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7584630 Photochromic ocular devices  
Described are photochromic ocular devices such as contact lenses and intraocular lenses made of an organic polymeric material and at least one photochromic material capable upon exposure to actinic...
7329687 Flavanoid compounds as chemotherapeutic, chemopreventive, and antiangiogenic agents  
Compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the...
7253207 Quinones as disease therapies  
Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided.
7250120 Benzo-, naphtho- and phenanthrochromene substituted by carbamated or ureated phenyls, preparation thereof and compositions and articles containing them  
Disclosed are novel benzo-, naphtho- and phenanthrochromenes substituted by carbamated or ureated phenyls having the following general formula (I): wherein R 1 represents a group their...
7105685 Cannabinol derivatives  
The invention provides cannabinol derivatives and pharmaceutical preparations thereof.
6967249 Photochromic 3H-naphtho[2,1-b]-pyran compounds and photochromic articles produced therewith  
Specific photochromic 3H-naphtho[2,1-b]-pyran compounds useful with various types of synthetic resin materials to form photochromic articles, especially ophthalmic lenses, and photochromic articles...
6939007 Photochromic bis-naphthopyran compounds and methods for their manufacture  
The invention provides photochromic bis-naphthopyran compounds as well as methods for their manufacture and their use. The bis-naphthopyran compounds of the invention exhibit a wide range of color,...
6890950 Lapachone delivery systems, compositions and uses related thereto  
In part, the present invention is directed to a system comprising a lapachone or a prodrug thereof and a polymer, such as a biocompatible and optionally biodegradable polymer, methods for treatment...
6887533 Fluorinated oxaanthracenes and their use in liquid-crystal mixtures  
Compounds of the formula (I) where: X 1 is H or F G 1 -G 2 is —CH 2 —CH— or CH═C— R 1 , R 2 are a) H b) the M 2 -A 2 -R 5 moiety c) for example, a straight-chain or...
6863843 Naphthopyran compounds, photoresponsive compositions and lenses  
A photochromic [1,2-b] naphthopyran having a fluoro substituent in at least one of the 7-position or the 9-position of the naphthopyran provides a stable photochromic compound with a narrow range...
6700001 Process for stereoselective synthesis of 2-hydroxymethyl chromans  
A process for the stereoselective synthesis of 2-hydroxymethyl-chromans of formula (II) is provided where R, R 1 , R 2 and R 3 are as defined herein. The compound of formula (II) is prepared...
6630597 Photochromic 6-aryl substituted 3H-naphtho(2,1-b)pyrans  
Described are novel photochromic 6-aryl substituted 3H-naphtho[2,1-b]pyran compounds, examples of which are naphthopyran compounds having a substituted aryl group at the number 6 carbon atom and...
6627121 Photochromic naphthopyran compounds  
A photochromic naphthopyran of formula (I) wherein R 1 through R 15 , which may be the same or different, are independently selected from the group consisting of hydrogen, C 1 -C 4 alkyl, C 1 -C...
6602903 Substituted heterocyclic compounds  
The invention relates to compounds of formula (I): and medicinal products containing the same are useful in treating or in preventing melatoninergic disorders.
6555028 Polymeric matrix compatibilized naphthopyrans  
Described are polymeric matrix compatibilized naphthopyran compounds, examples of which are certain 2H-naphtho[1,2-b]pyrans, 3H-naphtho[2,1-b]pyrans and indeno[2,1-f]naphtho[1,2-b]pyrans each...
6478989 Aromatic substituted naphthopyrans  
Described are photochromic 2H-naphtho[1,2-b]pyrans characterized by having an aromatic substituent in the 5 position. The aromatic group at 5-position of the naphthopyran is a substituted or...
6478988 Photochromic substituted naphthopyran compounds  
The present invention relates to naphthopyrans, particularly 3,3-[substituted]-naphtho[2,1-b]pyrans and 2,2-[substituted]-naphtho[1,2-b]pyrans and particularly to novel substitution on the...
