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7456215 |
Pharmaceutical gallium compositions and methods
Novel pharmaceutical gallium compositions, including gallium complexes having increased oral bioavailablity relative to uncomplexed gallium salts are disclosed. Such compositions are useful in the...
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7279588 |
Dinuclear metal complex and pyrophosphate assay using the same
A novel coordination complex formed by dinuclear metal complexation is provided. The complex is a dinuclear metal complex of a compound, wherein the compound comprises a conjugation ring system...
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7211682 |
Aqueous solution of a sodium salt of HEDTA
The invention pertains to an aqueous solution of a sodium salt xNa + yH + of the chelating compound of formula I:
wherein x=2.1–2.7, y=0.9–0.3, and x+y=3. The invention further pertains...
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7087775 |
Method for preparation of organic chelate
A method for the preparation of organic chelates utilized as ingredients of animal feedstuffs. The organic chelates are passed to the intestines of livestock without decomposition in the stomach,...
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7034172 |
Ferric and acid complex
A ferric and acid complex includes the reaction product of a chelant, iron oxide, a base, and a reaction promoter. The chelant has at least one carboxylic acid functionality. The reaction promoter...
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6992203 |
Metal complexes produced by Maillard Reaction products
A method is disclosed for the formation of metal chelates which are able to remain stable in high alkaline environments when compared to metal chelates produced from a reaction with amino acids....
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6911550 |
Derivatives of seleno-amino acids with improved bioavailability and method for their preparation
Metal L-seleno-alpha-amino acids salts and their use as a bioavailable feed and water ration supplement for domesticated animals such as cattle, pigs and poultry.
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6906213 |
Preparation of aminophosphines
Disclosed is a process for the preparation of phosphine-aminophosphines that are useful in the formation of catalysts useful in carrying out a wide variety of reactions such as asymmetric...
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6906215 |
Powdery s,s-ethylenediamine-n,n′-disuccinic acid iron complex and process for producing the same
There is provided a powdery S,S-EDDS iron complex improved in its caking property. An S,S-ethylenediamine-N,N′-disuccinic acid iron complex, which is crystalline and has an average particle...
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6906212 |
Phosphine-phosphoramidite compounds
Disclosed are novel phosphine-phosphoramidite compounds which may be employed in combination with a catalytically-active metal to effect a wide variety of reactions such as asymmetric...
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6716814 |
Enhancing solubility of iron amino acid chelates and iron proteinates
A method of enhancing the solubility of iron amino acid chelates and iron proteinates is disclosed. This is accomplished by mixing an effective amount of an organic acid solubilizing agent into...
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6710079 |
Composition and method for preparing amino acid chelates and complexes free of interfering complex ions
A composition and method of preparing amino acid chelates and complexes free of interfering ions by blending an amino acid ligand, a calcium oxide and/or hydroxide, and a hydrated metal sulfate...
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6670494 |
Method for preparation of metal organic acid chelates
A method is disclosed where organic acid chelates can be made by reacting an organic acid ligand with a metal compound in a non aqueous environment. The chelate is thereafter recovered by means of...
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6590115 |
Phosphino-aminophosphines
Disclosed are substantially enantiomerically pure bis-phosphine compounds comprising a substantially enantiomerically pure chiral backbone linking two phosphine residues wherein one of the...
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6579904 |
Process for making betaine transition metal complexes for use in animal feed supplements and compositions thereof
Betaine transition metal complexes are formed by: a) reacting a solution including an alkali metal salt of chloroacetic acid with a solution including the transition metal salt to give a solution...
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6515159 |
S,S-ethylenediamine-N,N′-disuccinic acid iron alkali salt and a process for production thereof
An S,S-ethylenediamine-N,N′-disuccinic acid iron alkali salt which contains a lactam compound represented by the following general formula (1): wherein M is an ammonium ion or an alkali metal...
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6472548 |
Process for preparing a complex of a ligand, metal and base
The present invention provides a process for the preparation of a chelant or chelating agent complex of the formula L•B•M. L is an amino acid derivative including two optically active amino...
