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5104895 |
Platinum(II) complexes, their preparation and use as anti-tumor agents
Compounds of formula I ##STR1## wherein R 1 and R 2 , that can be the same or different, are hydrogen, alkyl, aryl, aralkyl groups or, if taken together, cycloalkyl groups; A is a carbon atom,...
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5101054 |
Novel fluorine-containing platinum complex
A fluorine-containing platinum complex having anti-tumor activity of the formula: ##STR1## wherein R 1 is a fluorine atom or a trifluoromethyl group, R 2 is a fluorine atom, a hydrogen atom or...
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5089644 |
Preparation of oxamine complexes
A process for making a solution of a complex of an oxamine and a polyvalent paramagnetic metal comprising contacting a solution of the oxamine with (a) the insoluble hydroxide of the polyvalent...
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5077037 |
Novel compositions for magnetic resonance imaging
Methods and compositions for enhancing magnetic resonance imaging in at least a portion of a warm-blooded animal.
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5034553 |
Platinum-(II)-diamine complex, method for the preparation of this compound, preparation with an anti-tumour action which contains this compound and also shaped preparations with an anti-tumour action
The invention relates to a platinum-(II)-diamine complex having the formula et out below: ##STR1## to a method for the preparation of said compound, to a preparation with an antitumour action...
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5034552 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Platinum complexes, process for the preparation thereof, and pharmaceuticals containing these
Platinum complexes of the general formula I [(R 1 NH 2 ) n Pt] q Y m X p (I) in which Y is a phosphonic acid ligand, and the preparation thereof, are described. The platinum complexes...
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5028726 |
Platinum amine sulfoxide complexes
Platinum amine sulfoxide complexes of the formula [PtCl(diam)(R 2 SO)] + X - wherein diam represents a bidentate amine, R is C 3 -C 7 alkyl or cycloalkyl and X - is an anion, exhibit...
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5028724 |
Synthesis of volatile fluorinated and non-fluorinated metal-beta-ketonate and metal-beta-ketoiminato complexes
A process for the vapor-phase synthesis of non-adduct volatile fluorinated and non-fluorinated metal-ligand complexes comprising contacting a β-diketone or β-ketoimine ligand with an inert...
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5008419 |
Novel platinum complex
A platinum complex having the following formula (I) is disclosed, ##STR1## wherein R 1 and R 2 may be the same or different and each independently represents a methyl group or an ethyl group, and...
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4996337 |
Synthesis of cisplatin analogs
This disclosure sets forth a novel process for producing cisplatin analogs which possess antitumor activity.
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4924016 |
Condensed acetoacetic acid ester titanium chelates and process for their preparation
Titanium chelates with 1 to 2 acetoacetic acid ester ligands and one to two alkoxy groups per titanium atom the sum of these ligands and the alkoxy groups being three as well as Ti-O-Ti bridge...
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4921942 |
Organometallic compounds
Organometallic compounds and compositions comprising a metal, an amido carboxyl moiety bonded to the metal, an active moiety bonded to the metal, and at least one modifier moiety sufficient to...
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4909835 |
Acylcyclohexanediones and the oxime ethers thereof with herbicidal and plant growth regulating properties
The invention relates to novel 2-acyl-1,3-cyclohexanediones and the oxime ethers thereof with herbicidal and plant growth regulating properties. The novel 2-acyl-1,3-cyclohexanediones and the oxime...
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4886894 |
Novel Organic platinum complex and process for the preparation thereof
Novel organic platinum complex of the formula: ##STR1## wherein R 1 is hydrogen atom or a lower alkyl group; R 2 is hydrogen atom, a substituted or unsubstituted lower alkyl group, a lower...
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4855467 |
Heat curable epoxy compositions, and amine adducts of cobalt(II) complexes
Certain cobalt(II) complexes such as secondary amine adducts of cobalt(II) acetylacetonate have been found useful as latent catalysts for anhydride-epoxy blends.
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4845124 |
Platinum (IV) complexes
New platinum (IV) complexes are now provided, which exhibit antitumor activity as shown by the tests on mouse leukemia, L-1210 cell in mice. These new platinum (IV) complexes contain...
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4830672 |
Zirconia-based coating composition
A zirconia-based coating composition comprising a mixture obtained by mixing: (a) at least one compound selected from the group consisting of (a') a zirconium compound represented by the general...
