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8802082 Rhodamine derivatives for photodynamic diagnosis and treatment  
Compositions and methods for reducing or preventing graft-versus-host disease associated with allogeneic stem cell transplantation are described. A method includes harvesting hematopoietic cells...
8722574 Thermal imaging members and methods  
There are described thermal imaging members and thermal imaging methods utilizing unsymmetrical rhodamine compounds. The rhodamine color-forming compounds exhibit a first color when in a...
8518915 Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases  
The invention relates to pharmacology and medicine, in particular to a class of mitochondrially-addressed compounds which can be used in the pharmaceutical compositions of medicinal agents...
8435800 Activated labeling reagents and methods for preparing and using the same  
The present invention relates in general to labeling reagents useful for labeling biomolecules. In particular, the invention provides activated labeling reagents having the formula L-Ph, wherein L...
8436170 Xanthene dyes comprising a sulfonamide group  
The present invention relates to fluorescent dyes in general. The present invention provides a wide range of fluorescent dyes and kits containing the same, which are applicable for labeling a...
8420402 Compounds related to assays  
The present invention is generally directed to thiol quantitation assays, methods of performing the assays, and compounds used in the assays. It is more specifically directed to assays that...
8409564 Rhodamine derivatives for photodynamic diagnosis and treatment  
The present invention relates to the use of the photoactivable derivatives for the photodynamic treatment for the selective destruction and/or inactivation of immunologically reactive cells...
8383672 Halogenated rhodamine derivatives and applications thereof  
Methods for treating a bacterial infection in a tissue sample are described. Tissue samples that are harvested from a patient may be infected with bacteria. A rhodamine compound is mixed with the...
8143069 Fluorescent probe and method of measuring hypochlorite ion  
A compound represented by the following general formula (II): wherein R21 represents hydrogen atom or one to four monovalent substituents substituting on the benzene ring, and when R21 represents...
8129193 Thiol quantitation assays and related methods  
The present invention is generally directed to thiol quantitation assays, methods of performing the assays, and compounds used in the assays. It is more specifically directed to assays that...
8101655 Fluorescent dyes and complexes  
A fluorescent dye comprising a xanthene-derived fluorophore having the formula (I) wherein R1, R2, R3, R4, R5 and R6 are independently selected from H, alkyl, alkoxy, alcohol, ether, alkenyl,...
7985865 Phase change ink formulations, colorant formulations, and methods of forming colorants  
A compound having the formula wherein R1, Z, and the carbonyl can be comprised by a common ring, wherein R1 comprises a chromophore that absorbs light from the visible wavelength range, and...
7745645 Sulfonamide derivatives of xanthene compounds  
Compounds having the general of formula I and/or formula II wherein R1 and R2 are the same or different and are independently selected from the group consisting of —H, —C1-C18-alkyl or...
7704667 Dyes and use thereof in imaging members and methods  
There are described novel rhodamine dye compounds and imaging members and imaging methods, including thermal imaging members and imaging methods, utilizing the compounds. The dye compounds exhibit...
7674918 Fluorescent dyes and complexes  
A fluorescent dye comprising a xanthene-derived fluorophore having the formula (I) wherein R1, R2, R3, R4, R5 and R6 are independently selected from H, alkyl, alkoxy, alcohol, ether, alkenyl,...
7667051 Method of obtaining urethane-protected N-carboxyanhydrides of alpha amino acids  
The invention relates to a method of preparing urethane-protected N-carboxyanhydrides of alpha amino acids. The inventive method enables the synthesis of urethane-protected N-carboxyanhydrides of...
7560574 Halogenated rhodamine derivatives and applications thereof  
Compounds of formula (I) wherein: one of R1, R2, R3, R4 and (R10)n represents halogen and each remaining R1, R2, R3, R4 and R10 group is independently selected from hydrogen, halogen, amino,...
