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7465814 |
Sulfonate compound and fluorescent probe using the same
The present invention provides a sulfonate compound, including a structure represented by a general formula (I) below,
where, in the formula (I), an atomic group A-O is an atomic group...
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7326447 |
Benzochromene derivatives
The present invention relates to benzochromene derivatives of the formula I
in which the various parameters are as defined in the text, and to liquid-crystal media which comprise these...
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7285672 |
Process for isolating of α-mangostin
The invention relates to a process for obtaining and purifying pure α-mangostin from the rind of the fruit (mangosteen) of Garcinia mangostana.
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7019024 |
Pharmaceutical for treatment of neurological and neuropsychiatric disorders
The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula:
or a pharmaceutically acceptable salt thereof.
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6740756 |
Fluorescent lanthanide chelates
The present invention provides complexing agents of Formula I which contain novel photosensitizers and produce long-lived fluorescence for use in bioaffinity assays, especially HTRF (homogeneous...
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6458974 |
Synthesis of β-lapachone and its intermediates
A novel process for synthesizing β-lapachone (beta-lapachone), an agent that has demonstrated significant antineoplastic activity against human cancer lines. The process comprises the conversion...
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6384045 |
Tricyclic and tetracyclic pyrones
This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone...
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6204396 |
Method for producing calcium fulvate from humus material
A method produces calcium fulvate from naturally-occurring humus material, such as leonardite, or humic shales. The humus material containing solid fulvic acid and solid humic acid is mixed with...
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6147229 |
Method for producing magnesium fulvate from humus material
A method produces magnesium fulvate from naturally-occurring humus material, such as leonardite, or humic shales. The humus material containing solid fulvic acid and solid humic acid is mixed with...
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5977077 |
Xanthone analogs for the treatment of infectious diseases
Therapeutic compositions for the treatment of infectious diseases are disclosed. These compositions comprise xanthones and xanthone derivatives, such as 2,3,4,5,6-pentahydroxyxanthone. Also...
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5763625 |
Synthesis and use of β-lapachone analogs
3-Substituted-β-lapachone analogs and their use either alone or to augment chemotherapy or radiotherapy to induce programmed neoplastic cell death without exhibiting toxicity to surrounding normal...
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5726208 |
Heterocyclic tertiary amines
New compounds of formula: ##STR1## wherein: --A--D--E, X, n, Y and Z are as defined in the description, in racemic form and in the form of optical isomers, and their addition salts with...
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5672621 |
Carbonarin antiinsectan metabolites
Carbonarins A, B, C, D, E, F, G, and H have been isolated from the sclerotia of the fungus Aspergillus carbonarius. The carbonarius are effective for controlling Coleopteran and Lepidopteran...
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5633357 |
Synthesis of carboxylic acid glucuronides
A method of producing a carboxylic acid glucuronide by reacting a carboxylic acid precursor with a blocked sugar epoxide precursor is disclosed. Also disclosed are: deuterated 11-nor-Δ 8 - or Δ...
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5623080 |
Fluorone and pyronin Y derivatives
A compound of the formula (I) or (II): ##STR1## where R 1 , R 2 , R 5 and R 6 are the same or different and represent a hydrogen atom or a halogen atom and R 1 and R 2 may combine to form a...
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5597943 |
Phospholipase A.sub.2 inhibitor
The present invention relates to the new thielocin derivatives, which exhibit phospholipase A 2 inhibitory activity of the formula: ##STR1## wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R...
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5011952 |
Phospholipase A2 inhibitor
A compound of the formula: ##STR1## wherein the wave line means α-bond or β-bond, which compound is useful as a phospholipase A 2 inhibitor. Process for the production of the compound,...
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4927849 |
Sulfonamido derivatives inhibiting the aldose reductase enzyme system and pharmaceutical compositions containing them
The xanthosulfonamido and benzensulfonamido derivatives corresponding to the formula: ##STR1## wherein x represents hydrogen, alkyl, alkoxy or halogen, Y represents an alkyl, alkoxy or halogen and...
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4628087 |
Process for the preparation of pharmacologically active compounds containing a sulfoxide group
Process for the preparation of pharmacologically active compounds containing a sulfoxide group by oxidation of a thioether with hypochlorite in an alkaline medium at a pH higher than 10 and at a...
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4585876 |
Novel xanthones and thioxanthones
Novel xanthones and thioxanthones of the formula I ##STR1## in which A, X, Y, Z, E and E' are as defined in patent claim 1, are described. A is preferably --S-- and E and E' are preferably bonded...
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4556651 |
Secalonic acid derivatives as antitumor agents
A secalonic acid derivative of the formula (I); ##STR1## wherein R is ##STR2## wherein R 1 and R 2 each independently is a hydrogen atom or a C 1 -4 alkyl group; R 3 is a hydrogen atom, a C 1 -4...
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4496447 |
Aromatic-aliphatic ketones useful as photoinitiators
Compounds of the formula ##STR1## wherein A, X, Z, R 1 , R 2 , R 3 , R 4 , n and m are defined hereinbelow are effective photoinitiators especially for the photopolymerization of ethylenically...
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4424373 |
Secalonic acids
Secalonic acids having a 2,4'-linkage of the formula (I) or a 4,4'-linkage of the formula (II). ##STR1## .