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4748254 |
Mixed carboxylato platinum (II) complexes
Novel platinum(II) carboxylatocomplexes of the following general formula: ##STR1## wherein R is tetrahydrofurfuryl or cyclo-C n R" 2n -1, R" is H, an alkyl, hydroxyl, n=3-6; R' is --CH 2 --, --CH...
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4727165 |
Catalytically hydrogenated decomposible molybdenum compounds as oil hydrofining agents
A treated decomposable compound of molybdenum, which has been prepared by the catalytic dehydrogenation of a decomposable compound of molybdenum wherein the molybdenum has a valence state greater...
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4710576 |
Thermochromic arsenic and antimony compounds
There are disclosed compounds having the formula ##STR1## wherein R and R' are selected from the group consisting of (a) substituents having the formula R 1 R 2 R 3 C-wherein R 1 is H or an...
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4687659 |
Diamide-DTPA-paramagnetic contrast agents for MR imaging
Homologs of Diamide-DTPA-Paramagnetic compounds (such as diamido acetyl diethylene triamine triacetic acid) provide excellent contrast agents for magnetic resonance (MR) imaging. The magnetic...
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4687658 |
Metal chelates of diethylenetriaminepentaacetic acid partial esters for NMR imaging
Homologs of Diester-DTPA-Paramagnetic compounds (such as dimethyl acetyl diethylene triamine triacetic acid) provide excellent contrast agents for magnetic resonance imaging (MRI). The magnetic...
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4647680 |
Water-soluble titanium acetylacetonates
The present invention relates to new titanium acetylacetonates. The new compounds contain one or two glycol ether groups bound to the central titanium atom. Their solutions in glycol ethers yield,...
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4617408 |
Modified titanium (IV) acetylacetonates
The present invention relates to new titanium chelates containing both acetylacetone and malonic acid dialkyl ester as chelating agents. The acetylacetone moiety is contained in these new chelates...
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4609746 |
Titanium chelates and preparation of these chelates
Organic titanium chelates which contain only acetylacetone and triethanolamine as ligands and chelating agents and are soluble in glycol ethers are disclosed. The addition of even a small amount of...
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4609745 |
Water-soluble zirconic acid esters
Disclosed are new zirconic acid esters which contain glycol ether moieties as the ester grouping, and which are chelated with one and up to a maximum of two moles of acetylacetone. The new...
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4597800 |
Oxo-aluminum complexes
Oxo-aluminum complexes prepared by reacting a substituted aluminum alkoxide with a molar deficiency of water or carboxylic acid. The complexes are useful in surface coating compositions based on...
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4578487 |
Binding agents containing titanic acid esters for the preparation of coating compositions and refractory bodies, and a method for the preparation of these binding agents
The present invention relates to binding agents for coating compositions which can be used for making foundry molds. The new compositions contain known polymeric titanic acid esters which are...
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4578401 |
Mental complexes having an antineoplastic action, and medicaments containing these complexes
Metal complexes of the general formula I [R 1 (CH 2 ) m C(O)CR 3 C(O)R 2 ] 2 M(OR 4 ) 2 -n X n (I) wherein M denotes titanium, zirconium or hafnium, R 1 ...
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4560783 |
Process for producing aluminum citrate solutions
A process for preparing a stable aqueous solution of aluminum citrate comprising adding citric acid or sodium citrate gradually to an agitated aqueous solution of sodium aluminate under an...
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4560780 |
Method for preparing palladium(II)(hexafluoroacetylacetonate)
Preparation of palladium(II) bis(hexafluoracetylacetonate) and adducts derived therefrom are disclosed, said adducts having the formula Pd(F 6 ACAC) 2 .L n wherein L is a Lewis base selected...
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4558144 |
Volatile metal complexes
Novel adducts of magnesium and zinc β-diketonates with the bidentate ether 1,2-dimethoxyethane are disclosed which exhibit high vapor pressures upon moderate heating, and improved resistance to...
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4552941 |
Polysiloxanes from acyloxysilanes using organo metallic catalyst
Polysiloxanes produced by polymerizing a monomeric silane in the presence of an organo metallic catalyst and the use of the polysiloxanes to react with alkylene-alkyl acrylate copolymers to produce...
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4551544 |
Titanium ester compositions having depressed freezing points
The reaction product obtained by combining (i) a titanate (R 1 O) 4 Ti (particularly tetraisopropyl titanate) with (ii) 2,4-pentanedione and (iii) a substance which is either (a) at least one...
