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9024044 Heteroarylcarboxylic acid ester derivative  
Compounds represented by the following formula (I), are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
8691867 Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction  
The present invention is a method for the treatment of alcohol abuse and/or addiction comprising administering to a subject in need thereof a therapeutically effective amount of one or more novel...
8269025 Purification of p-dioxanone  
The present disclosure provides methods for purifying p-dioxanone. In embodiments, crude p-dioxanone may be contacted with at least one isocyanate-functionalized scavenger. The at least one...
8222435 Dioxolane and dioxane derivatives and a process for their preparation  
The present invention relates to novel acylmethylene-1,3-dioxolanes and acylmethylene-1,4-dioxanes of the general formula (I) in which R1, R2, R3 and n have the meanings given in the description,...
7442793 Peptide deformylase inhibitors  
Novel PDF inhibitors and novel methods for their use are provided.
7196108 Bicyclic heterocycles for the treatment of diabetes and other diseases  
The invention relates to certain bicyclic heterocycles havng the structure shown below which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2...
7129355 Process for preparing kifunensine intermediate and kifunensine therefrom  
A novel method for the preparation of a compound of formula (I) from an N—protected-D-mannosamine. A compound of formula (I) is a useful intermediate for the preparation of kiftnensine, a potent...
6864254 Inhibitor for 20-hete-yielding enzyme  
An inhibitor for 20-hydroxyeicosatetraenoic acid production which comprises as the active ingredient a specific hydroxyformamidine derivative or a pharmacologically acceptable salt thereof. It is...
6559144 Bicyclic amino acids  
Compounds of the formula I in whichX, Y, Z, R1, R2, R3, R4, R5, R7, R8, R11, m and n have the meanings stated in claim 1, and their physiologically acceptable salts can be used as integrin...
6329027 Chlorobenzene derivatives, liquid-crystal composition, and liquid-crystal display elements  
Provided are liquid crystalline compounds having excellent physical properties and being excellent in miscibility with other liquid crystal materials; liquid crystal compositions comprising the...
6063939 Process for preparing unsaturated cyclic ethers  
Unsaturated cyclic ethers of the formula I ##STR1## where Z is --(CHR4)q -- or --(CHR4)q --O--, q is 0, 1, 2 or 3 and R1,R2,R3,R4 are hydrogen or C1 -C4 -alkylare prepared by reacting diols of the...
6040339 Urea derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prophylactic use  
Compounds of formula (I): ##STR1## wherein: R1 is alkyl; R2a, R2b, R2c and R2d are the same or different and each is hydrogen, optionally substituted alkyl or various other organic groups; R3 is...
6037482 Process for catalytic addition of nucleophiles to alkynes or allenes  
PCT No. PCT/EP96/05457 Sec. 371 Date Jun. 15, 1998 Sec. 102(e) Date Jun. 15, 1998 PCT Filed Dec. 6, 1996 PCT Pub. No. WO97/21648 PCT Pub. Date Jun. 19, 1997A process for the catalytic addition of...
6022895 Substituted amino compounds and their use as substances having an analgesic effect  
Substituted amino compounds of general formula (I) ##STR1## are described, as are a method of preparing them and their use as drugs, especially as analgesics.
5880147 Amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prohylactic use  
Compounds of formula (I): ##STR1## wherein: R1 is alkyl; R2a, R2b, R2c and R2d are the same or different and each is hydrogen, optionally substituted alkyl, --(CO)--B1 (wherein B1 is hydrogen or...
5718845 Tricyanovinyl substitution process for NLO polymers  
Nonlinear optical compounds which contain a heteroaromatic ring and may further comprise a tricyanovinyl group attached to the heteroaromatic ring.
5709820 Alkenyl cyclohexane derivatives and liquid crystal compositions  
Liquid crystalline alkenyl cyclohexane compounds of formula (I) having a nematic phase over a broad temperature range, a higher elastic constant ratio K33 /K11 and a lower viscosity, liquid...
5698715 Preparation of unsaturated cyclic ethers  
A process for the preparation of unsaturated cyclic ethers of the general formula I ##STR1## in which Z denotes --(CHR4)q or --(CHR4)q --O-- q is 0, 1, 2 or 3 and R1, R2, R3, and R4 denote...
