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8501978 Catalytic process for phospho-halogenation of fluorinated alcohols  
A process for manufacturing a polyfluroalkanoyl phosphorodichloridate comprising reacting a polyfluoroalkanol having the general formula Rf—CH2—OH, wherein Rf is a linear or branched C1-C8...
8293724 Therapeutic applications of fatty acid amide hydrolase inhibitors  
Fatty acid amide hydrolase (FAAH) is an enzyme responsible for the degradation of oleamide (an endogenous sleep-inducing lipid) and anandamide (an endogenous ligand for cannabinoid receptors)....
6465687 Thyroid receptor ligands and method  
Novel thyroid receptor ligands are provided which have the general formula (I) where R1 is alkyl of 1 to 4 carbons or cycloalkyl of 3 to 7 carbons; R2 and R3 are the same or different and are...
6031091 Non-nucleotide linking reagents for nucleotide probes  
A versatile reagent with a non-nucleotide monomeric unit having a ligand, and first and second coupling groups which are linked to the non-nucleotide monomeric unit. The ligand can be either a...
6018067 Process of purifying dihydrocarbylchlorothiophosphates  
Crude dihydrocarbylchlorothiophosphate product contaminated with dihydrocarbylpolysulfide and/or dihydrocarbylchlorophosphate is upgraded by treating the crude product with an aqueous hypochlorite...
5585481 Linking reagents for nucleotide probes  
A versatile reagent with a non-nucleotide monomeric unit having a ligand, and first and second coupling groups which are linked to the non-nucleotide monomeric unit. The ligand can be either a...
5401845 Asymmetric aryl phosphites  
Compounds of the formula I ##STR1## in which x is 1, 2 or 3, and, if x=1, R1 is C1 -C30 alkyl, C1 -C18 alkyl substituted by halogen, --COOR2, --CN, --NR3 R4 or by --CONR3 R4, C2 -C18 alkyl which...
5362906 Farnesyl pyrophosphate analogs  
The present invention is directed to farnesyl pyrophosphate analogs which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further...
5344930 Fluorine and phosphorous-containing amphiphilic molecules with surfactant properties  
Compounds of the general formula: ##STR1## are useful as surfactants in the preparation of fluorocarbon emulsions, which can be used as oxygen-carrying blood substitutes, and for many other...
5283350 Aryl esters of phosphonous halides and a process for the preparation thereof  
Aryl esters of phosphonous halides of the formula I ##STR1## in which R' is a phenyl or benzyl radical which bears 1 to 3 substituents, α-methylbenzyl, α, α-dimethylbenzyl, naphthyl or a naphthyl...
5166144 O-halogenocyclobutyl s-alkyl (di)thiophosphoric acid ester-amides and their use as agents for combating pests  
The invention relates to new O-halogenocyclobutyl S-alkyl (di)thiophosphoric acid ester-amides of the general formula (I) ##STR1## in which A represents fluorine or chlorine, B represents hydrogen...
5164383 O-halogenocyclopentyl S-alkyl (di)thiophosphoric-(phosphonic) ester derivatives, processes for their preparation, and their use as pesticides  
O-Halogenocyclopentyl S-alkyl (di)thiphosphoric(phosphonic) acid ester derivatives of the general formula (I) ##STR1## in which R1 represents alkyl, alkoxy or the radical ##STR2## R3 represents...
4981989 Antihypertensive phosphate derivatives and intermediates thereof  
Antihypertensive phosphate derivatives having the following formula are described: ##STR1## wherein X is selected from one or more of: (a) C1 -C24 branched or straight chain alkyl; (b) C1 -C24...
4924024 Phosphorus-containing squalene synthetase inhibitors, new intermediates and method  
Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have the structure ##STR1## wherein Q is ##STR2## or a bond; Z is...
4867907 Aqueous aryl fluorophosphite suspension  
Aryl fluorophosphites have been found to be effective polymer stabilizers and are hydrolytically stable when used to form aqueous suspensions.
4855474 Process for production of phosphorothioic dichlorides  
The aldehyde RCHO is reacted with PCl3 and sulfur monochloride in the presence of chloride ion and under anhydrous conditions to give RCHClO(S)PCl2.
