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7855228 |
Antibiotics targeting MreB
The identification of MreB as essential for bacterial chromosome segregation provides a new target for antibiotic action. The MreB function is useful in the development of screening assays for new...
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6124351 |
Amino acid derivatives having a nitric oxide synthase inhibiting action
Compounds represented by the general formula (I): ##STR1## (where R1 denotes a hydrogen atom, a straight-chained or branched alkoxycarbonyl group having 1-6 carbon atoms in which the alkyl portion...
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5414028 |
Carbohydrate substituted dibenzo[d,f][1,3,2]dioxaphosphepin stabilizers
Carbohydrate substituted dibenzo[d,f][1,3,2]dioxaphosphepin compounds of formula I ##STR1## where A is a carbohydrate residue are effective stabilizers for polymers processed at elevated...
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5256694 |
Diarylacetylenes, their preparation and their use
Novel diarylacetylenes of the formula I ##STR1## where A, R1, R2, R3, R4, R5 and R6 have the meanings stated in the description, are useful for the treatment of disorders.
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5254335 |
Hair conditioning compounds containing reactive nonionic surfactants and isothiuronium compounds and method of use
Novel isothiuronium surfactant salts are useful as hair conditioning agents. Aqueous composition containing such salts, and method of using the salts are disclosed.
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5114975 |
Anilinophenyl carbodiimides compositions containing them, and the use thereof in pest control
The invention relates to novel substituted aryloxyphenylthioureas, aryloxyphenylisothioureas and aryloxyphenylcarobodiimides of formula I ##STR1## wherein R1 is C1 -C12 alkyl, unsubstituted or...
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5091415 |
Thioformamidines, their preparation and use as medicaments
Formamidine compounds of general formula I ##STR1## in which: R1 represents H or C1-4 alkyl, R2 represents benzoyl, benzyl, or alpha-hydroxybenzyl, the aromatic ring being optionally substituted by...
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5026730 |
Anilinophenylthioureas, compositions containing them, and the use thereof in pest control
The invention relates to novel substituted anilinophenylthioureas, anilinophenylisothioureas and anilinophenylcarbodiimides of formula I ##STR1## wherein R1 is C1 -C12 alkyl, unsubstituted or...
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4965389 |
Phenoxyphenylthioureas phenoxyphenylisothioureas and phenoxyphenylcarbodiimides and use thereof for controlling pests
The invention relates to novel phenoxyphenylthioureas, phenoxyphenylisothioureas and phenoxyphenylcarbodiimides of formula I ##STR1## wherein R1 is C3 -C7 cycloalkyl or C5 -C6 cycloalkenyl, R2 is...
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4954627 |
Process for desulfurization of isothioureas and isothioamides
The present invention is directed to a process for desulfurizing a compound selected from isothioureas and isothioamides comprising heating the compound to be desulfurized in the presence of a...
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4897424 |
Aryloxyphenylthioureas, aryloxyphenylisothioureas and aryloxyphenylcarbodiimides and pesticidal compositions containing them
Novel substituted aryloxyphenyl-thioureas, -isothioureas and -carbodiimides of formula I ##STR1## in which R1 represents C1 -C12 alkyl, C1 -C12 alkyl mono- or poly-substituted by halogen and/or by...
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4748186 |
S-trifluorobutenyl derivatives and pesticidal uses thereof
S-trifluorobutenyl thiocarbonic acid esters of the formula ##STR1## and salts thereof, wherein X is R1 N or S and Y is RS or R3 R2 N; wherein R is a metal or a radical selected from alkyl,...
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4727142 |
Process for the preparation of imidates
The invention relates to a process for the preparation of compounds of the formula I and salts or acid addition compounds thereof ##STR1## in which R denotes hydrogen, (halogenated) alkyl with the...
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4710578 |
Isothiuronium salts
According to the present invention there are provided isothiuronium salts of the general Formula I ##STR1## wherein R1 is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, aralkyl or aryl,...
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4692467 |
N'-cyano-n-tetrahydrownaphthyl-s-methyisothiourea as a growth promoting agent
This invention relates to novel cyanoguanidine compounds and the intermediate N'-cyano-N-(1,2,3,4-tetrahydro-1-naphthyl)-S-methylisothiour
ea. These novel compounds are useful as animal growth...
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4689348 |
Cyanoguanidines useful as animal growth promoting agents
This invention relates to novel cyanoguanidine compounds and the intermediate N'-cyano-N-(1,2,3,4-tetrahydro-1-naphthyl)-S-methylisothiour
ea. These novel compounds are useful as animal growth...
