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7622590 |
Catalyst complex with carbene ligand
Catalytic complexes including a metal atom having anionic ligands, at least one nucleophilic carbene ligand, and an alkylidene, vinylidene, or allenylidene ligand. The complexes are highly stable...
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7615659 |
Method for the production of compounds containing palladium(0)
The present invention relates to a process for preparing a palladium(0) compound, comprising the reaction of a palladium compound with one or more compounds of the general formula I, II or III in...
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7615636 |
Ruthenium complexes with tridentate heterocyclic ligand and dye-sensitized solar cells using the same
A ruthenium complex is provided. The ruthenium complex is represented by the following Formula (I):
in which, X is a monodentate anion ligand, R 1 , R 2 , R 4 and R 5 are the same or...
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7611733 |
Nanoparticle formulations of platinum compounds
Solid Lipid Nanoparticles of platinum compounds, particularly of antitumor platinum complexes are disclosed. The Nanoparticles of the invention are obtained by a process comprising: a) preparing a...
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7608730 |
Process for the preparation of an anti-tumor platinum (II)—complex
We disclose here processes for making Platinum complex of general formula (I) where in, the conformation of 1,2-diaminocyclohexane is cis, trans-l or trans-d isomer and R 1 and R 2 combinedly...
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7605282 |
Process for the preparation of an oxaliplatin preparation
The present invention relates to an improved process for the preparation of oxaliplatin, the obtained oxaliplatin preparation and its use in cancer therapy.
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7601796 |
Synthesis of hybrid block copolymers and uses thereof
The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.
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7601392 |
Organic-metal precursor material and method of manufacturing metal thin film using the same
Provided are an organic-metal precursor material that can be readily decomposed without reacting with an oxidant, a method of manufacturing a metal thin film using the organic-metal precursor...
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7589225 |
Preparation of platinum(II) complexes
This invention relates to a method for the preparation of a platinum(II) complex containing a neutral bidentate ligand, such as oxaliplatin. The method includes the step of reacting a...
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7589196 |
Amine-substituted biphenyldiphosphines
1,1′-Biphenyl-2,2′-diphosphines having at least one amine substituent in the para position relative to the phosphine group and having the formulae
are ligands for metal complexes which...
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7579373 |
Targeted bisplatinum polyamines as pro-drugs: selective release of platinum
Pro-drug forms of linear polyamine-bridged platinum compounds and methods for their production and use are provided. The polyamine-bridge portion of the compounds is based on spermine or...
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7576126 |
Platinum (II) complexes, preparation and use
The invention relates to a method for the preparation of platinum (II) complexes, in particular dicarboxylatoplatinum (II) complexes containing a neutral bidentate ligand, such as oxaliplatin. The...
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7569606 |
Platinum complexes with mononitrile-containing ligands
Disclosed herein are novel platinum-based complexes possessing one nitrile substituent group (mononitrile) covalently-bonded to the platinum, one or more nitrogen donor ligands capable of forming...
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7566798 |
Platinum complexes and methods of use
The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to...
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7559970 |
Method for producing metal nanoparticles and metal nanoparticles produced thereby
The present invention relates to a method for producing metal nanoparticles and metal nanoparticles produced thereby, in particular, to a method for producing metal nanoparticles used for inkjet...
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7538217 |
Ruthenium complex
The present invention relates to a ruthenium complex, represented by the following formula (I):
RuLL′X 2 (I)
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7534853 |
Rhodium and iridium complexes
The present invention describes novel organometallic compounds which are phosphorescence emitters. Such compounds can be used as active components (=functional materials) in a series of different...
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7462731 |
Processes for the preparation of heterocyclic hydroxyamines and intermediates and catalysts for use therein
A process for the preparation of a compound of Formula (1):
wherein: X is S, O or NR 3 , wherein R 3 is H or an organic group; R is H or an organic group; R 1 and R 2 each independently are...
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7442800 |
Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions
Embodiments in accordance with the present invention provide for a palladium complex characterized by the general formula:
where A is a bidentate monoanionic ligand, NHC is a nucleophilic...
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7413816 |
Organic metallic complex and electroluminescent element using the same
A white or whitish luminescent material for phosphorescence is provided by synthesizing an organometallic complex that is able to convert a triplet excited state into light emission. In particular,...
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7399874 |
Catalyst compound containing divalent tridentate ligand
This invention relates to a catalyst compound represented by the formula:
wherein:
M is a Group 3 to 12 transition metal; each R a is, independently, a hydrogen, a hydrocarbyl group, a...
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7399857 |
Synthesis of organometallic cyclometallated transition metal complexes
A process for forming a tris-cyclometallated complex comprises the step of reacting;
a) an M(I) complex, wherein M represents Rh or Ir, and said complex comprises at least two ligands and...
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7393871 |
Anionic and neutral complexes of ruthenium (II) with nitrogen oxide
A class of anionic and neutral complexes of ruthenium (II) containing nitrogen oxide (NO) and optionally a nitrogen ligand is described; a process for their preparation is also described. The...
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7351846 |
Oxaliplatin with a low content of accompanying impurities and a method for preparation thereof
Oxaliplatin with a low content of accompanying impurities originating from its preparation which contains, by weight, at most 0.01%, preferably less than 0.001%, of alkali metals, at most 0.0005%,...
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7329727 |
Methods and compositions for controlled polypeptide synthesis
Methods and compositions for the generation of polypeptides having varied material properties are disclosed herein. Methods include means for initiating the polymerization of...
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7309796 |
Process for the preparation of 1,2-diaminocyclohexane-platinum(II) complexes
A process for the preparation of diaminocyclohexane-platinum(II)-dicarboxylates has the following steps:
B Conversion of K 2 PtX 2 with 1,2-diaminocyclohexane (DACH) to (2):
C Conversion of...
