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7855228 Antibiotics targeting MreB  
The identification of MreB as essential for bacterial chromosome segregation provides a new target for antibiotic action. The MreB function is useful in the development of screening assays for new...
6124351 Amino acid derivatives having a nitric oxide synthase inhibiting action  
Compounds represented by the general formula (I): ##STR1## (where R1 denotes a hydrogen atom, a straight-chained or branched alkoxycarbonyl group having 1-6 carbon atoms in which the alkyl portion...
5414028 Carbohydrate substituted dibenzo[d,f][1,3,2]dioxaphosphepin stabilizers  
Carbohydrate substituted dibenzo[d,f][1,3,2]dioxaphosphepin compounds of formula I ##STR1## where A is a carbohydrate residue are effective stabilizers for polymers processed at elevated...
5256694 Diarylacetylenes, their preparation and their use  
Novel diarylacetylenes of the formula I ##STR1## where A, R1, R2, R3, R4, R5 and R6 have the meanings stated in the description, are useful for the treatment of disorders.
5254335 Hair conditioning compounds containing reactive nonionic surfactants and isothiuronium compounds and method of use  
Novel isothiuronium surfactant salts are useful as hair conditioning agents. Aqueous composition containing such salts, and method of using the salts are disclosed.
5114975 Anilinophenyl carbodiimides compositions containing them, and the use thereof in pest control  
The invention relates to novel substituted aryloxyphenylthioureas, aryloxyphenylisothioureas and aryloxyphenylcarobodiimides of formula I ##STR1## wherein R1 is C1 -C12 alkyl, unsubstituted or...
5091415 Thioformamidines, their preparation and use as medicaments  
Formamidine compounds of general formula I ##STR1## in which: R1 represents H or C1-4 alkyl, R2 represents benzoyl, benzyl, or alpha-hydroxybenzyl, the aromatic ring being optionally substituted by...
5026730 Anilinophenylthioureas, compositions containing them, and the use thereof in pest control  
The invention relates to novel substituted anilinophenylthioureas, anilinophenylisothioureas and anilinophenylcarbodiimides of formula I ##STR1## wherein R1 is C1 -C12 alkyl, unsubstituted or...
4965389 Phenoxyphenylthioureas phenoxyphenylisothioureas and phenoxyphenylcarbodiimides and use thereof for controlling pests  
The invention relates to novel phenoxyphenylthioureas, phenoxyphenylisothioureas and phenoxyphenylcarbodiimides of formula I ##STR1## wherein R1 is C3 -C7 cycloalkyl or C5 -C6 cycloalkenyl, R2 is...
4954627 Process for desulfurization of isothioureas and isothioamides  
The present invention is directed to a process for desulfurizing a compound selected from isothioureas and isothioamides comprising heating the compound to be desulfurized in the presence of a...
4897424 Aryloxyphenylthioureas, aryloxyphenylisothioureas and aryloxyphenylcarbodiimides and pesticidal compositions containing them  
Novel substituted aryloxyphenyl-thioureas, -isothioureas and -carbodiimides of formula I ##STR1## in which R1 represents C1 -C12 alkyl, C1 -C12 alkyl mono- or poly-substituted by halogen and/or by...
4748186 S-trifluorobutenyl derivatives and pesticidal uses thereof  
S-trifluorobutenyl thiocarbonic acid esters of the formula ##STR1## and salts thereof, wherein X is R1 N or S and Y is RS or R3 R2 N; wherein R is a metal or a radical selected from alkyl,...
4727142 Process for the preparation of imidates  
The invention relates to a process for the preparation of compounds of the formula I and salts or acid addition compounds thereof ##STR1## in which R denotes hydrogen, (halogenated) alkyl with the...
4710578 Isothiuronium salts  
According to the present invention there are provided isothiuronium salts of the general Formula I ##STR1## wherein R1 is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, aralkyl or aryl,...
4692467 N'-cyano-n-tetrahydrownaphthyl-s-methyisothiourea as a growth promoting agent  
This invention relates to novel cyanoguanidine compounds and the intermediate N'-cyano-N-(1,2,3,4-tetrahydro-1-naphthyl)-S-methylisothiour ea. These novel compounds are useful as animal growth...
4689348 Cyanoguanidines useful as animal growth promoting agents  
This invention relates to novel cyanoguanidine compounds and the intermediate N'-cyano-N-(1,2,3,4-tetrahydro-1-naphthyl)-S-methylisothiour ea. These novel compounds are useful as animal growth...
