Patents in Class 552/542

Matches 1 - 50 out of 117

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Match	Document	Document Title
1	7067682	6,7-Oxygenated steroids and uses related thereto Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of...
2	7012069	Liver X receptor agonists A compound of formula (I): Each of R 1 , R 2 , R 3 , R 4 , R 4′ , R 5 , R 6 , R 7 , R 11 , R 12 , R 15 , R 16 , and R 17 , independently, is hydrogen, halo, alkyl, haloalkyl, hydroxy, amino,...
3	6686486	Process for effecting allylic oxidation A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of a periodic acid or metal...
4	6555530	Use of estrogens and delta-gonadien-21-Ol-3,20-diones for treating insulin dependent and non-insulin dependent diabetes Analysis of full-blood glucose, serum insulin, serum triglycerides and total serum cholesterol were performed. Glucose levels in blood samples from the oral glucose tolerance test were used for...
5	6423702	PROCESS FOR THE HYDROXYLATION OF AN ACYCLIC OR CYCLIC METHYLENE RADICAL IN THE ALLYLIC POSITION, PHARMACEUTICAL COMPOSITION CONTAINING HYDROXYCHOLESTEROL DERIVATIVES AND UTILIZATION OF SUCH COMPOSITIONS FOR THE PREPARATION OF DRUGS A pharmaceutical composition conatining at least one C3-OH ether or fatty acid monoester of 7B-hydroxycholesterol selected from the group consisting of the ethers or esters of palmitic, oleic,...
6	6388108	Aminosterol compounds and uses thereof Newly isolated aminosterol compounds and pharmaceutical compositions based on the aminosterol compounds are described. Methods for the treatment of various disorders, for example, a microbial...
7	6384251	Process for effecting allylic oxidation using dicarboxylic acid imides and chromium reagents A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of an N-hydroxy dicarboxylic acid...
8	6369247	Process for oxidation of steroidal compounds having allylic groups The instant invention involves a process for oxidizing compounds containing an allylic group, i.e. those containing an allylic hydrogen or allylic alcohol group, to the corresponding enones, using...
9	6274746	Process for allylic oxidation using metal hypochlorite and alkyl hydroperoxide The present invention is directed to a process for effecting the allylic oxidation of an allylic compound having at least two allylic hydrogen atoms on the same carbon atom into corresponding...
10	6239073	Brassinosteroid analogs useful as plant growth regulators Disclosed are compositions and methods for promoting plant growth. The compounds are cyclopropyl-, cyclobutyl-, and cyclopentyl-substituted brassinosteroids having high growth promoting ability....
11	5846962	Anti-obesity agents Anti-obesity agents which comprise 3-ketosteroid compounds as an active ingredient are provided. The anti-obesity agents of the present invention have a high anti-obesity effect with little or no...
12	5834452	1- or 6-hydroxylated steroids A compound of the formula ##STR1## having progestomimetic activity, wherein the substituents are as defined in the specification and compositions of a compound of formula I and an estrogen compound.
13	5637691	Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants Compounds having a broad range of antimicrobial activity generally have a structure including asteroid nucleus with a cationic, preferably polyamine, side chain (X) and an anionic side chain (Y)....
14	RE35517	Method, compositions, and compounds for modulating brain excitability Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, and seizure activity using certain steroid derivatives that act at a newly identified site on the...
15	5591733	Methods, compositions, and compounds for allosteric modulation of the gaba receptor by members of the androstane and pregnane series Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, insomnia and seizure activity using certain steroid derivatives that act at a newly identified...
16	5541348	Bile acids for biological and chemical applications and processes for the production thereof Novel bile acids according to the general formula ##STR1## wherein R 1 represents a hydroxyl group, R 2 and R 3 both represent a hydrogen or a hydroxyl group, or R 2 represents a hydroxyl group...
17	5470574	Active principle isolated from shark tissue A compound of general formula, in substantially pure form, wherein A is a cation. A method for preparation is also disclosed, together with compositions and methods of use thereof.
