Patents in Class 549/437

Matches 1 - 50 out of 185

1 2 3 4 >

Match	Document	Document Title
1	8034820	Pharmaceutical composition The present invention provides pharmaceutical compositions, which are useful for treatment of depression and the like, and which comprises a compound having an adenosine A2A receptor antagonistic...
2	7820838	Method for total synthesis of ecteinascidins and intermediate compounds thereof An intermediate compound for total synthesis of ecteinascidins comprising, a compound represented by general formula 2 having thioether group at C4 site, and the substituent R2 of N12 site is...
3	7816545	Process 054 The present invention is directed to a process for the preparation of a diastereomerically pure dibenzoyl-L-tartrate salt of a compound of formula (III) and to products of said process.
4	7524976	Process for preparing difluorobenzo-1,3-dioxole-5-carboxylic acid derivatives The invention relates to a process for preparing difluorobenzo-1,3-dioxole-5-carboxylic acid and derivatives thereof, and to the use thereof for preparing medicaments and crop protection agents.
5	7498357	Chalcone compounds The present invention provides a novel chalcone compound, its derivative or a salt thereof, each having a suppressive action of NO production or an inhibitory action of aldose reductase. In...
6	7381828	Triazolo pyrimidine compounds The present invention relates to a pyrimidine compound (I) useful as a pharmaceutical intermediate, to a process for preparing said pyrimidine compound, to intermediates used in said process, and...
7	7339078	Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors Selected bis-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to...
8	7259267	Difluorobenzo-1,3-dioxoles The invention relates to difluorobenzo-1,3-dioxoles, to a process for their preparation, and to their use for preparing medicaments and crop protection agents.
9	7208169	Biphenyl carboxamides The invention relates to novel biphenylcarboxamides of the formula (I) in which R1, R2, m, n, R3, Y and A are as defined in the disclosure, to a plurality of processes for preparing these...
10	7202261	Calcilytic compounds The present invention features calcilytic compounds. “Calcilytic compounds” refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inh...
11	7122684	Process for preparing 1,2-diamino compounds The invention provides a multi-step process for preparing 1,2-diamino compounds of formula wherein R1, R1′, R2, R2′, R3 and R4 have the meaning given in the specification and pharmaceutically acc...
12	7019024	Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof.
13	6699911	Catalytic reduction of alkyne compounds A process is provided for the preparation of cyclohexene derivatives of general formula I or II: in which the substituents R1 and R2 independently of one another are defined as follows:R1 is R2 is...
14	6596863	Medical composition containing nitroetheneamine Derivative or salt there of as active constituent Process for producing a nitroetheneamine derivative or its stereoisomer, its tautomer or a salt thereof comprising reacting a compound of the formula with a compound of the formula R6—CH2NO2 to o...
15	6590111	Selective reduction of alkyne compounds A process is provided for the preparation of cyclohexene derivatives of general formula I or II: in which the substituents R1 and R2 independently of one another are defined as follows: R2 is OH or...
16	6518438	Preparation of cyclohexene carboxylate derivatives The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions...
17	6402791	Cationic di-methylenedioxy-benzenes, their use for oxidation dyeing of keratin fibres The subject of the invention is novel dimethylenedioxybenzenes comprising at least one cationic group Z, Z being chosen from quaternized aliphatic chains, aliphatic chains comprising at least one...
18	6384247	Method of producing sesamol formic acid ester and sesamol Heliotropin is oxidized with a percarboxylic acid in the presence of formic acid and an optionally added organic solvent, to thereby produce sesamol at high efficiency while suppressing...
19	6326369	Bicyclic quinone compounds, their production and use A compound of the formula: ##STR1##wherein R1 and R2 each represents a lower alkyl, or R1 and R2 may be bonded together to form a ring; X represents a spacer of which the number of atoms...
20	6288071	1-ethylene-2-alkylene-1,4-cyclohexadiene pesticides Pesticidally active cyclohexadienyl derivative compounds of the formula I that are esters, oximes or amides are claimed. These compounds may be used as fungicides, acaricides and insecticides in...
21	6281240	Diarylsulfonylureas for use in treating secretory diarrhea This invention provides methods of treating secretory diarrhea or cystic fibrosis in a mammal which comprises administering to a mammal in need thereof an effective amount of diarylsulfonylurea....
22	6143907	3-phenyl-1-methylenedioxyphenyl-indane-2-carboxylic acid derivatives Invented is an improved process for preparing aromatic ring-fused cyclopentane derivatives. Preferred compounds prepared by this invention are indane carboxylates and cyclopentanopyridine...
23	6143788	Bis-amino acid hydroxyethlamino sulfonamide retroviral protease inhibitors Selected bis-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to...
24	6060575	1,4-bis(3,4-dicarboxyphenoxy)-2-tert-butylbenzene dianhydride and method of using the same The present invention provides a series of easily processable poly(ether-imide)s that are organic-soluble and can afford colorless films, their organic solutions and their manufacturing process....
25	5998636	Carbamate herbicides Substituted N-phenyl- and N-heteroarylalkylcarbamates of the formula I ##STR1## in which Q is a group ##STR2## R is halogen, trifluoromethyl, cyano, nitro or C1 -C3 haloalkoxy; Z is hydrogen or...
26	5977289	Colorless organic-soluble aromatic poly(ether-imide)s, the organic solutions and preparation thereof The present invention provides a series of easily processable poly(ether-imide)s that are organic-soluble and can afford colorless films, their organic solutions and their manufacturing process....