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7294415 |
Organometallic complex and organic electroluminescent device employing the same
An organometallic complex which includes a carboxylic acid as an ancillary ligand, and an organic electroluminescent device employing the same. The organometallic complex is useful as a...
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7268245 |
Multinuclear platinum compounds
Multinuclear platinum compounds, compositions that include the platinum compounds, methods for making the platinum compounds, and methods for treating cellular proliferative diseases by...
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7268244 |
Monoimine ligand platinum analogs
Disclosed herein are novel platinum-based analogs with a single substituted imine ligand: R 7 RC═NR 8 , wherein the R 7 RC═NR 8 functional group is covalently bonded to the platinum through...
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7259270 |
Supermolecular carboplatin derivatives, their preparation and pharmaceutical composition containing them as active ingredient and applications of the compositions
The present invention relates to a novel class of supermolecular carboplatin derivatives represented by general formula (I), wherein B is a polycarboxylic acid represented by general formula (II),...
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7250526 |
Transfer hydrogenation process and catalyst
A catalytic transfer hydrogenation process is provided. The catalyst employed in the process is a metal hydrocarbyl complex which is coordinated to defined bidentate ligands substituted with at...
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7241913 |
Ruthenium compounds
Ruthenium (II) compounds of formula (I) are useful in the treatment and/or prevention of cancer
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7238372 |
Methods for inhibiting tumor cell proliferation
The subject invention concerns methods for inhibition of STAT biological functions using platinum complexes.
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7208616 |
Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin
The present invention is related to pure cis-diiodo-(trans-L-1,2-cyclohexanediamine) Pt (II) complex, and a process of its preparation. The present invention is further related to the preparation...
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7208611 |
Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
Platinum containing compounds exhibiting cytostatic activity, methods of synthesizing platinum-containing compounds exhibiting cytostatic activity pharmaceutical compositions comprising platinum...
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7205422 |
Volatile metal β-ketoiminate and metal β-diiminate complexes
Metal ketoiminate or diiminate complexes, containing copper, silver, gold, cobalt, ruthenium, rhodium, platinum, palladium, nickel, osmium, or indium, and methods for making and using same are...
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7176327 |
Photoreactive compounds and compositions
The present invention provides a compound of formula (I): Pt IV (N 3 ) 2 X 1 X 2 Y 1 Y 2 , wherein X 1 and X 2 are the same or different and each one is a group NR 1 R 2 R 3 wherein R 1 , R 2 ...
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7166733 |
O,O'-Amidomalonate and N,O-Amidomalonate platinum complexes
The present invention relates to amidomalonate O,O′—Pt and N,O—Pt chelates and methods of preparing them in essentially pure form.
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7163990 |
Polymerization catalyst
A complex of transition metal Ti, Fe, Co, Ni, Cr, Mn, Ta, Rh, Y, Sc, Ru, Pd, Zr, Hf, V or Nb and a mono-, bi-, tri-, or tetra-dentate ligand, wherein at least one of the donor atoms of the ligand...
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7156731 |
Resolution of chiral compounds using aminocyclopentadienyl ruthenium catalysts
A chiral compound, particularly a chiral secondary alcohol, can be efficiently resolved under a mild condition by acylation with an alkenyl acetate in the presence of a novel aminocyclopentadienyl...
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7141691 |
Protein-bound derivatives of platinum complexes containing cyclobutane1, 1-dicarboxyllate ligands
The invention concerns low-molecular platinum complexes containing cyclobutane-1,1-dicarboxylate ligands that contain a protein-binding group.
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7141688 |
Fluorinated dye stabilizers in fluorinated dielectric solvent
The present invention is directed to novel fluorinated dye stabilizers having both high quenching efficiency and solubility in halogenated solvents. These dye stabilizers have shown a significantly...
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7138520 |
Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
In part, the present invention is directed to coordination complexes comprising a therapeutic agent. In one aspect, the subject compositions comprise a platinum metal center and a covalently...
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7129368 |
Platinum carboxylate anticancer compounds
Platinum carboxylate anticancer compounds, pharmaceutical compositions that include the platinum carboxylate compounds, and methods for treating cellular proliferative diseases by administering the...
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7122668 |
Platinum complexes and their use in therapy
The present invention concerns novel platinum complexes in which at least one of the amine ligand is a non-planar heterocyclic aliphatic amine. The platinum complexes may be in a trans or cis...
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7112690 |
Volatile noble metal organometallic complexes
A series of noble metal organometallic complexes of the general formula (I): ML a X b (FBC) c , wherein M is a noble metal such as iridium, ruthenium or osmium, and L is a neutral ligand such as...
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7098355 |
Process for synthesis of organometallic compounds
A method for synthesizing an organometallic compound, which is usefully utilized as a catalyst for manufacturing polyolefins by ring-opening metathesis polymerization of an olefin having strain in...
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7094898 |
Ruthenium compounds, their production and use
A new class of compounds is disclosed that in preferred embodiments relate to Ru-based catalysts suitable for use in olefin metathesis reactions. Such compounds demonstrate high rates of catalytic...
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7084288 |
Organometallic precursor for forming metal film or pattern and method of forming metal film or pattern using the same
The object of this invention is to provide an organometallic precursor for forming a metal film or pattern and a method of forming the metal film or pattern using the same. More particularly, the...
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7060768 |
Polymerization of olefinic compounds
Certain complexes containing ligands having a phosphino group, amino group or an imino group, and a second functional group such as amide, ester or ketone, when complexed to transition metals,...
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