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4649138 |
Pharmaceutical compositions
S-(Aminoalkyl)isothioureas which have immunosuppressant activity. Two specific compounds are 2-(3-dimethylaminopropylthio)-2-imidazoline and N,N'-dimethyl-S-(3-dimethylaminopropyl)isothiourea.
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4647665 |
Preparation of sulphonyliso(thio)ureas and sulphonylisoureas
A process for the preparation of a sulphonyliso(thio)urea of the formula ##STR1## in which R1 represents an optionally substituted radical from the group consisting of alkyl, aralkyl, aryl and...
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4619944 |
Antihypertensive compounds
Provided are antihypertensive compounds of the formula ##STR1## wherein R1, R2, R3, R4, R5, and R6 are hydrogen, alkyl, alkenyl, alkynyl, phenyl-alkyl, or cycloalkyl, and may be the same or...
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4514418 |
2,2-Dihalogeno-3,3-dimethylcyclopropane derivative fungicides
A 2,2-dihalogeno-3,3-dimethylcyclopropylmethyl derivative of the formula ##STR1## in which X and Y each independently is halogen, R is a hydrogen atom or a methyl group, Z is a cyano group, a...
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RE31588 |
Imidazolylmethylthioethyl alkynyl guanidines
Compounds of the formula ##STR1## wherein R1 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive, and nontoxic pharmaceutically acceptable acid addition...
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4421550 |
Herbicidal triazole ureas
Triazole ureas demonstrate utility as agricultural chemicals and in particular as herbicides.
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4419297 |
Preparation of nitriles from formamides
Aliphatic, araliphatic or aromatic nitriles of the formula R--CN are obtained by reacting N-substituted formamides of the formula R--NHCHO with at least the stoichiometric quantity of an acylating...
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4414221 |
Pesticidal 1,2,4-triazole compounds
The compounds of the formula: ##STR1## wherein R1 represents phenyl substituted in at least the 2-position by fluorine, chlorine, bromine or iodine, R2 represents a group R3, --OR3, --SR3 or --NR3...
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4328248 |
Isothiourea derivatives having pesticidal activity
Compounds of the formulae I and II ##STR1## wherein R1, R2 and R3 independently of one another are each hydrogen, C1 -C4 -alkyl, methoxy, halogen, trifluoromethyl or nitro, R4 is hydrogen or...
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4328247 |
Phenoxyphenylisothioureas, production thereof and use thereof in pest control, and phenoxyphenylthioureas as intermediates for the production of the phenoxyphenylisothioureas and use thereof in pest control
The invention relates to N-phenoxyphenylisothioureas of the formula ##STR1## wherein each R1, R2 and R3 is hydrogen, halogen, C1 -C4 alkyl, C1 -C4 alkoxy, trifluoromethyl or nitro, each of R4 and...
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4310539 |
Biocidal isothiourea compounds
Novel biocidal S-aminoalkyl isothiourea compounds have the general structural formula ##STR1## wherein X is halogen; R is a straight or branched chain alkyl radical containing 5 to 20 carbon atoms;...
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RE30457 |
Pharmacologically active compounds
The compounds are substituted S-(aminoalkyl)-isothioureas which are histamine H2 -antagonists. Two specific compounds of the present invention are S-[6-(N'-methylthioureido)hexyl]isothiourea and...
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4161541 |
Benzhydryl guanidines
Benzhydryl derivatives of guanidine (Formula I) having blood sugar lowering activity; pharmaceutical hypoglycemic compositions thereof and methods of administering same to hyperglycemic individuals.
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4157347 |
N-cyano isothioureas
Anti-ulcer agents of the formula ##STR1## wherein R1 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive, and non-toxic pharmaceutically acceptable acid...
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4157340 |
N,N'-[Bis(N-cyanoguanyl)]cystamine derivatives
Novel compounds of the formula ##STR1## wherein each R1 is the same and is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive, which are useful intermediates...
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4154947 |
Heterocyclic substituted benzylideneaminoguanidines
This disclosure describes novel substituted benzylideneaminoguanidines useful as anti-hypertensive agents and as diuretics.
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4152453 |
Pharmacologically active compounds and compositions and methods of use
The compounds are substituted S-(aminoalkyl)isothioureas which are histamine H2 -antagonists. Two specific compounds of the present invention are S-[6-(N'-methylthioureido)hexyl]isothiourea and...