27	5962737	2-amino-1-phenylpropanols, stereospecific synthesis thereof, and method of optically resolving the same Stereospecific synthesis of the racemic threo isomers of 2-nitro-1-phenylpropanols by reacting a benzaldehyde derivative with nitroalkane in the presence of a tertiary amine and reducing...
28	5936103	Process for the preparation of aromatic compounds containing a heterocyclic system Process for the preparation of aromatic compounds containing a heterocyclic system, having general formula (II): ##STR1## which comprises reacting catechol, optionally substituted, with a methylene...
29	5936128	5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents The present invention relates to novel 5,6-dihydropyrone derivatives and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The 5,6-dihydropyrone...
30	5925673	Benzofurans and benzopyrans as cytoprotective agents Methods for treating inflammnatory pathologies are disclosed. Particularly, the methods utilize pharmaceutical compositions containing certain compounds having an anti-inflanumatory and...
31	5773463	Indane and tetrahydronaphthalene derivatives as calcium channel antagonists This invention describes the use of aminoindane and amino-tetrahydronaphthalene derivatives of general formula (I) ##STR1## in which Ar, X, R1, R2 and n are defined in claim 1, for the manufacture...
32	5739166	Substituted terphenyl compounds for the treatment of inflammation A class of terphenyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II: ##STR1## wherein each of...
33	5721362	Process for producing ecteinascidin compounds The present invention is directed to a synthetic process for the formation of ecteinascidin compounds and related structures, such as the saframycins. In one particularly preferred embodiment, the...
34	5686633	Inks, particularly for ink jet printing Inks, particularly inks for ink jet printing, contain at least one compound of the formula I ##STR1## as a stabilizer. The symbols R1, R2, R3, R4, R3 ' and R4 ' are as defined in claim 1. The...
35	5674811	Cyanoketone derivative and herbicide containing it as an active component A cyanoketone derivatives of the following formula (1) ##STR1## which are characterized by excellent herbicidal activity and effectiveness against a variety of broad leafed weeds, including...
36	5569669	Alkylaminoindane compounds The invention relates to a compound selected from those of formula (I): ##STR1## in which R1, R2, R2', R2", R2'", R3 and n are as defined in the description, an optical isomer, and an addition salt...
37	5569786	Isolation, structural elucidation and synthesis of novel antineoplastic substances denominated "combretastatins" New antineoplastic substances have been isolated, structurally elucidated and synthesized having a general structural formula of: ##STR1## wherein: R1 is OH or OCH3 ; R2 is H or OCH3 ; or R1 R2 is...
38	5567827	4-Hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives The subject of the invention is 4-hydroxyphenylthio derivatives of general formula: ##STR1## in which: R1 and R2, which are identical or different, each represent hydrogen, a methyl or ethyl...
39	5488167	Synthesis of sphingosines Provided by the present invention is a process for the biocatalytic synthesis of optically pure sphingosines from achiral starting material. The stereoisomers of sphingosine are prepared from...
40	5482971	Beta3 -adrenergic agents and their use in pharmaceutical compositions This invention is concerned with novel compounds of formula I: ##STR1## which are selective beta3 -adrenergic agents.
41	5468884	Liquid detergent compositions The invention describes novel highly concentrated, aqueous liquid detergent compositions comprising a) 0.01 to 2% by weight of dibenzofuranyl biphenyls of formula (1) ##STR1## wherein R1, R2, R3,...
42	5440051	Process for the α-chlorination of aryl ethers Aryl ethers are chlorinated in the α-position by a process in which they are metered into a reaction vessel at the same time as chlorine, the reaction being carried out at temperatures in the ...
43	5420273	Condensed heterocyclic compounds The invention relates to compounds of the formula ##STR1## wherein R1 is hydrogen, acyl, lower-alkyl or --CHO, --CH2 OR10, --COR7 or OR13 ; R2, R3 and R4 are, independently, hydrogen, lower-alkyl,...
44	5420309	Fluorinated 1,3-benzo- and 1,3-pyrido-dioxoles, their preparation and their use Novel fluorinated 1,3-benzo- and 1,3-pyrido-dioxoles of formula (I): ##STR1## in which A is C-R4 or N, X is hydrogen, fluorine, chlorine or bromine and R1 to R4 can be identical to or different...
45	5378727	Substituted bicyclic heterocyclic compounds useful as platelet aggregation inhibitors Novel substituted heterocyclic derivatives are provided which inhibit platelet aggregation. This invention also pertains to pharmaceutical compositions and methods of using such derivatives.
46	5250735	2-(N-substituted-aminoalkyl)-5-(E)-alkylidene cyclopentanones, 2-(N-substituted-aminoalkyl)-5-(E)-arylalkylidene cyclopentanones, and derivatives thereof Novel 2-(N-substituted-aminoalkyl)-5-(E)-alkylidene cyclopentanones, 2-(N-substituted-aminoalkyl)-5-(E)-arylalkylidene cyclopentanones, and derivatives thereof having the formula ##STR1## wherein x...
47	5200516	Synthesis of sugars from substituted and unsubstituted arene diols There are disclosed processes for the synthesis of substituted and unsubstituted arene diols useful in the further synthesis of sugars, sugar derivatives, chiral synthons or amino acids.
48	5192765	Certain amines which are muscarinic receptor antagonists Amines of the following formula: ##STR1## where the variables are defined in the specification are useful in the treatment of diseases associated with altered motility and/or tone of smooth muscle.
49	5106867	Method of increasing lean meat in edible animals The present invention discloses substituted 1,3-benzodioxoles which possess anti-diabetic and/or anti-hyperglycemic and/or anti-obesity properties in humans and other animals.
50	5053404	Novel steroid derivatives, pharmaceutical compositions containing them and process for preparing same The invention relates to antiinflammatory compounds of the formula (I), ##STR1## wherein A stands for hydrogen or hydroxyl group; X stands for hydrogen or halogen with the proviso that if A is...

Matches 1 - 50 out of 185

1 2 3 4 >