18	5451575	Method of treating liver dysfunction with 24-R scymnol The present invention relates to 24R-scymnol, including its preparation in substantially pure form and to its use in the treatment of liver dysfunction.
19	5359055	Pregnane derivatives and processes for production thereof There are provided pregnane derivatives represented by formula ##STR1## wherein A 1 represents a hydrogen atom or a hydroxyl group, A 2 represents a substituent such as a hydroxyl group when A 1 ...
20	5264599	Process for reducing cholesterol in animal fats A process is provided for treating an edible animal fat to reduce the content of components having free hydroxyl groups. The process comprises forming a reaction mixture from the fat and a cyclic...
21	5210315	Process for producing α-hydroxyketones A process for producing an α-hydroxyketone represented by formula (I): ##STR1## wherein R 1 represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted aralkyl group, or...
22	5166374	Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them Compounds of general formula I ##STR1## wherein R 1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in α or β configuration, are valuable in human therapy....
23	5096898	Bile acid unsaturated derivatives and pharmaceutical compositions containing them Bile acid derivatives of formula I ##STR1## wherein: R is hydrogen or hydroxy; X is a carboxy or a SO 3 H group, have valuable pharmacologic properties.
24	5030739	Process for the catalytic oxidation of isoprenoids having allylic groups The invention is directed to a process for the catalytic oxidation of an isoprenoid containing at least one allylic hydrogen atom, which process comprises reacting the isoprenoid with oxygen or an...
25	5026883	Derivatives of scymol sulfate A compound of general formula, in substantially pure form, wherein A is a cation. A method for preparation is also disclosed, together with compositions and methods of use thereof.
26	5023250	Steroidal 14α-carboxy-alkyl derivatives as regulators of HMG-COA reductase New 14α-carboxyalkyl sterols are regulators of HMG-CoA reductase and inhibitors of mammalian 14α-methyl demethylase and are useful in lowering serum cholesterol levels and treating fungal...
27	4900477	Novel intermediates and an improved process for producing the compound (3β,5α)-3-hydroxycholest-8(14)-en-15-one An improved process for the large scale production of the compound (3β,5α)-3-hydroxycholest-8(14)-en-15-one is described and two new compounds which have utility as intermediates in synthetic...
28	4891168	Process for producing steroid derivatives A process for producing a steroid compound which is useful as an intermediate for synthesizing plant growth regulators, brassinosteroids, and is represented by the general formula (4): ##STR1## in...
29	4861875	3α,5-cyclo-22,23-dihydroxy-5α-steroid compounds New steroid compounds of the general formula: ##STR1## wherein X is a hydroxyl group and Y is a hydrogen atom, or X and Y, taken together, form an oxo group; each of the two R' radicals is...
30	4790961	Thermally reversible organic solvent gels Stable, thermally reversible gels of organic solvents and a gelling agent having the formula R 1 --(CH 2 ) n --CO 2 --R 2 wherein R 1 is an anthracene analogue or substituted anthracene...
31	4614620	Process for producing i-brassicasterol Disclosed herein is a process for producing i-brassicasterol, comprising charging a mixture of i-sterols derived from a mixture of sterols including brassicasterol into a column packed with a...
32	4604240	Homobrassinolide, and its production and use 22R,23R-Homobrassinolide of the formula: ##STR1## which is useful as a plant growth regulator.
33	4594192	2α-fluorovitamin D.sub.3 The invention provides new derivatives of vitamin D 3 , 2α-fluorovitamin D 3 and the acylates thereof. The compounds are characterized by vitamin D-like activity in their ability to increase...
34	4533772	Process for directly hydroxylating olefins using an osmium-halide catalyst and oxygen oxidant The process for hydroxylating olefins with oxygen in the presence of water, an osmium-halide (e.g., OsBr 3 ) catalyst and transition metal containing co-catalyst (CuBr 2 ) is disclosed.
35	4496779	Process for the hydroxylation of olefins using molecular oxygen, an osmium containing catalyst, a copper co-catalyst, and a cycloaliphatic amine based promoter A process directed to the hydroxylation of olefins by reacting said olefins in the presence of oxygen, water, and a catalyst composition comprising (i) a catalytically active osmium containing...
