Matches 1 - 50 out of 110 1 2 3 >


Match Document Document Title
8772329 Compounds from mycelium of Antrodia cinnamomea and use thereof  
The present invention relates to compounds from mycelium of Antrodia cinnamomea. The present invention also relates to a composition and a method for treating or prophylaxis of hepatitis C virus...
7850955 Gelling agent  
Gelling agents which contain a specific N-acylamino acid monoamide monoalkyl ester have a melting temperature of about 100° C., are capable of solidifying a wide variety of oily base materials...
7550453 2-alkoxy-3,4,5-trihydroxy-alkylamides, preparation thereof, compositions containing them and use thereof  
The invention relates particularly to 2-alkoxy-3,4,5-trihydroxy-alkylamides, preparation thereof, compositions containing them and use thereof as a medicament, particularly as anti-cancer agents.
7528264 Hydride reduction process for preparing quinolone intermediates  
Hydride process for making acyclic diol intermediates from cyclic intermediates, useful in antibacterial quinolone synthesis.
7282517 Method of manufacturing glimepiride and the respective intermediate  
A method of manufacturing glimepiride of formula I wherein trans-4-methylcyclohexylamine pivalate of formula VII is reacted, either directly or after conversion to trans-4-methylcyclohexylamine or...
7125442 Lightfast additive having UV-absorbing moiety and ink composition including the same  
A lightfast additive and an ink composition including the same include a benzophenone moiety for lightfastness and a moiety for wettability and the ability to stabilize a colorant, wherein the two...
7022863 Production method of pyrrolidone carboxylic acid and salt thereof  
The present invention provides a production method of pyrrolidone carboxylic acid or a salt thereof, which includes bringing glutamic acid or a salt thereof into contact with high-temperature...
6967107 N-aryl-carbamic acid ester-derived and valeric acid ester-derived cross-linkers and conjugates, and methods for their synthesis and use  
The present invention describes carbamic acid ester-derived and valeric acid ester-derived polyfunctional cross-linker molecules, and methods for their synthesis and use. The inclusion of...
6906198 Antipicornaviral compounds, their preparation and use  
Peptido and peptidomimetic compounds of the formula: wherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C...
6627760 Amorphous compound  
The present invention relates to a novel form of (S)-1-[N2-(1-carboxy-3-phenylpropyl]-L-lysyl]-L-proline known under the generic name lisinopril. Further, the present invention also relates to the...
6403830 Amidino compound and salts thereof useful as nitric oxide synthase inhibitors  
The present invention relates to S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine, or a pharmaceutically acceptable salt thereof.
6365743 Process for the preparation of enantiomerically pure imidazolyl compounds  
The invention relates to a method for the preparation of an enantiomerically pure imidazolyl compound of the general formula wherein:n is 0 or 1;m is 1 or 2;R1 is hydrogen, methyl or ethyl; andC*...
6362215 Composition for laying hens containing calcium L-pidolate  
The invention concerns the use of calcium L-pidolate for obtaining an agent improving the quality of eggshells and a composition capable of being administered to laying hens. Said composition is...
6288240 Preparation of 2-hydroxy-5-oxoproline and analogs thereof  
The compound 2-hydroxy-5-oxoproline and analogs thereof may be used to produce an increase in carbon dioxide fixation, growth, dry weight, nutritional value (proteins and amino acids), nodulation...
6133308 Synthesis of clasto-lactacystin beta-lactone and analogs thereof  
The present invention is directed to an improved synthesis of clasto-lactacystin-β-lactone, and analogs thereof, that proceeds in fewer steps and in much greater overall yield than syntheses...
5869675 Lactacystin derivatives  
Novel lactacystin derivatives other than lactacystin per se, with superior activity for the genesis of neurites and highly selective toxicity and low cytotoxicity as compared with known...
5616727 Process for purifying 1-[N2 -((S)-ethoxycarbonyl)-3-phenylpropyl)-N6 -trifluoroacetyl]-l-lysyl-l-proline (lisinopril (TFA) ethyl ester  
A process for purifying 1-[N2 -((S)-ethoxycarbonyl)-3-phenylpropyl)-N6 -trifluoroacetyl]-1-lysyl-1-proline by extraction and crystallization. The process includes a two step extraction in a two...
5605925 1-aminoacetamidopyrroles and 1-amino acetamido-2-(substituted) pyrroles and related compounds  
There are disclosed 1-aminoacetamidopyrroles and 1-amino-2-(substituted)pyrroles and related compounds of the formula ##STR1## wherein all substituents are defined herein, which are useful as...
5369122 Process for manufacturing a humectant  
In a process for manufacturing a humectant with a chemical structure similar to that of natural moisture regulators, residual molasses from sugar beet molasses are treated and the organic acids...
5364948 Biologically active compounds isolated from aerobic fermentation of Trichoderma viride  
This invention relates to compounds of structural formula (I) isolated from an aerobic fermentation of Trichoderma viride MF5628, ATCC 74084: ##STR1## which are squalene synthase inhibitors and...
5306826 Process for preparation of an optically active amino acid amide  
The present invention relates to a process for the preparation of optically active amino acid amide. L-amino and D-amino acid amides are mixed in the presence of 0.5-4 equivalents of an aldehyde,...
5236946 Amino acid esters of cycloaliphatic alcohols and their use in treating lipemic disorders  
Amino acid esters of cycloaliphatic alcohols of the formula: ##STR1## wherein A is cyclohexyl, cyclohexenyl, cyclopentyl, or cyclopentenyl, substituted with from one to three radicals selected...
