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7601851 Compounds and methods for fluorescent labeling  
Dye reagents useful in labeling biological materials are provided along with methods for their use.
7541454 Compounds and methods for fluorescent labeling  
Compounds useful in the fluorescent labeling of biological materials are provided along with methods for their use and preparation.
7476691 Sulfamate benzothiophene derivatives as steroid sulfatase inhibitors  
The present invention relates to sulfamate benzothiophene compounds of the formula: (I) wherein R 1 , R 2 , R 3 , m and n are as defined in the specification. The invention also relates to...
7449483 Heteroaromate OSC inhibitors  
The present invention relates to heteroaromate OSC inhibitors. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol...
7371872 Prodrugs of excitatory amino acids  
This invention relates to synthetic excitatory amino acid prodrugs and processes for their preparation. The invention further relates to methods of using, and pharmaceutical compositions...
6927298 3,4-alkylenedioxythiophenedioxide compounds and polymers comprising monomeric units thereof  
A 3,4-alkylenedioxythiophenedioxide compound represented by formula (I): in which: A represents a C 1-5 -alkylene bridge; R represents an optionally substituted C 1-24 -alkyl, C 3-18...
6875787 10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure  
The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective...
6756370 Piperidine alcohols  
The invention relates to compounds of formula (I), wherein R 1 , R 2 and A have the meanings given in claim 1, are potent 5-HT 2A antagonists and are suitable for treating psychoses,...
6686390 Compounds having antiinflamatory activity: process for their preparation and pharmaceutical compositions containing them  
The present invention relates to novel heterocyclic compounds of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their regioisomers, their...
6281240 Diarylsulfonylureas for use in treating secretory diarrhea  
This invention provides methods of treating secretory diarrhea or cystic fibrosis in a mammal which comprises administering to a mammal in need thereof an effective amount of diarylsulfonylurea....
6217642 Benzothiophene-2-carboxamide s,s-dioxides for use in anti-fouling applications  
A method and composition for protection against fouling of objects which come into contact with sea water or brackish water comprising a benzothiophene-2-carbomide S,S-dioxide as the essential...
6207686 Endothelin antagonists  
A compound of formula (I), in which: R 1 is lower alkyl, cyclo(lower)alkyl, optionally substituted aryl, optionally substituted heterocyclic group, cyclo(lower)alkyl(lower)alkyl, or...
RE37087 Insecticidal triffluormethyl alkane derivatives  
There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 and A have the meanings given in the description, processes for their...
6194450 Polyaromatic heterocyclic compounds and pharmaceutical compositions comprised thereof  
Novel pharmaceutically/cosmetically-active polyaromatic heterocyclic compounds have the structural formula (I): ##STR1## in which Z is a divalent radical selected from among --O--, --S-- or --Nr'--...
6103912 Photographic products and processes  
A novel class of bridged indicator dyes is disclosed which possess absorption in the infrared region of the electromagnetic spectrum. These bridged indicator dyes are useful as light-absorbing,...
6028069 Heterocyclyl-condensed benzoylguanidines, their production and use as inhibitors of the cellular Na+/H+-antiporter  
Cyclic sulphones of formula (I) are disclosed, in which: R 1 and R 2 each independently of one another stand for H, A, CF 3 , CH 2 F, CHF 2 , C 2 F 5 , Hal, OH, OA, NH 2 , NHA, NA 2 , NO 2 or...
5989451 Compounds and methods for doping liquid crystal hosts  
This invention provides chiral thioindigo compounds for doping smectic liquid crystal hosts, wherein the compounds modulate a chiral bulk property of an induced chiral smectic liquid crystal phase...
5977382 Benzo[b]thiophene compounds, intermediates, processes, compositions, and methods  
The instant invention provides novel benzo[b]thiophene compounds, intermediates, compositions, pharmaceutical formulations, and methods of use.
5849798 Polyaromatic heterocyclic compounds and pharmaceutical/cosmetic compositions comprised thereof  
Novel pharmaceutically/cosmetically-active polyaromatic heterocyclic compounds have the structural formula (I): ##STR1## in which Z is a divalent radical selected from among --O--, --S-- or --Nr'--...