5688972 Preparation of acetals  
A process for the preparation of acetals by reacting one or more ethylenically unsaturated compounds with carbon monoxide, hydrogen and a liquid or dissolved organic nucleophilic compound...
5565436 Production stimulators of nerve growth factors comprising cyathane derivatives  
A production stimulator of nerve growth factor contains a new cyathane derivative of the form ##STR1## where R is either CHO or CH2 OH.
5562808 Method and apparatus for decontaminating a liquid surfactant of dioxane  
A method and apparatus are disclosed for decontaminating a liquid surfactant of a dioxane having a vapor pressure which is higher than the surfactant. A contaminated liquid surfactant is directed...
5405988 9-substituted bicyclo[3.3.0]octane derivatives, process for their production and their pharmaceutical use  
The invention relates to 9-substituted bicyclo[3.3.0]octane derivatives of formula I, ##STR1## and their salts with physiologically compatible bases, as well as the α-, β- or γ-cyclodextrin...
5391544 Cyathane derivatives and antimicrobial agents containing same  
New cyathane derivatives shown by Formula (1) or (2) given below have the effect of stimulating production of nerve growth factors and antimicrobial effects: ##STR1## where R is either CHO or CH2 OH.
5278301 Route to glycals in the allal and gulal series  
Axial anomeric sulfoxides generated via thiophenol Ferrier rearrangement of glucal and galactal derivatives are used to synthesize glycals of the gulal and allal series. An application of the...
5258406 Sulfonimidamides  
This invention provides certain sulfonimidamide compounds, formulations and method of use of these compounds in treating susceptible neoplasms.
5104985 Labdane process  
Novel labdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
5091521 Cis-platinum complexes, a process for the preparation thereof, and pharmaceuticals containing these compounds  
Compounds of the general formula I ##STR1## in which R1 represents a hydrogen atom or an alkyl group of the formula CH3 (CH2)n --where n=0 to 5, R2 represents a hydrogen atom when X is a carbamoyl...
5081263 Dioxane adducts of aromatic meta- or para-hydroxy-carboxlic acids  
The invention relates to the dioxane adducts of armoatic meta-or para-hydroxycarboxylic acids, which consist, per mole, of 1 mole of 1,4-dioxane and about 2 moles of hydroxycarboxylic acid. The...
5077037 Novel compositions for magnetic resonance imaging  
Methods and compositions for enhancing magnetic resonance imaging in at least a portion of a warm-blooded animal.
5047558 Process for the preparation of a dioxane adduct of 2-hydroxynaphthalene-6-carboxylic acid  
The invention relates to the dioxane adduct of 2-hydroxynaphthalene-6-carboxylic acid which adduct comprises 1 mol of 1,4-dioxane and about 2 mol of 2-hydroxynaphthalene-6-carboxylic acid per mol....
5003089 Preparation of cyclic 6-membered to 8-membered vinylene-1,2-dioxy compounds  
Cyclic 6-membered to 8-membered 1,2-vinylenedioxy compounds of the general formula I ##STR1## where A is ##STR2## R1 to R7 independently of one another are each hydrogen, C1 -C8 -alkyl, C2 -C16...
4988827 Ether isonitriles and radiolabeled complexes thereof  
Ether-substituted isonitriles, Tc99m complexes thereof, and processes for myocardial tissue radioimaging using the Tc99m complexes.
4980503 Conversion of glycol formates to monocarboxylic acids  
It has been surprisingly discovered in accordance with the present invention that glycol formates and their alkyl ether derivatives can be substantially selectively converted to monocarboxylic...
4978430 Method for dehydration and concentration of aqueous solution containing organic compound  
An improved method for dehydration and concentration of an aqueous solution containing an organic compound is disclosed. The solution is evaporated to produce a gaseous mixture comprising an...
4948469 Separation of formic acid from dioxane by extractive distillation with amides  
Dioxane cannot be completely removed from dioxane and formic acid mixtures by distillation because of the presence of the maximum azeotrope. Dioxane can be readily removed from dioxane - formic...
