Patents in Class 549/510

Matches 1 - 50 out of 637

Match	Document	Document Title
1	7608710	Cationic surfactants A surfactant comprising a polyether segment including at least one pendant alkoxyfluoroalkyl group, and a cationic substituent defined by one of the formulae: or the substituted derivatives...
2	7605279	Process for producing alicyclic oxetane compound Provided is a production process by which a novel alicyclic oxetane compound which has an oxetane ring, has excellent light transmission in the near ultraviolet region, and is useful as a...
3	7605278	Methods and compositions for converting taxane amides to paclitaxel or other taxanes The invention relates to methods and compositions for converting taxane amides to paclitaxel or other taxanes. In one alternative embodiment, the present invention comprises; (i) selectively...
4	7598290	Cytotoxic agents comprising new C-2 modified taxanes The invention relates to taxanes and to novel cytotoxic agents comprising taxanes and their therapeutic use as a result of delivering the taxanes to a specific cell population in a targeted fashion...
5	7592414	Materials that can be structured, method for producing the same and their use The invention provides low molecular weight or polymeric organic materials in which at least one hydrogen atom is replaced by a group of the formula (A) where R is alkyl group, alkoxyalkyl...
6	7589111	C10 cyclopentyl ester substituted taxanes A taxane having a cyclopentyl ester substituent at C10, a keto substituent at C9, a hydroxy substituent at C2, a 2-thienyl substituent at C3′ and an isopropoxycarbamate substituent at C3′.
7	7585986	Semi-synthesis of taxane intermediates and aziridine analogues and their conversion to paclitaxel and docetaxel A process is provided for the semi-synthesis of taxane intermediates and aziridine analogues of cephalomannine and baccatin III intermediates, and the conversion of such intermediates and analogues...
8	7579491	Process for preparing brevifoliol The present invention provides a process for production of an anticancer taxoid brevifoliol of the formula I from plants belonging to the genus Taxus by first extracting the dried and...
9	7569709	Low pressure carbonylation of heterocycles Heterocycles, e.g., epoxides, are carbonylated at low pressure with high percentage conversion to cyclic, ring expanded products using the catalyst where L is tetrahydrofuran (THF).
10	7563914	Method for preparing paclitaxel The invention concerns a method for preparing paclitaxel characterized in that it consists in starting with 10-deacetyl-baccatine in accordance with a “one-pot” reaction including the following...
11	7550609	Cytotoxic agents comprising taxanes and their therapeutic use A cytotoxic agent comprising one or more taxanes linked to a cell binding agent. A therapeutic composition for killing selected cell populations comprising: (A) a cytotoxic amount of one or more...
12	7550608	Processes for the preparation of docetaxel The present invention provides processes for the production of docetaxel. Docetaxel is produced by protecting the C(7) and the C(10) hydroxy groups of 10-DAB with a bridging silicon-based...
13	7524869	Taxanes having a C10 ester substituent Taxanes having an ester substituent at C(10), a hydroxy substituent at C(7), and a range of C(2), C(9), C(14), and side chain substituents.
14	7524610	Oxetane-containing compound, photoresist composition having the same, method of preparing pattern using the photoresist composition, and inkjet print head including polymerization products of the oxetane-containing compound An oxetane-containing compound, a photoresist composition including the same, a method of preparing patterns using the photoresist composition, and an inkjet print head including polymerization...
15	7507842	Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof The present invention provides cyclic nitro compound, pharmaceutical compositions of cyclic nitro compounds and methods of using cyclic nitro compounds and/or pharmaceutical compositions thereof to...
16	7498452	Taxane derivatives functionalized at the 14-position and a process for the preparation thereof A general process for the functionalization at the 14-position of 13-ketobaccatin derivatives of formula I to give derivatives of formula II wherein the substituents are as defined in the...
17	7495114	Cytotoxic agents containing novel potent taxanes and their therapeutic use Included within the scope of the present invention are potent taxanes and taxanes containing a linking group. Also included is a cytotoxic agent comprising one or more taxanes linked to a cell...
