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7638256 |
Fluorinated cyclic structure-bearing silicon compounds and silicone resins, resist compositions using the same, and patterning process
Silicon compounds having fluorinated hemiacetal structure are provided. Silicone resins having the same structure have an appropriate acidity to enable formation of a finer pattern by minimizing...
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7553867 |
Furan or thiophene derivative and medicinal use thereof
The present invention provides a compound represented by the formula (I):
[wherein R is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, p is 0, 1 or...
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7553970 |
Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives
The invention relates to a process for preparing enantiomer-enriched 3-heteroaryl-3-hydroxypropanoic acid derivatives and 3-heteroaryl-1-aminopropan-3-ols, and to their use.
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7507840 |
Acceptor compounds useful for making hyperpolarizable organic chromophores
Acceptor compounds useful for making hyperpolarizable organic chromophores having a π-donor conjugated to a π-acceptor through a π-bridge.
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7396843 |
5′-carbamoyl-1,1′-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors
Compounds of formula (I):
or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
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7183297 |
Biphenyl-derivatives as p38-kinase inhibitors
Compounds of formula (I):
or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
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7144909 |
Phenoxy substituted benzocondensed heteroaryl derivatives as thyroid receptor ligands
This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders,...
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7132001 |
3-aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers
The object of the present patent application are 3-aminophenol derivatives of formula (I) or the physiologically compatible, water-soluble salts thereof
and colorants based on a...
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7128764 |
M-aminophenol derivatives and coloring agents containing them
The object of the present patent application are 3-aminophenol derivatives of formula (I) or the physiologically tolerated, water-soluble salts thereof
wherein R denotes a heterocyclic aromatic...
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7122061 |
Agents for dyeing keratin fibers, containing 4-aminobiphenyl-3-ol-derivatives
The present invention has for an object compounds of formula (I) and colorants containing these 4-aminobiphenyl-3-ol derivatives of general formula (I) for dyeing keratin fibers, particularly hair,...
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7098201 |
Heteroaromatic derivatives having an inhibitory activity against HIV integrase
A compound of the formula (I):
wherein X is hydroxy, protected hydroxy or optionally substituted amino; Y is —COOR A wherein R A is hydrogen or ester residue, —CONR B R C wherein R B ...
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7091051 |
Chemiluminescence method of 1,2-dioxetane and composition for chemiluminescence
A chemiluminescence method characterized in that when a 1,2-dioxetane derivative of the formula 1:
wherein each of R 1 , R 2 , R 3 , R 4 and R 5 which are independent of one another, is a...
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7087599 |
Estrogen receptor modulators
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen...
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7019154 |
Process for the production of 5-benzyl-3-furfuryl alcohol
Synthesis process of 5-benzyl-3-furfuryl alcohol including the reduction reaction with NaBH 4 or with sodium dihydro bis-(2-methoxyethoxy)aluminium hydride of...
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7015359 |
Vapor phase catalytic process for simultaneous furfural hydrogenation and cyclohexanol dehydrogenation
The present invention provides a catalytic process for the synthesis of furfuryl alcohol and cyclohexanone simultaneously over a copper based catalyst in vapour phase conditions by hydrogenation of...
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7012094 |
Substituted furans and furanones for the treatment of inflammation
A class of 3,4-diaryl substituted thiophene, furan and pyrrole derivatives and analogs thereof, pharmaceutical compositions containing them and methods of using them to treat inflammation and...
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6933091 |
Photoconductor for electrophotography and quinomethane compound
A highly sensitive positively charged type electrophotographic photoconductor includes an organic compound that transports electrons efficiently, improving light emission efficiency. The...
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6903086 |
Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derivatives as IP antagonists
This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula I:
wherein G 1 is selected from the group consisting of a, b 1 and b 2 ,...
