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8183393 |
Dye compound and dye-sensitized solar cell
A dye compound is described, which is expressed by formula (I): wherein A1, A2 and A3 each independently represent a substituted or unsubstituted 1,4-phenylene or 2,5-thiophene group, and B1 and B2...
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8154787 |
Electrochromic materials
Green electrochromic (EC) materials based on thiophene, and a green EC material based on pyrazine are disclosed. A first thiophene derivative (2,3-Di-thiophen-2-yl-thieno[3,4-b]pyrazine), which was...
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8153739 |
Antimicrobial polymers
The invention generally relates to novel polymers (SMAMPs) and their syntheses and use. The polymers exhibit promising properties of AMPs. In particularly, for example, a ring-opening metathesis...
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8138355 |
Heteroacene derivative, tetrahaloterphenyl derivative, and processes for producing the same
There are provided a heteroacene derivative having an excellent oxidation resistance and capable of forming a semiconductor active phase by a coating process, and an oxidation-resistant organic...
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8105504 |
Stabilization of organic materials
Organic materials which possess outstanding stability to oxidative, thermal or light-induced degradation comprise as stabilizers at least one compound of the formula (I) wherein the general symbols...
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8088925 |
Heteroaryl-carboxylic acid (sulfamoyl alkyl) amide-derivatives as factor Xa inhibitors
The present invention relates to compounds of the formula I, which exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders...
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8067643 |
Sulphonium salt initiators
Compounds of the formula (I), L, L′, L″, L1, L′1, L″1, L2, L′2, L″2, L3, L′3, L″3, L4, L′4, L″4, L5, L′5, L″5, L6, L′6, L″6, L7, L′7, L″7, L8, L′8 and L″8 independently of one another are hy...
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8058475 |
Substituted cyclohexylmethyl compounds
Novel cyclohexylmethyl compounds corresponding to formula I wherein R1, R2, R3, R4 and R5, have the meanings given in the description. Pharmaceutical formulations containing these compounds, as...
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8044217 |
White-emitting copolymers, representation, and use thereof
The present invention relates to white-emitting copolymers which are obtained by a combination of blue-, green- and red-emitting repeating units. The copolymers of the invention display better film...
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8013174 |
Photochromic spirodihydrophenanthropyrans
Specific photochromic spirodihydrophenanthropyrans and their use in synthetic resin materials of all kinds, particularly for ophthalmic purposes. The compounds of the invention are photochromic...
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7998965 |
Glutamate aggrecanase inhibitors
The present invention relates to modulators of metalloproteinase activity.
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7994345 |
Process for the purification of thiophenes
The invention relates to a process for the purification of thiophenes by means of precipitation. The purified thiophenes are liquid at room temperature, have a purity of at least 99.50 wt. %, and...
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7977374 |
Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (HDAC) inhibitors
The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt or stereoisomer thereof. The compounds of the present invention are inhibitors of histone...
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7977370 |
(Hetero)aryl cyclohexane derivatives
The invention relates to compounds that have an affinity to the μ-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these ...
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7973037 |
Cathepsin cysteine protease inhibitors
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for...
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7935696 |
Heterocyclic amide compounds useful as kinase inhibitors
A compound of Formula I and enantiomers, diastereomers and pharmaceutically-acceptable salts thereof. Also disclosed are pharmaceutical compositions containing compounds of Formula I, and methods...
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7897735 |
Compound having thiol anchoring group, method of synthesizing the same, and molecular electronic device having molecular active layer formed using the compound
Provided are an electron donor-azo-electron acceptor compound having a thiol-based anchoring group, a method of synthesizing the compound, and a molecular electronic device having a molecular...
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7888365 |
Tri-aryl/heteroaromatic cannabinoids and use thereof
Cannabinoid derivatives according to formula (I) are disclosed wherein, X, Y, R1, R2, and W can have the definitions provided herein. Without limitation, use of such compounds, their salts or...
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7888427 |
Latent doping of conducting polymers
Latent doping is provided wherein a conducting polymer is mixed with a dopant in solution without the doping reaction occurring unless solvent is removed. Regioregular polythiophenes are a...
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7884108 |
Certain substituted pyrazinones
Compounds of Formula I that inhibit Btk are described herein. Pharmaceutical compositions comprising at least one compound of Formula I, together with at least one pharmaceutically acceptable...
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7858658 |
Fluoro- and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof
Compounds of Formula (I), are provided where T is CHO, COR8, or C(OH)R1R2; R1 and R2 are hydrogen, optionally substituted lower alkyl, CF3, optionally substituted alkenyl, or optionally substituted...
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7838687 |
Redox-active polymers and their applications
The present invention provides a monomer comprising the structure: wherein R1 and/or R1′ are selected from the group consisting of MeO, EtO, COF3, SO4H, SO3−, SO3H, H, CHNO4S2F3, C5H4N2O6S2F6, C10...
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7829563 |
Aminoamides as orexin antagonists
The present invention relates to compounds of formula I wherein Ar1, Ar2, Ar3, n, and R1 to R8 are as defined herein and to pharmaceutically suitable acid addition salts, optically pure...
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7825154 |
Small molecule inhibitors of botulinum neurotoxins
Disclosed herein are methods of inhibiting the activity of Botulinum neurotoxin A metalloprotease with the compounds disclosed herein. Also disclosed are methods of treating, inhibiting or...
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7816558 |
Triarylcarboxylic acid derivative
Provided is a triarylcarboxylic acid derivative, or an isomer, a prodrug, a hydrate, a solvate, a polymorph, or a pharmaceutically acceptable salt thereof, represented by the following general...