7534902 Fluorescence assays with improved sensitivity  
Latent fluorescent compounds, comprising a fluorescent molecule with one or more blocking groups attached and optionally one or more urea-containing groups are provided. The urea-containing group...
7432298 Fluorescent polymeric materials containing lipid soluble rhodamine dyes  
Fluorescent polymeric materials are disclosed comprising a polymer and one or more lipid soluble rhodamine dyes. The materials are especially useful in the preparation of multicolored...
7399639 Sensors, and methods of making and using the same  
The present invention is directed, in part, to sensors for detecting metal ions, and methods of making and using the same.
7282575 Functional peptide nucleic acid monomer and process for producing the same  
A compound represented by the general formula (I) below: In the formula, A is as defined in the specification and B denotes where n is an integer of 1 to 4, and a process for producing the above...
7102005 Compositions and methods for detection and isolation of phosphorylated molecules  
The present invention relates to phosphate-binding compounds that find use in binding, detecting and isolating phosphorylated target molecules including the subsequent identification of target...
7083667 Colorant compound, ink, ink tank, recording unit, recording apparatus and recording process  
Disclosed herein is a colorant compound represented by the following general formula (1): wherein R1 and R2 are the same or different from each other and denote a linear alkyl group having 1 to 4...
7049073 Double stranded nucleic acid biochips  
This invention describes a new method of constructing double-stranded DNA (dsDNA) microarrays based on the use of pre-synthesized or natural DNA duplexes without a stem-loop structure. The...
6967250 Energy transfer dyes  
Energy transfer dyes, their preparation, and their use as labels in biological systems is disclosed. The dyes are preferably in the form of cassettes which enable their attachment to a variety of...
6916925 Dye labeled imidazoquinoline compounds  
Dye labeled imidazonaphthyridine, imidazopyridine and imidazoquinoline compounds having immune response modulating activity are disclosed. The compounds arc useful, inter alia, for determining the...
6756231 Diaminorhodamine derivative  
A compound represented by the following formula (I) or (II): wherein, in the formula (I), R1, R2, R3, and R4 independently represent methyl group or ethyl group; and in the formula (II), R5, R6,...
6713622 4,7-dichlororhodamine dye labeled polynucleotides  
A set of 4,7-dichlororhodamine compounds useful as fluorescent dyes are disclosed having the structures wherein R1-R6 are hydrogen, fluorine, chlorine, lower alkyl, lower alkene, lower alkyne,...
6608213 Fluorescence-labeled probe for DNA and a fluorescence-labeled plasmid  
This invention provides a precursor compound of a novel fluorescence-labeled probe for DNA, prepared by covalent binding of a fluorescent substance such as fluorescein isothiocyanate, wherein a...
6566030 Methods and compositions for imaging acids in chemically amplified photoresists using pH-dependent fluorophores  
A method of imaging acids in chemically amplified photoresists involves exposing to radiation a chemically amplified photoresist comprising a pH-dependent fluorophore. Upon exposure to radiation,...
6482938 Compounds having energy transfer function and method for DNA base sequencing by using the same  
Disclosed are compounds having two kinds of reporters that can be a donor and an acceptor for energy transfer, for example, fluorescent groups, and having a 2′, 3′-dideoxyribonucleotide residue or...
6455271 Identification of novel antimicrobial agents using membrane potential indicator dyes  
Novel screening methods for identifying antimicrobial agents involving use of membrane potential indicator dyes are provided.
6201134 Diaminorhodamine derivatives  
A compound represented by the following general formula:wherein R1 and R2 represent amino groups present at adjacent positions each other on the phenyl ring; R3, R4, R5 and R6 independently...
6187913 Covalently crosslinked oligonucleotides, preparation method and synthon which is of use in the method  
A double- or single-stranded oligonucleotide comprising one or more respectively inter- or intra-oligonucleotide covalent cross-linkages, wherein the or each covalent linkage consists of an amide...
