Patents in Class 549/51

Matches 1 - 50 out of 270

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Match	Document	Document Title
1	8133998	Bicyclic pyrimidine derivatives as calcium channel blockers Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a...
2	7932404	2,2-bipyridine ligand, sensitizing dye and dye sensitized solar cell A dye sensitized solar cell, comprising a-heteroleptic polypyridil complex of Ru, Os or Fe. The donating ligand has an extended conjugated n-system increasing the light absorbance and keeing the...
3	7872024	Benzothiophene hydroxamic acid derivatives with carbamate, urea, amide and sulfonamide substitutions The present invention relates to a novel class of hydroxamic acid derivatives carbamate, urea, amide and sulfonamide substitutions. The hydroxamic acid compounds can be used to treat cancer. The...
4	7834034	Benzothiophene derivatives The present invention relates to a novel class of benzothiophene amide derivatives. The hydroxamic acid compounds can be used to treat cancer. The benzothiophene amide compounds can also inhibit...
5	7655641	Sulfonamide derivatives as PPAR modulators The present invention is directed to a compound of Formula (I): and pharmaceutically acceptable salts, solvates, hydrates or stereoisomers thereof, which are useful in treating or preventing...
6	7655680	Thiazole compound and use thereof Thiazole compounds for inhibiting the activity of phosphodiesterase 4, the production of tumor necrosis factor alpha, and the production of interleukin 4. The compounds of the invention are...
7	7592375	Ion conductive polymers and imide monomers Disclosed herein is an ion conductive polymer comprising a unit represented by Formula (1) below: —SO2[N−SO2(M+)]X1- (1) wherein X1 is an integer greater than 1, and M+ is H+ or Li+. Further dis...
8	7534475	Liquid crystal compound comprising two condensed and substituted rings A new liquid crystal compound comprises two condensed and substituted rings. The ring preferably is a five-membered heterocyclic ring. The heterocyclic ring is preferably condensed with benzene...
9	7531672	Preparation of heterocyclic ketones The present invention relates to a process for preparing heterocyclic ketones of the formulae (I) and (la), by reacting a heterocyclic compound of the formula (II), with an α, β-unsaturated c...
10	7425631	Compounds and methods of use Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically...
11	7417064	3-aryloxy/thio-3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake There is provided a compound of formula (I) wherein A is selected from —O— and —S—; X is selected from C2-C8 alkyl, C2-C8 alkenyl, C3-C8 cycloalkyl and C4-C8 cycloalkylalkyl, each of which may be ...
12	7410996	3-aryloxy/thio-2,3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake There is provided a compound of formula (I) wherein A is selected from —O— and —S—; X is selected from phenyl optionally substituted with up to 5 substituents each independently selected from ha...
13	7399781	N-substituted benzothiophenesulfonamide derivatives The present invention relates to an N-substituted benzothiophenesulfonamide derivative or a pharmaceutically acceptable salt thereof and applications thereof. Furthermore, it provides an agent for...
14	7375130	Antidiabetic compounds comprising benzofuran and benzothiophene derivatives The invention relates to compounds of the general formula (I) below: in which R1, R2, R3, R4, R5, R6 and X are as defined in claim 1. These compounds can be used in the treatment of pathologies...
15	7371774	Benzofurans and benzothiophenes The invention relates to compounds of the general formula (I) below: in which R1, R2, R3, R4, R5, R6 and X are as defined in claim 1. These compounds can be used in the treatment of pathologies...
16	7271264	Pentacyclic oxepines and derivatives thereof, compositions and methods The present invention provides a compound of the formula (I) wherein R1 is —H, —OH, —O(C1-C4 alkyl), —OCOC6H5, —OCO(C1-C6 alkyl), or —OSO2(C2-C6 alkyl); R0, R2 and R3 are each independent...
17	7270871	Dispersions and films comprising conducting polymer for optoelectronic devices A dispersion, and a film and optoelectronic devices formed from the dispersion are provided. The dispersion comprising conducting polymer containing particles having a particle size of less than...
18	7244763	Compounds that modulate PPAR activity and methods of preparation This invention relates to compounds that alter PPAR activity. The invention also relates to pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising...
19	7157491	Aryl-carbaldehyde oxime derivatives and their use as estrogenic agents This invention provides estrogen receptor modulators having the structure where R1–R5 are as defined in the specification; or a pharmaceutically acceptable salt thereof.
20	7084136	Drug composition antagonistic to both PGD2/TXA2 receptors A compound of the formula (I): wherein A is alkylene optionally having an unsaturated bond; R is —C(═O)—R1; R1 is hydroxy or the like; m is 0 or 1; p is 0 or 1; X1 and X3 are each indep...
21	7037932	Heteroaryloxy 3-substituted propanamines as serotonin and norepinephrine reuptake inhibitors There is provided a heretoaryloxy 3-substituted propanamine compound of formula (I): wherein A is selected from —O— and —S—; X is selected from phenyl optionally substituted with up to 5 substit...
22	7019024	Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof.
23	6921827	Process for preparing 3-aryl-benzo{b} thiophenes The present invention relates to a process for preparing a compound of formula (I): which includes cyclodehydrating a compound of formula (II): in the presence of an acid activated clay or acid...
24	6872730	Substituted benzofurans and benzothiophenes, methods of making and methods of use as integrin antagonists The present invention relates to novel substituted benzofurans and benzothiophenes compounds that are antagonists of alpha V (αv) integrins, for example αvβ3 and αvβ5 integrins, their phar...
25	6784299	Substituted aromatic ethers as inhibitors of glycine transport This invention relates to a series of substituted aromatic ethers of the formula I wherein ring A and X and Y are defined as in the specification, that exhibit activity as glycine transport...