4925959 Dioxane adduct of 2-hydroxynaphthalene-6-carboxylic acid and process for the preparation thereof  
The invention relates to the dioxane adduct of 2-hydroxynaphthalene-6-carboxylic acid which adduct comprises 1 mol of 1,4-dioxane and about 2 mol of 2-hydroxynaphthalene-6-carboxylic acid per mol....
4889939 Fluoropolyethers containing end groups endowed with anchoring capacity  
Compounds suitable for being used as lubricants, having general formula: (I) RO--(C3 F6 O)m --(CFXO)n --CFX--L, or (II) R"CFXO--(C3 F6 O)x (CFXO)y --(C2 F4 O)z --CFX--L, where R=--CF3, --C2 F5,...
4866188 Synthesis of cyclic ethers  
A process is disclosed for preparing a cyclic ether which comprises cyclodehydrating a polyhydroxy compound of the general formula HOR1 HC--R2 --CHR3 OHin which R1 and R3, each of which is the...
4842638 Herbicidal tetrahydro(thio)pyran-2,4-dione derivatives  
Tetrahydro(thio)pyran-2,4-dione derivatives of the formula ##STR1## where R1 is hydrogen, a cation, alkylcarbonyl, C2 -C10 -alkenylcarbonyl, or benzoyl which is unsubstituted or substituted by...
4806658 Cleavage of polyethylene glycol ethers by hydrolysis  
High molecular weight polyethylene glycol monoethers are cleaved to prepare lower oligomeric reaction products by contacting a mixture of the high molecular weight polyethylene glycol monoether...
4801358 Separation of acetic acid from dioxane by extractive distillation  
Dioxane cannot be completely removed from dioxane and acetic acid mixtures by distillation because of the presence of the maximum azeotrope. Dioxane can be readily removed from dioxane - acetic...
4764626 Method for producing 1,4-dioxane  
A 1,4-dioxane is produced by subjecting a one-phase liquid reaction mixture of at least one compound of the general formula: RO--(CH2 CH2 O)n --R (I)where n is an integer from 1 to 6 and each R is...
4760154 Synthesis of dioxane  
A catalyzed conversion of diethylene glycol to 1,4-dioxane, undertaken over zeolites, ZSM-5, ZSM-23, ZSM-48 and zeolite beta, is characterized by high selectivity.
4755323 Liquid-crystalline dielectrics  
New 1,4-dioxanes of the formula I ##STR1## wherein R1 and R2 each signify and alkyl group with 1 - 10 C-atoms, wherein one or two CH2 groups can also be replaced by O-atoms, F, Cl, Br or CN, R2...
4730069 Cis-platinum complexes with a pentaerythritol derivative as the ligand, a process for their preparation and a pharmaceutical agent containing these compounds  
Compounds of the general formulae I and II ##STR1## in which R1 and R2 independently of one another represent H--(CH2)a --(O--(CH2)b)c --O, where a=0 to 4, b=1 to 4 and c=1 to 7, an alkoxy or...
4699986 Imino compounds useful for making β-lactams  
There is presented optically uniform β-lactams of the formulae ##STR1## wherein Z is a readily cleavable acyl group, R1 is amino or a group convertible into amino, R2 is hydrogen or a readily...
4677213 2,5-diamino-1,4-dioxane derivatives and process for production thereof  
Dioxane derivatives are disclosed which are represented by the formula (I): ##STR1## wherein, R stands for a hydrogen atom or an aliphatic residue having 1 to 10 carbon atoms; R1 and R2 stand for...
4435582 Manufacture of macrocyclic polyethers  
This invention deals with a process for the preparation of macrocyclic polyethers of the general formula: ##STR1## wherein x is 1-9; k is 0 or 1 and each R, which may be the same or different,...
4405799 Treatment of effluents containing dioxane  
The invention relates to the treatment to remove dioxane from gaseous effluents by contacting the effluent with a concentrated acid having a pK1 value of not more than 5 to complex the dioxane...
4365071 Production of anhydrous 1,4-dioxane  
This invention relates to the production of anhydrous 1,4-dioxane by the dimerization of ethylene oxide in the presence of an acidic type of cation exchanger, preferably an acidic cation exchanger...

Matches 1 - 50 out of 104 1 2 3 >