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7288664 |
Reverse Kleiner method for manufacturing nitrogen dioxide, nitric oxide, nitric acid, metallic ascorbates and alkyl ascorbates of vitamin C
In this invention new chemical reactions, new chemical processes are established, and these chemical reactions, chemical processes can be used with the designed system to produce nitrogen dioxide,...
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7282597 |
Ascorbic acid derivatives and skin-whitening cosmetics
It is an object to provide an L-ascorbic acid derivative which can keep the L-ascorbic acid stable to heat and light and thus has a long shelf life, which is high in permeability into the skin,...
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7230124 |
Ascorbic acid compounds, methods of synthesis and application use thereof
A composition of L-ascorbic acid derivatives is described comprising L-ascorbic acid and lysine or lysine moieties, wherein L-ascorbic acid is covalently bound to the lysine or lysine moieties. The...
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7102019 |
Cosmetic and pharmaceutical preparations comprising ascorbic acid derivatives
An ascorbic acid derivative of the formula Ia:
where the variables independently of one another have the following meanings:
R 1 and R 2 independently of one another are hydrogen or C...
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7045546 |
Stabilized derivatives of ascorbic acid-3-phosphate
Novel derivatives of ascorbic acid and compositions comprising them are provided. The novel derivatives are of the following general formula (I): where R1 is a C2–C22 saturated or unsaturated...
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7038065 |
Process for catalytically producing organic substances by partial oxidation
A process for catalytically generating organic substances by partial oxidation of an organic feedstock in the presence of molecular oxygen at temperatures in the range from 200 to 500° C. in at...
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6949537 |
PI-3 kinase inhibitor prodrugs
The invention provides novel prodrugs of inhibitors of PI-3 kinase. The novel compounds are LY294002 and analogs thereof comprising a reversibly quaternized amine.
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6864376 |
Process for producing ascorbic acid
The present invention comprises the use of sulfite additives to reduce discoloration of L-ascorbic acid produced from acid or aqueous solutions of 2-keto-L-gulonic acid. In one aspect, the present...
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6864284 |
Ascorbic acid compounds, methods of synthesis and application use thereof
A composition of L-ascorbic acid derivatives is described comprising L-ascorbic acid and lysine or lysine moieties, wherein L-ascorbic acid is covalently bound to the lysine or lysine moieties. The...
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6841536 |
Prodrugs and conjugates of thiol- and selenol-containing compounds and methods of use thereof
Disclosed is a prodrug of the formula:
where A is a sulfur or a selenium, and R is derived from a mono- di- or oligo- saccharide.
Also disclosed is a prodrug of the formula:
where A is...
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6774247 |
Aqueous solution of ascorbic acid and method for producing same
Disclosed is an aqueous solution of ascorbic acid which contains an excess of an emulsifier with an HLB value of about 9 to about 18, for example a polysorbate, a method of manufacture of such...
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6749832 |
Labelled ascorbic acid derivatives
Compounds of formula (I) where: X 1 is OH or SH or NH 2 or —L-Z; X 2 and X 3 are the same or different and each is H, C 1-4 alkyl, benzyl a protecting group or —L-Z, X 4 is H or C 1-4 ...
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6740762 |
Process for ascorbic acids using alkaline earth silicate catalysts
Disclosed is a process for the preparation of ascorbic acids from 2-keto-hexonic acids or 2-keto-hexonic acid derivatives using alkaline earth silicate catalysts. The process may be carried out in...
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6716997 |
Systems and methods for generation of ascorbic acid with reduced color
The present invention describes the synthesis of ascorbic acid with reduced color. The present invention employs palladium catalysts for the synthesis of ascorbic acid from 2-keto-gulonic acid or...
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6685965 |
PROCESS FOR STABILIZING LEVOGYRE ASCORBIC ACID (LAA), A STABLE AQUEOUS LAA COMPOSITION, A PROCESS FOR PREPARING A STABLE TOPICAL SOLUTION, AN EMULSION, A VITAMIN PRODUCT, AND A METHOD FOR COSMETIC, PHARMACEUTICAL OR NUTRITIONAL TREATMENT
The present invention refers to a process for stabilizing LAA in an aqueous medium, which includes the step of contacting the LAA with at least one-compound capable of forming hydrogen bridges with...