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4544760 |
Reaction products of a difunctional compound and an organo titanate
Reaction products of a difunctional compound and an organotitanate, process for the preparation thereof and the use of these reaction products as crosslinking agents in the preparation of cured...
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4533651 |
Catalysts for olefin oligomerization and isomerization
Catalyst systems for the oligomerization and/or isomerization of olefins which comprise a nickel (II) complex and a co-catalyst. The nickel (II) complex is a square planar species with a trivalent...
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4529552 |
Composite oxyalkoxides and derivatives thereof
Composite oxyalkoxides and their derivatives are novel organometallic compounds which give alkaline earth metal titanates such as barium titanate or strontium titanate by hydrolysis or thermal...
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4518535 |
Preparation of electrically conductive systems from substituted phenalenes, and the products obtained
Air-stable, electrically conductive systems having conductivities greater than 1×10 -3 Ω -1 cm -1 are prepared by reacting a metal cation of an element of sub-group VII, VIII or I of the...
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4482569 |
Platinum (IV)-diamine complexes, a process for the preparation of pharmaceutical compositions and a method of treating malignant tumors in mice
This invention relates to novel-platinum (IV)-diamine complexes, a pharmaceutical composition using the novel complexes and methods of treating malignant tumors in mice using the pharmaceutical...
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4478755 |
Titanate compositions having depressed freezing points
The reaction product obtained by combining (i) a titanate (R 1 O) 4 Ti (particularly tetraisopropyl titanate) with (ii) a lower alkyl acetoacetate (particularly ethyl acetoacetate) and (iii) a...
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4466924 |
Platinum-diamine complexes, a process for the preparation thereof, a process for the preparation of a medicine using such a platinum-diamine complex for the treatment of malignant tumors in mice as well as a medicine thus formed
Platinum diamine complexes of the general formulae ##STR1## wherein R 1 and R 2 independently from each other are a hydrogen atom or a substituted or unsubstituted alkyl, cyclo-alkyl, aryl or...
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4425278 |
Complex compounds, process for their preparation, and their use
A complex compound of a metal salt or metalloid salt and an ansolvo-acid or proton-acid, of the general formula I M n m .X m n .pY.qZ (I) in which M is a m-valent cation...
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4418207 |
Acetylacetoxyalkyl-allyl ethers
Unsaturated acetoacetic acid esters are suitable as comonomers in the polymerization of unsaturated compounds in an aqueous medium. Particularly suitable are acetylacetoxyalkyl-allyl ethers which...
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4415501 |
Alkenylzirconium reagents useful for prostaglandin analog synthesis
Alkenylzirconium reagents of the general structural formula IX, ##STR1## are useful in the syntheses of prostaglandin analogs. In the preceding structural formula J is bromo or chloro, R 1 is...
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4410544 |
Platinum-diamine complexes, a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of malignant tumor in mice
This invention relates to novel platinum-diamine complexes having the formula: ##STR1## wherein R 1 and R 2 independently of each other may be selected from the group consisting of hydrogen, an...
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4404408 |
Complexed compounds, processes for their manufacture and their use
Metal or metalloid salts, ansolvo-acids and proton-acids can be so complexed with 1,2,3-triols, glycerol ethers or glycerol thioethers containing at least 6 C atoms in the molecule that they are in...
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4391757 |
Organic antimony containing stabilizer compositions for halogenated polymers
In accordance with this invention there are provided organic antimony stabilizer compositions effective in stabilizing halogen containing organic polymers against the deteriorative effects of heat...
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4391756 |
Organo-monovalent aurus complex catalysts for the manufacture of olefin oxides
The present invention relates to the oxidation of monoolefins with molecular oxygen to the corresponding olefin oxides, in the liquid phase in the presence of a catalyst comprising an...
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4381360 |
1,3-Dicarbonyl compounds and polyvinyl halide resin compositions containing the same
1,3-Dicarbonyl compounds are provided having the formula: ##STR1## wherein R 1 , R 2 and R 3 are defined in the description as well as metal and organotin enolate salts thereof. The compounds are...
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4351814 |
Hydrotalcites having a hexagonal needle-like crystal structure and process for production thereof
Fibrous hydrotalcites having a hexagonal needle-like crystal structure. The fibrous hydrotalcites are produced by contacting a basic magnesium compound having a needle-like crystal structure and...
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