26	6730670	7-phenyl-benzo&lsqb b&rsqb thiophen amide derivatives A compound of the formula Compounds of formula I have a good affinity to the A2A receptor and are useful for the treatment of diseases mediated by this receptor.
27	6720423	Dihydrobenzofuran and dihydrobenzothiophene 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors Compounds of the formula where the variables have the meaning defined in the specification, are specific or selective agonists of RXR retinoid receptors.
28	6713505	spla2 inhibitors A class of novel benzo(b)thiophene is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of Inflammatory Diseases such as septic...
29	6699860	Di-substituted aminomethyl-chroman derivative beta-3 adrenoreceptor agonists This invention is related to novel di-substituted aminomethyl chroman derivatives which are useful in the treatment of beta-3 receptor-mediated conditions.
30	6653340	Compounds useful in the complement, coagulat and kallikrein pathways and method for their preparation The present invention is concerned with new compounds, and particularly those having a fused bicyclic ring substituted with an amidine moiety. These compounds are each potent inhibitors of Factor D...
31	6620947	Compounds for use in 11-oxa prostaglandin synthesis Novel processes and intermediates useful in the preparation of 11-oxa prostaglandin analogs are disclosed.
32	6555697	Method of preparing a benzofuran or benzothiophene compound The invention concerns a novel method for preparing a benzofuran or benzothiophene compound by cyclizing an aromatic compound bearing a side-chain comprising at least two carbon atoms, one of the...
33	6515015	Antidiabetic agents based on aryl and heteroarylacetic acids The instant invention is concerned with aryl and heteroaryl acetic acid and oxyacetic acid compounds, which are useful as antidiabetic compounds. Compositions and methods for their use in the...
34	6495702	Process for preparing 5-hydroxybenzo &lsqb b&rsqb thiophene-3-carboxylic acid derivatives Processes for producing benzothiophenecarboxylic acid derivatives of the formula (I), which are useful as starting materials for producing drugs, are disclosed. Also disclosed is a process for...
35	6472531	Synthesis of 3-&lsqb 4-(2-aminoethoxy)-benzoyl&rsqb -2-aryl-6-hydroxybenzo&lsqb b&rsqb thiophenes The present invention is directed to chemical processes for preparing 2-aryl-6-hydroxy-3-[4-(2-aminoethoxy)benzoyl]benzo[b]-thioph enes. The present invention is also directed to crystalline...
36	6465662	Process for preparing benzothiophenecarboxamide derivatives A process for preparing a compound having PGD2 antagonism represented by the formula (I), or a pharmaceutically acceptable salt or hydrate thereof, which process comprises reacting an amino alcohol...
37	6440958	Acrylic and propionic acid compounds, intermediates, processes, compositions, and methods This invention is directed to a class of acrylic and propionic acid compounds and their use in the treatment of post-menopausal symptoms and restenosis. In other embodiments, the invention is...
38	6441196	Processes and novel intermediates for 11-oxa prostaglandin synthesis Novel processes and intermediates useful in the preparation of 11-oxa prostaglandin analogs are disclosed.
39	6432983	Benzothiophene compounds intermediates processes and methods of use The instant invention provides compound of formula I wherein:R1 is —H, —OH, —O(C1-C4 alkyl), —O—CO—(C1-C6 alkyl), —O—CO—O(C1-C6 alkyl), —O—CO—Ar in which Ar is optionally substituted phenyl, or ...
40	6403172	Benzothiophenes, and their use in liquid-crystalline mixtures Benzothiophene derivatives of the formula (I) are used as components of liquid-crystal mixtures where the symbols and indices have the following meanings:X1 and X2, independently of one another,...
41	6353014	15-ketal postaglandins for the treatment of glaucoma or ocular hypertension A method of treating glaucoma or ocular hypertension in a patient, which comprises administering to the patient a pharmaceutically effective amount of a compound of formula I:
42	6350909	Methoxymino-phenylacetamide derivatives and their utilization as pesticides The invention relates to new imides, to a plurality of processes for their preparation and to their use as fungicides.
43	6329421	Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2 The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a...
44	6320060	Process for producing 5-hydroxybenzo[b] thiophene-3-carboxylic acid derivatives Benzothiophenecarboxylic acid derivatives of the formula (I) which are useful as starting materials for producing drugs, and a process for preparing 5-hydroxybenzo[b]-thiophene-3-carboxylic acid...
45	6291685	Methods for the preparation of 4-hydroxybenzothiophene The present invention is concerned with a novel process for the preparation of the hydroxybenzothiophene of formula I ##STR1##comprising cyclocarbonylation of a compound of formula II...
46	6288105	Antithrombotic agents This application relates to novel compounds of formula I (and their pharmaceutically acceptable salts), as defined herein, processes and intermediates for their preparation, pharmaceutical...
47	6265428	Substituted phenyl compounds and derivatives thereof that modulate the activity of endothelin Methods, compositions, and compounds for modulating the activity of an endothelin peptide are provided. The methods use compositions that contain compounds of formula (1): ##STR1##where X and Y are...
48	6225336	Compounds having [2.2.1] bicyclo skeleton This invention provides novel compounds which are dual antagonistic to TXA2 and PGD2 receptors and the pharmaceutical compositions containing them. They are useful for treating, for example,...
49	6214859	Ethylamine derivatives Ethylamine derivatives of the formula (I): ##STR1## (wherein R1 is hydrogen, hydroxyl, lower alkoxy or halogen; R2 is alkyl having 2 to 5 carbon atoms; R3 is hydrogen, alkyl having 2 to 5 carbon...
50	RE37087	Insecticidal triffluormethyl alkane derivatives There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1##in which R1, R2, R3, R4 and A have the meanings given in the description, processes for their preparation...

Matches 1 - 50 out of 270

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