6458974 Synthesis of β-lapachone and its intermediates  
A novel process for synthesizing β-lapachone (beta-lapachone), an agent that has demonstrated significant antineoplastic activity against human cancer lines. The process comprises the conversion...
6403347 HIV integrase inhibitors  
Natural products such as certain chaetochromins are described. These compounds are useful in the inhibition of HIV integrase, the prevention or treatment of infection by HIV and the treatment of...
6399791 Naphthopyran derivatives, compositions and (co) polymer matrices containing same  
For subject, the present invention has novel naphthopyran derivatives of formula: optionally substituted in position(s) 2, 3, 4, 6, 7, 8, 9 or/and 10; the substituent Z in position 5 being of...
6398987 Naphthopyrans having a perfluoroalkyl substituent in position 5, preparation and compositions and matrices containing them  
The present invention relates to novel compounds of the naphthopyran type which have a perfluoroalkyl group (X) in position 5. These compounds are of formula (I) given below: These compounds (I)...
6353102 Photochromic naphthopyrans  
Described are novel photochromic naphtho[1,2-b]pyran compounds having certain substituents at the 2 position of the pyran ring, certain substituents at the 5 and 6 positions and optionally at the...
6348604 Photochromic naphthopyrans  
Described are novel photochromic 2H-naphtho[1,2-b]pyran compounds essentially characterized by having two adjacent moderate to strong electron donor substituents at the 8 and 9 positions or a fused...
6340766 Substituted napthopyrans  
Described are novel reversible photochromic naphthopyran compounds, examples of which are compounds having a cycloalkyl ester substituent at the number 5 carbon atom and optionally certain...
6337409 Photochromic naphthopyran compounds  
A naphthopyran compound represented by the formula: wherein R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , and R 11 are each selected from the group consisting essentially of hydrogen, a first...
6281366 Photochromic [3H]naphtho[2,1-b]pyran compounds containing an acetylenic substituent, process for their manufacture, and photochromic materials and articles obtained  
The present invention relates to photochromic [3H]naphtho[2,1-b]pyran compounds containing an acetylenic substituent, process for their manufacture, and photochromic materials and articles obtained...
6248264 Neutral coloring photochromic 2H-naphtho[1,2-b] pyrans and heterocyclic pyrans  
Compositions comprising a naphtho [1,2-b]pyran of formula (I): ##STR1## wherein R 7 and/or R 9 is hydrogen or an amino group provided that R 7 and R 9 are not both hydrogen, and the other...
6211374 Water soluble, pyran-based photochromic compounds having carboxylate functionality  
The present invention provides water-soluble, pyran-based photochromic compounds characterized by improved stability when in an open, excited configuration. The advantages of the present invention...
6197225 Chromene compound  
A photochromic compound featuring a large fading rate to prevent a change in the color tone at the time of fading, exhibiting little color after aged, and exhibiting good durability in the...
6190580 Diaryl-2H-naphthopyrans  
Photochromic diaryl-2H-naphthopyran structures, which dye photochromically well at room temperature, lighten up quickly when incorporated into ophthalmic lenses, possess longevity, and due to their...
6146554 Photochromic naphtopyrane colorants, method for the production and use thereof, photochromic object  
What is described here are photochromic naphthopyrane dyes with different substituents whose properties can be set by controlled selection of the substituents. In this manner it is possible to take...
6113814 Polymerizable polyalkoxylated naphthopyrans  
Described are novel photochromic polymerizable polyalkoxylated naphthopyran compounds, examples of which are certain 2H-naphtho[1,2-b]pyrans, 3H-naphtho[2,1-b]pyrans and...
6096246 Photochromic naphthopyrans, compositions and articles containing them  
The invention relates to photochromic compounds of general formula (I), in which: R3 and R5 are C1-C6 alkoxy groups and the rest of the R groups represent various substituents. ##STR1##
6080338 Water soluble photochromic compounds, compositions and optical elements comprising the compounds  
Described are novel water soluble photochromic naphthopyran and benzopyran compounds having an alkylaminoalkylamino group on the pyran portion or on the pyran portion and the naphtho- or...