5789436 4,6 Di-t-butyl-5-hydroxy-2,3-dihydrobenzothiophene  
A compound represented by formula (I): ##STR1## wherein R 1 represents a hydrogen atom, a lower alkyl group or an acyl group; R 2 and R 3 , which may be the same or different, each represents a...
5712304 Carboxylic acid amide benzothiophenecarboxamide s-oxides  
New benzothiophenecarboxamide S-oxides of the formula (I) ##STR1## in which R 1 represents optionally substituted alkyl, or represents alkenyl or alkinyl, or represents in each case optionally...
5686471 Dihydrobenzofuran and related compounds useful as anti-inflammatory agents  
A compound having the structure: ##STR1## wherein (a) n is from about 1 to about 3; (b) X is selected from the group consisiting of O, S, SO, or SO 2 ; (c) Y is independently hydrogen or...
5684031 Dihydrobenzofuran and related compounds useful as anti-inflammatory agents  
A compound having the structure: ##STR1## wherein (a) n is from 1 to about 3; (b) X is selected from the group consisting of O, S, SO, or SO 2 ; (c) Y is independently hydrogen or straight,...
5684041 Dihydrobenzofuran and related compounds useful as anti-inflammatory agents  
A compound having the structure: ##STR1## wherein (a) n is from 1 to about 3; (b) X is selected from the group consisiting of O, S, SO, or SO 2 ; (c) Y is independently hydrogen or straight,...
5646121 Pseudopeptides with antiviral activity  
The present invention relates to novel pseudopeptides with antiviral activity of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to a process...
5637719 Reagents for rapid peptide synthesis  
The compounds of the present invention are adaptable as blocking or protecting groups for an amine composition useful in peptide synthesis. The present invention is directed to a method of...
5633231 Valine-containing pseudopeptides with antiviral activity  
The present invention relates to valine-containing, substituted pseudopeptides of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to processes...
5591833 Colorants and intermediates therefor having branched poly(oxyalkylene)moieties, and their manufacture  
Colorants and compositions useful as a fugitive or permanent colorant for a variety of substrates, or as intermediates for their manufacture, and having one or more improved properties of enhanced...
5567827 4-Hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives  
The subject of the invention is 4-hydroxyphenylthio derivatives of general formula: ##STR1## in which: R 1 and R 2 , which are identical or different, each represent hydrogen, a methyl or ethyl...
5547980 Bicyclic sulfones, processes for their production and pharmaceutical agents containing them  
Bicyclic sulfones of the formula I ##STR1## in which Y is a halogen atom, Z is a halogen atom or hydrogen, m and n, that are different and represent an integer 0 or 1, A and B each represent...
5532254 Modulation of calcium channels using benzothiophenes  
A method for modulating calcium channels, increasing the density of calcium channels in vascular and cardiac tissue with no changes in inotropic or pressor response, comprising administering to a...
5482962 Insecticidal N,N'-disubstituted-N-N'-diacylhydrazines  
This invention relates to N,N'-disubstituted-N,N'-diacylhydrazines which are useful as insecticides, compositions containing those compounds and methods of their use. This invention also relates to...
5441722 Short synthesis of 5,6-dihydro-(S)-4-(ethylamino)-(S)-6-[C.sup.3 H.sub.3 ]-4[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide and related non radioactive compounds  
This invention concerns the short synthesis of 5,6-dihydro-(S)-4-(ethylamino)-(S)-6-[C 3 H 3 ]-4H-thieno [2,3-b]thiopyran-2-sulfonamide 7,7-dioxide and related non-radioactive and radioactive...
5428027 Substituted semicarbazone arthropodicieds  
Certain substituted semicarbazones, including all geometric and stereoisomers thereof, agricultural compositions containing them and their use as arthropodicides.
5356926 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo [β]thiophene-2-carboxamides as inhibitors of cell adhesion  
3-Alkyloxy-, aryloxy-, or arylalkyloxybenzo[b]-thiophene-2-carboxamides are described as agents which block leukocyte adherence to vascular endothelium and, as such, are effective therapeutic...
