Matches 151 - 200 out of 383 < 1 2 3 4 5 6 7 8 >
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5250705 Optically active cyclic amine and the process of optical resolution therefor  
The present invention relates to process for the isolation of (-)-(S)-3-methylamino-4-methylenepyrrolidine derivatives of the formula: ##STR1## wherein R is hydrogen or amino-protecting group, from...
5250704 Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines  
A novel process for preparing a stereospecific (S)-3-amino-1-substituted pyrrolidine used as a key intermediate in preparing quinolone and naphthyridone antibacterial agents where the 7-position is...
5233052 Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds  
This invention relates to new diarylpyrrolecarbonitrile and new diarylnitropyrrole compounds. It also relates to the use of said compounds as insecticidal and acaricidal agents and to a method of...
5225568 Process for the preparation of insecticidal, acaricidal and nematicidal 2-aryl-3-substituted-5-(trifluoromethyl)pyrrole compounds  
There is provided a process for the preparation of 2-aryl-3-substituted-5-(trifluoromethyl)pyrrole compounds which are useful as insecticidal, acaricidal and nematicidal agents.
5223530 Arylcycloalkanepolyalkylamine ligands  
Novel arylcycloalkanepolyalkylamines useful as anti-psychotic, anti-ischemia, anti-stroke, anti-dementia and anti-convulsant agents. These arylcycloalkanepolyalkylamines are selective high-affinity...
5223616 Heterocyclic disperse dye compound, their production and their use for dyeing or printing of hydrophobic fibers  
A heterocyclic compound which is useful for dyeing or printing hydrophobic fiber materials and which has the following formula (I), ##STR1## wherein A 1 , A 2 , A 3 and A 4 are each hydrogen,...
5210266 N-substituted mercaptopropanamide derivatives  
Novel N-substituted mercaptopropanamide derivatives of the formula: ##STR1## wherein R 1 is mercapto or a group convertible into mercapto when cleaved within the biobody, W is hydrogen atom, an...
5182348 Arylmethylols, their preparation and their use  
Compounds of the formula (1) ##STR1## wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 have the meanings given in the description, and the other radicals have the following meanings: X,...
5149872 Process for the preparation of oxalyl- and oxamyl-hydrazides  
A new process for preparing oxalyl- and oxamyl-hydrazides which comprises contacting oxamide or diacetyloxamide with the corresponding hydrazine derivative of formula R 1 R 2 N--NHR 3 wherein R...
5145986 Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-substituted-5-(trifluoromethyl)pyrrole compounds from N-(substituted benzyl)-2,2,2-trifluoro-acetimidoyl chloride compounds  
There is provided a process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-substituted-5-(trifluoromethyl)pyrrole compounds via the condensation of an N-(substituted...
5144041 Process for the preparation of 2-aryl-1-substituted-5-(trifluoromethyl) pyrrole compounds useful as insecticidal, acaricidal and nematocidal agents and as intermediates for the manufacture of said agents  
A method for the preparation of insecticidal arylpyrroles, and intermediates for the manufacture of insecticidal arylpyrroles, via a single step 1,3-dipolar cycloaddition process is provided.
5143935 Benzamide derivatives  
A benzamide derivative represented by the formula: ##STR1## having a promoting activity of gastrointestinal tract and pharmacentical composition containing the same.
5130328 N-alkanoylaminomethyl and N-aroylaminomethyl pyrrole insecticidal and acaricidal agents  
This invention relates to N-alkanoylaminomethyl and N-aroylaminomethyl pyrrole compounds. It also relates to the use of said compounds as insecticidal and acaricidal agents and to a method of...
5128485 Synthesis of 2-aryl-5-(trifluoromethyl)pyrroles useful as pesticidal agents and as intermediates for the preparation of said agents  
There is provided a synthesis of 2-aryl-5-(trifluoromethyl)pyrrole compounds via the condensation of a suitable enamine with an α-haloketone.
5120859 Chimeric amino acid analogues  
A chimeric amino acid analogue is provided suitable for incorporating into peptides which compound is represented by Formula 1: ##STR1## where P 1 is preferably an amine protecting agent, and P 2 ...
5112868 Hydroxamate derivatives of selected nonsteroidal antiinflammatory acyl residues having cyclooxygenase and 5-lipoxygenase inhibition  
The present invention is novel selected hydroxamic acid derivatives of acyl residues of selected NSAIDS, i.e. having 5-lipoxygenase and cyclooxygenase inhibiting properties, pharmaceutical...