4649138 Pharmaceutical compositions  
S-(Aminoalkyl)isothioureas which have immunosuppressant activity. Two specific compounds are 2-(3-dimethylaminopropylthio)-2-imidazoline and N,N'-dimethyl-S-(3-dimethylaminopropyl)isothiourea.
4647665 Preparation of sulphonyliso(thio)ureas and sulphonylisoureas  
A process for the preparation of a sulphonyliso(thio)urea of the formula ##STR1## in which R1 represents an optionally substituted radical from the group consisting of alkyl, aralkyl, aryl and...
4619944 Antihypertensive compounds  
Provided are antihypertensive compounds of the formula ##STR1## wherein R1, R2, R3, R4, R5, and R6 are hydrogen, alkyl, alkenyl, alkynyl, phenyl-alkyl, or cycloalkyl, and may be the same or...
4514418 2,2-Dihalogeno-3,3-dimethylcyclopropane derivative fungicides  
A 2,2-dihalogeno-3,3-dimethylcyclopropylmethyl derivative of the formula ##STR1## in which X and Y each independently is halogen, R is a hydrogen atom or a methyl group, Z is a cyano group, a...
RE31588 Imidazolylmethylthioethyl alkynyl guanidines  
Compounds of the formula ##STR1## wherein R1 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive, and nontoxic pharmaceutically acceptable acid addition...
4421550 Herbicidal triazole ureas  
Triazole ureas demonstrate utility as agricultural chemicals and in particular as herbicides.
4419297 Preparation of nitriles from formamides  
Aliphatic, araliphatic or aromatic nitriles of the formula R--CN are obtained by reacting N-substituted formamides of the formula R--NHCHO with at least the stoichiometric quantity of an acylating...
4414221 Pesticidal 1,2,4-triazole compounds  
The compounds of the formula: ##STR1## wherein R1 represents phenyl substituted in at least the 2-position by fluorine, chlorine, bromine or iodine, R2 represents a group R3, --OR3, --SR3 or --NR3...
4328248 Isothiourea derivatives having pesticidal activity  
Compounds of the formulae I and II ##STR1## wherein R1, R2 and R3 independently of one another are each hydrogen, C1 -C4 -alkyl, methoxy, halogen, trifluoromethyl or nitro, R4 is hydrogen or...
4328247 Phenoxyphenylisothioureas, production thereof and use thereof in pest control, and phenoxyphenylthioureas as intermediates for the production of the phenoxyphenylisothioureas and use thereof in pest control  
The invention relates to N-phenoxyphenylisothioureas of the formula ##STR1## wherein each R1, R2 and R3 is hydrogen, halogen, C1 -C4 alkyl, C1 -C4 alkoxy, trifluoromethyl or nitro, each of R4 and...
4310539 Biocidal isothiourea compounds  
Novel biocidal S-aminoalkyl isothiourea compounds have the general structural formula ##STR1## wherein X is halogen; R is a straight or branched chain alkyl radical containing 5 to 20 carbon atoms;...
RE30457 Pharmacologically active compounds  
The compounds are substituted S-(aminoalkyl)-isothioureas which are histamine H2 -antagonists. Two specific compounds of the present invention are S-[6-(N'-methylthioureido)hexyl]isothiourea and...
4161541 Benzhydryl guanidines  
Benzhydryl derivatives of guanidine (Formula I) having blood sugar lowering activity; pharmaceutical hypoglycemic compositions thereof and methods of administering same to hyperglycemic individuals.
4157347 N-cyano isothioureas  
Anti-ulcer agents of the formula ##STR1## wherein R1 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive, and non-toxic pharmaceutically acceptable acid...
4157340 N,N'-[Bis(N-cyanoguanyl)]cystamine derivatives  
Novel compounds of the formula ##STR1## wherein each R1 is the same and is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive, which are useful intermediates...
4154947 Heterocyclic substituted benzylideneaminoguanidines  
This disclosure describes novel substituted benzylideneaminoguanidines useful as anti-hypertensive agents and as diuretics.
4152453 Pharmacologically active compounds and compositions and methods of use  
The compounds are substituted S-(aminoalkyl)isothioureas which are histamine H2 -antagonists. Two specific compounds of the present invention are S-[6-(N'-methylthioureido)hexyl]isothiourea and...
