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5426195 |
Process for the catalytic dehydrogenation of diols
Diols of 3 to 10 carbon atoms are catalytically dehydrogenated over a catalyst containing copper and chromium in a first stage in which the diols are passed in the liquid phase over the catalyst,...
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5416224 |
Process for converting α-acyl-substituted lactones to α-alkylidene-substituted lactones
A convenient stereoselective process for the preparation of α-alkylidene-substituted-γ-butyrolactones and δ-valerolactones is provided. The process involves reacting an α-acyl lactone, an...
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5405974 |
Process for producing a lactone or an ester
A process for producing a lactone or an ester represented by the following general formula (2), wherein R 1 and R 2 , identical or different, each represents (C 1 --C 20 ) alkyl group; alkyl...
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5401857 |
Process for making γ-butyrolactones
A cyclocarbonylation process for making γ-butyrolactones under mild temperature and pressure conditions is disclosed. In the process, an allylic alcohol reacts with carbon monoxide in the presence...
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5376676 |
Process of using anti-inflammatory furanones as selective calcium channel inhibitors
4-(C 10 -C 20 )alkyl-2(5H)-furanone compounds are selective calcium channel inhibitors and useful for treatment of diseases such as hypertension, angina, cardiac arrythmia, pulmonary hypertension,...
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5374744 |
Method for manufacturing 4-substituted-Y-lactone and novel substance
An alkynyl group having a triple bond at the carbon atom at the 1-position is introduced to a carbon atom at the 1-position of 2,3-O-isopropylidene-D-ribofuranose. The diol part is then cleaved to...
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5371106 |
3,4-diaryl-5(H)-furan-2-one based compounds with fungicidal activity
Compounds based on 3,4-diaryl-(5H)-furan-2-one, with fungicidal activity, having the general formula (I): ##STR1##
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5358964 |
Benzylidene-lactone and their thiocarbonyl analogs as inhibitors of proteoglycan degradation
The manufacture and use of compounds of the formula ##STR1## wherein Y is O or S, R 1 is hydrogen or alkyl, and R 2 , R 3 , R 4 and R 5 are hydrogen or various substituent groups, and...
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5336686 |
17 Methylene lactones of steroids
A compound selected from the group consisting of a compound of the formula ##STR1## wherein the substituents are defined as in the application having antiglucocorticoid and antiprogestomimetic...
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5322942 |
Synthesis of optically active lactones from L-aspartic acid and intermediates thereof
Optically active lactones are described, such as an intermediate lactone having the formula ##STR1## where R and R 2 are each independently alkyl with 1 to 6 carbon atoms, cycloalkyl with 6 to 10...
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5319108 |
Method for producing (R,Z)-5-tetradecen-4-olide
A method for producing (R,Z)-5-tetradecen-4-olide, comprising the following reaction formulas; ##STR1##
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5310944 |
Process for producing carboxylated compound
A process for producing a carboxylated compound, which comprises reacting a carbonyl compound with hydrogen peroxide in the presence of an organo-arsenic acid of the formula (1), ##STR1## wherein:...
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5288811 |
Cyclic carbonyl containing compounds via radical grafting
Accordingly, novel carbonyl containing compositions are prepared by contacting, in the presence of a free radical initiator, a compound selected from the group consisting of saturated hydrocarbons,...
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5278321 |
Process for simultaneously producing lactone and aromatic carboxylic acid
A process for simultaneously producing a lactone and an aromatic carboxylic acid, which comprises oxidizing a cyclic ketone and an aromatic aldehyde wherein: the cyclic ketone/aromatic aldehyde...
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5274128 |
Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereof
Described is a process for the preparation of compositions of matter containing octalactones defined according to the structure: ##STR1## which includes the stereoisomers having the structures:...
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5231192 |
Process for the preparation of alpha-alkyl lactones
Process for the preparation of α-alkyl lactones by the steps of first reacting an α-acyl lactone, an aldehyde, and an alkali metal hydroxide together to form an α-alkylidene lactone, and then...