5352781 Process for precursors to calcitriol and related compounds  
The process of the invention comprises reacting a C-22-halo-23,24-bisnorsteroid or C-22-halo-23,24-bisnor-9,10-secosteroid with a nickel complex of an electron withdrawing alkene of the formula...
5328927 Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them  
Compounds of formula (I), and salts and prodrugs thereof ##STR1## wherein Q 1 is halo substituted phenyl; naphthyl; indolyl; benzthiophenyl; benzofuranyl; benzyl; or fluorenyl; . . is an...
5268388 Substituted semicarbazone arthropodicides  
Certain substituted semicarbazones, including all geometric and stereoisomers thereof, agricultural compositions containing them and their use as arthropodicides.
5244893 Benzothiophene-2-carboxamide S,S-dioxides and use  
New compounds of the formula (I) ##STR1## in which R 1 -R 6 have the meanings given in the description, their preparation and use in plant protection, the protection of materials and in the field...
5220027 Sulfone-containing azamethide compounds with a nitrogen-containing aromatic ring of nitrogen containing aliphatic  
This invention provides azamethine compounds represented by the formula (I): ##STR1## wherein X represents ##STR2## R 1 to R 4 represent independently a hydrogen atom, an alkyl group, an alkoxyl...
5208253 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo(b) thiophene-2-carboxamides as inhibitors of cell adhesion  
3-Alkyloxy-, aryloxy-, or arylalkyloxy-benzo[b]thiophene-2-carboxamides are described as agents which block leukocyte adherence to vascular endothelium and, as such, are effective therapeutic...
5208259 Diaryl ether hetrocycles  
The invention concerns a diaryl ether heterocycle of the formula I, or a pharmaceutically-acceptable salt thereof, ##STR1## wherein Ar 1 is optionally substituted phenyl or naphthyl; X 1 is...
5169860 Antitumor compositions and methods of treatment  
This invention provides the use of certain benzofuransulfonamide, benzothiophenesulfonamide, and indolesulfonamide derivatives in the treatment of susceptible neoplasms in mammals. Also provided...
5147889 2-hydroxy-3-(aryl-alkanoyl)-benzo[B]thiophenes and compositions thereof  
Benzo[b]thiophene derivatives of formula ##STR1## their tautomers and salts, in which the index n is 0, 1 or 2, alk is lower alkylene, Ar is phenyl, naphthyl or a monocyclic, five- or six-membered...
5136054 Sulfone-containing azamethine compounds  
This invention provides azamethine compounds represented by the formula (I): ##STR1## (wherein X represents ##STR2## Y represents CO, CC(CN) 2 or SO 2 ; R 1 to R 4 represent independently...
5136049 Heteroarylenemethines and polymers prepared therefrom  
The present invention relates to compounds of formula (I): ##STR1## in which A represents the same or different heteroaryl radicals and substituted heteroaryl radicals; B represents...
5128486 Sulpholenes and processes for their preparation and use  
A sulpholene compound and more particularly 4,4-dimethyl-2,2-dioxo-1,2,4,5,6,7-hexahydro-benzo[c]thiophe ne. These compounds are prepared by bringing myrcene sulphone into contact with a strong...
5112852 Allenyl amines  
The present invention relates to allenyl amines, more specifically, β-ethenylidene(substituted) ethanamines, possessing antihypertensive activity, and having the general formula ##STR1## wherein n...
4636575 Masked curing catalyst for acid-curable compositions  
Compounds of formula II and X ##STR1## wherein X is O, S, SO 2 , methylene, isopropylidene or NCOR 7 where R 7 is alkyl or phenyl, Y is a direct bond or methylene, n is 1 or 2, R 4 is alkyl,...
4595692 7-thiabicycloheptane substituted ethers  
Bicycloheptane substituted ether prostaglandin analogs are provided having the structural formula ##STR1## wherein X is O or ##STR2## and including all stereoisomers thereof. The compounds are...
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