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8101782 |
Compounds that inhibit cholinesterase
Compounds that inhibit cholinesterase activity and, upon hydrolysis release a pharmacologically active agent. The compounds of the invention are employed in methods to treat an individual. The...
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8080674 |
Preparation of polymer-free R-(+)-α-lipoic acid magnesium salt
R-α-Lipoic acid and its homologs are converted to their magnesium salts in the presence of a reduced form of the acid, dihydro-(+)-lipoic acid in the case of R-α-lipoic acid itself. The reduced f...
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7919635 |
Substituted phenylsulfur trifluoride and other like fluorinating agents
Novel substituted phenylsulfur trifluorides that act as fluorinating agents are disclosed. Also disclosed are methods for their preparation and methods for their use in introducing one or more...
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7601848 |
Multifunctional reagent for the synthesis of thiol modified oligomers
The invention relates to compounds of formula (I), wherein Z represents a hydrocarbon with 2 to 28 C atoms, wherein Z can also comprise elements N, O, P, S, Si and halogen as heteroatoms, R1 and R2...
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7385067 |
Process for the preparation of compounds having a CF2O bridge
The invention relates to a process for the preparation of compounds containing at least one —CF2—O— bridge in the molecule, in which a) an acid is added onto at least one ketene dithi...
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7232915 |
Process for the synthesis of 1,3-diols
An improved process for the preparation of cis-1,3-diols is described where a beta hydroxy ketone is treated with a trialkylborane or dialkylalkoxyborane or a mixture of a trialkylborane and a...
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7208169 |
Biphenyl carboxamides
The invention relates to novel biphenylcarboxamides of the formula (I) in which R1, R2, m, n, R3, Y and A are as defined in the disclosure, to a plurality of processes for preparing these...
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7169942 |
Cannabinoid derivatives, methods of making, and use thereof
1′-substituted cannabinoid derivatives of delta-8-tetrahydrocannabinol, delta-9-tetrahydrocannabinol, and delta-6a-10a-tetrahydrocannabinol that have affinity for the cannabinoid receptor type-1 (...
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7115651 |
Macrocycles and uses thereof
The present invention relates to compounds having the structure (and pharmaceutically acceptable derivatives thereof) wherein R0–R4, Z, X, A—B, D—E, G—J, and K—L are as defined herein, the synth...
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7091344 |
Infrared chromophores
An infrared dye, characterized in that the dye comprises of Formulae 1 to 5
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6900338 |
Scavenger compounds
The present invention provides novel compounds having scavenging and anti-ROS properties and pharmaceutical composition comprising these compounds for treatment of conditions associated with...
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6787062 |
Producing liquid crystals with CF2O bond
The invention relates to a process for the preparation of compounds having at least one —CF2O— bridge in the molecule, which comprises initially reacting a bis(alkylthio)carbenium salt with a com...
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6664287 |
Antioxidants
This invention comprises administering to a human or animal in need of treatment an effective amount of an antioxidant lipoic acid derivative and/or pharmaceutically acceptable salts and solvates...
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6576596 |
Substituted 2-benzoyl-cyclohexan-1,3-diones with herbicidal effect
The invention relates to 2-benzoylcyclohexane-1,3-diones of the formula I whereR1, R2 are each hydrogen, nitro, halogen, cyano, thiocyanato, alkyl, haloalkyl, alkoxyalkyl, alkenyl, alkynyl, —OR5, —...
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6570025 |
Sulfur compound and use thereof
This invention provides sulfur-containing (meth)acrylic ester compounds each of which is represented by the following formula (1); wherein R1 and R2 each independently represent a hydrogen atom or...
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6512003 |
Synthetic spiroketal pyranes as potent anti-cancer agents and use
Novel tubulin binding compounds (SPIKETS) having potent tubulin depolymerization activity and inhibitory activity against tubulin polymerization. The compounds are effective agents for inhibiting...
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6472488 |
(Thio) (meth) acrylate monomers, intermediate compounds for the synthesis of these monomers, polymerizable compositions and polymers obtained, and their optical and ophthalmic uses
Polymerizable compositions from novel monomers that correspond to the formula: in which:Z represents H or CH3 and X represents O or S, andY is a 5- to 8-membered heterocycle consisting of hydrogen,...
