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7576213 Vinylogous 4H-pyrones and their use in promoting plant growth  
A hitherto unknown class of chemical compounds, 2H-furo[2,3-c]pyran-2-ones including derivatives and analogues thereof are disclosed herein. Methods for making compounds within said class are...
7544717 2-amino- and 2-thio- substituted 1,3-diaminopropanes  
Disclosed are compounds of the formula: where variables Q, Z, X, R 15 , R 2 , R 3 , and R c are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are...
7495111 Compounds useful as serotonin inhibitors and 5-HT1A agonists and antagonists  
3-Amino chroman and 2-amino tetralin derivatives and compositions containing such compounds are disclosed. Such compounds are useful for modulating activity of a 5-HT 1A receptor (agonizing or...
7488494 Compositions and therapeutic methods involving isoflavones and analogues thereof  
Isoflavone compounds are described and recommended as therapeutic agents. Exemplified and preferred compounds are (a). Indications show compounds have good competitive binding to estrogen...
7476673 Disubstituted chalcone oximes as selective agonists of RARγ retinoid receptors  
Compounds of the formula where the variables are as defined in the specification, are useful for preventing or treating emphysema and related pulmonary conditions of mammals and other diseases...
7468360 Therapeutic amides and related compounds  
Disclosed herein is a compound having a structure: Therapeutic methods, compositions, and medicaments relating thereto are also disclosed.
7435455 Dihydrocoumarin derivative, liquid crystal composition containing the same, and liquid crystal display device  
A dihydrocoumarin ring-containing compound of the invention is represented by the following formula (1): wherein R represents hydrogen or an alkyl; A 1 to A 3 each represents...
7414143 Process for the preparation of 4,4-dimethyl-6-ethynylthiochroman  
An improved process for the preparation of key intermediates for tazarotene, 4,4-dimethyl-6-ethynylthiochroman, is provided comprising (a) reacting 4,4-dimethyl-6-acetylthiochroman of the formula ...
7318991 Heterocycle-bearing onium salts  
The present invention relates to a heterocycle-containing onium salt useful as, for example, a cationic photopolymerization initiator and an acid generator for a chemically amplified resist, and...
7301705 Alicyclic compound for optical material  
The alicyclic compound of the present invention has a five- or more membered ring structure having an epithioethylene linkage and/or an epidithioethylene linkage, and has tow or more sulfur atoms...
7294650 Benzothiophen and thiochrone containing phenethanolamine derivatives for the treatment of respiratory disorders  
Compounds of formula (I): and salts, solvates, and physiologically functional derivatives thereof, useful for the prophylaxis or treatment of a clinical condition for which a selective β 2...
7259271 Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation  
Compounds of formula I: where R 1 , R 2 and R 3 are the same or different and signify hydrogens, halogens, alkyl, alkylaryl, alkyloxy, hydroxy, nitro, amino, alkylcarbonylamino, alkylamino or...
7230121 Sulfoniun salts, methods for their preparation and use thereof as photoinitiators for radiation curable systems  
The present invention relates to sulfonium salts, to methods for their preparation and to radiation curable compositions containing them as photoinitiators.
7223774 Benzamide 2-hydroxy-3-diaminoalkanes  
The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme...
7196081 Compounds with hydroxycarbonyl-halogenoalkyl side chains  
The present invention provides a compound consisting of a moiety and a group chemically bonded to said moiety, wherein said moiety contains a compound having low activity following oral...
7138411 Substituted benzopyran derivatives for the treatment of inflammation  
A class of benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes, and analogs thereof, is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular...
7109353 Process for preparing 5,6-dihydro-4-(S)-(ethylamino)-6-(S) methyl-4H-thieno[2,3b]thiopyran-2-sulphonamide-7,7-dioxide HCl  
The present invention relates to an improved process for the preparation of 5,6-dihydro-4-(S)-(ethylamino)-6-(S)methyl-4H-thieno[2,3b]th iopyran-2-sulphonamide-7,7-dioxide hydrochloride of formula...
7101998 Fused ring compounds, and their use as cationic photoinitiators  
Compounds of formula (I): [in which: R 1 represents a direct bond, an oxygen atom, a group >CH 2 , a sulphur atom, a group >C═O, a group —(CH 2 ) 2 — or a group of formula —N—R...