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4113776 |
1-(2-Aminoethyl)-3-(2,6-dihalophenyl)guanidines
Antihypertensively active thiourea derivatives of the formulas ##STR1## wherein R, R1, R2, R3 and X are as hereinafter described, as well as a method of using a compound of the formula ##STR2##...
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4101675 |
Novel 2,6-di-substituted phenyl-aminoquanidine containing compositions and methods of using same and pharmaceutical compositions containing the same and therapeutic method
The invention relates to compounds of the general formula: ##STR1## in which one double bond is present between the carbon atom of the quanidine moiety and one of the adjacent nitrogen atoms and R0...
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4066695 |
Thiourea derivatives
Antihypertensively active thiourea derivatives of the formulas ##STR1## wherein R, R1, R2, R3 and X are as hereinafter described, as well as a method of using a compound of the formula ##STR2##...
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4062892 |
Insecticidal, miticidal and lepidoptericidal active isothiuronium complex acids and free bases
Compound having the formula ##STR1## wherein R can be selected from the group consisting of benzhydryl and lower alkyls having from about 5 to about 8 carbon atoms; R1 can be selected from the...
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4055572 |
Process for the production of 3-hydroxy-1,2,4-triazole derivatives
A process for the production of 3-hydroxy-1,2,4-triazole derivatives of formula I ##STR1## wherein R1 and R2 each represent a straight-chain or branched-chain alkyl group having 1 to 6 carbon...
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4051101 |
Halogenated isothiuronium salts as flame retardants
Compounds of the formula ##STR1## wherein each X is independently selected from a group consisting of hydrogen, chlorine, bromine, alkyl, and haloalkyl, said alkyl containing 1 to 6 carbon atoms...
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4028380 |
Hydrazino-imidazole derivatives
The invention relates to novel amidino-hydrazone derivatives of the general formula: ##STR1## in which the dotted lines mean one extra bond starting from the (guanidine-)carbon atom to one of the...
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4025529 |
Preparation of nitroketene aminals
Nitroketene aminals are prepared by treating isothioureas with nitromethane.
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4021571 |
Substituted phenylisothioureas and processes for their preparation and use
N-[2-(Substituted amido)phenyl]-N'-carbonyl-S-substituted isothioureas bearing an optionally substituted phenoxy, phenylthio, phenylsulfinyl or phenylsulfonyl group in the 4- or 5-position of the...
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3983172 |
Bis-halogen carbonyl anilines and process for the production
Bis-halogen carbonyl anilines useful in the production of herbicides having the formula ##SPC1##Wherein X is fluorine or chlorine, Y is fluorine, chlorine, fluorocarbonyl, or chlorocarbonyl, Z is...
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3959331 |
Allophanimidate herbicides
Allophanimidates and carbamates of the formulas ##EQU1## where R1 is hydrogen or alkyl; R2 is alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, benzyl or phenyl optionally substituted; R3 is...
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3954837 |
Substituted allophanates
Allophanates of the formula: ##EQU1## wherein: THE X's are oxygen or sulfur; R1 is hydrogen, certain organic radicals, or halogen; and R2 and R3 are certain organic radicals,Are useful for the...
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3936453 |
1-Substituted-2-disubstituted aminoquin azolin-4(1h)-ones
Anti-histaminics of the formula ##SPC1##Wherein R1 is alkyl, alkenyl or phenalkyl, R2 and R3 are alkyl or alkenyl and R and R' are optional are prepared by alkylating or alkenylating a...
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3914306 |
Guanidines
Novel substituted phenylguanidine compounds and processes for their preparation are disclosed. Their use as anti-hypertensive agents is also revealed.
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3904687 |
Method for production of cationic surfactant
New type of water-soluble, cationic surfactant having an excellent flocculating effect is obtained by subjecting a raw material aromatic hydrocarbon compound to polycondensation, chlorination, and...
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3901944 |
1,3-Bis(substituted benzylideneamino)guanidines
The preparation of 1,3-bis(4- and 3,4-substituted benzylideneamino)guanidines and their salts, and of 1-loweralkyl-1,3-bis(4- and 3,4-substituted benzylideneamino)guanidines and their salts and of...
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3896175 |
3,7-Dimethyl-octa-2,6-dienyl-mercaptan
The preparation and use of the novel 3,7-dimethyl-octa-2,6-dienyl-mercaptan as a new odorant and flavorant is disclosed.
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