Patents in Class 549/407

Matches 1 - 50 out of 203

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Match	Document	Document Title
1	7615650	Process for producing chroman compound The invention provides a process for producing a chroman compound represented by formula (1), characterized in that the process includes allowing a phenol, an unsaturated compound, and a...
2	7560575	Process for preparation of racemic Nebivolol A process of making racemic [2S[R[R[R]]]] and [2R[S[S[S]]]]-(±)α,α′-[iminobis(methylene)]bis[6-fl uoro-3,4-dihydro-2H-1-benzopyran-2-methanol] of the compound of the formula (I) ...
3	7528267	Method for enantioselective hydrogenation of chromenes A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the...
4	7429411	Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition The compound (1) according to the invention has general solid-state properties necessary for a compound, stability against heat, light and the like, a suitable optical anisotropy, a suitable...
5	7427693	Polar liquid crystal Compounds that are useful in compositions for flat panel displays, for example, are provided. The compounds provided are polar, and are useful in low threshold voltage mixtures. The compounds...
6	7410998	Inhibitors of NADH:ubiquinone oxidoreductase Benzopyran-based inhibitors of NADH:ubiquinone oxidoreductase for inhibiting the growth of cancer cells.
7	7384976	Nebivolol and its metabolites in combination with nitric oxide donors, compositions and methods of use The invention describes novel compositions comprising nebivolol and/or at least one metabolite of nebivolol and at least one nitric oxide donor, and, optionally, at least one antioxidant or a...
8	7365095	Chromane and chromene derivatives and uses thereof Compounds of formula I or pharmaceutically acceptable salts thereof are provided: wherein each of R 1 , R 2 , R 3 , R 4 , y, m, n, and Ar are as defined, and described in classes and subclasses...
9	7312232	Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof The present invention provides an antiproliferative compound having the structural formula wherein X is oxygen, nitrogen or sulfur; Y is selected from the group consisting of oxygen, nitrogen...
10	7297715	PPAR alpha selective compounds for the treatment of dyslipidemia and other lipid disorders A class of chromane and chromene compounds having the structure shown below and pharmaceutically acceptable salts thereof are useful as therapeutic compounds, particularly in the treatment and...
11	7217706	Propanolamine derivatives This invention relates to new propanolamine derivatives or salts thereof represented by the following formula [I]: Wherein each symbol is as defined in the specification or salts thereof which...
12	7148240	Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same The invention relates to benzofuran or benzothiophene derivatives of general formula: These compounds are of use as medicinal products, in particular in the treatment of pathological syndromes...
13	7144919	Polyoxyethylene-polyoxypropylene vitamin E and process for preparation thereof The present invention relates to polyoxyethylene-polyoxypropylene (POE-POP) vitamin E, which is prepared from vitamin E by polyethoxylation and polypropoxylation, and a method for preparing the...
14	7138430	Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use The invention describes novel nitrosated and/or nitrosylated nebivolol, novel nitrosated and/or nitrosylated metabolites of nebivolol and novel compositions comprising at least one nitrosated...
15	7045514	Therapeutic heterocyclic compounds Provided herein is a compound having the formula (I): Wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety,...
16	6890952	Cyclic substituted aminomethyl compounds and medicaments comprising these compounds Cyclic substituted aminomethyl compounds of general formula IA and IB, methods for production thereof, intermediates in said production methods, a medicament containing at least one of said cyclic...
17	6855833	Methods for producing amino substituted chromanes and intermediates thereof Disclosed are processes for producing chromane compounds, preferably chroman-2-yl acetic acid compounds and 6-amino-chroman-2-yl acetic acid esters which are intermediates for producing platelet...
18	6835845	Methine compound, material for organic luminescence element, and organic luminescence element using the same A is a novel methine compound, for example, which is represented by the following formula (I): wherein R 1 , R 2 , R 3 , R 4 and R 5 each represents a hydrogen atom or a substituent; X...
19	6818666	Bi-aromatic compounds linked via a heteroethylene radical, and pharmaceutical and cosmetic compositions using them Bi-aromatic compounds linked via a heteroethynylene radical are provided along with pharmaceutical and cosmetic compositions containing these compounds and methods for their use.
20	6750247	Sponge-derived terpenoids and methods of use Compounds that are effective lipoxygenase inhibitors, and methods and pharmaceutical compositions for inhibiting lipoxygenases and for treatment of lipoxygenase-mediated conditions in humans and...
21	6716873	Tocopherol ester compounds Disclosed are novel tocopherol ester compounds having the formula wherein X is a chain of 2 or 3 carbon atoms, e.g., ethylene and trimethylene, joining the 2 carbonyl groups to which they are...
22	6700001	Process for stereoselective synthesis of 2-hydroxymethyl chromans A process for the stereoselective synthesis of 2-hydroxymethyl-chromans of formula (II) is provided where R, R 1 , R 2 and R 3 are as defined herein. The compound of formula (II) is prepared...
23	6699860	Di-substituted aminomethyl-chroman derivative beta-3 adrenoreceptor agonists This invention is related to novel di-substituted aminomethyl chroman derivatives which are useful in the treatment of beta-3 receptor-mediated conditions.
24	6660871	Synthesis of 4H-chromene derivatives Substituted 4H-chromene derivatives are a new class of compounds that bind to Bcl-2 protein and induce apoptosis in tumor cells. The present invention is directed to an efficient synthetic method...
25	6653488	Process for producing benzopyran carboxamide A first process for producing a benzopyran carboxamide represented by the general formula [1] includes reacting 3-aminopropionitrile.½ sulfate, N≡CCH 2 CH 2 NH 2 .½(H 2 SO 4 ), with a...