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5216177 |
Method of preparing trans-3,4-disubstituted-γ-lactones
First, levoglucosenone is made to react with methyl lithium in the presence of copper iodide in order to introduce a methyl group into an enone group of levoglucosenone, and to obtain...
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5210229 |
Process for the preparation of gamma-butyrolactone
Gamma-butyrolactone is prepared by catalytic dehydrogenation of 1,4-butanediol in a gaseous phase in the presence of a catalyst comprising copper, chromium, and manganese and/or barium. Improvement...
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5189182 |
Preparation of 5-methylbutyrolactone
5-Methylbutyrolactone is prepared by a process in which a pentenoic ester of the formula I X--CO 2 R (I), where X is CH 2 CH--CH 2 --CH 2 --,...
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5183908 |
Process for the preparation of substituted furanones
This invention relates to an improved process for the preparation of 3-acyl-5-alkyldihydro-2(3H)-furanones according to the following reaction scheme: ##STR1## wherein R and R 1 are hydrogen or...
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5179077 |
4-methyl-3-pentyl-2(5H)-furanone
The invention concerns the novel compound, 4-methyl-3-pentyl-2 (5H)-furanone, I, a process for the manufacture of I and fragrance and flavor compositions containing I. ##STR1##
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5175310 |
Process for producing alkylthio- and arylthio-substituted carboxylic acids and their thioesters
A process is provided for producing alkylthio-substituted carboxylic acids and arylthio-substituted carboxylic acids and their corresponding alkylthio-substituted thioesters and...
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5164499 |
Nitroaryl carbonyl compounds, nitrodihydroaryl carbonyl intermediates thereto, and processes
Nitroaryl carbonyl Formula (IIA) compounds, their nitrodihydroaryl carbonyl Formula (I) intermediates, processes for preparing Formula (II) compounds, and a process for preparing Formula (I)...
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5136055 |
Method for production of dicarboxylic acid and lactone
A 21-carbon aliphatic branched chain dicarboxylic acid and a 21-carbon lactone are produced by reacting fatty acid (which contains linoleic acid) with acrylic acid via iodine catalysis, and...
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5130157 |
Process for concentrating lactones
The present invention relates to a process for obtaining an aroma concentrate that is enriched in lactones. The present invention is particularly concerned with a process for concentrating lactones...
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5128370 |
Furans and lactones from sterptomycetes and the use thereof
New furans and lactones from streptomycetes, a process for the preparation thereof, and the use thereof. It is possible with the aid of various streptomycetes species to prepared new compounds...
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5114493 |
Smoking compositions containing a hexahydrobenzofuranone flavorant
This invention provides smoking compositions which contains a 6-substituted hexahydrobenzofuranone flavorant additive. Under cigarette smoking conditions the flavorant additive enhances the aroma...
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5110954 |
Dehydrogenation of diols
A process is provided for the production of lactones by the catalytic dehydrogenation of aliphatic diols containing from 3-7 carbon atoms and optionally one or more ether linkages in the diol...
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5106995 |
Production of lactones from diols
A method for converting 1,4 and 1,5 aliphatic saturated diols to lactones is disclosed wherein the diol is reacted with a chemical oxidizing agent and a ruthenium containing catalyst at...
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5059611 |
Anti-inflammatory 5-hydroxy-2-furanones
New 5-hydroxy-2-furanone compounds have anti-inflammatory, immunosuppressive and anti-proliferative activity and are useful in treating psoriasis and modifying calcium homeostasis.
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5045564 |
Anti-inflammatory 2-furanones
New 2-furanone compounds have calcium channel antagonist activity and are useful as anti-inflammatory agents and in treating psoriasis.
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5030328 |
Method of separating γ-butyrolactone from mixtures containing diethyl succinate
A method of separating γ-butyrolactone from a mixture containing ethanol, tetrahydrofuran, water, n-butanol, 1,4-butanediol, diethyl succinate and γ-butyrolactone, by distillation in vacuum columns.
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4988825 |
Oxidation of aldehydes and ketones using alkali metal perborates
Aldehydes and ketones, other than acetone, are oxidized with an alkali metal perborate in the presence of an acid.