6162931 Fluorinated xanthene derivatives  
The family of dyes of the invention are fluoresceins and rhodols that are directly substituted on one or more aromatic carbons by fluorine. These fluorine-substituted fluorescent dyes possess...
6130101 Sulfonated xanthene derivatives  
The present invention describes xanthene dyes, including rhodamines, rhodols and fluoresceins that are substituted one or more times by a sulfonic acid or a salt of a sulfonic acid. The dyes of...
6080852 4,7-dichlororhodamine dyes  
A set of 4,7-dichlororhodamine compounds useful as fluorescent dyes are disclosed having the structures ##STR1## wherein R1 -R6 are hydrogen, fluorine, chlorine, lower alkyl, lower alkene, lower...
5998632 Derivatized Rhodamine dye and its copolymers  
Disclosed are the Rhodamine B esters of hydroxy C2 -C6 lower alkyl acrylates. Specifically, the hydroxy lower alkyl radical is a linear hydroxy lower alkyl radical having the hydroxy group...
5846737 Conjugates of sulforhodamine fluorophores with enhanced fluorescence  
The invention describes useful conjugates of sulforhodamine, wherein the conjugated substance and the fluorophore are separated by an alkanoic acid spacer that is attached to the fluorophore via a...
5847162 4, 7-Dichlororhodamine dyes  
A class of 4,7-dichlororhodamine compounds useful as fluorescent dyes are disclosed having the structure ##STR1## wherein R1 -R6 are hydrogen, fluorine, chlorine, lower alkyl lower alkene, lower...
5777133 Synthesis of 1, 2-dioxetanes and intermediates therefor  
Compounds having the formula: ##STR1## wherein T is a polycycloalkylidene group (e.g., adamant-2-ylidene); R is a C1-20 alkyl, aralkyl or cycloalkyl group; and Y is a fluorescent chromophore (eg.,...
5773460 Rhodamine derivatives for photodynamic therapy of cancer and in vitro purging of the leukemias  
The present invention relates to novel photoactivable rhodamine derivatives for enhancing high quantum-yield production and singlet oxygen generation upon irradiation with light while maintaining...
5741662 Direct stain specific binding assays for microorganisms  
The present invention provides specific binding solid phase assay methods and kits for the detection of the presence or absence of a microorganism by directly staining the microorganism and...
5714342 Compositions for the detection of protease in biological samples and methods of use therefo  
The present invention provides for novel reagents whose fluorescence increases in the presence of particular proteases. The reagents comprise a characteristically folded peptide backbone each end...
5616729 Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers  
Triggerable dioxetanes with a fluorescent substituent bonded or tethered in the dioxetane so as to produce fluorescence from the group are described. The compounds are of the formula: ##STR1##...
5576436 Fluorescent ligands  
Conjugates of fluorescent labels with specific, selective, and high affinity ligands for receptors have been synthesized and used to directly measure binding to receptors.
5516864 Fluorescent ion-selective diaryldiaza crown ether conjugates  
This invention describes novel sensors for ions that are based on the combination of xanthylium-based dyes with metal-binding N,N'-diaryldiaza crown ethers. These sensors are primarily useful for...
5459268 Xanthylium dyes that are well retained in mitochondria  
The dyes of the present invention are fluorescent substituted 3',6'-diaminoxanthenes and their reduced analogs 3',6'-diaminodihydroxanthenes, which are oxidized to the fluorescent form of the dye...
5453517 Reactive derivatives of bapta used to make ion-selective chelators  
The invention relates to fluorescent and/or reactive derivatives of 1,2-bis-(2-aminophenoxyethane)-N,N,N',N'-tetraacetic acid (BAPTA) according to the formula: ##STR1## where at least one of W and...
5410053 Rhodamine derivatives  
There are described rhodamine derivatives of the formula ##STR1## where R1, R2, R3 and R4 are each hydrogen or substituted or unsubstituted C1 -C4 -alkyl, or R2 is paired off with R5 or R4 with R6...

Matches 1 - 50 out of 102 1 2 3 >