26	6653472	Preparing amidines derived from 6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid New intermediates of the formula (II)B described below for the synthesis of amidine derivatives of (−)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, such as for example...
27	6646136	Chroman derivatives Chroman derivatives of the formula I in which R 1 is acyl having 1-6 C atoms, —CO—R 5 or an amino protective group, R 2 is H or alkyl having 1-6 C atoms, R 3 , R 4 in each case...
28	6638972	Chroman and benzofuran derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.
29	6638970	Substituted alkylene diamine compounds Novel compounds of the general formula: and pharmaceutically acceptable acid addition salts thereof, wherein the compounds are useful in therapy to protect skeletal muscles against damage...
30	6635650	Substituted dimeric compounds The invention relates to compounds of formula (I): A-G 1 -Cy-G 2 -Cy-G 3 -B (I) wherein: A represents NR 1 C(Q)R 2 , C(Q)NR 2 R 3 or NR 1 C(Q)NR 2 R 3 , B represents NR 1 C(Q)R 2 , C(Q)NR 2 R 3...
31	6620947	Compounds for use in 11-oxa prostaglandin synthesis Novel processes and intermediates useful in the preparation of 11-oxa prostaglandin analogs are disclosed.
32	6599933	Tocotrienol derivative, process for producing the same and &ggr -CEHC delivering agent The object of the present invention is to provide a tocotrienol derivative which is highly water-soluble and shows high bioavailability in the living body and γ-CEHC delivering agent. (A...
33	6518264	Azetidine derivatives, their preparation and medicaments containing them Disclosed are azetidine derivatives of formula: their optical isomers, their salts, their preparation and medicaments containing them.
34	6482950	Squarylium compounds, and processes and intermediates for the synthesis of these compounds Squarylium compounds of the formula: wherein Q 1 and Q 2 are each independently a pyrylium, thiopyrylium, selenopyrylium, benzpyrylium, benzthiopyrylium or benzselenopyrylium nucleus, and R 1 ...
35	6479670	Selective retinoid acid receptor agonists This invention relates to new selective retinoid acid receptor agonists of formula I wherein the symbols are as defined in the specification to their pharmaceutically acceptable salts,...
36	6479540	Compositions of tocol-soluble therapeutics Tocol-based compositions of charged amphiphilic and water soluble pharmaceutically active compounds or their charged precursors are prepared by forming a tocol-soluble ion pair with an oppositely...
37	6429320	Processes for the purification of tocopherol and/or sterol compounds and compositions containing orthoborate ester mixtures Processes for purifying compounds are disclosed which include reacting (i) a mixture of at least one tocopherol compound or sterol compound, and an alcohol having from about 10 to 30 carbons with...
38	6403638	2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors Compounds having the formulas below, where R is H, lower alkyl, or a pharmaceutically acceptable salt, and where R 1 represents i-propyl, t-butyl or n-butyl groups, have selective RXR retionoid...
39	6369099	Method of locking 1 α-OH of vitamin D compounds in axial orientation A method of modifying or altering the structure of a 1α-hydroxylated vitamin D compound to increase its biological activity by altering the conformational equilibrium of the A-ring to favor a...
40	6358995	Carboxylic acid derivatives having fused rings The present invention provides a medicament exhibiting excellent retinoic acid receptor agonism. A Carboxylic acid derivative having a fused ring which is represented by the following formula or a...
41	6350453	Tocotrienols and geranylgeraniol from Bixa orellana byproducts A source of material known as a byproduct solution of Bixa orellana seed components, which is obtained as an oily material after the bulk of annatto color, is removed from either the aqueous...
42	6348605	Process for preparing 3-hydroxymethyl chromen-4-ones 3-(Hydroxymethyl)chromen-4-ones of formula (I) are described and a process for preparing said compounds. The process consists in reacting the compounds of general formula (II) wherein R is...
43	6313160	Substituted heterocyclic compounds, method for preparing and compositions containing same The invention relates to compounds of formula (I): ##STR1## wherein: R 1 , R 2 and R 3 are as defined in the description, X is as defined in the description, Y represents an oxygen atom,...
44	6310074	Substituted dimeric compounds The invention relates to compound of formula (I): A--G 1 --Cy--G 2 --Cy'--G 3 --B (I) wherein: A represents a grouping NR 1 C(Q)R 2 , C(Q)NR 2 R 3 or NR 1 C(Q)NR 2 R 3 , B...
45	6297273	Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions Disclosed and claimed are cocoa extracts, compounds, combinations thereof and compositions containing the same, such as polyphenols or procyanidins, methods for preparing such extracts, compounds...
46	6288071	1-ethylene-2-alkylene-1,4-cyclohexadiene pesticides Pesticidally active cyclohexadienyl derivative compounds of the formula I that are esters, oximes or amides are claimed. These compounds may be used as fungicides, acaricides and insecticides in...
47	6281240	Diarylsulfonylureas for use in treating secretory diarrhea This invention provides methods of treating secretory diarrhea or cystic fibrosis in a mammal which comprises administering to a mammal in need thereof an effective amount of diarylsulfonylurea....
48	6136986	Process for preparing substituted chroman derivatives The invention relates to a process for preparing substituted chroman derivatives of the general formula VII, ##STR1## where X is the group --CN, --COOR 3 , --CHO, --CH 2 OR 7 or --CH(OR 8 ) 2 , ...
49	6136985	CLA esters and uses thereof The present invention provides CLA esters and uses thereof. More particularly, the present invention provides a composition for topical use comprising CLA esters and a topical carrier. In addition,...
50	6124347	Chromene derivatives and salts thereof, and pharmaceuticals containing the same Disclosed are chromene derivatives represented by the following formula: ##STR1## wherein R 1 s represent alkyl, alkoxy or like groups, R 2 represents a hydrogen atom or an alkyl group, R 3 ...

Matches 1 - 50 out of 203

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