18	7468462	Therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders The present invention is directed to novel compounds according to formulae wherein R 1 , R 2 , R 3 and R 4 are as defined herein. The invention also discloses methods of preparation,...
19	7459281	Docetaxel immunoassay Novel conjugates of docetaxel and novel docetaxel immunogens derived from the 7 and 10 positions of docetaxel and monoclonal antibodies generated by these docetaxel linked immunogens are useful in...
20	7456302	Method for producing pentacyclic taxans Taxan derivatives are produced efficiently and inexpensively, which are useful as oral-administrable antitumor compounds. A compound of formula (1) (wherein R 1 is an alkyl group, an alkenyl...
21	7446126	Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel A process is provided for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel (I) a synthon useful for the preparation of taxanes with antitumour activity, and intermediates for the...
22	7432383	Intermediates for the hemisynthesis of taxanes and preparation processes therefor The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
23	7407691	Photopolymerizable oxetane derivative and liquid-crystal composition containing it Provided are a liquid-crystal compound and a liquid-crystal composition containing the compound, of which the advantages are that they show nematic hybrid orientation on a rubbed TAC substrate,...
24	7381350	Fluorene derivatives and polymers thereof The compound (1) or (2), a composition containing the compound and a polymer obtained by polymerizing the composition. R 1 is fluorine, cyano, alkyl, and so forth; R 2 is hydrogen, alkyl, and...
25	7371875	Cytotoxic agents and methods of use Disclosed are compounds that inhibit proteasomic activity in cells. Also disclosed are pharmaceutical compositions comprising such compounds as well as methods to treat conditions, particularly...
26	7368473	Paclitaxel enhancer compounds One embodiment of the present invention is a compound represented by the Structural Formula (I): Y is a covalent bond of a substituted or unsubstituted straight chained hydrocarbyl group. In...
27	7358378	Processes for the preparation of paclitaxel The present invention provides processes for the production of paclitaxel. Paclitaxel is produced by protecting the C(7) and the C(10) hydroxy groups of 10-DAB with a bridging silicon-based...
28	RE40120	Process for the preparation of taxanes from 10-deacetylbaccatin III A process for the preparation of taxane derivatives by reacting 10-deacetylbaccatin III protected at the 7-and 1-positions with trichloroacetyl groups with a compound of formula and subsequent...
29	7332617	Process for the preparation of docetaxel trihydrate A method to prepare Docetaxel trihydrate using the mixture of acetone and water, which provides the product with good stability, less experiment time, less exposal to light, and avoids purity...
30	7326796	Fluorinated monomers, fluorinated polymers having polycyclic groups with fused 4-membered heterocyclic rings, useful as photoresists, and processes for microlithography The present invention provides novel fluorine-containing copolymers which comprise at least one fluorinated olefin, at least one polycyclic ethylenically unsaturated monomer with a fused 4-membered...
31	7317113	Process for the preparation of the 14β-hydroxy-baccatin III-1,14-carbonate A process for the preparation of 14β-hydroxy-baccatin III-1,14-carbonate useful for the preparation of novel taxane derivatives with antitumor activity.
32	7307176	Inclusion complex of taxol with 2-hydroxypropyl-beta-cyclodextrin The present invention relates to a method for producing a 2-hydroxypropyl-beta-cyclodextrin inclusion complex of taxol, said 2-hydroxypropyl-beta-cyclodextrin having a degree of substitution of 0.4...
33	7300604	Tetrahydroxybenzene tetraester derivative and polymer thereof The invention includes compounds represented by Formula (1): wherein R 1 is an alkyl having 1 to 20 carbon atoms; A 1 and A 2 are a 1,4-cyclohexylene or 1,4-phenylene; X is a single bond,...