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4968817 |
Manufacture of gamma-crotonolactone by carbonylation of glycidol
A process for preparing a substituted or unsubstituted gamma-crotonolactone is provided which comprises reacting a substituted or unsubstituted glycidol of the formula: ##STR1## wherein R 1 , R 2 ,...
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4960906 |
Process for the preparation of lactones from higher alkenols
Process for the preparation of lactones, having 4 or 5 carbon atoms in the ring by reacting a higher alkenol with a carbon monoxide containing gas in the presence of a catalytic system comprising ...
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4954623 |
Recovery of difluoro sugar
A process for recycling the difluoro sugar in the synthesis of 2,2-difluoronucleosides proceeds by removing the base moiety of α-difluoronucleosides by reduction and hydrolysis, followed by...
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4945173 |
Process for the production of gamma-butyrolactone
A process is described for the production of substantially pure gamma-butyrolactone from a feed mixture containing a major amount of gamma-butyrolactone and a minor amount of diethyl succinate...
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4943652 |
Process for asymmetrically reducing carbonyl compounds
There is disclosed a process for asymmetrically reducing a carbonyl compound, which comprises reducing the carbonyl compound by the use of a reducing agent comprising (i) an optically active...
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4919765 |
Process for the purification of tetrahydrofuran
Tetrahydrofuran is recovered by a two stage distillation procedure from a crude hydrogenation product resulting from vapor phase hydrogenation of diethyl maleate and containing water, ethanol and a...
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4851540 |
Process for the production of biotin precursors
Process for the production of imidazole derivatives of the formula: ##STR1## wherein R 1 is an (R)- or (S)-1-phenylalkyl group, an (R)- or (S)-1-alkoxycarbonyl-1-phenylmethyl group or an (R)- or...
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4851085 |
Purification of butyrolactone
A process which comprises treating butyrolactone in at least 95% purity with an acid to convert and remove color forming impurities for product stabilization.
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4843093 |
Butyrolactone derivatives, process for production thereof and use therefor
Butyrolactone derivatives having the formula ##STR1## wherein R is a C 4 -C 10 alkyl group, which have an appetite-regulating effect, a process for their production, and compositions containing...
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4767869 |
Process for the production of gamma-butyrolactone
A process is described for the production of substantially pure gamma-butyrolactone from a feed mixture containing a major amount of gamma-butyrolactone and a minor amount of diethyl succinate...
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4659843 |
Process for preparing 3-methyl-2-butene-4-olide (4-methyl-2(5H)-furane-2-one)
The invention relates to a process for preparing 3-methyl-2-butene-4-olide by the codimerization of methylenecyclopropane with carbon dioxide (CO 2 ) in the presence of organic complex compounds of...
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4642358 |
Acyl modified polyphenylene ether composition
Acyl modified polyphenylene ether compositions are provided by combining or reacting a polyphenylene ether polymer and a compound which contains both (i) at least one acyl functional group and (ii)...
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4634780 |
Process for the production of lactones
Lactones are produced by reacting an unsaturated alcohol capable of intramolecular esterification to form a lactone ring with carbon monoxide in the presence of a protonic acid and a catalyst...
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4632784 |
Process for the preparation of 1α,23,25-trihydroxycholecalciferol-26-oic acid 23,26-lactone
The invention is directed to a process and intermediates for the preparation of 1α, 23,25-trihydroxycholecalciferol-26-oic acid 23,26-lactone.
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4625049 |
Alcohol carbonylation process using a bimetallic nickel catalyst
A process for the preparation of carboxylic acids, alcohols, aldehydes or the secondary products thereof which comprises reacting an alcohol having from one to about twenty carbon atoms with...
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4602006 |
Ynenolactone protease inhibitors
Compounds of the formula ##STR1## wherein n is 1-3; R 1 , R 2 and R 3 are the same or different and are hydrogen, lower alkyl, lower alkenyl, lower alkynyl, aryl or aryl lower alkyl wherein when...
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4596879 |
Process for producing intermediate furanones from diol derivative and thionyl chloride
A novel process for the manufacture of the furanone of the formula ##STR1## is described. In this process, a diol is firstly reacted with thionyl chloride, then the sulphite formed, optionally...
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