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7619100 |
Physiologically active substances
The present invention relates to a compound represented by the formula (I):
(wherein, R 3 , R 6 , R 7 and R 21 are the same as or different from one another and each represents a hydroxyl...
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7601852 |
Macrocyclic kinase inhibitors
A compound having a structure according to formula I
wherein R 1 , R 2 , R 3 , R 4 , and R 5 are as defined herein, are useful as kinase inhibitors.
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7569535 |
11-methyl-13-tridecanolide, 12-methyl-14-tetradecanolide and 13-methyl-15-pentadecanolide, perfume compositions containing the same, and process for production of compounds including the same
Among the compounds represented by the general formula (1),
(in the formula, n is an integer of 7 to 13)
in particular, 11-methyl-13-tridecanolide of which n=8,...
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7553859 |
Macrocycles for the treatment of cancer
The present invention relates to new Macro-cycles of Formula (I), and their use for the treatment of cancer.
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7550503 |
Physiologically active substances
The present invention relates to a compound represented by the formula (I):
(wherein, R 3 , R 6 , R 7 and R 21 are the same as or different from one another and each represents a hydroxyl...
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7476647 |
Ether lactone
The invention relates to the ether lactone of formula (I) which is characterized by interesting and original odor characteristics, which diffuses extremely well and is suitable for use as a...
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RE39991 |
Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
A compound having the following formula:
wherein R 3 and M are defined herein, and processes therewith.
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7314942 |
Methylenelactones syntheses in supercritical fluids
Alpha-methylenelactone is produced from butyrolactone and valerolactone by the addition of formaldehyde in a supercritical fluid.
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7183420 |
Method for the preparation of 11(12)-pentadecen-15-olides
The invention relates to an improved method for the preparation of 11(12)-pentadecen-15-olides.
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7122686 |
Analogs of discodermolide and dictyostatin-1, intermediates therefor and methods of synthesis thereof
A compound of the following structure:
wherein R 1 is H, an alkyl group, an aryl group, an alkenyl group, an alkynyl group, or a halogen atom;
R 2 is H, an alkyl group, an aryl group,...
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7105684 |
Lactone compounds
An object of the present invention is to provide a novel monomer compound having a lactone structure which gives polymers having more excellent feature as resist material, etc. The present...
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7105268 |
Polymer for photoresist and resin compositions therefor
A polymeric compound for photoresist of the invention includes at least one monomer unit represented by following Formula (I):
wherein R 1 , R 2 , R 3 , R 4 and R 5 are the same or different...
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7098347 |
Process for the preparation of 1-hydroperoxy-16-oxabicyclo[10.4.0]hexadecane
Process for the preparation of 1-hydroperoxy-16-oxabicyclo[10.4.0]hexadecane (DDP-OOH), wherein 13-oxabicyclo[10.4.0]hexadec-1(12)-ene (DDP) and hydrogen peroxide are reacted in a diluent in the...
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7030249 |
Process for converting α-angelica lactone to 5-methyl-N-alkyl-2-pyrrolidone using alkyl amines
This invention relates to a process for producing 5-methyl-N-alkyl-2-pyrrolidone by a) reacting α-angelica lactone with alkyl amines and b) hydrogenating the products of step (a) in the presence...
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6960573 |
Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same
Compounds expressed by the following general formula (1),
[wherein, R 01 and R 02 are each independently a hydrogen atom or a protecting group for a hydroxyl group; Z is one out of the...
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6960693 |
Oxidation reaction process catalyzed by phase-transfer catalyst controlling reaction
The present invention relates to an oxidation reaction catalyzed by a reaction controlled phase-transfer catalyst having the general formula of [R 1 R 2 R 3 R 4 N] x H y [A] or Q m MO 3 (L). The...
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6919464 |
Synthetic derivatives of 21-butenyl and related spinosyns
Macrolide compounds produced by synthetic modification of factors produced by NRRL 30141 have insecticidal and acaricidal activity and are useful intermediates for preparing additional insecticidal...
