Patents in Class 554/116

Matches 1 - 50 out of 91

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Match	Document	Document Title
1	6342527	Polymeric castor polyesters The present invention deals with the certain castor polyesters which give high gloss when applied to the skin. The ester are the reaction of the hydroxyl group of castor oil with less than one...
2	6030993	2-hydroxypropionic acid derivative and its manufacturing method This invention relates to a novel 2-hydroxypropionic acid derivative and its manufacturing method. Based on its mechanism to inhibit the CPT I, 2-hydroxypropionic acid derivative of this invention...
3	5789608	Phosphorus prodrugs The composition and methods of synthesis of phosphorus prodrugs are described. These methods can be used to convert negatively charged phosphorous bearing drugs into neutrally charged; lipid...
4	5399724	Acyclic terpene compound Novel acyclic terpene compounds useful as intermediates for producing sarcophytol A which have an anti-carcinogenic promotor activity and anti-tumor activity, which compounds are shown by the...
5	5362752	Chemical compounds New cholesterol lowering compounds are formed from the photochemical treatment of zaragozic acid A.
6	5292915	Compounds containing carbonate groups and carbonyl groups and the preparation and use thereof The invention relates to compounds containing carbonate groups and carbonyl groups and having the general formula ##STR1## in which R stands for a C1 -C4 -alkyl radical, an aryl radical, or a...
7	5272069	Method of producing optically active hydroxyesters This invention relates to methods for producing optically active hydroxyesters and also to methods for producing and purifying optically active five-membered ring lactones.More specifically, the...
8	5266713	Aryl alkenoic acid derivatives as leukotriene antagonists Aryl alkenoic acid derivatives, and physiologically acceptable salts thereof, are provided which are potent leukotriene antagonists and may be used for the treatment of circulatory diseases and...
9	5220064	Substituted 4'-hydroxyphenylacetic acid derivatives having antiinflammatory and analgesic activity The present invention is novel compounds, which are derivatives of 4'-hydroxyphenylacetic acid having antiinflammatory activity for the treatment of arthritis, asthma, Raynaud's disease,...
10	5124083	3-substituted and 3,3-disubstituted 4-oxoretinoic acids and their esters There are disclosed 3-substituted and 3,3-disubstituted all-trans-4-oxoretinoic acids and 3-substituted and 3,3-disubstituted 13-cis-4-oxoretinoic acids and their lower alkyl esters.
11	5098613	Anti-inflammatory agents This invention provides benzene derivatives, pharmaceutical formulations of those derivatives, and a method of using the derivatives for the treatment of inflammation in mammals.
12	5053525	Oxo-analogs of mevinolin-like antihyper-cholesterolemic agents Mevinolin-like compounds in which the lactone is opened and the hydroxyl function produced thereby is replaced by an oxo function are potent HMG-CoA reductase inhibitors possessing one less...
13	5008439	Synthesis of 2-(4-hydroxyphenoxy) alkanoic acid esters A method for synthesizing 2-(4-hydroxyphenoxy)alkanoic acid esters by reacting a hydroxyaromatic ketone derivative with a 2-substituted alkanoic acid ester under basic conditions and thereafter...
14	4981619	Process for preparing alpha-hydroxy acids A process for preparing alpha-hydroxycarboxylic acids. An organic halide is reacted with carbon monoxide and a hydrogen donor compound, in the presence of a carbonylation catalyst and an inorganic...
15	4916230	Process for preparing novel N-(acyloxy-alkoxy)carbonyl derivatives useful as bioreversible prodrug moieties for primary and secondary amine functions in drugs This invention relates to a new one-step process for preparation of novel N-(acyloxyalkoxy)carbonyl derivatives useful as bioreversible prodrug moieties for drugs having a primary or secondary...
16	4847303	Tert-butylphenyl compounds useful as anti-inflammatory agents The present invention involves compounds having the structure: ##STR1## wherein: (a) --A1 is selected from the group consisting of --OH, --H, and --O2 CR; (b) --A2 is selected from the group...