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6458983 |
Method for synthesizing complexes of platinum with iminoethers and their use as antitumoral drugs and nucleotide-base modifiers
A process for synthesizing complexes of platinum(II) with iminoethers having the formula: [Pt II X 2 (L)(L′)], where X is a monoanionic ligand, L is an iminoether ligand and L′ is an amine...
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6451940 |
Catalysts for olefin polymerizations
Selected nickel complexes of the anions of certain 2-aminotropones are olefin polymerization catalysts. Novel 2-aminotropones and their nickel complexes are also disclosed together with methods of...
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6426424 |
Composition and method for preparing granular amino acid chelates and complexes
Compositions and methods of preparing amino acid chelates and complexes are disclosed and described. Specifically, by (a) blending hydrated metal sulfate salts, amino acid ligands, and reaction...
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6380278 |
Polyurethane salts
A urethane (meth)acrylate metal salt obtained by reacting (A) one or more polyisocyanates, (B) one or more hydroxy functional (meth)acrylates, and (C) one or more metal salt polyols which are the...
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6372932 |
Porous solid products of 1,3,5-benzenetricarboxylate and metal ions
A solid product which is a porous chiral (10,3)-a network of 1,3,5-benzenetricarboxylate molecules of formula (I) where X is H, hydrocarbon, halide, etc, linked through metal atoms. Preferably the...
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6340560 |
Aminopolycarboxylic acid chelating agent, heavy metal chelate compound thereof, photographic additive and processing method
An aminopolycarboxylic acid compound represented by the following formula or analogous thereof: The aminopolycarboxylic acid compound of the present invention can be used as a chelating agent...
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6323354 |
Amino acid chelates from lipoproteins
A method of preparing amino acid transition metal chelates a palatable highly bioavailable source of transition metals for animal nutrition from lipoproteins and transition metal salts. The method...
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6303761 |
Triaminepentaacetic acid compound and paramagnetic metal complex prepared from using the compound as ligand
The present invention provides a triaminepentaacetic acid compound which can be used as a ligand to coordinate to a metal ion to form a paramagnetic metal complex. The paramagnetic metal complex of...
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6300510 |
Iron alkali salt of S,S-ethylenediamine-N,N'-disuccinic acid and process for producing the same
An S,S-ethylenediamine-N,N'-disuccinic acid iron alkali salt which contains a lactam compound represented by the following general formula (1): ##STR1## wherein M is an ammonium ion or an alkali...
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6254850 |
Metal complexes, suitable for use in diagnosis and therapy
The invention relates to diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, containing an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents...
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6177581 |
Mixed-metal chelates and process for the preparation thereof
Mixed-metal chelates represented by the following general formula CaM(III)EDTA(OH).xH 2 O wherein M is a trivalent transition metal and x is 0, 0.5, 1, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, 5, 5.5, 6,...
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6150547 |
Iron-casein complex hydrolyzate and process for the production thereof
This invention provides carbonic acid- and/or hydrogencarbonic acid-iron-hydrolyzates of casein complexes containing a large amount of iron, without causing precipitation after heating their...
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6124258 |
Iron-casein complex and process for preparing the same
Iron-casein complexes and methods for preparation thereof without iron characteristic astringent taste even by heat sterilization and having high iron supplying effect. The iron-casein complexes...
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6114379 |
Bioavailable chelates of creatine and essential metals
A chelate comprised of creatine bonded to an essential mineral selected from the group consisting of Mg, Ca, Cu, Zn, Fe, Cr, Co, Mo, Se and Mn to form a heterocyclic ring. Preferably, the metal is...
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6099824 |
Benzyloxy derivatives of DTPA for MRI
Compounds which can chelate paramagnetic bi- and trivalent metal ions, their chelates with said metal ions and their use as contrast agents in magnetic resonance imaging (MRI), the compounds having...
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6060040 |
Cross-linked polymeric compositions for increasing the MRI contrast in visualising the digestive tract of patients
The invention provides, as contrast signal generators in MR imaging of the digestive tract, paramagnetic metal chelates of novel acrylic compounds of formula C(R 1 R 2 )CR 3 --CO--Z--A (1)...