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6897324 |
Process for the preparation of 11-oxaprostaglandins and intermediates therein
For the preparation of an 11-oxaprostaglandin such as [2R,(1E,3R),3S,(4Z),4R)]-7-{tetrahydro-2-[4-(3-chlorophenoxy
)-3-hydroxy-1-butenyl]-4-hydroxy-3-furanyl}-4-heptenoic acid and its ester...
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6887871 |
Use of phenylheteroakylamine derivatives
There is disclosed the use of a compound of formula (I) wherein R 1 , R 2 , X, Y, V, W and Z are as defined in the specification, and pharmaceutically acceptable salts, enantiomers or racemates...
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6878723 |
LTA4 hydrolase inhibitors
The invention concerns compounds inhibiting LTA 4 hydrolase of formula (I). The invention also concerns their therapeutic, in particular anti-inflammatory, applications.
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6840965 |
P-aminophenols and colorants containing said compounds
The object of the invention are p-aminophenol derivatives of general formula (I) or physiologically tolerated, water-soluble salts thereof
and oxidative coloring preparations based on a...
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6812354 |
Process for preparing 3-methyltetrahydrofuran
Disclosed is a process for the preparation of 3-methyltetrahydrofuran (MeTHF) from 3-(hydroxymethyl)tetrahydrofuran (HOMeTHF) or 3-formyltetrahydrofuran (FTHF) by contacting HOMeTHF or...
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6686348 |
Metalloprotease inhibitors
A compound of formula (I): wherein: R 1 represents hydrogen, halogen, alkyl or alkoxy, X represents oxygen, sulphur or NR wherein R represents hydrogen or alkyl, A represents any one of the...
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6677353 |
Substituted N-phenyl-N-heteroaralkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity
The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer...
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6624316 |
Method for obtaining 2-bromo-5-(2-bromo-2-nitrovinyl)-furan
The present invention refers to a new procedure for obtaining and purifying 2-bromo-5-(2-bromo-2-nitrovinyl)-furan in one reaction step starting with 2-nitrovinylfuran, and maintains high indexes...
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6599924 |
2-hetaryl-3,4-dihydro-2H-pyrrole derivatives
The invention relates to novel 2-hetaryl-3,4-dihydro-2H-pyrrole derivatives of the formula (I) in which Hetaryl represents substituted heterocyclyls and Ar represents substituted phenyl, to a...
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6599934 |
3,4-diaryl thiopenes and analogs thereof having use as antiinflammatory agents
A class of 3,4-diaryl substituted thiophene, furan and pyrrole derivatives and analogs thereof, pharmaceutical compositions containing them and methods of using them to treat inflammation and...
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6586461 |
Prenyl transferase inhibitors
Farnesyl diphosphate analogs, specifically the 3-substituted alcohol precursors of the diphosphate analogs, 3-allylfarnesol and 3-vinylfarnesol, are potent inhibitors of mammalian protein...
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6541647 |
Methods of synthesis of substituted tetrahydrofuran compound
The invention includes inter alia new methods for preparation of the pharmaceutically active compound 2-(4-fluorophenoxymethyl)-5-(4-N-hydroxyureidyl-1 -butynyl)-tetrahydrofuran and precursors...
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6541475 |
α, β-unsaturated sulfones for treating proliferative disorders
α, β-Unsaturated sulfones of the following formulae are provided, which are useful as antiproliferative agents, including, for example, anticancer agents:
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6521765 |
Process for the preparation of 3-methyltetrahydrofuran
Disclosed is a process for the preparation of 3-methyltetrahydrofuran (MeTHF) from 3-(hydroxymethyl)tetrahydrofuran (HOMeTHF) by contacting HOMeTHF with hydrogen in the presence of an acidic,...
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6518440 |
Hydroxymethylfurfural derived from cellulose contained in lignocellulose solids
A method to produce hydroxymethylfurfural from cellulose contained within lignocellulose solids is disclosed. Hemicellulose contained in lignocellulose solids is converted to furfural....