7074819 Benzopyran or thiobenzopyran derivatives  
The present invention relates to a novel benzopyran or thiobenzopyran derivative represented by formula (1): pharmaceutically acceptable salt or stereoisomer thereof, in which X, R 1 , R 2 , R 3 ,...
7060425 Color photographic material  
A color photographic material is described containing a compound of formula (I) wherein, if n=1, R 1 is, inter alia, a radical of formula (II), and, if n=2, R 1 is unsubstituted or C 1 –C 4...
7053115 Crystalline form of dorzolamide hydrochloride  
The present invention relates to a novel crystalline form of dorzolamide hydrochloride, to processes for its preparation and a pharmaceutical composition containing it.
7045514 Therapeutic heterocyclic compounds  
Provided herein is a compound having the formula (I): Wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety,...
7030250 Process for obtaining 4-(N-alkylamino)-5,6-dihydro-4H-thien-(2,3-b)-thiopyran-2-sulfonamide-7,7-dioxides and intermediates  
The process for obtaining 4-(N-alkylamino)-5,6-dihydro-4H-thien-(2,3-b)-thiopyran-2-su lfonamide-7,7-dioxides (I) wherein R 1 is H or C 1-5 alkyl, and R 2 is C 1-5 alkyl, starts from the...
7018802 Electrochemiluminescent enzyme immunoassay  
Electrochemiluminescent-labels and enzyme substrates, which preferably are conjugated, are used in immunoassays and electrochemiluminescence is generated catalytically. In conventional...
6916831 Flavone acetic acid analogs and methods of use thereof  
Compounds are described having a structure according to Formula I or Formula II: wherein: X is selected from the group consisting of O, NH, and S; Y is selected from the group consisting of O...
6844366 Sulfonamide hydroxamates  
This invention relates to certain sulfonamide derivatives that are inhibitors of procollagen C-proteinase, pharmaceutical compositions containing them, methods for their use and methods for...
6818666 Bi-aromatic compounds linked via a heteroethylene radical, and pharmaceutical and cosmetic compositions using them  
Bi-aromatic compounds linked via a heteroethynylene radical are provided along with pharmaceutical and cosmetic compositions containing these compounds and methods for their use.
6809206 Method for acylating cyclic compounds  
The method of this invention prepares acylated cyclic compounds by contacting phenyl esters as acylating agents with cyclic compounds in the presence of a cyanide or fluoride catalyst.
6806288 Substituted benzopyran derivatives for the treatment  
A class of benzopyran, derivatives is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I′ wherein X, A 1 , A 2 , A 3 ,...
6803129 Organic light emitting diode and organic luminescent materials thereof  
The present invention relates to an organic light emitting diode (OLED) device, comprising an anode disposed on a substrate, an organic EL layer disposed on the anode and a cathode disposed on the...
6750346 Stable near-infrared (NIR) marker dyes based on benzopyrylium-polymethines  
The disclosure is directed to so-called laser-compatible NIR marker dyes based on polymethines for use in optical, in particular, fluorescence optical determination and detection methods, for...
6680332 Substituted 5-oxo-5,6,7,8-tetrahydro-4H-1-benzopyrans and benzothiopyrans and the use thereof as potentiators of AMPA  
Disclosed is a method for treating a disorder responsive to the positive modulation of AMPA receptors in animals suffering therefrom, comprising administering to an animal in need thereof a...
6677338 Serotonin transport inhibitors  
The present invention relates to the therapeutic use of non-amine tropane analogues that bind to the SERT to treat neuropsychiatric disorders.
6677460 Aromatic carboxylic acid bicyclic sulfur compounds  
An aromatic carboxylic acid bicyclic sulfur compound of the formula (II): wherein X 1 is a C 1 to C 4 alkyl, a halogen, a C 1 to C 4 haloalkyl, a C 2 to C 4 alkoxyalkyl, a C 1 to C 4 ...
6645951 Benzopyran or thiobenzopyran derivatives  
The present invention provides novel benzopyran compounds, pharmaceutically acceptable salts thereof and stereoisomers thereof where the benzopyran compounds of the invention are compounds...