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4290954 |
Tetrahydroxanthone derivatives
A tetrahydroxanthone derivative represented by the general formula: ##STR1## wherein R is a hydrogen atom, a hydroxyl, cyano, lower alkyl, lower alkoxy, lower acyloxy, benzoyloxy or tetrazolyl...
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4250097 |
Compositions for and a method of preventing diabetic complications
Compositions containing and methods of employing as the essential ingredients substituted xanthone carboxylic acid compounds which are useful in the prevention of complications of diabetes. Methods...
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4242267 |
Process for preparing 5-alkyl-7-(S-alkyl-sulfonimidoyl)-xanthone-2-carboxylic acids
A novel process for the preparation of xanthane-2-carboxylic acids of the formula ##STR1## wherein R is selected from the group consisting of hydrogen and alkyl of 1 to 9 carbon atoms and R 1 is...
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4221800 |
Cycloalkenochromone
Certain substituted cycloalkenochromones and pharmacologically acceptable salts thereof are disclosed as being useful in the treatment of allergies. The compounds have the structure: ##STR1## X is...
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4217361 |
Disubstituted xanthone-2-carboxylic acid antiallergy agents
Compositions containing and methods employing, as the essential ingredient, novel substituted xanthone-2-carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods...
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4127573 |
Ditetrazole substituted acridone compounds
Acridone and xanthone compounds substituted by at least one tetrazolyl group in one ring, and further substituted in the other ring, optionally for the acridones have antiallergic activity.
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4078078 |
Novel xanthone-2-carboxylic acid compounds
Novel xanthone-2-carboxylic acid compounds of the formula ##STR1## wherein A is selected from the group consisting of --COOR', a 1H-tetrazol-5-yl and a 1H-tetrazolylcarbamoyl, R' is selected from...
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4061768 |
Certain cyclic carbonyl compounds used in the prophylaxis of allergic conditions
A pharmaceutical composition and method for inhibiting the symptoms of allergic conditions such as asthma or allergic rhinitis which comprises administering a compound of the formula ##STR1## where...
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4007205 |
7-Substituted-9-oxoxanthene-2-carboxaldehydes
There are disclosed 7-substituted-9-oxoxanthene-2-carboxaldehydes of the formula: ##STR1## in which R is lower alkoxy or hydroxy. These compounds are indicated in the management of allergic...
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3989721 |
Disubstituted xanthone carboxylic acid compounds
Compositions containing and methods employing, as the essential ingredient, novel disubstituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods...
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3985783 |
Process for ring acylation of phenols
Mono- and poly-phenols and derivatives thereof are ring acylated by a Friedel-Crafts acylation reaction in which the hydroxy groups are protected by prior silylation.
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3950342 |
Acridone-dicarboxylic acids
Certain acridone and xanthone compounds, each of which is 2-substituted by a carboxyl group or a salt, ester or optionally substituted amide thereof and each of which is optionally substituted in...
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3925415 |
Method for manufacture of novel compounds
Di-(2'-tetrahydrofuranyl)-secalonic acid D or di-(2'-tetrahydropyranyl)-secalonic acid D is active as an anti-tumor agent for mice. It is produced by reaction of secalonic acid with...
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3910957 |
Xanthone carboxylic acids and derivatives
Compositions containing and methods employing, as the essential ingredient, xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods for preparing these...
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3901934 |
Substituted salicylonitriles
A process for the preparation of a cyanophenol of formula (I) ##SPC1## wherein Z is a substituent in the 4- or 6- position with respect to the hydroxy group, characterized in that cyanide ions are...
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3890328 |
N,N-dioxides of bis-basic cyclic ketones
Novel N,N-dioxide derivatives of bis-basic cyclic ketones, their preparation and use for the prevention and inhibition of virus infections.
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3859286 |
BIS-BASIC KETONES OF XANTHENE AND XANTHEN-9-ONE
Novel bis-basic ketones of xanthene and xanthen-9-one have antiviral activity when administered orally and parenterally. The compounds are represented by the following formula: ##SPC1## Wherein Z...
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3859307 |
BIS-BASIC ESTERS AND AMIDES OF XANTHENE AND XANTHONE
Novel bis-basic esters and amides of xanthene and xanthone of the formula ##SPC1## Wherein: Z is oxygen or H 2 ; each of R 1 and R 2 is hydrogen, (lower)alkyl of 1 to 6 carbon atoms, cycloalkyl...
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3835158 |
HETEROCYCLIC SUBSTITUTED XANTHONE CARBOXYLIC ACID COMPOUNDS
Compounds containing and methods employing, as the essential ingredient, heterocyclic substituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions....
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3818040 |
ALKENYL AND ALKYNYL SUBSTITUTED XANTHONE CARBOXYLIC ACID COMPOUNDS
Compositions containing and methods employing, as the essential ingredient(s), novel alkenyl and alkynyl substituted xanthone carboxylic acid compounds which are useful in the treatment of allergic...
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3484445 |
DERIVATIVES OF CHROMONE-2-CARBOXYLIC ACID
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3454582 |
XANTHENE-9-OL-9-CARBOXYLIC ACID ESTERS
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3652765 |
Title is not available
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3706768 |
Title is not available
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3821251 |
Title is not available
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3801598 |
Title is not available
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3646030 |
Title is not available
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