4769364 Pyrimidin-5-yl phosphoric acid ester and thionophosphoric acid ester pesticides  
Pesticidally active novel phosphates of the formula ##STR1## in which R represents hydrogen, alkyl, cycloalkyl, alkoxy, alkylthio, alkylamino, dialkylamino or aryl, R1 represents alkyl, R2...
4670576 Polymerizable phosphorus esters  
Organic esters of chlorine-containing or bromine-containing phosphorus acids and BIS-GMA, as well as organic esters of phosphorus acids having chlorine or bromine bonded directly to phosphorus,...
4391760 S-(Tertiary alkyl) alkylphosphonothioic halides  
Compounds useful as intermediates for insecticides and nematocides having the formula ##STR1## in which R is an alkyl of 1 to 8 carbon atoms, haloalkyl of 1 to 8 carbon atoms, alkenyl of 2 to 8...
4307243 Process of preparing dihalovinyl compounds  
Conversion of esters (R1)(R2)C(C Hal3)OX, X being-P Hal2, --C(O)OR3 or ##STR1## R1, R3 and R4 being optionally substituted hydrocarbyl groups and R2 methyl or hydrogen, with zinc in acetic acid...
4305890 Cyclopropyl dihalo phosphites  
When the reaction of aldehydes with alkali metal trihaloacetates is carried out in the presence of a highly polar aprotic solvent (DMF, DMSO), novel organic alkali metal carbonates, which are...
4285882 Trihalocyclopropyl carbonates  
When the reaction of aldehydes with alkali metal trihaloacetates is carried out in the presence of a highly polar aprotic solvent (DMF, DMSO), novel organic alkali metal carbonates, which are...
4230644 Halogenating reagents  
Novel halogenating agents are derived from triaryl phosphites and chlorine or bromine. They are useful in converting 7-acylamino-3-hydroxy-3-cephem compounds to 7-acylamino-3-halo-3-cephems and...
4182733 Process for preparing phosphoric acid esterhalides  
A phosphoric acid esterchloride is prepared by simultaneously reacting a phosphoric acid ester of formula I ##STR1## wherein R is alkoxy with 1-8 carbon atoms optionally substituted by halogen,...
4172863 Halogen-containing phosphates  
Novel halogen-containing organic phosphorous compounds having the formula ##STR1## wherein N IS THE WHOLE NUMBER 1 OR 2; X represents chlorine or bromine; Z represents oxygen or sulfur; A...
4144290 Production of bromoaryl chlorophosphates  
A process for the preparation of brominated aryl dichlorophosphates or diaryl chlorophosphates of the formula: ##STR1## WHEREIN R each independently is hydrogen, an alkoxy radical or alkyl radical...
4120917 Process for preparing tertiary alkylphosphorodichloridites  
Tertiary alkyl phosphorodichloridites, characterized by the formula: ##STR1## where R1, R2 and R3 may be alkyl having from about 1 to about 4 carbon atoms, aryl having from about 6 to about 8...
4118435 Catalyzed production of phosphorous and phosphonous acid ester chlorides  
In the production of phosphorous or phosphonous acid ester chlorides of the formula Rm (R'O)n PCl3-m-nwherein R and R' are various organic radicals, m = 0 or 1, n = 1 or 2, and m+n = 1 or 2,By...
4085128 Cyclic phosphamide derivatives  
Cyclic phosphamide derivatives of the general formula: ##STR1## [wherein X represents a halogen atom, Y represents a lower alkanesulfonyloxy, and R represents a lower alkyl] being useful as...
4056581 Process for the preparation of phosphorodichloridothiolates  
Certain S-alkyl, -cycloalkyl, -aralkyl, and -aryl phosphorodichloridothiolates are prepared by reacting a sulfenyl chloride, which can be prepared in situ, with phosphorus trichloride and a...
4052485 Perfluoro compounds containing phosphorus  
Perfluoro compounds containing dichloro phosphoryl and/or dichlorophosphoryl radicals are provided which are obtained by reacting perfluoroalkylalkenes with phosphorus trichloride in the presence...