17	4570011	Preparation of cyclobutene substituted aromatic hydrocarbons The invention is a process for the preparation of an aromatic hydrocarbon with a cyclobutene ring fused to the aromatic hydrocarbon which comprises, dissolving an ortho alkyl halomethyl aromatic...
18	4403100	(11R)-11-Deoxy-11-alkyl-6-oxo-prostaglandins The present invention provides novel (11R)-11-deoxy-11-alkyl-6-oxo-prostaglandins which are useful for curing and preventing duodenal ulcers and for preventing or treating gastrointestinal cell...
19	T103403	15-Deoxy-16-hydroxy-16-vinyl and cyclopropyl substituted prostanoic acids and congeners This disclosure describes esters having prostaglandin-like activity of 15-deoxy-16-hydroxy-16-substituted-prostanoic acids formed by replacing the hydroxy group of the C1 -carboxylic acid...
20	4349690	9-Deoxy-9-methylene-6-keto-PGE-type compounds The present invention provides novel 9-deoxy-9-methylene-6-keto-PGE derivatives which are useful for platelet aggregation inhibition and gastric cyctoprotection.
21	4338252	1-Descarboxy-1-ketoester (ketoacid)-prostaglandins This disclosure describes certain 11-hydroxy and 11-deoxy-1-ketocarboxylic acid prostanoic acids and derivatives useful as bronchodilators, hypotensive agents, anti-ulcer agents or intermediates.
22	4337353	Novel carboxylic acids, benzoyl phenyl alkanoic acids and use thereof Novel carboxylic acids of the formula ##STR1## wherein Z is an aliphatic hydrocarbon chain selected from the group consisting of --(CH2)n -- and --CHCH--(CH2)n-2 -- where the double bond may be a...
23	4334089	Substituted oxocarboxylic acids, processes for their preparation, their use and medicaments containing them Substituted oxocarboxylic acids of the formula I ##STR1## wherein R1 denotes a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group, a lower alkoxy group or a trifluoromethyl group,...
24	4259250	11a-Homo-PG intermediates for preparing 11a-methano TXA2 compounds The present invention provides novel thromboxane analogs and intermediates. Particularly, the present invention provides novel 11a-homo-PG intermediates for preparing 11a-methano TXA2 compounds.
25	4257973	Process of making acids or esters from unsaturated compounds Water, primary alcohols or secondary alcohols together with carbon monoxide can be added across ethylenic or acetylenic bonds in a wide variety of organic compounds to form acids or esters. The...
26	4250321	1-Descarboxy-1-ketoester(ketoacid)-protaglandins This disclosure describes certain 11-hydroxy and 11-deoxy-1-ketocarboxylic acid prostanoic acids and derivatives useful as bronchodilators, hypotensive agents, anti-ulcer agents or intermediates.
27	4246182	Process for the preparation of omega-hydroxy fatty acids from omega-hydroxy (or acyloxy)-alkyl-γ-butyrolactones Process for preparing omega-hydroxy fatty acids of the formula ROCH2 (CH2)n CH2 CH2 CH2 COOH wherein R is H or acyl, and n is an integer of 0 to 18,by a very simple operation without a trouble of...
28	4236027	Novel 11-alkoxy-9-keto (or hydroxy)-prostenoic acid derivatives and method for preparing same This disclosure describes certain 11-alkoxy-9-keto- (or hydroxy)-prostenoic acid derivatives useful as anti-microbial agents, hypotensive agents, anti-ulcer agents, or as intermediates.
29	4233230	Process for preparing olefins by metathesis of cyclic olefins with acyclic olefins A process for preparing esters and halides is disclosed comprising the step of reacting a cyclic olefin having the formula I ##STR1## wherein R1 and R4 are the same or different from each other and...
30	4229354	Method of preparing alkali metal complex compounds The invention includes novel alkali metal complex compounds (and processes for their preparation) which are useful, inter alia for the hydrogenation of alkali metals at room temperature or below...
31	4223157	6-Keto-ωaryl-PGE1 compounds Prostaglandin E (PGE)-type derivatives and analogs having a 6-ketone feature are disclosed, including processes for preparing them and the appropriate intermediates, said derivatives having...