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6677373 |
Polymorphic B form of 3-(cyclopropylmethoxy)-4-&lsqb 4-(methylsulfonyl)phenyl&rsqb -5,5-dimethyl-5H-furan-2-one
This invention is related to a polymorphic B Form of 3-(cyclopropylmethoxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dime
thyl-5H-furan-2-one characterized by the following parameters: cristalline system...
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6630330 |
Ascorbic acid production from yeast
Herein is disclosed a method of generating ascorbic acid from yeast. In one embodiment, the yeast is a Zygosaccharomyces spp. or a Kluyveromyces spp. growing in a medium comprising an ascorbic acid...
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6617463 |
Method for the production of L-ascorbic acid by lactonization of 2-keto-L-gulonic acid or s2-keto-L-gulonate esters
The invention relates to a process for the preparation of L-ascorbic acid, in which free 2-keto-L-gulonic acid or C 3 -C 10 -alkyl 2-keto-L-gulonate is lactonized under acidic conditions in the...
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6613919 |
Method for resolving racemic mixtures of 5-substituted 4-hydroxy-2-furanones
This invention affords a solution to the technical problem of obtaining one or both enantiomers of 5-substituted 4-hydroxyfuran-2-ones in pure form by resolution with enantiomerically pure bases....
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6610863 |
Continuous process for producing L-ascorbic acid
The present invention provides methods and an apparatus for the manufacture of an L-ascorbic acid product in high yield by direct conversion of an aqueous solution containing 2-keto-L-gulonic acid...
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6573393 |
Method for producing L-ascorbic acid
The invention relates to a method for producing L-ascorbic acid from 2-keto-L-gulonic acid or 2,3-4,6-diacetone-2-keto-L-gulonic acid. The reaction is carried out in the presence of water and...
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6482851 |
Synthesis of dysidiolide and uses thereof
This invention provides a process for the preparation of a racemic mixture of dysidiolide a method for inhibiting growth of cancerous cells comprising contracting an amount of the racemic mixture...
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6476239 |
Process for the preparation of ascorbic acid
The present invention is a process for the preparation of ascorbic acid using a simulated moving bed (SMB) reactor system to accomplish the simultaneous conversion of KLG or a derivative of KLG to...
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6444144 |
Polyethoxylated ascorbic acid derivatives as a novel antioxidant and process for preparing thereof
Provided with a novel ascorbic acid derivative represented by the formula (I) and a method for preparing the same: wherein R 1 and R 2 are different from each other and, independently H or...
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6416791 |
Alimentary integrator
The invention relates to an alimentary integrator constitued by a compound of potassium bicarbonate (KHCO 3 ) and an anti-oxidant agent that comprises D ribose (C 6 H 10 O 5 ) and that can comprise...
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6388098 |
Process for preparing ascorbic acid-2-monophosphate salt
A process for preparing a high-purity ascorbic acid-2-monophosphate salt in a convenient manner and in a high yield, comprising hydrolyzing an ascorbic acid-2-polyphosphate or a salt thereof in the...
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6362348 |
Additive for inkjet printing, recording solution, method for preventing discoloration and fading of image, and recording sheet
An additive for inkjet printing, comprising a stabilized ascorbic acid derivative. Also disclosed are a recording solution, a method for preventing discoloration and fading of an image, and a...
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6344567 |
Process for producing ascorbic acid-2-phosphoric ester salts
A process for producing an ascorbic acid-2-phosphoric ester salt, where an ascorbic acid-2-phosphoric ester salt solution reduced in the content of excess phosphoric acid or a salt thereof mingled...
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6340746 |
Prodrugs and conjugates of thiol- and selenol- containing compounds and methods of use thereof
Disclosed are prodrugs as follows: (I) a prodrug of the formula where A is a sulfur or a selenium, and R is a mono- di- or oligo-saccharide; (II) a prodrug of the formula where A is sulfur or...
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6320061 |
Solvent exchange process
A process for recovering an organic acid or a metal salt thereof includes contacting an alcoholic phase containing one or more organic acid(s) or metal salt(s) thereof with water under conditions...
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6294678 |
Treatment for cancer and compounds for use therewith
A treatment for cancer and compounds for use therewith are provided. The compounds treat cancer by correcting a TATA box lesion in DNA that leads to the cancer's uncontrolled cell proliferation....
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6274744 |
Preparation of alkali metal salts of L-ascorbic acid
A process for preparing alkali metal salts of L-ascorbic acid comprising the following steps: a) esterifying 2-keto-L-gulonic acid or diacetone-2-keto-L-gulonic acid with a C 1 -C 10 -alkohol...