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6462207 |
Polyethylene glycol diene derivatives
A series of polyethylene glycol derivatives possessing a diene moiety has been prepared and characterized. The reactivities of these derivatives in various Diels-Alder reactions have been...
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6452013 |
Gastrokinetic monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
The present invention of compounds of formula (I) a stereochemically isomeric form thereof, an N-oxide form thereof or a pharmaceutically acceptable acid addition salt thereof, R 1 is C 1-6...
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6448416 |
Electron acceptors for polymeric thin film waveguide media
The present invention is directed to dicyanomethylenedihydrofuran-based electron acceptors which can be used in the preparation of polymeric thin films for waveguide media, and methods of making...
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6420392 |
Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes are disclosed that reduce the chemotaxis and respiratory burst leading to the formation of damaging oxygen...
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6420419 |
L-ascorbic acid 2-phosphate zinc salt and process for manufacturing the same
L-Ascorbic acid 2-phosphate zinc salt and a salt hydrate thereof having excellent solubility and exhibiting good stability even under weakly acidic conditions. Also disclosed is a process of...
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6369102 |
Substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
Substituted tetrahydrofuran analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
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6355814 |
Process for the preparation of 3-hydroxymethyl tetrahydrofuran
The present invention relates to a catalytic process for the preparation of 3-hydroxymethyl tetrahydrofuran of formula IV with hydroformylation as one of the key steps. The process comprises...
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6307067 |
Palladium and boron co-catalyzed addition of oxygen nucleophiles to vinyl epoxides
Nucleophilic oxygen species, such as primary alcohols, carboxylates, and water, are added to vinyl epoxides in a highly regioselective and enantioselective manner, providing a convenient route to...
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6271425 |
Process for producing alcohols
A novel process for producing alcohols, characterized by reacting an organic halide represented by the formula R--X (wherein R means an organic residue and X means a halogen atom) with oxygen...
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6268513 |
Phosphine ligands metal complexes and compositions thereof for cross-coupling reactions
The present invention discloses new efficient processes for various bond forming reactions, including Suzuki reactions and aryl aminations. Organic compounds (e.g., ligands), their metal complexes...
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6225487 |
Ancillary ligands and metal complexes, catalysts and compositions using same and methods of testing
A new ligand having a backbone comprised of PCCC, where the last carbon atom is sp 3 hybridized can be combined with a metal or metal precursor compound or formed into a metal-ligand complex to...
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6191292 |
Precursors of the A-ring of vitamin D and method and intermediates for the preparation thereof
The invention relates to precursors of the A-ring of vitamin D, of the formula (I): ##STR1## in which A, R, R 1 and R 2 are as defined in the specification. The invention also relates to a...
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6166074 |
Pharmaceutical compositions
Pharmaceutical compositions which are useful for the treatment of cancer or illnesses which arise due to an abnormally elevated cell proliferation comprise acyl derivatives of aromatic aldehydes,...
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6153757 |
Metalloproteinase inhibitors and intermediates useful for their preparation
The invention relates to compounds of formula (1) ##STR1## wherein: Z is O or S; V is a divalent radical which together with C* and N forms a ring having six ring atoms, where each of said ring...
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6124476 |
Catalyst ligands, catalyst compositions, catalyst metal complexes and processes for cross-coupling aromatic boron compounds with aromatic halogens or perfluoroalkylsulfonates
The present invention discloses new organic compounds (e.g., ligands), their metal complexes and compositions using those compounds. The invention also relates to the field of catalysis. In...
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6063928 |
5-lipoxygenase inhibitors
Novel compounds having the ability to inhibit 5-lipoxygenase enzyme and having the following formula I: ##STR1## and the pharmaceutically acceptable salts thereof, wherein Ar 1 is a heterocyclic...
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6020339 |
Aryl furan derivatives as PDE IV inhibitors
The invention encompasses the novel compound of Formula I useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the...
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