5099032 Process for the preparation of enantiomerically homogeneous aminopyrrolidinyl naphthyridine and quinolone carboxylic acids.  
A process for the preparation of enantiomerically homogeneous aminopyrrolidinyl naphthyridine carboxylic acids and quinolone carboxylic acids, and for the preparation of intermediates that are...
5075337 Alpha-deuterated 2-alkylaminoacetamide derivatives having reduced toxicity for treatment of CNS disorders  
Deuterated 2-alkylaminoacetamide compounds are described having the alpha carbon of the alkyl side chain of the compounds substituted by one or two deuterium atoms. These compounds have...
5057504 1-heterocyclic bicyclo-octanes  
Pesticidal bicyclo-octanes are of the formula ##STR1## where R is a substituted or unsubstituted aliphatic or aromatic group, R' and R 3 are H or a substituted or unsubstituted aliphatic or...
5053504 Process for benzazepine intermediates  
A process is disclosed for providing benzazepine intermediates of the formulae ##STR1## wherein R 3 , R 4 and Y are as defined herein, which intermediates are useful in a process for the...
5041644 Peptide derivatives of β-chloro-L(Z)-dehydro-glutamic acid  
New peptide derivatives β-chloro-L-(Z)-dehydroglutamic acid are described which display antibacterial activity.
5041545 2-hydroxybenzophenone hydrazides and derivatives thereof  
Hydrazide functionalized 2-hydroxybenzophenone ultraviolet light and heat stabilizers and derivatives are disclosed having the general formula: ##STR1## wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 ,...
5030735 Process for the preparation of insecticidal, acaricidal and nematicidal 2-aryl-5-(trifluoromethyl) pyrrole compounds  
There is provided a process for the preparation of 2-aryl-5-(trifluoromethyl)pyrrole compounds which are useful as insecticidal, acaricidal and nematicidal agents.
4996316 Process for the preparation of tertiary N, N-dimethylamines  
A process for the preparation of tertiary N,N-dimethylamines by the reaction of primary amines, formaldehyde, and hydrogen under pressure and at elevated temperature in the presence of a...
4994615 Process for the preparation of optically active secondary arylamines  
Asymmetric hydrogenation of prochiral N-arylketimines to give optically active secondary amines at a temperature of -20° to 80° C., a hydrogen pressure of 10 5 to 6.10 6 Pa with the addition of...
4992089 Herbicidal compounds, compositions and use  
A compound of formula (I) ##STR1## or a zwitterion derivative thereof; wherein R 1 , R 2 and R 3 are each independently optionally substituted alkyl or R 1 and R 2 together with the nitrogen...
4988711 HMG-CoA reductare-inhibiting N-substituted N-amino-pyrroles  
Inhibiting HMG-CoA reductase, as in treating hyperlipopproteinaemia, lipoproteinaemia and arteriosclerosis, with the new N-substituted N-amino-pyrroles of the formula ##STR1## in which R 1 is an...
4976679 Process for producing a urethane and a carbonic acid ester  
The present invention relates to a process for producing a urethane and a carbonic acid ester which comprises reacting a primary amine, an organic compound containing a hydroxyl group(s), carbon...
4966901 Pyrrole derivatives, their preparation and their use as pharmaceutical active compounds  
Pyrrole derivatives of the general formula I ##STR1## wherein R denotes alkyl which is substituted by --NH 2 or acylamino, R 1 and R 2 independently of one another denote hydrogen or alkyl...
4956475 Preparationof enantiomerically pure 3-protected amino-pyrrolidines  
A process for the preparation of enantiomerically homogeneous aminopyrrolidinyl naphthyridine carboxylic acids and quinolone carboxylic acids, and for the preparation of intermediates that are...
4916152 Pyrrolidine derivatives as antiasthmatics  
The invention relates to novel compounds of the formula: ##STR1## wherein R 1 is hydrogen, lower alkoxycarbonyl, phenylsulfonyl, phenylsulfonyl substituted with 1 to 3 substituent(s) selected from...
4910319 Process for preparing 3-amino-1-benzylpyrrolidines  
A process for preparing a 3-amino-1-benzyl-pyrrolidine of the formula ##STR1## in which R 1 and R 2 each independently is H or alkyl, and Ph is phenyl, comprising reacting a 1-benzyl-Δ 3 ...
4904679 Pyrrolophenylalkanolamines as animal yield promoters  
Pyrrolophenylalkanolamines of the formula ##STR1## R 1 and R 2 represent hydrogen or various radicals, R 3 represents hydrogen, acyl or trialkylsilyl, R 4 represents hydrogen or alkyl, R...