36	4486613	Process for hydroxylating olefins using an osmium carbonyl catalyst A process for hydroxylating olefins, such as ethylene or propylene, using an oxidant selected from organic hydroperoxides, H 2 O 2 , and oxygen and a catalyst composition comprising at least one...
37	4482763	Process for hydroxylating olefins in the presence of an osmium containing catalyst and organic halogenated hydrocarbon co-catalyst A process for hydroxylating olefins with an organic hydroperoxide and water in the presence of an osmium containing catalyst (e.g. OsO 4 ) and an organic halogenated hydrocarbon co-catalyst (e.g.,...
38	4442037	Water-soluble cholesterol derivative Complexes of albumin combined with organic dibasic acid half esters, such as those of succinic acid and phthalic acid, of 7-hydroxycholesterol are soluble in water and have excellent...
39	4413151	Process for hydroxylating olefins using a supported osmium catalyst A process for hydroxylating olefins using a supported osmium catalyst such as Os 3 (CO) 12 adsorbed on a support, such as MgO, and optionally in conjunction with a co-catalyst such as NaI, is...
40	4351767	Synthesis of 24,25-dihydroxycholesterol This invention relates to the synthesis of steroids which are useful for their biological activity or which may be converted to steroids which have such activity. More particularly, the invention...
41	4304726	Process for the preparation of cholesterol derivatives New organic dibasic acid half esters of 7-ketocholesterol and of 7-hydroxycholesterol represented by the general formula ##STR1## (wherein R 1 is O or --OH and R 2 is a C 1 -C 5 alkylene...
42	RE30538	3-Deoxy-1α-hydroxycholecalciferol 3-Deoxy-1α-hydroxycholecalciferol. The compound is characterized by vitamin D-like activity.
43	4252719	Steroid conversion method and products produced thereby Method for the removal of selected tertiary hydrogen atoms from 5 α-steroids of the cholestane, androstane and pregnane series by chlorination of 5 α-steroids esterified with selected iodoaryl...
44	4234577	Ergostadientriols, compositions containing same, and methods of preparing and using same The present invention concerns ergostadientriols which may be recovered from either the fungus R. oligosporus or the fungus R. oryzae as well as from soybeans which have been fermented with either...
45	4225524	Steroid derivatives and process for preparing the same Steroid derivatives represented by the formula ##STR1## wherein R 1 and R 2 are as defined hereunder which is useful for easily producing a wide variety of active vitamin D, and a process for...
46	4202891	15-Oxygenated sterol compounds and the use of such compounds to inhibit the biosynthesis of sterols 15-oxygenated sterols, having the ability to inhibit the biosynthesis of mevalonic acid, and produce other effects derived from their ability to inhibit the biosynthesis of mevalonic acid, are...
47	4193930	25-Alkyl-3β-hydroxycholest-5-en-7-ones and esters thereof 25-Alkyl-3β-hydroxycholest-5-en-7-ones and esters thereof adapted to lower serum cholesterol and inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase are disclosed.
48	4179452	3α,6α-Dihydroxy-5β-cholestan-24-one derivatives and process for preparing the same 3α,6α-Dihydroxy-5β-cholestan-24-one or its derivative represented by the formula ##STR1## wherein R is as defined hereunder which is a useful intermediate for the production of an active vitamin...
49	4172076	Process for preparing steroidal acids and their intermediate derivatives Steroidal acids of the formula ##STR1## are prepared from steroidal ketones of the formula ##STR2## wherein R 1 is hydrogen; hydroxy; lower alkyloxy; tetrahydropyranyloxy; aryloxy; alkyl;...
50	4116985	Novel method for preparing cholesta-5,7-diene 3β,25-diol and derivatives thereof A new method for synthesizing cholesta-5,7-diene-3β,-25-diol and cholesta-5,7-diene-1α,3β,25-triol has been discovered. ##STR1## wherein R is hydrogen or hydroxy. Various intermediates and...

Matches 1 - 50 out of 117

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