Patents in Class 549/429

Matches 1 - 50 out of 236

1 2 3 4 5 >

Match	Document	Document Title
1	7595327	Beta-sulfonamide hydroxamic acid inhibitors of tace/matrix metalloproteinase This invention provides compounds of Formula I, having the structure: that are useful in treating diseases or disorders mediated by TNF-α, such as arthritis (rheumatoid arthritis (RA),...
2	7569602	Furan derivatives as EP₄receptor antagonists A compound of formula (I): or a salt, solvate and chemically protected form thereof, wherein one of R 2 and R 5 is: (i) H or an optionally substituted C 1-4 alkyl group; or (ii) an...
3	7534894	Biphenyloxy-acids The present invention relates generally to substituted biphenyloxy acids (such as 4′-aryl-amido-biphenyl-4(3)-yloxy-acids and 4′-aryl-amidomethyl-biphenyl-4(3)-yloxy-acids) and methods of using...
4	7511073	Amines that inhibit a mammalian anandamide transporter, and methods of use thereof One aspect of the present invention relates to amines. A second aspect of the present invention relates to the use of the amines as inhibitors of a mammalian anandamide transporter. The compounds...
5	7507817	Prostaglandin prodrugs Novel compounds, and therapeutic methods, compositions and medicament related thereto are disclosed herein.
6	7468446	Substituted heterocyclic compounds and uses thereof The present invention relates to substituted heterocyclic compounds and compositions comprising a substituted heterocyclic compound. The present invention also relates to methods for preventing or...
7	7468437	Phenyl pyrrolidine ether tachykinin receptor antagonists The present invention is directed to certain phenyl pyrrolidine ether compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular...
8	7442810	Method for the production of defined mixtures of THF, BDO and GBL by gas phase hydrogenation A process for variably preparing mixtures of optionally alkyl-substituted BDO, GBL and THF by two-stage hydrogenation in the gas phase of C 4 dicarboxylic acids and/or derivatives thereof, which...
9	7432284	Estrogen receptor modulators The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen...
10	7423061	Substitute thiophenes and uses thereof This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical salts, compositions and methods of use. These novel compounds provide a treatment or...
11	7419943	Methanoazuenofurans and methanoazulenone compounds and uses of these compounds as fragrance materials The use of novel methanoazulenofuran and methanoazulenone compounds for use as fragrance chemicals, suitable for use incorporated in a wide variety of products such as perfumes, colognes and...
12	7417068	EP₄receptor antagonists A compound of formula (I): or a salt, solvate and chemically protected form thereof, wherein one of R 2 and R 5 is: (i) H or an optionally substituted C 1-4 alkyl group; or (ii)an...
13	7371777	Cyclic compound and PPAR agonist The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester...
14	7351734	Aminoindane derivatives as serotonin and norepinephrine uptake inhibitors The present invention relates to aminoindane derivatives having the formula I wherein X, Y, U, R 1-2 , R 13-16 and R are as defined in the claims, or an acid addition salt thereof. The compounds...
15	7351311	Method for purifying tetrahydrofuran by distillation Crude water-containing tetrahydrofuran is purified by passing the crude tetrahydrofuran through three distillation columns, withdrawing water from the bottom of the first column, recycling...
16	7345181	Process for preparing prostaglandin derivatives and starting materials for the same The present invention provides a process for preparing benzoprostacycline derivatives of formula (1), i.e. 5,6,7-trinor-4,8-inter-m-phenylene PGI2 derivatives, and vinyl tin compounds of formula...
17	7329634	3-Phenyl substituted 3-substituted-4ketolactams and ketolactones The invention relates to novel 3-phenyl-substituted, 3-substituted 4-ketolactams and -lactones of the formula (I) in which Q, W, X, Y, A, B and G are as defined in the disclosure, to...