6043269 cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes  
The present invention relates to therapeutically active compounds of formula I ##STR1## a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel...
5990305 Photochromic diaryl-3H-naphthopyrane  
Disclosed is a photochromic compound having a diaryl-3H-napthopyran structure, which has at the 8-position a nitrogen atom-linked hetercyclus, in which the heterocylcus can also have a HALS...
5969163 Ortho-quinone derivatives, novel synthesis therefor, and their use in the inhibition of neoplastic cell growth  
A process for the preparation of β-lapachone and dunnione derivatives of formulae I and II ##STR1## wherein, the a solution of lawsone in dimethylsufoxide at a temperature of -78° C. or less is...
5961892 Polyalkoxylated naphthopyrans  
Described are novel photochromic polyalkoxylated naphthopyran compounds, examples of which are certain 2H-naphtho 1,2-b!pyrans, 3H-naphtho 2,1-b!pyrans and indeno 2,1-f!naphtho 1,2-b!pyrans, each...
5952515 Diaryl-2h-napthopyrans  
The description concerns a photochromicsubstance, with a diaryl-2H-naphthopyrane having a link in the form Y--Ar, Z--Ar, Y--Ar--Y, Y--Ar--Y', Y--Ar--Z, Z--Ar--Z or Z--Ar--Z', in which Y, Y', Z and...
5912362 Process for preparing isochroman compounds  
High-purity isochroman compounds can be obtained in high yields according to a simple and economical process for preparing isochroman compounds, comprising the step of adding an aquesous solution...
5843989 C.sub.4 -amide substituted compounds and their use as therapeutic agents  
The invention provides certain 5 and/or 8 substituted benzopyran, pyranopyridine or tetrahydroquinaline compounds having C 4 -amide substituent and processes for making them. The compounds...
5808100 Chromene compounds and photochromic materials  
A photochromic compound which is initially colored less, exhibits excellent durability and features high color density and high color fading rate, and a photochromic material thereof. The...
5783598 Antiretroviral naphthoquinone compounds compositions and uses thereof  
The present invention provides novel antiviral naphthoquinone compounds, which may be isolated from plants of the genus Conospermum or synthesized chemically, in accordance with the present...
5744070 Photochromic substituted naphthopyran compounds  
Described are novel reversible photochromic naphthopyran compounds, examples of which are 3H-naphtho 2,1-b!pyrans having an acyl or aroyl oxy-bearing substituent at the number 6 carbon atom and...
5707557 Photochromic 3H-naphthopyrans  
Photochromic compounds with a 3H-naphthopyran structure having at least one pyrene moiety in the 3-position, a method for preparing such compounds, and the use of such compounds for producing...
5705102 Photochromic spironaphthopyran compounds  
A naphthopyran compound represented by the formula: ##STR1## wherein R 1 , R 2 , R 5 , R 6 , R 7 , R 8 , R 9 , and R 10 are each selected from the group consisting essentially of hydrogen, a...
5686586 Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same  
A polycyclic aromatic compound having the formula ##STR1## and its salts have useful therapeutic and cosmetic action particularly in psoriasis. In the formula, X represents --CHCH--, O or S, ...
5663375 Pharmaceutical compounds  
Pharmaceutical compounds of the formula ##STR1## in which n is 0, 1 or 2 and R 1 is attached at any of the positions 7, 8, 9 or 10, and each R 1 is halo, carboxy, trifluoromethyl, hydroxy, C 1 -4...
5658501 Substituted naphthopyrans  
Described are novel reversible photochromic 2H-naphtho[1,2-b] pyran compounds, examples of which are compounds having certain substituents at the number 5 carbon atom of the naphtho-portion of the...
5656206 Substituted naphthopyrans  
Described are novel reversible photochromic 2H-naphtho[1,2-b]pyran compounds, examples of which are compounds having certain substituents at the number 5 carbon atom of the naphtho portion of the...
Matches 1 - 50 out of 185 1 2 3 4 >