4902709 Novel antihypercholesterolemic compounds  
Novel antihypercholesterolemic compounds of structure (I) or (II), ##STR1## pharmaceutically acceptable salts, thereof and a novel process for preparing compounds of structure I, are disclosed.
4900839 precursors to Quinolone inotropic agents  
A series of novel heterocyclic-substituted 2-(1H)-quinolone compounds have been prepared, including the 3,4-dihydro derivatives thereof, wherein the heterocyclic ring moiety is a pyrrolyl,...
4897397 Aryl-alkynoic, alkenoic or alkanoic compounds and compositions useful as antiallergy and anti-inflammatory agents  
Certain aryl-alkynoic, alkenoic and alkanoic acids and derivatives and their use in treating inflammation, allergy and hyperproliferative skin disease are disclosed.
4859776 (S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carb oxylic acid and method for its preparation  
A process for the preparation of enantiomerically homogeneous aminopyrrolidinyl naphthyridine carboxylic acids and quinolone carboxylic acids, and for the preparation of intermediates that are...
4855292 1-cyclopropyl-6-fluoro-8-alkyl-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives  
Novel 4-oxoquinoline-3-carboxylic acid compounds of the formula: ##STR1## wherein R 2 is 1-pyrrolidinyl which may have 1 to 2 substituents selected from the group consisting of (i) C 1 -C 6 ...
4845090 Nitroxyl compound and diagnostic media based thereon useful for enhancing NMR imaging  
Diagnostic media suitable for NMR diagnoses contain compounds of Formula I ##STR1## wherein is a single bond or a double bond, X is the grouping --(CH 2 ) n -- or, if is a single bond, also...
4840956 Novel disubstituted-7-pyrrolidinoquinoline antibacterial agents  
Disubstituted 7-pyrrolidinoquinoline- and -napthylridine-3-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating...
4839358 Alpha-mercaptomethyl-benzene propanamides, pharmaceutical compositions and use  
Novel α-mercaptomethyl-benzene propanamides of the formula ##STR1## wherein R 1 is selected from the group consisting of hydrogen and ##STR2## R 1 ' is selected from the group consisting of...
4833143 Antidepressant amines  
Compounds of formula I ##STR1## in which R 1 is a heterocyclic ring containing one or more heteroatoms selected from N, O and S; in which R 2 is H, a straight or branched chain alkyl group...
4831132 Ortho-mono-substituted amino)phenylimines  
Novel ortho-(mono-substituted amino)phenylimines being intermediates to psychotropic drugs and other drugs are economically and industrially prepared by reacting anilines with nitriles in the...
4808582 New cinnamoic compounds, the process for preparing same and the use thereof in therapeutics  
Compounds of formula: ##STR1## wherein: Ar is an aromatic group; R and R 1 are H or CH 3 ; A represents a nitrogenized heterocyclic radical; B is OH or forms with the adjacent CO group, either an...
4798901 Novel pyrrole derivatives  
Novel pyrrole derivatives of the formula ##STR1## wherein one of R 2 and R 3 is ##STR2## and the other of R 2 and R 3 as well as R 4 and R 5 are individually selected from the group...
4785119 3-aminopyrrolidine compound and process for preparation thereof  
Disclosed is a novel compound of 3-aminopyrrolidine having the formula (I): ##STR1## in which R 1 is hydrogen, an alkyl, an aralkyl or an aryl.
4774331 Process for ortho-cyanation of phenols or phenylamines  
A process for ortho-cyanation of phenols or phenylamines which comprises reacting a phenyl compound having hydroxy or optionally substituted amino or cyclic amino, of which ortho position is...
4766110 Novel complex amido and imido derivatives of carboxyalkyl peptides  
Novel inhibitors of angiotensin converting enzyme are disclosed which have the general formula ##STR1## wherein R 1 and/or R 3 form complex amides and imides thereof, R 4 and R 5 form with...
4746756 Photoconductive imaging members with novel fluorinated squaraine compounds  
Disclosed are fluorinated squaraine compounds of the following formula: ##STR1## wherein R 1 , R 2 and R 3 are independently selected from the group consisting of alkyl, aryl, and heterocyclic...
4666502 Herbicidal N-thienyl-chloroacetamides  
The invention provides 5-membered heteroaromatic compounds of formula I ArN(Y)COCH 2 Cl I wherein Ar is a 5-membered heteroaromatic group comprising 1...
Matches 151 - 200 out of 383 < 1 2 3 4 5 6 7 8 >