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6045776 |
Process for the production of metal-complex carboxylic acid amides
The invention relates to a process for the production of metal-complex carboxylic acid amides, characterized in that a metal-complex carboxylic acid mixture that consists of the metal-complex...
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6040432 |
Metal complexes, of DTPA derivatives suitable for use in diagnosis and therapy
The invention relates to diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, containing an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents...
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5973175 |
Hydrothermal process for making ultrafine metal oxide powders
An ultrafine titanium dioxide powder is disclosed that can be produced by hydrothermal treating an amino titanium oxalate composition. Ultrafine titanium dioxide powders are useful in cosmetic and...
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5958372 |
Low viscosity chelating polymers for diagnostic imaging
Disclosed are linear and cross-linked polymers suitable for use as a contrast agent for magnetic resonance imaging containing units comprising the residue of a poly(amine) moiety linked to a...
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5929064 |
Amino acid complexes of cobalt (III) mesoporphyrin IX and cobalt (III) protoporphyrin IX
Amino acid complexes of cobalt (III) mesoporphyrin IX and cobalt (III) protoporphyrin IX are described, as well as methods for the preparation and pharmaceutical composition of same, which are...
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5925487 |
Composition, compound and use
A toner resin composition comprising a toner resin and the metal salt or complex of a carbocyclic hydroxy caboxylic acid containing at least one methylene group optionally substituted by hydroxy or...
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5914095 |
Polychelants containg amide bonds
There are provided polychelants and their metal chelates which are useful in diagnostic imaging and in radiotherapy and which comprise a plurality of macrocyclic chelant moieties, e.g. DOTA...
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5914408 |
Olefin polymerization catalysts containing benzothiazole
A novel metallocene catalyst for the polymerization of olefin (co)polymers is of the general formula: Benzothiazole--E--M--X m L n where, M is a transition metal of Groups 3-10 of the...
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5914097 |
Amino-acyl-type and catecholamine-type contrast agents for MRI
The present invention relates to the preparation of amino-acyl-type and catecholamine-type compounds having multiple carboxylic acid functional groups. Paramagnetic metal (II) or (III) ion chelate...
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5900499 |
Preparation of aminopolycarboxylate-ferric solutions with improved long-term stability
A process for producing a ferric aminopolycarboxylic acid chelate with improved long term stability is disclosed. The process involves heating a mixture of iron oxide, ammonia and...
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5898078 |
Preparation of ferric aminopolycarboxylate solutions having improved stability
A process for preparing a ferric chelate of an aminopolycarboxylic acid wherein an iron-containing material is reacted with an aminopolycarboxylic acid chelant in the presence of a base, which...
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5885548 |
Multiply substituted DTPA derivatives and their metal complexes, and their metal complexes, pharmaceutical agents that contain these complexes, their use in diagnosis and therapy, as well as process for the production of pharmaceutical agents
The invention relates to new, multiply substituted diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, that contain an element of atomic numbers 20-32, 39-51 or...
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5859273 |
Succinic acid derivative degradable chelants, uses and compositions thereof
Polyamino disuccinic acids are effective chelants for use in photography and gas conditioning (both applications preferably involving the polyamino disuccinic acid in the form of a metal,...
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5817292 |
MR imaging compositions and methods
This invention provides compositions useful in MR imaging comprising a polymer comprising units comprising the residue of a chelating agent linked to a poly(alkylene oxide) moiety, the polymer...
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5808013 |
Process for the preparation of N-alkyl substituted metal carbamate solutions and their use
Process for the preparation of N-alkyl substituted metal carbamate solutions characterized in that a water solution of the salt of the metal of which the corresponding carbamate is to be obtained,...
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5804163 |
Contrast agents for magnetic resonance imaging aminosaccharide
A contrast enhancing agent for magnetic resonance images having a chelating agent, which can be bound to metals having at least one unpaired electron. Examples of such chelating agents include...
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5804164 |
Water-soluble lipophilic contrast agents
The present invention relates to water-soluble, lipophilic contrast-enhancing agents, pharmaceutical compositions thereof and methods for diagnostic analysis, particularly NMR or MRI analysis using...
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