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6265436 |
Substituted 5-biphenyl-3,4-dihydroxy-2(5H)-furanones and method of use therefor
The present invention broadly relates to racemic or optically active 5-substituted 3,4-dihydroxy-2(5H)-furanone compounds and their pharmaceutically acceptable salts, useful for treating a...
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6255291 |
Composition and method for treating cancer and immunological disorders resulting in chronic conditions
A composition containing alph-alanine, adenosine compound and a glucan. Methods for treating cancer and immunological disorders with said composition.
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6248905 |
Acyl derivatives of glycosyl-L-ascorbic acid
Acyl derivatives of glycosyl-L-ascorbic acids which have a higher oil-solubility than L-ascorbic acid, glycosyl-L-ascorbic acids, and inorganic esters of L-ascorbic acid such as phosphates and...
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6197977 |
Process for the preparation of L-ascorbic acid
The invention relates to a process for the preparation of L-ascorbic acid, which comprises lactonizing a melt of alkyl 2-keto-L-gulonate under acidic conditions.
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6177598 |
Preparation of sugar alcohols
A process for the hydrogenation of a sugar or a mixture of two or more thereof comprises the following step: Bringing the sugar or the mixture of two or more thereof into contact with hydrogen...
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6177470 |
Methods of treatment using ascorbyl gamma linolenic acid or ascorbyl dihomo-gamma-linolenic acid
Optimum conditions for prostaglandin synthesis are provided by internally administering an ascorbic-6-acid ester of gamma-linolenic acid or an ascorbic-6-acid ester of dihomo-gamma-linolenic acid.
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6172242 |
Process for the production of erythorbic acid
The invention provides a process for the recovery of erythorbic acid from an aqueous feed solution containing values of erythorbic acid at a concentration of less than 0.7 mol/kg, comprising...
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6169187 |
Process for recovery of ascorbic acid
The invention provides a process for the recovery of ascorbic acid from a feed containing at least one precursor of ascorbic acid comprising converting the precursor into at least one product, the...
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6150543 |
Enzymatic preparation of regioselective fatty acid esters of ascorbic acid
The invention relates to a process for the enzymatic preparation of regioselective fatty acid esters of ascorbic acid and selected fatty acid alkyl esters. Ascorbic acid and fatty acid alkyl esters...
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6143906 |
Ascorbyl sorbates
Ascorbyl sorbates of the formula I, ##STR1## where the variables independently of one another have the following meanings: R 1 and R 2 are hydrogen, C 1 -C 12 -alkyl, C 1 -C 20 -acyl; ...
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6136832 |
5,5-disubstituted-3,4-dihydroxy-2(5H)-furanones and methods of use therefor
The present invention relates to synthetic methods for the production of both optically active and racemic 5,5-disubstituted-3,4-dihydroxy-2(5H)-furanones;...
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6084110 |
Stable vitamin C preparation
This invention relates to a stable vitamin C preparation and a method for stabilizing vitamin C preparation. According to the invention, the vitamin C preparation stable for a long period of time...
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6060046 |
Antifouling compositions
An antifouling composition that comprises an effective amount of a furanone of the structure shown and a suitable carrier therefor. In the figure, substituents R 1 , R 2 and R 3 are each a...
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6037481 |
Process for stabilizing levogyre ascorbic acid (LAA), a stable aqueous LAA composition, a process for preparing a stable topical solution, an emulsion, a vitamin product, and a method for cosmetic, pharmaceutical or nutritional treatment
The present invention refers to a process for stabilizing LAA in an aqueous medium, which includes the step of contacting the LAA with at least one compound capable of forming hydrogen bridges with...
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6037480 |
Process and compositions for the recovery of ascorbic acid
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6020367 |
Supersaturated ascorbic acid solutions
A method of preparing a supersaturated and stable solution of ascorbic acid, supersaturated ascorbic acid solutions and compositions containing such supersaturated solutions. A polyol vehicle is...
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6005000 |
5,5-Disubstituted-3, 4-dihydroxy-2(5H)-furanones and methods of use therefor
The present invention relates to synthetic methods for the production of both optically active and racemic 5,5-disubstituted-3,4-dihydroxy-2(5H)-furanones;...
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5998634 |
One-step synthesis of vitamin-C (L-ascorbic acid)
A method is provided for producing L-ascorbic acid (Vitamin-C) in a single process step. Starting material, particularly a mixture of compounds from the group consisting of glucose, sorbitol,...
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