32	4219662	11-Deoxy-17-phenyl-PGE1 analogs This invention comprises 11-deoxy-17-phenyl-18,19,20-trinor-prostaglandin-type compounds which exhibit prostaglandin-type pharmacological activity, such as lowering blood pressure, inhibiting...
33	4218378	11a-Methano-TXA compounds The present invention provides novel 11a-methano-TXA compounds and intermediates and processs for their preparation. Further provided are methods for using these novel TXA analogs as inhibitors of...
34	4180677	Novel prostaglandins This disclosure describes novel 15-hydroxy prostanoic acid derivatives having anti-ulcer, bronchodilator, and hypotensive activity.
35	4171376	Aryloxyalkyl keto-esters Aryloxyalkyl keto-esters, useful as anti-viral agents, are prepared from an aryloxyalkyl halide and an alkali metal enolate salt of a keto-ester.
36	4161605	ω-Aryl-cis-13-PGE compounds This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical...
37	4160103	ω-Aryl-cis-13-PGA compounds This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical...
38	4157448	ω-Aryl-12,13(e)-didehydro-13,14-dihydro-PGD compounds Prostaglandin analogs with the following cyclopentane ring structure: ##STR1## are disclosed along with intermediates useful in their preparation and processes for their preparation. These analogs...
39	4140863	9,11-Dihalo-PG2 compounds The present invention relates to certain 9,11-dideoxy-PGF-type compounds wherein the C-9 and C-11 carbon atoms are substituted by halogen. In particular, 9,11-chloro-, 9,11-bromo-, and...
40	4126629	Substituted phenoxy-tridecenoic acids/esters This invention relates to aryloxy-, alkoxy-, arylthio-, and alkylthio-11,12-seco-prostaglandins and to processes for their manufacture. These compounds have prostaglandin-like activity and are...
41	4119648	Thromboxane B aldehyde intermediates The present specification provides novel intermediates and novel processes for the synthesis of various side chain and skeletal analogs of Thromboxane B2 (11β-homo-11α-oxa-PGFα). These analogs ar...
42	4116988	16-Phenoxy prostaglandin E1 analogs Prostaglandin-type compounds with a phenoxy or substituted-phenoxy substituent at the C-16 position are disclosed, with processes for making them. These compounds are useful for a variety of...
43	4113963	13,14-Didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGE1 compounds This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical...
44	4111969	5,6-Didehydro-ω-phenoxy-PGE2 analogs This invention comprises certain analogs of the prostaglandins in which there is a triple bond between C-5 and C-6 or C-4 and C-5. Also provided in this invention, are novel chemical processes...
45	4105681	9-Phenyl 5,6-dimethyl-nona-2,4,6,8-tetraeonic acid compounds Novel 9-phenyl 5,6-dimethyl-nona-2,4,6,8-tetraenoic acid,-tetraenal or tetraenol derivatives useful as anti-tumor agents.
46	4099015	2,2-Difluoro-13,14-didehydro-11-deoxy-17-phenyl-18,19,2 0-trinor-PGE2 compounds This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical...
47	4096335	16-Phenoxy prostaglandin B2 analogs Prostaglandin-type compounds with a phenoxy or substituted-phenoxy substituent at the C-16 position are disclosed, with processes for making them. These compounds are useful for a variety of...
48	4096178	13,14-Dihydro-16-phenoxy prostaglandin E1 analogs Prostaglandin-type compounds with a phenoxy or substituted-phenoxy substituent at the C-16 position are disclosed, with processes for making them. These compounds are useful for a variety of...
49	4092339	Process for making polyglycidyl esters Homopolymers and copolymers of glycidyl esters are made by reacting the acids to be esterified with the corresponding polymer of tert.-alkyl glycidyl ether under substantially anhydrous conditions...
50	4087616	16-Phenoxy prostaglandin A2 analogs Prostaglandin-type compounds with a phenoxy or substituted-phenoxy substituent at the C-16 position are disclosed, with processes for making them. These compounds are useful for a variety of...

Matches 1 - 50 out of 91

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