18	7316851	Electroluminescent material, electroluminescent element and color conversion filter An electroluminescent element is disclosed, comprising an electroluminescent material and a fluorescent substance emitting light having an emission maximum at the wavelength different from that of...
19	7276573	Method for producing monoesters and diesters of polytetrahydrofuran and of tetrahydrofuran copolymers The present invention provides a process for preparing mono- or diesters of polytetrahydrofuran or of tetrahydrofuran copolymers by polymerizing tetrahydrofuran in the presence of at least one...
20	RE39794	Process for the simultaneous production of maleic anhydride and its hydrogenated derivatives A process is described for the co-production of maleic anhydride and at least one C 4 compound selected from butane-1,4-diol, γ-butyrolactone, and tetrahydrofuran in which maleic anhydride is...
21	7256203	Dicationic 2,5-diarylfuran aza-analogs as anti-protozoan agents A compound of Formula (I): wherein: X is selected from the group consisting of O, S, and NR 17 , where R 17 is hydrogen or lower alkyl; A and Y are CH, N, NR 17 , O, or S; C 1 and C 2 ...
22	7148318	Method for producing polytetrahydrofurane having a low color indices The invention provides a process for preparing polytetrahydrofuran, tetrahydrofuran copolymers, their monoesters or diesters and the monoesters or diesters of polytetrahydrofuran having a low color...
23	7144909	Phenoxy substituted benzocondensed heteroaryl derivatives as thyroid receptor ligands This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders,...
24	7122561	Treatment of skin conditions The present invention provides piperine and analogues or derivatives thereof for the treatment of skin conditions treatable by stimulation of melanocyte proliferation, such as vitiligo, and also...
25	7109343	Metal catalysts and methods for making and using same Compounds having the formula: are disclosed. M 1 and M 2 are the same or different and are transition metal atoms or ions; Z 2 and Z 3 , independently, are the atoms necessary to complete a...
26	7105707	Process for preparing alkynyl-substituted aromatic and heterocyclic compounds Mono- and disubstituted aryl or heterocyclic acetylenes are produced by a process comprising reacting an aryl nitrile with an alkynylzinc compound, a bis-alkynylzinc compound, or an...
27	7091344	Infrared chromophores An infrared dye, characterized in that the dye comprises of Formulae 1 to 5
28	7081467	C2-disubstituted indan-1-ones and their derivatives, processes for their preparation and their use as pharmaceuticals The present invention is directed C2-disubstituted indan-1-ones of the Formula I, physiologically acceptable salts, and physiologically functional derivatives thereof, and pharmaceutical...
29	7074944	Method for producing polytetrahydrofuran In a process for the single-stage preparation of polytetrahydrofuran and/or tetrahydrofuran copolymers having a mean molecular weight of from 650 to 5000 dalton by polymerization of tetrahydrofuran...
30	7064222	Processes for the preparation of 2-methylfuran and 2-methyltetrahydrofuran Processes are disclosed for the preparation of 2-methylfuran and 2-methyltetrahydrofuran. The continuous vapor-phase processes are commercially viable and efficient because they permit the...
31	7057055	Process for preparing a deuterated or tritiated compound A process for labeling organic compounds with deuterium and tritium is described using specific catalysts.
32	7049329	Amines that inhibit a mammalian anandamide transporter, and methods of use thereof One aspect of the present invention relates to amines. A second aspect of the present invention relates to the use of the amines as inhibitors of a mammalian anandamide transporter. The compounds...
33	6930188	Stable hydrate of a muscarinic receptor antagonist A stable solid hydrate of a muscarinic receptor antagonist is useful in the treatment of irritable bowel syndrome, diverticular disease, oesophageal achalasia, chronic obstructive airways disease,...
34	6921831	Modified BiMo catalyst and process for use thereof Modified lead/bismuth/molybdate catalysts containing vanadium, copper, or gold have been prepared, and are selective to the corresponding furan compound from the gas phase oxidation of an...
