuous manufacture of a nitric acid ester of a polyhydric alcohol by reacting the polyhydric alcohol with nitrating acid, comprising circulating a stream of waste nitrating...
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4118414 |
Difluoramino compounds and perfluoroguanidine-pentaerythrityl nitrates
Tris(difluoramino)methoxypentaerythrityl nitrates and perfluoroguanidine adducts of pentaerythrityl nitrates, useful as propellant ingredients, are disclosed.
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3950385 |
Preparation of nitronitrates
A method for preparing vicinal nitronitrates by simultaneously contacting an alkene with oxygen and dinitrogen tetroxide in the presence of concentrated sulfuric acid. The nitronitrates so formed...
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3914254 |
Basic esters of polyhydro-2-phenanthrylidene-acetic acids
Alkyl polyhydro-2-phenanthrylideneacetates are prepared by interacting the corresponding 2-oxopolyhydrophenanthrenes with a tri-lower-alkyl α-phosphono-lower-alkanoate. Said alkyl...
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3706808 |
PRODUCTION OF NITROALKANES
A process for the production of a nitroalkane or dinitroalkane by reacting an olefin or diolefin with nitric acid in the presence of a lower aliphatic monocarboxylic acid anhydride, thereby...
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3428667 |
N,N-DINITRAMINES OF CERTAIN ORGANIC COMPOUNDS AND PROCESS
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3426013 |
DIFLUORAMINATED DIALDEHYDE CELLULOSE AND NITRIC ACID ESTERS THEREOF
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3420869 |
UNSATURATED NITRATED ESTERS
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3378576 |
Nitrate esters of tetrahydroxy-3, 6-dinitrocyclohexane
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3366665 |
Nitrate esters of difluoroamino alkyl ethers
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3347903 |
Difluoroamino alkyl nitrate preparation
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3346619 |
Process for preparing an nf2-containing nitrate
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3344167 |
Difluoraminoalkyl nitrates
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