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6914109 |
Process for the preparation of 15-pentadecanolide
The invention relates to a process for the preparation of 15-pentadecanolide by hydrogenating 15-pentadecenolide and to its use.
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6911547 |
Process for the preparation of bicyclic diketone salts
The present invention relates to a process for the preparation of bicyclic 1,3-diketone salts of formula I
wherein R 1 , R 2 , R 3 and R 4 are each independently of the others hydrogen or C...
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6710188 |
Chemically amplified resist, polymer for the chemically amplified resist, monomer for the polymer and method for transferring pattern to chemically amplified resist layer
Chemically amplified resist is produced on the basis of vinyl polymer having 3-oxo-4-oxabicyclo[3.2.1]octane-2-yl group expressed by general formula (1) where each of L 1 , L 2 , L 3 , L 4 , L 5...
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6680055 |
Mycolactone and related compounds, compositions and methods of use
The present invention provides, inter alia, polyketide macrolides including a polyketide macrolide of the structure wherein R 1 -R 5 are the same or different and each is independently selected...
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6649776 |
Methylenelactone synthesis in supercritical fluids
Alpha-methylenelactones are produced from butyrolactone and valerolactone by the addition of formaldehyde in a supercritical fluid in the presence of a catalyst and a phase transfer agent.
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6639075 |
Lactam-aldehyde compound and process of preparing same
A lactam-aldehyde compound represented by the formula (I) shown in the specification. The lactam-aldehyde compound may be prepared by subjecting a lactone-imine compound represented by formula...
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6635671 |
Compounds which affect mRNA stability and uses therefor
Compounds which induce degradation of mRNA which contains one or more mRNA instability sequences are provided for use as pharmaceuticals, e.g. for use in the prophylaxis or treatment of diseases...
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6627763 |
Compounds having protected hydroxy groups
The present invention relates to compounds with protected hydroxy groups of formula (I) These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for...
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6617304 |
Method for producing macrocyclic lactone
The invention discloses a method for the production of a macrocyclic lactone represented by a formula (2), which comprises subjecting a hydroxycarboxylic acid ester represented by a formula (1) to...
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6531615 |
Process for the oxidation of cyclohexanone to &egr -caprolactone
This invention relates to a composition comprising antimony trifluoride and silica, a method for the preparation of said composition and use of said composition as a catalyst in a process for the...
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6531616 |
Process for the preparation of a-methylenelactones and a-substituted hydrocarbylidene lactones
This invention pertains to a process for making α-methylenelactones and α-substitute hydrocarbylidene lactones. More specifically, the present invention obtains high yields of...
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6531460 |
Vitamin D, derivatives and remedies for inflammatory respiratory diseases containing the same
Compounds expressed by the following general formula (1), The compounds can be used as active ingredients of treating agents for inflammatory respiratory diseases, malignant tumors, rheumatoid...
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6458972 |
Process for the preparation of macrocyclic esters
Macrocyclic ester compounds can be prepared from oligoesters by thermal cleavage in the presence of a thermostable benzene derivative.
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6437151 |
Erythromycins and process for their preparation
Erythromycins, particularly ones with novel C-13 substituents R1 (e.g. C 3 -C 6 cycloalkyl or cycloalkenyl groups) are prepared by fermenting suitable organisms in the presence of R 1 CO 2 H. A...
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6369099 |
Method of locking 1 α-OH of vitamin D compounds in axial orientation
A method of modifying or altering the structure of a 1α-hydroxylated vitamin D compound to increase its biological activity by altering the conformational equilibrium of the A-ring to favor a...
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6323347 |
Catalyst for preparing lactone and a method for preparing lactone
The present invention relates to a catalyst for preparing a lactone, which is prepared by supporting a cupric compound, a zinc compound and at least one alkaline earth metal compound on the...
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6320045 |
Process for the reduction of oxiranyl epothilones to olefinic epothilones
The invention as claimed is directed to a process for making an epothilone having the following structures ##STR1## from ones having an oxiranyl moiety, by reacting a compound having the latter...