35	6906196	Processes for the preparation of 1,5-diaryl-3-substituted-pyrazoles Provided are processes and chemical intermediates useful for preparing a compound of the formula I wherein X is selected from the group consisting of C 1 -C 6 trihalomethyl; C 1 -C 6 ...
36	6903132	Non-peptide GnRH agents, pharmaceutical compositions and methods for their use Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, prodrugs, and active...
37	6894039	Selenophene anti-tumor agents Novel selenophene compounds useful as anti-tumor agents are described. Preferred compounds include compounds of formula I: wherein R 1 and R 2 are independently selected from the group...
38	6875784	Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives The present invention provides certain [3.1.0] bicyclic oxazolidinone derivatives of Formulea I and II, described herein, or pharmaceutically acceptable salts or prodrugs thereof that are...
39	6864225	Cyclic ketals, fragrance compositions containing the same and methods of using the same Compounds of the general formula (I) are described: wherein each of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 independently represents a substituent selected from the group consisting of hydrogen,...
40	6844375	4-methylene-1,3-dioxolanes as cross-linking agents The invention relates to: 4-methylene-1,3-dioxolanes of the general formula (I) wherein R1 denotes hydrogen, C 5 -C 6 -cycloalkyl or C 1 -C 4 -alkyl; m and n, which may be the same or...
41	6812354	Process for preparing 3-methyltetrahydrofuran Disclosed is a process for the preparation of 3-methyltetrahydrofuran (MeTHF) from 3-(hydroxymethyl)tetrahydrofuran (HOMeTHF) or 3-formyltetrahydrofuran (FTHF) by contacting HOMeTHF or...
42	6764829	Nucleoside hydrolase and nucleoside phosphorylase detection kits, dipsticks and substrates The invention relates to a method of detecting and/or assaying nucleoside hydrolases or nucleoside phosphorylases using a chromogenic substrate. Preferred chromogenic substrates have formula (I)...
43	6762304	Metal catalysts and methods for making and using same Compounds having the formula: are disclosed. M 1 and M 2 are the same or different and are transition metal atoms or ions; Z 2 and Z 3 , independently, are the atoms necessary to complete a...
44	6762198	Dihetero-substituted metalloprotease inhibitors Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the compounds have...
45	6730800	Method for the production of tetrahydrofuran Unsubstituted or alkyl-substituted THF is obtained by catalytic hydrogenation in the gas phase of C 4 -dicarboxylic acids and/or their derivatives using a catalyst comprising <80% by weight,...
46	6716987	Derivatives of benzofuran or benzodioxazole compounds An oxygen-containing heterocyclic compound represented by following Formula (I): wherein R 1 and R 2 independently represent hydrogen, lower alkyl, cyano, —(CH 2 ) n —E 1 —CO—G 1 ...
47	6683211	Phenyl-propargylether derivatives The invention relates to phenyl-propargylether derivatives of the general formula I including the optical isomers thereof and mixtures of such isomers, wherein R 1 is hydrogen, alkyl,...
48	6683107	Furans, benzofurans, and thiophenes useful in the treatment of insulin resistance and hyperglycemia This invention provides compounds of Formula I having the structure wherein R 1 and R 2 are each, independently, hydrogen, alkyl of 1-6 carbon atoms, halogen, perfluoroalkyl of 1-6 carbon...
49	6680391	Treatment of skin conditions The present invention provides piperine and analogues or derivatives thereof for the treatment of skin conditions treatable by stimulation of melanocyte proliferation, such as vitiligo, and also...
50	6660728	Thienyl substituted acylguanidines as inhibitors of bone resorption and vitronectin receptor antagonists The present invention relates to thienyl substituted acylguanidine derivatives, such as compounds of formula (I) in which R 1 , R 2 , R 4 , R 6 , A, B and D have the meanings indicated in the...

Matches 1 - 50 out of 236

1 2 3 4 5 >