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8026245 |
HIV replication inhibiting purine derivatives
The present invention relates to the use of a compound of formula (I) for the manufacture of a medicament for the prevention or the treatment of HIV infection wherein the compound of formula (I) is...
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7498126 |
Photoacid generators, chemically amplified resist compositions, and patterning process
A photoacid generator has formula (1). A chemically amplified resist composition comprising the photoacid generator has advantages including a high resolution, focus latitude, long-term PED...
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7390899 |
Process for the synthesis of high purity 3,5-diamino-6-(2,3-dichlorophenyl) (1,2,4-triazine)
The present invention relates to a new process for the synthesis of high purity 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine of formula (I) using 2,3-dichlorobenzoyl cyanide and an...
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7317066 |
Liquid crystal polymers
Liquid crystal polyester derived from phenylene-naphthalene monomers and one or more comonomers display an improved balance of properties, including low melt viscosity, fast cycle time in molding,...
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7034045 |
Monofluoroalkyl derivatives
The present invention provides certain monofluoroalkyl derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions,...
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7026094 |
Substituted oxime derivatives and the use thereof as latent acids
New oxime sulfonate compounds of the formula (I) and (II), wherein R1 is C1-C12alkyl, C1C4haloalkyl, hydrogon, OR9, NR10R11, SR12 or is phenyl which is unsubstituted or substituted by OH,...
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6900353 |
Cyclopentyl sulfonamide derivatives
The present invention provides compounds of formula (I): useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as...
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6699904 |
PPAR agonists
PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and...
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RE37087 |
Insecticidal triffluormethyl alkane derivatives
There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1##in which R1, R2, R3, R4 and A have the meanings given in the description, processes for their preparation...
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6165237 |
Fuel and lubricant additives
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6020515 |
Process for the preparation of malononitrile
A novel process for the preparation of malononitrile which involves subjecting a (2-cyano-N-alkoxy)acetimidoyl halide to a high-temperature treatment.
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6004724 |
Oxime sulfonates and the use thereof as latent sulfonic acids
New oximsulfonate compounds of the formulae I or II, ##STR1## wherein m is 0 or 1; x is 1 or 2; R1 is, for example phenyl, which is unsubstituted or substituted or R1 is a heteroaryl radical that...
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5968978 |
Biphenylsulfonylcyanamides, process for their preparation, and their use as medicament
Compounds of the formula I ##STR1## in which the symbols have the meanings indicated in the claims, have outstanding antiarrhythmic properties. They exhibit a cardioprotective component. They can...
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5932766 |
Process for the preparation of substituted keto-enamines
The present invention discloses a process for the preparation of a compound having formula 4: ##STR1## The process comprises the step of reacting an enolate having the formula: ##STR2## with a...
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5859279 |
Compound and process
A process for the preparation of a compound of formula (VI), optionally in enantiomerically-enriched form (R or S), comprises chemoselective reduction of a novel compound of formula (V), wherein...
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5846999 |
Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones
The compounds of the formula: ##STR1## wherein R1 is straight chain alkyl, branched chain alkyl, cycloalkyl, hydroxyalkyl, fluoroalkyl or polyfluoroalkyl; R2 and R3 are, independently, hydrogen or...
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5834618 |
Process for the preparation of 3-amino-2-hydroxy-4-phenylbutyronitrile derivatives
3-Amino-2-hydroxy-4-phenylbutyronitrile derivatives represented by the formula (3) may be prepared by reacting an aminoaldehyde derivative represented by the formula (1) with a cyanohydrin...
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5763639 |
Process for producing quarternary glycine nitriles
A process for preparing quaternized glycine nitriles of formula I ##STR1## comprising reaction of the corresponding precursor amine, aldehyde, hydrocyanic acid or alkali metal cyanide, and...
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5703266 |
3-substituted para-aminophenols
The invention concerns the use of a 3-substituted para-aminophenol as an oxidation dye precursor for dyeing keratinous fibres, in particular human hair. The 3-substituted para-aminophenol has...