6635650 Substituted dimeric compounds  
The invention relates to compounds of formula (I): A-G 1 -Cy-G 2 -Cy-G 3 -B (I) wherein: A represents NR 1 C(Q)R 2 , C(Q)NR 2 R 3 or NR 1 C(Q)NR 2 R 3 , B represents NR 1 C(Q)R 2 , C(Q)NR 2 R 3...
6630506 Bicyclic acyl guanidine sodium/proton exchange inhibitors and method  
Acyl guanidines are provided which are sodium/proton exchange (NHE) inhibitors which have the structure wherein n is 0 to 4; X is a bond, O, S, SO, SO 2 , CO, or NR 7 ; Y is a bond, O, S, SO,...
6610733 Optically active chroman and thiochroman derivatives  
The present invention includes a compound having the following general formula (1): in which x represents an oxygen atom or a sulfur atom, m represents an integer of 2 to 14, and n represents an...
6596758 Benzopyrans and benzoxepines, pharmaceutical compositions comprising them and preparation process  
The present invention relates to benzopyrans and benzoxepines of formula (I), wherein X, A, R 1 , R 2 and (R) p have the meanings as given in claim 1, which can be used in the treatment of...
6586460 Heteroarotinoids containing urea or thiourea linker  
Compounds, known as heteroarotinoids, having varying abilities to inhibit growth of certain cancerous cells, induce normal cell differentiation, and induce apoptosis or death of cancerous cells, of...
6555571 3-methyl -chromane or thiochromane derivatives  
The present invention relates to 3-methyl-chromane or thiochromane derivatives, pharmaceutically acceptable salts, stereoisomers or hydrates thereof, and an anti-estrogenic pharmaceutical...
6552068 3-ethyl-, 3-propyl- or 3-butyl-chroman and thiochroman derivatives  
A compound having the following general formula (1): in which R 1 represents an ethyl group, etc.; R 2 represents a hydrogen atom, etc.; R 3 represents a C 1 -C 5 perhalogenoalkyl group,...
6552069 3-methyl-chroman and -thiochroman derivatives  
The present invention provides a compound having the following general formula (1): in which R 1 represents a hydrogen atom, etc.; R 2 represents a C 3 -C 3 perhalogenoalkyl group, etc.; each...
6514967 Compound for preparing medicines for treating pathologies involving extracellular glutamate, and methods for obtaining same  
The invention relates to compounds of the following general formula (I): in which: R 1 and R 2 represent a hydrogen atom, or form a ring, especially a benzene ring, R 3 represents a hydrogen...
6482950 Squarylium compounds, and processes and intermediates for the synthesis of these compounds  
Squarylium compounds of the formula: wherein Q 1 and Q 2 are each independently a pyrylium, thiopyrylium, selenopyrylium, benzpyrylium, benzthiopyrylium or benzselenopyrylium nucleus, and R 1 ...
6479670 Selective retinoid acid receptor agonists  
This invention relates to new selective retinoid acid receptor agonists of formula I wherein the symbols are as defined in the specification to their pharmaceutically acceptable salts,...
6479671 Process for producing optically active chromene derivative  
A process for producing a compound of the formula (II): (wherein R 1 , R 2 , R 3 and R 4 are each independently hydrogen, alkyl, alkoxy or the like, R 5 is alkyl or alkoxyalkyl, A is O or S,...
6440899 Cyclohexenonedioxothiochromanoyl derivatives  
Cyclohexenonedioxothiochromanoyl derivatives of the formula I where X is oxygen, sulfur, S═O, S(═O) 2 , CR 4 R 5 , C═O or C═NR 6 , the other substituents are as defined in the...
6441196 Processes and novel intermediates for 11-oxa prostaglandin synthesis  
Novel processes and intermediates useful in the preparation of 11-oxa prostaglandin analogs are disclosed.
6350875 Synthesis of cyclooctatetraene derivatives and their use as electron transporters in organic light emitting diodes  
The synthesis of asymmetric tetrasubstituted cyclooctatetraenes (“COTs”) and the use of said compounds in organic light emitting diodes is reported, wherein said COTs represent a class of wide...
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