4049754 Tribromoneopentyl phosphorus reactive flame retardants  
Compounds of the formula: [(BrCH2)3 CCH2 O]2 P(O)Rwherein R is a functional group selected from the group consisting of --CHCH2,--CH2 X, --OR'OC(O)CHCH2, --OR'OC(O)C(CH3)CH2, --O(R'O)n H, --OH,...
4034022 Phosphoric esters of polyfluorinated alcohols, and their preparation  
Phosphoric esters of polyfluorinated alcohols are disclosed comprising at least one isomer of phosphorous esters of polyfluorinated alcohols, or one of the derivatives thereof, said esters and...
4016224 Halogenated esters of phosphorus-containing acids  
This invention deals with new phosphorus-containing esters having the formulas ##STR1## wherein Y represents H, CH3 or Cl; R represents a divalent hydrocarbon radical containing one to twenty...
4012465 Alkyl and cycloalkyl methylphosphonofluoridothioates  
1. A compound having the structure represented by the formula: ##STR1## in which R is selected from the group consisting of alkyl groups of 1-5 bon atoms and cycloalkyl groups of 6-9 carbon atoms.
RE28949 2-Chloroethane-(thiono)-phosphonic acid esters  
Novel 2-chloroethanephosphonic acid and 2-chloroethanethionophosphonici acid derivatives of the formula ##EQU1## wherein X is oxygen 2-chloroethanethionophosphonic sulfur; and R is aryloxy,...
3950457 Polymers of halogenated esters of phosphorus-containing acids  
This invention deals with new phosphorus-containing esters having the formulas ##EQU1## wherein Y represents H, CH3 or Cl; R represents a divalent hydrocarbon radical containing 1 to 20 carbon...
3883620 Polyhaloalkyl phosphate esters  
Novel polyhaloalkyl phosphate esters having the formula ##SPC1## Wherein R represents an alkyl group having 1 to 4 carbon atoms, X represents chlorine or bromine, Each Y represents independently...
3875265 O-benzyl-O-ethyl-O-2,4,5-trichlorophenyl phosphorothioate  
New compounds having the generic formula: ##SPC1## Wherein R can be selected from the group consisting of hydrogen, nitro, halogen, alkoxy, alkyl and dioxyalkynyl; R1 can be selected from alkyl...
3856898 SEPARATION OF AMORPHOUS SULFUR AND O,O-DI(C1-C8 ALKYL) PHOSPHORO-CHLORIDOTHIOATE  
Disclosed is a process for treating a mixture comprising O,o-di(C1 -C8 alkyl) phosphorochloridothioate and amorphous sulfur at a concentration up to about one-third of the weight of the...
3780144 HALOGENATED ETHYLENICALLY UNSATURATED PHOSPHATES  
3723580 CONTINUOUS PROCESS FOR MANUFACTURING O,O-DIALKYL-CHLOROTHIOPHOSPHATE  
O,O- is continuously prepared in high yield from phosphorus sulfochloride and sodium lower-alcoholate by continuously supplying to a reaction system 2.0 to 2.3 parts by mole of sodium...
3701818 O-(HALOVINYL) PHOSPHORODICHLORIDOTHIOATES  
3652741 MONO(ALKYL AND ALKENYL)MONO-OMEGA-ALKYNYLARALKYL PHOSPHONATES  
3641224 BROMOALKYL-(DI)-THIOLPHOSPHORIC ACID ESTERS  
3632691 DIOXYPHOSPHINYL METHYLIDES AND DIOXYPHOSPHINYL METHYLENES  
3626036 O-METHYL-O-(2,2 DICHLORO-VINYL) PHOSPHORIC ACID ESTER MONOCHLORIDE AND METHOD OF PREPARATION  
Reacting O,O-dimethyl-0-(2,2-dichloro-vinyl)-phosphoric acid ester with phosphorus pentachloride, or with phosphorus trichloride and chlorine, e.g. at about 40°- 130° C., to form...
3591663 CHLOROALKYL-THIOL-PHOSPHORIC ACID ESTERS AND ESTER AMIDES  
3505433 2-HALOPERFLUORO-1-CYCLOALKEN-1-YLPHOSPHORYL COMPOUNDS  
3489825 PHOSPHONYL CHLORIDES,THIOPHOSPHONYL CHLORIDES AND PROCESS OF MAKING SAME  

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