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5631405 |
Method of forming amino acid-derived diaminopropanols useful as chemical intermediates for protease-inhibitors
The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs,...
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5629442 |
Process for producing α-hydroxyiminophenylacetonitriles
A process is disclosed to produce an α-hydroxyiminophenylacetonitrile of the general formula [II]: ##STR1## wherein R1, R2, R3 and Z are each as defined in the specification, characterized in that ...
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5618966 |
Method forming protease inhibitor synthetic intermediates
The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs,...
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5571942 |
Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes
The present invention provides novel ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes which exhibit binding activity at the serotonin 1A receptor.
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5543573 |
Hydrazinecarboxyamide derivatives, a process for production thereof and uses thereof
The present invention relates to a hydrazinecarboxamide derivative of the general formula (I) shown below: ##STR1## wherein the substituents are as defined in the specification, which has a wide...
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5530014 |
Cyclohexadiene derivatives
The cyclohexadiene derivatives are prepared by reaction of cyclohexanones with amines and subsequent dehydration. The compounds are suitable as active compounds in medicaments on account of their...
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5498745 |
Substituted di-t-butylphenols
Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an...
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5492641 |
β-aminonitriles and N-alkyl-1,3-propylenediamines and their use as fuel additives and lubricant additives
β-Aminonitriles of the following formula I ##STR1## where R1 is an aliphatic hydrocarbon radical having alkyl side groups and a number average molecular weight of from 250 to 5,000 and R2, R3 and ...
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5476960 |
αaminonitriles derived from reaction of carbonyl compounds and fatty aklyl alkylene diamines
An α-aminonitrile compound derived from the reaction, in the presence of a cyanide source of (1) a bisulfite adduct of a carbonyl compound selected from the group consisting of an aldehyde and a ...
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5475138 |
Method preparing amino acid-derived diaminopropanols
The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs,...
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5457131 |
Cyclopentane(ene) heptanoic or cyclopentane(ene) heptenoic acid, 2-hydrocarbyl sulfonamidomethyl and derivatives thereof as therapeutic agents
The present invention relates to cyclopentane heptanoic or cyclopentane heptenoic acid, 2-hydrocarbyl sulfonamidomethyl, and derivatives thereof, useful as therapeutic agents. In particular, the...
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5451607 |
Hydrazone derivatives, process for producing same, insecticides and/or acaricides containing same as active ingredient and intermediate compounds thereof
There are disclosed hydrazone derivatives of the general formula [I]: ##STR1## wherein R1 is halogen, etc.; R2 is hydrogen or C1 -C6 alkyl, etc.; R3 is hydrogen or C1 -C6 alkyl, etc.; R4 is...
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5416111 |
Cyano-containing n-phenyl-amino-terminated non-peptidyl α-succinamidoacyl aminodiols as anti-hypertensive agents
Non-peptidyl compounds characterized generally as α-succinamidoacyl aminodiols containing a cyano group and having an N-phenyl-amino-type group at the N-terminus are useful as renin inhibitors for ...
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5391808 |
Substituted 1,4-diamino-2-butene stabilizers
N,N,N',N'-Tetrasubstituted 1,4-diamino-2-butenes where the substituents are alkyl, cycloalkyl, aralkyl, aryl or mixtures thereof provide effective antioxidant protection to lubricants and/or...
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5380755 |
Alkyl and alkylbenzyl ethers of substituted hydroquinones
The present invention provides alkyl and alkylbenzyl ethers of substituted hydroquinones and pharmaceutical compositions containing them. The present invention further provides methods of using...
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5374762 |
α-aminomononitriles containing fatty alkyl C12 to C22 group
α-aminonitrile compounds derived from a fatty alkyl alkylene diamine containing two reactible amino functionalities are disclosed which are of the formula ##STR1## where R is C12 -C22 fatty alkyl, ...
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5374763 |
α-aminodinitriles containing fatty alkyl C12 to C22 group
α-aminonitrile compounds derived from a fatty alkyl alkylene diamine containing two reactible amino functionalities are disclosed which are of the formula ##STR1## where R is C12 -C22 fatty alkyl, ...