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7807758 |
Chemical defunctionalization of polymeric alkylenedioxyheterocyclics
A method for preparing a defunctionalized alkylenedioxyheterocycle polymer or copolymer involves providing a polycarboxylic acid derivative functionalized alkylenedioxyheterocycle polymer or...
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7808691 |
Green electrochromic materials
Green electrochromic (EC) materials based on thiophene, and a green EC material based on pyrazine are disclosed. A first thiophene derivative (2,3-Di-thiophen-2-yl-thieno[3,4-b]pyrazine), which was...
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7745445 |
Compounds and compositions as PPAR modulators
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of...
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7732483 |
DNA-PK inhibitors
A compound of formula I: and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, wherein: R1 and R2 are independently selected from hydrogen, an optionally substituted C1-7...
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7732507 |
Spirotetrathiocarbamates and spirooxothiocarbamates
Spirotetrathiocarbamates (STOCs) or oxa substituted compounds (SOTOCs) of Formula I: Formula (I) or bisSTOC or bisSOTOC compounds of Formula II: Formula (II) wherein X1, X2, X3, X4, X5, X6, X7, and...
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7709507 |
Therapeutic fluoroethyl ureas
Compounds of the formula or a pharmaceutically acceptable salt thereof or a tautomer thereof, wherein A and B are as described herein, are useful for treating conditions afflicting mammals.
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7708908 |
Carboxylic acid-modified EDOT for bioconjugation
An electroconductive carboxylic acid functionalized monomer corresponding to Formula (I), wherein A represents a hydrogen or a carboxyl group. Polymerized monomers of Formula (I) conjugated with a...
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7705043 |
Substituted aminodicarboxylic acid derivatives having pharmaceutical properties
The invention relates to compounds of formula (I) and their salts and stereoisomers in which the variables are as defined in the description and claims, for producing medicaments used in the...
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7678831 |
Butanoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof
Compounds of the formula (I): in which R, R1 and R2 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions...
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7662478 |
Polymer and polymer light-emitting device using the same
Provided is a polymer comprising a repeating unit represented by formula (1), wherein, A1 represents a divalent group in which the bond distance ratio (bond distance of C(α)-A1/bond distance of ...
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7652064 |
AMPA receptor potentiators
The present invention relates to AMPA receptor potentiators of Formula I: formulations comprising them, methods for their use, and intermediates useful for their preparation.
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7649012 |
Compounds, pharmaceutical compositions containing same, and methods of use for same
A pharmaceutical composition comprising a pharmaceutical diluent and a compound of formula IV wherein R21=H, C1-C20 alkyl, cycloalkyl, alkenyl, aryl, arylalkyl, or alkylaryl, —CH2OR25, —...
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7625841 |
Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones
The invention relates to novel substituted thiene-3-ylsulphonylamino(thio)carbonyl-triazolin(ethi)ones of the formula (I) in which Q1, Q2, R1, R2, R3 and R4 are as defined in the disclosure, except...
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7566716 |
Imidazopyrazines as Raf inhibitor compounds
Compounds of Formula I are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using compounds of Formula I, and stereoisomers, tautomers, solvates and...
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7557104 |
Imidazopyrazines as protein kinase inhibitors
In its many embodiments, the present invention provides a novel class of imidazopyrazine compounds as inhibitors of protein and/or checkpoint kinases, methods of preparing such compounds,...
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7547725 |
Fluoro- and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof
Compounds of Formula (I), are provided where T is CHO, COR8, or C(OH)R1R2; R1 and R2 are hydrogen, optionally substituted lower alkyl, CF3, optionally substituted alkenyl, or optionally substituted...
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7538199 |
Compound having thiol anchoring group, method of synthesizing the same, and molecular electronic device having molecular active layer formed using the compound
Provided are an electron donor-azo-electron acceptor compound having a thiol-based anchoring group, a method of synthesizing the compound, and a molecular electronic device having a molecular...
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7534894 |
Biphenyloxy-acids
The present invention relates generally to substituted biphenyloxy acids (such as 4′-aryl-amido-biphenyl-4(3)-yloxy-acids and 4′-aryl-amidomethyl-biphenyl-4(3)-yloxy-acids) and methods of using the...
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7507817 |
Prostaglandin prodrugs
Novel compounds, and therapeutic methods, compositions and medicament related thereto are disclosed herein.
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7505191 |
Electrochromic monomers and polymers for a switchable window
Syntheses of a new blue EC monomer (ProDOT-MePro), and a new red EC monomer (ProDOP-Et2) are described. Two additional new types of EC monomers based on 3,4-alkylenedioxythiophene include...
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7498405 |
Halogen-substituted thienyl compounds
Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds. A representative thienyl compound has the structure
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7488856 |
Compounds based on fluoranthene and use thereof
The invention relates to fluoranthene derivatives of the general formula (I) in which R1, R2, R3 and a are each defined according to the description, with the proviso that at least one of the R1 or...
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7482376 |
Conjugated complement cascade inhibitors
The present invention is directed to conjugated complement cascade inhibitors, and a method of treating a patient using a conjugated complement cascade inhibitor.
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7482472 |
Substituted isoindoles and their use
The invention relates to coagulation of the blood. Disclosed are novel compounds of formula (I), a method for the production of these compounds, pharmaceutical compositions containing them, and...
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7468437 |
Phenyl pyrrolidine ether tachykinin receptor antagonists
The present invention is directed to certain phenyl pyrrolidine ether compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular...
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