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6458908 |
Sulfur-containing unsaturated carboxylate compound and its cured products
A sulfur-containing unsaturated carboxylate compound comprising a sulfur-containing substituent and at least two α,β-unsaturated carboxylic acid residues, which are each attached to a secondary o...
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6379590 |
Method for making unsymmetrically substituted fluorenyl compounds for nonlinear optical applications
A new method for producing unsymmetrically substituted fluorenyl compounds, one step of which is the preparation of 2,7-disubstituted fluoren-9-one derivatives via the nucleophilic substitution of...
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6342517 |
Potassium channel activators and their use
Novel thienopyran compounds are disclosed, useful as anti-hypertensive agents and for asthma treatment. One group of the compounds has a heterocyclic ring spiro-connected at the 7-position of the...
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6288071 |
1-ethylene-2-alkylene-1,4-cyclohexadiene pesticides
Pesticidally active cyclohexadienyl derivative compounds of the formula I that are esters, oximes or amides are claimed. These compounds may be used as fungicides, acaricides and insecticides in...
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6022938 |
Compounds with isocyanate groups and masked groups reactive in relation to isocyanates
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6022895 |
Substituted amino compounds and their use as substances having an analgesic effect
Substituted amino compounds of general formula (I) ##STR1## are described, as are a method of preparing them and their use as drugs, especially as analgesics.
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5914351 |
Anti-viral aromatic hydrazones
Compounds of the formula ##STR1## wherein Q is a hydrazone derivative; R1 is hydrogen, halogen, alkyl or alkoxy; R2 is hydrogen, halogen, alkyl, alkoxy, alkenoxy, alkynyloxy, halomethyl,...
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5872121 |
Pesticidal hydrazide derivatives
A compound of the formula ##STR1## wherein R is a) phenyl; phenyl(C1 -C4 alkoxy); phenoxy; or benzyl; the phenyl ring of each substituent being optionally substituted with one or more of halogen,...
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5837725 |
Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors
Bridged bicyclic aromatic compounds are provided having the structure ##STR1## wherein R1, R2, R3, R4, R5 and n are as defined herein. The novel compounds are useful for modulating gene expression...
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5830825 |
3-aryl-tetronic acid derivatives, the production thereof and the use thereof as antiparasitic agents
The present invention relates to new 3-aryl-4-hydroxy-Δ3 -dihydrofuranone derivatives of the formula (I) ##STR1## in which A and B together with the carbon atom to which they are bonded form an ...
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5824484 |
RXR homodimer formation
The invention provides a method of screening a substance for the ability to effect the formation of a retinoid X receptor homodimer comprising combining the substance and a solution containing...
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5767288 |
Photolabile linkers and probes
The invention relates to dithiane adducts of substituted benzoins and substituted benzoins derived therefrom each of which are useful as protecting groups, photolabile linkers, and fluorescent probes.
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5756766 |
Composition for optical materials and use thereof
A composition for optical materials is herein disclosed which comprises the following two components (a) and (b): (a) a component containing at least one of poly isocyanates represented by the...
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5744569 |
One-component and two-component polyurethane coating compositions
In one-component and two-component polyurethane coating compositions comprising at least one reactive component capable of reacting with polyisocyanates, the reactive component is a compound A)...
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5718845 |
Tricyanovinyl substitution process for NLO polymers
Nonlinear optical compounds which contain a heteroaromatic ring and may further comprise a tricyanovinyl group attached to the heteroaromatic ring.
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5693827 |
Treatment of HIV infections and compounds useful therein
A method of inhibiting the growth or replication of viruses of the HIV group is disclosed. Also disclosed are compounds useful in the method and pharmaceutical formulations incorporating such...
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5648354 |
1,2-dithiins having antifungal activity
Novel 1,2-dithiin compounds useful as antifungal or anti-infective agents, as well as methods for their use as such, are described. The 1,2-dithiin compounds are particularly effective in treating...