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5334745 |
Preparation of 3-aminopropionitriles
3-Aminopropionitriles of the general formula I ##STR1## where R1,R2,R3,R4 and R5 independently of one another are each hydrogen, C1 -C20 -alkyl, C1 -C8 -aminoalkyl, C1 -C8 -cyanoalkyl, C3 -C20...
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5332825 |
Single vessel synthesis of aminoacetonitriles
This invention relates to two processes for preparing aminoacetonitriles in one vessel under anhydrous conditions. Process I involves the steps of: (A) reacting trimethylsilyl cyanide and an...
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5332826 |
Process for preparing aminoacetonitriles in one vessel
This invention relates to a process for preparing aminoacetonitriles in one vessel. The process involves the steps of: (A) reacting an alkali metal cyanide with an aldehyde in water to form a...
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5319126 |
α-aminonitriles derived from fatty alkyl alkylene diamines
α-aminonitrile compounds derived from a fatty alkyl alkylene diamine containing two reactible amino functionalities are disclosed.
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5290806 |
4-(4-tert-butylphenyl) cyclohexylamines, and fungicides containing same
4-4(tert-butylphenyl)-cyclohexylamines and quaternary ammonium salts thereof of the formulae ##STR1## where R1 is hydrogen, alkyl or alkenyl, R2 is alkyl, haloalkyl, hydroxyalkyl, cycloalkyl,...
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5247119 |
Phenylacetonitrilehydroxyalkylaminoalkyl-ortho-substituted aryl compounds as immunosuppressives
A class of substituted phenylacetonitrilehydroxyalkylaminoalkyl-ortho-substituted aryl compounds having immunosuppressive properties is described. Compounds of this class would be useful in...
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5223536 |
1,4-diaryl-1-cyclopropyl-4-substituted butanes as insecticides and acaricides
The 1,4-diaryl-1-cyclopropyl-4-substituted butane pesticides of the following formula are effective as insecticides and acaricides: ##STR1## in which X and Y are independently hydrogen, halogen,...
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5196147 |
Organic nonlinear optical substance
An organic nonlinear optical substance having the formula (I): ##STR1## wherein R1 represents --H or --CH3 ; n is 0, 1, or 2; A represents Z1 --Ar, ##STR2## wherein Ar represents a 6-14 membered...
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5196562 |
Substituted 1,3,5-triazinetriones, for use against parasitic protozoa
Protecting against parasitic protozoa with substituted 1,3,5-triazinetriones of the formula ##STR1## in which R1 represents aromatic or heteroaromatic radicals, each of which is optionally...
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5180744 |
Aralkyl-N-terminal amino hydroxy
Non-peptidyl compounds characterized generally as aralkyl-N-terminal amino hydroxy β-amino acid derivatives are useful as renin inhibitors for treatment of hypertension. Compounds of particular ...
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5169973 |
Synthesis of alpha-aminonitriles
Alpha-aminonitriles can be synthesized by the reaction, at ambient temperature without use of catalyst, of essentially stoichiometric amounts of amine, aldehyde (either monoaldehyde or dialdehyde)...
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5169865 |
Method and composition for calcium binding, translocation and mediating
A method, and mediating agents are provided for mediating the physiological effects of hormones, neurotransmitters, calcium-channel antagonists, chemotactic peptides or chemotactic proteins. The...
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5167696 |
Herbicidal aryloxy- and arylamino-indanes
A compound of formula (I): ##STR1## in which Ar is an optionally substituted aryl or heterocyclic ring system; W is O or NR1 where R1 is hydrogen or lower alkyl; A is CH or >CH2 and G is ...
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5147892 |
Benzyl ketones and fungicides containing them
Benzyl ketones of the formula ##STR1## where X is CH or N, Y is O or NR4, R1, R2 are H or alkyl, R3 is halogen, cyano, nitro, alkyl, cycloalkyl, alkoxy, haloalkyl, arylalkyl, arylalkoxy, aryloxy or...
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