34	7288665	Process for selective derivatization of taxanes Processes for the preparation of taxol and other taxanes through selective derivatization of the C(7) and C(10) hydroxyl groups of 10-DAB, particularly a novel process using a new strategy in which...
35	7265231	3-methyl oxetanemethanol derivatives and their use in perfume compositions The present invention relates to new 3-methyl oxetanemethanol derivatives and their use as fragrance chemicals suitable for incorporation in fine fragrances, cosmetics, toiletries and related...
36	7264951	Enhanced production of taxol and taxanes by cell cultures of Taxus species This invention provides methods whereby taxol, baccatin III, and other taxol-like compounds, or taxanes, can be produced in very high yield from all known Taxus species, e.g., brevifolia,...
37	7259268	Method for purification of paclitaxel from paclitaxel-containing materials This invention relates to methods for purification of paclitaxel from a paclitaxel-containing material. The method comprises the following steps: (a) extracting a paclitaxel-containing material...
38	7256299	Chemiluminescent reagents This invention provides for labeling reagents, labeled targets and processes for preparing labeling reagents. The labeling reagents can take the form of cyanine dyes, xanthene dyes, porphyrin dyes,...
39	7256213	Taxanes having a C10 carbonate substituent Taxanes having a methylcarbonate or ethylcarbonate substituent at C(10), a hydroxy substituent at C(7), and a range of C(13) side chain substituents.
40	7247738	Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl) ethoxycarbonyl]-5-oxazolidine carboxylic acids This invention relates to a process for preparation of taxanes comprising subjecting 7,10-diprotected intermediates 7-O-(2-haloacyl)baccatin III 6c or 7,10-O-di-(2-haloacyl)-10-deacetylbaccatin...
41	7241907	Acetone solvate of dimethoxy docetaxel and its process of preparation This invention discloses and claims an acetone solvate of dimethoxydocetaxel or 4-acetoxy-2α-benzoyloxy-5β,20-epoxy-1-hydroxy-7β,10β-dim ethoxy-9-oxotax-11-en-13α-yl...
42	RE39723	Semi-synthetic taxanes with antitumor and antiangiogenetic activities Seco-baccatin III derivatives of formula: wherein R, R 1 -R 4 , R 1 R′ , R 11 R″ , and R 111 R′″ are disclosed herein; pharmaceutical compositions comprising seco-baccatin...
43	7235583	Fatty acid-anticancer conjugates and uses thereof The invention provides conjugates of fatty acids and anticancer agents useful in treating cancer, and compositions and formulations thereof. Methods for using the conjugates also are provided.
44	7230055	Compositions containing oxetane compounds for use in semiconductor packaging Compositions containing oxetane compounds having ester, amide, urea, carbamate, carbonate, or carbonyl functionality one carbon atom removed from the oxetane ring cure at high temperatures are...
45	7230013	C10 carbamoyloxy substituted taxane compositions Compositions comprising a taxane having a carbamoyloxy substituent at C(10), a hydroxy substituent at C(7), and a range of C(2), C(9), C(14), and side chain substituents.
46	7226944	Taxanes having a C7 carbonate substituent Taxanes having a carbonate substituent at C(7), a hydroxy substituent at C(10), and a range of C(2), C(9), C(14), and side chain substituents.
47	7220872	Conversion of taxane molecules The invention provides methods and compositions for reductively deoxygenating an amide group at a C-3′ position of a taxane molecule followed by subsequent intra-molecular acyl migration of an...
48	7202370	Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III A method is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel from 9-dihydro-13-acetylbaccatin III. The preparation of a suitably...
49	7186851	Facile method for synthesizing baccatin III compounds A process for synthesizing a C-7 protected baccatin III compound represented by formula (A), which comprises reacting a 10-deacetylbaccatin III compound represented by formula (B) with a protecting...
50	7186849	C7 ester substituted taxanes Taxanes having an ester substituent at C(7), a hydroxy substituent at C(10), and a range of C(2), C(9), C(14), and side chain substituents.

Matches 1 - 50 out of 637

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