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5621147 |
Trifluoro-2-(trans-4-substituted cyclohexyl) ethylenes and process for their production
A 1,1,2-trifluoro-2-(trans-4-substituted cyclohexyl)ethylene of the formula (1): R--(A)m --Cy--CF=CF2 (1)wherein R is a C1-10 alkyl group, a halogen atom or a cyano group, provided that in the case...
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5618943 |
Acetylenes disubstituted with a 5 OXO substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity
Compounds of the formula ##STR1## the symbols have the meaning described in the specification have retinoid-like biological activity.
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5583235 |
Preparation of symmetrical and unsymmetrical 3,6-disubstituted-1,2-dithiins having antifungal activity
The present invention provides an improved procedure for the preparation of 3,6-disubstituted-1,2-dithiin derivatives, especially unsymmetrical 1,2-dithiins. In addition, the process offers...
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5574000 |
Cyclohexenone oxime ethers, their preparation and their use as herbicides
Cyclohexenone oxime ethers of the general formula I ##STR1## where R1 is C1 -C6 -alkyl, A is substituted or unsubstituted C4 -alkylene or C4 -alkenylene,X is nitro, cyano, halogen, C1 -C4 -alkyl,...
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5554582 |
Cyclohexenone compounds, their preparation and their use for controlling undesirable plant growth
Cyclohexenone compounds of the formula ##STR1## where R1 is alkyl of 1 to 4 carbon atoms, alkenyl or alkynyl of 3 or 4 carbon atoms, haloalkenyl of 3 or 4 carbon atoms and 1 to 3 halogen...
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5543433 |
Azine-substituted phenylacetic acid derivatives and fungicides containing these
Compounds of the formula I ##STR1## where X is hydrogen, halogen, alkyl, alkoxy, trifluoromethyl, cyano or nitro, Y is an amino, methylamino or dimethylamino group, Z is a group CHCH3, CHOCH3 or...
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5541323 |
Mesogen-containing aromatic anhydride compounds
Anhydride compounds which contain at least one rodlike mesogenic moiety and at least two anhydride groups per molecule, wherein each of said aromatic anhydride groups is linked to the mesogen via...
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5527924 |
Total synthesis of taxol
The present invention provides two basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above...
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5508275 |
Lipid-selective antioxidants and their preparation and use
Lipid-selective antioxidants of the formula I (A)a (L)(X)a, (I),in which A=an antioxidative component, L=a bridging member, X=a lipophilic component a and a'=independently of one another the...
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5502073 |
Heterocyclic pesticidal compounds
Compounds of the formula (I) ##STR1## which contain between 10 and 27 carbon atoms, and wherein m and n are independently selected from 0, 1 and 2; R2a is hydrogen, methyl, or ethyl; R2b is...
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5484872 |
Cyclic sulfide compound, polymerizable compositions for optical products and optical products formed thereof
The present invention provides a cyclic sulfide compound represented by a general formula (I) ##STR1## (where R1 represents --CH2 --CH2 --, --CH2 --CH2 --CH2 --, --CH2 --O--CH2 --, --CH2 --O--, or...
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5463081 |
Arylsulfonylureas, processes for their preparation, and their use as herbicides and growth regulators
The invention relates to novel intermediates for the preparation of a certain group of novel phenylsulfonylurea herbicides, which herbicides are particularly advantageous for use in crop...
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5405968 |
Polyketomethine dyes
Methine dyes with a polyketo group I ##STR1## where A is ##STR2## R1 is a 5- or 6-membered cycloaliphatic radical which contains one or two hetero atoms from the group --NR4 --, --O-- and --S-- and...
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5403938 |
Polythiol compound, and optical material and product produced therefrom
This invention relates-to a polythiol compound and an optical material therefrom. Having a rigid 1,4-dithian ring which increases the refractive index and Abbe's number, the polythiol compound used...
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5296611 |
Propenals substituted with a dithiane ring and processes for the preparation of these propenals
Propenals of formula: ##STR1## in which formula R is H or a C1 -C4 thioalkyl radical, the dithiane ring being at the cis position in relation to the aldehyde function when R is H and at the trans...
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5264455 |
Sulfur-substituted mevinic acid derivatives
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