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6313318 |
Process for the preparation of α-methylene lactones
This invention concerns a process for the addition of formaldehyde to the α carbon atom of lactones for the production of α-methylenelactones, and specifically α-methylene-γ-butyrolactone.
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6307065 |
Processes for producing epsilon caprolactones and/or hydrates and/or esters thereof
This invention relates in part to processes for producing one or more substituted or unsubstituted epsilon caprolactones and/or hydrates and/or esters thereof which comprise subjecting one or more...
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6255276 |
Odorant compositions containing macrocycles and processes for manufacturing the same
The invention is concerned with odorant compositions which contain macrocycles, namely 15- to 17-membered compounds of the formula: ##STR1## wherein the dotted line signifies an optional additional...
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6232474 |
Process for the preparation of α-methylenelactones and α-substituted hydrocarbylidene lactones
This invention pertains to a process for making α-methylenelactones and α-substituted hydrocarbylidene lactones. The present invention obtains high yields of α-methylene-γ-butyrolactone by...
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6229023 |
Process for cooxidizing organic compounds, process for producing epoxy compounds and process for producing esters or lactones
According to the inventive co-oxidation process of organic compounds, (A) a compound selected from (A1) a compound having a non-aromatic ethylenic bond and (A2) a ketone or an alcohol corresponding...
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6225281 |
Cis-isoambrettolide and use thereof
Manufacture of a molecule which is of important olfactory interest for perfumers. This molecule belongs to the group of macrocyclic lactones with a musk odor. The manufacturing process consists in...
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6207839 |
Process for preparing compositions useful as intermediates for preparing lubricating oil and fuel additives
A process for reacting olefinic compounds, certain carboxylic reactants, and aldehydes or ketones and products prepared by the process. The compositions of the process are useful as intermediates...
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6156910 |
ε-Caprolactone, process for producing the same, polycaprolactone obtained therefrom, and process for producing the polycaprolactone
The present invention provides ε-caprolactone having a purity of at least 99.8% by weight and a total concentration of not more than 200 ppm based on area ratio of components having a relative...
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6150538 |
Process for manufacturing cis-isoambrettolide and use thereof
Manufacture of a molecule which is of important olfactory interest for perfumers. This molecule belongs to the group of macrocyclic lactones with a musk odor. The manufacturing process consists in...
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6140514 |
Process for the preparation of macrocyclic esters or lactones
A process for the preparation of macrocyclic esters or lactones in a two-stage reaction, which entails effecting linear oligomerization of monomers having a number of carbon atoms corresponding to...
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6025350 |
C-4" substituted macrolide antibiotics
This invention relates to compounds of the formula ##STR1## and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are potent antibacterial and antiprotozoal agents that may...
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RE36493 |
Fragrant macrocyclic lactones
Perfuming ingredients which include at least one macrolide of formula ##STR1## having a double bond in one of the positions indicated by the dotted lines and wherein the symbol R represents a...
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6008185 |
Macrocyclic lactones as musk fragrance enhancers
Compounds of the formulae ##STR1## in which R is hydrogen or methyl, and the dashed lines represent an additional bond in the 11- or 12-position, have extraordinary olfactory properties.
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5981769 |
Process for preparing 1,6- hexanediol and caprolactone
1,6-hexanediol and ε-caprolactone are prepared from a carboxylic acid mixture comprising adipic acid, 6-hydroxycaproic acid and small amounts of 1,4-cyclohexanediols which is obtained as a...
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5972237 |
Use of heterocyclic compounds as activators for inorganic peroxy compounds
Heterocyclic compounds I R 1 --X--L (I) where L is a cyclic carbamate residue, a lactonoxy residue or a lactam residue, X is an...
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5948770 |
Antifungal macrolides and their synthesis
There are disclosed novel antifungal macrolides of the formula ##STR1## compositions containing said compounds, methods of using said compounds and a method for synthesizing the compounds.
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