4113776 1-(2-Aminoethyl)-3-(2,6-dihalophenyl)guanidines  
Antihypertensively active thiourea derivatives of the formulas ##STR1## wherein R, R1, R2, R3 and X are as hereinafter described, as well as a method of using a compound of the formula ##STR2##...
4101675 Novel 2,6-di-substituted phenyl-aminoquanidine containing compositions and methods of using same and pharmaceutical compositions containing the same and therapeutic method  
The invention relates to compounds of the general formula: ##STR1## in which one double bond is present between the carbon atom of the quanidine moiety and one of the adjacent nitrogen atoms and R0...
4066695 Thiourea derivatives  
Antihypertensively active thiourea derivatives of the formulas ##STR1## wherein R, R1, R2, R3 and X are as hereinafter described, as well as a method of using a compound of the formula ##STR2##...
4062892 Insecticidal, miticidal and lepidoptericidal active isothiuronium complex acids and free bases  
Compound having the formula ##STR1## wherein R can be selected from the group consisting of benzhydryl and lower alkyls having from about 5 to about 8 carbon atoms; R1 can be selected from the...
4055572 Process for the production of 3-hydroxy-1,2,4-triazole derivatives  
A process for the production of 3-hydroxy-1,2,4-triazole derivatives of formula I ##STR1## wherein R1 and R2 each represent a straight-chain or branched-chain alkyl group having 1 to 6 carbon...
4051101 Halogenated isothiuronium salts as flame retardants  
Compounds of the formula ##STR1## wherein each X is independently selected from a group consisting of hydrogen, chlorine, bromine, alkyl, and haloalkyl, said alkyl containing 1 to 6 carbon atoms...
4028380 Hydrazino-imidazole derivatives  
The invention relates to novel amidino-hydrazone derivatives of the general formula: ##STR1## in which the dotted lines mean one extra bond starting from the (guanidine-)carbon atom to one of the...
4025529 Preparation of nitroketene aminals  
Nitroketene aminals are prepared by treating isothioureas with nitromethane.
4021571 Substituted phenylisothioureas and processes for their preparation and use  
N-[2-(Substituted amido)phenyl]-N'-carbonyl-S-substituted isothioureas bearing an optionally substituted phenoxy, phenylthio, phenylsulfinyl or phenylsulfonyl group in the 4- or 5-position of the...
3983172 Bis-halogen carbonyl anilines and process for the production  
Bis-halogen carbonyl anilines useful in the production of herbicides having the formula ##SPC1##Wherein X is fluorine or chlorine, Y is fluorine, chlorine, fluorocarbonyl, or chlorocarbonyl, Z is...
3959331 Allophanimidate herbicides  
Allophanimidates and carbamates of the formulas ##EQU1## where R1 is hydrogen or alkyl; R2 is alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, benzyl or phenyl optionally substituted; R3 is...
3954837 Substituted allophanates  
Allophanates of the formula: ##EQU1## wherein: THE X's are oxygen or sulfur; R1 is hydrogen, certain organic radicals, or halogen; and R2 and R3 are certain organic radicals,Are useful for the...
3936453 1-Substituted-2-disubstituted aminoquin azolin-4(1h)-ones  
Anti-histaminics of the formula ##SPC1##Wherein R1 is alkyl, alkenyl or phenalkyl, R2 and R3 are alkyl or alkenyl and R and R' are optional are prepared by alkylating or alkenylating a...
3914306 Guanidines  
Novel substituted phenylguanidine compounds and processes for their preparation are disclosed. Their use as anti-hypertensive agents is also revealed.
3904687 Method for production of cationic surfactant  
New type of water-soluble, cationic surfactant having an excellent flocculating effect is obtained by subjecting a raw material aromatic hydrocarbon compound to polycondensation, chlorination, and...
3901944 1,3-Bis(substituted benzylideneamino)guanidines  
The preparation of 1,3-bis(4- and 3,4-substituted benzylideneamino)guanidines and their salts, and of 1-loweralkyl-1,3-bis(4- and 3,4-substituted benzylideneamino)guanidines and their salts and of...
3896175 3,7-Dimethyl-octa-2,6-dienyl-mercaptan  
The preparation and use of the novel 3,7-dimethyl-octa-2,6-dienyl-mercaptan as a new odorant and flavorant is disclosed.
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