5190980 Pyroglutamic acid esters, their synthesis and use in topical products  
The invention relates to esters of pyroglutamic acid, their synthesis and their use in products for topical application to human skin as precursors of pyroglutamic acid.
5134157 Amino acid of cycloaliphatic alcohols, process for their preparation and use as drugs  
Amino acid esters of cycloaliphatic alcohols of the formula: ##STR1## wherein A is cyclohexyl, cyclohexenyl, cyclopentyl and cyclopentenyl, substituted with from one to three radicals which are...
5132433 Process for the preparation of clausenamide and neoclausenamide, and derivatives thereof  
A process for the preparation of compound of the formula ##STR1## in which R1 --represents ##STR2## and R2 --represents hydrogen, fluorine, chlorine or bromine. Comprising cyclizing compounds of...
5110986 Synthesis of N-t-alkyl-1,2-diacylhydrazines  
This application relates to a process for preparing a N-t-alkyl-1,2-diacylhydrazine by reacting a 1,3,4-oxadiazole with a tertiary alkyl cation precursor in the presence of a strong acid catalyst....
5108482 N-phenylpyrrolidines  
The 1-(3,5-bis-trifluoromethylphenyl)-2-thioxopyrrolidine-4-carb oxylic acid derivatives of the formula I below are suitable for protecting crop plants against the phytotoxic action of herbicides...
5103007 Lipids  
Lipid derivatives represented by the formula: ##STR1## wherein R1 stands for an optionally substituted higher alkyl group, R2 stands for an optionally substituted lower alkyl group or an...
5081289 Synthesis and isolation of nopaline and its analogues  
A method of separating nonpaline derivatives from their diastereoisomers is disclosed along with a method of selectively growing strains of the bacterium A. tumefaciens. Also disclosed are novel...
5081245 Carboxylic acid derivatives  
A compound represented by the formula: ##STR1## wherein R represents a hydrogen atom or a lower alkyl group; R1 represents a higher alkyl group which may be substituted; R2 represents a hydrogen...
4966901 Pyrrole derivatives, their preparation and their use as pharmaceutical active compounds  
Pyrrole derivatives of the general formula I ##STR1## wherein R denotes alkyl which is substituted by --NH2 or acylamino, R1 and R2 independently of one another denote hydrogen or alkyl having 1...
4952706 Derivatives of 2-pyrrolidone-5-carboxylic acid and method of obtaining them  
The new, crystalline trihydrates of sodium L- and D-2-pyrrolidone-5-carboxylate. These trihydrates can be obtained by adjusting the concentration and the temperature in an aqueous solution of...
4946968 Method of preparing alkali metal salts of 2-pyrrolidone-5-carboxylic acid  
Alkali metal salts of 2-pyrrolidone-5-carboxylic acid (pyroglutamic acid) are prepared by heating the corresponding alkali metal salt of glutamic acid to a temperature between its melting point...
4933354 2-pyrrolidone-5-carboxylic acid compounds useful for the treatment of mental disorders  
In one embodiment this invention provides novel 2-pyrrolidone-5-carboxylic acid compounds, and pharmaceutically acceptable salts thereof, represented by the formula: ##STR1## where n is an integer...
4921971 Method of preparing alkaline earth metal salts of 2-pyrrolidone-5-carboxylic acid  
Alkaline earth metal salts of 2-pyrrolidone-5-carboxylic acid (pyroglutamic acid) are prepared by heating the corresponding alkaline earth metal salt of glutaminic acid in the solid state to a...
4863952 Method of promoting percutaneous drug absorption with 2-pyrrolidin-2-one 5-carboxylic acids and esters thereof  
A composition for percutaneous drug administration which contains a compound of the general formula ##STR1## wherein R1 is a hydrogen atom or an alkyl group and R2 is a residue of aliphatic...
4847287 Pure enantiomers of 4,5-disubstituted gamma-butyrolactams, and their use as antiamnestic agents  
The invention provides pure enatiomers of 4,5-disubstituted γ-butyrolactams of the general formula ##STR1## By means of the pure enantiomers of 4,5-disubstituted γ-butyrolactams (I), according to...
4820818 Process for the geometric stereoselective dehydration of 3-(9-chloro-5,6-dihydro-11H-11-hydroxy-pyrrolo-(2,1-B)(3)-benzazepin-11- yl)-N,N-dimethyl-1-propanamine  
The muscle relaxant (E)-3-(9-chloro-5,6-dihydro-11H-pyrrolo[2,1-b][3]benzazepin- 11-ylidene-N,N -dimethyl-1-propanamine is prepared by the geometric stereoselective dehydration of the intermediate...
4785109 Certain sulfonyl carbamates or thiocarbamate intermediates  
These is described a process for producing sulfonylureas of the formula ##STR1## wherein G is an unsubstituted or substituted furanyl, thienyl, pyrrolyl, pyridinyl or phenyl radical, X is alkyl,...
4772601 5-Substituted 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinones, pharmaceutical compositions and use  
There are disclosed compounds of the formula ##STR1## where R1 is loweralkoxycarbonyl, --CH2 OH or --CONR3 R4, R3 and R4 being independently hydrogen, loweralkyl or arylloweralkyl; and R2 is --CH2...
4731455 Process for the preparation of gamma-butyrolactams  
A process for the preparation of a C(3)-C(4)-transconfigurated γ-butyrolactam of the formula (I) ##STR1## in which R1 represents hydrogen or alkyl, aryl or aralkyl with in each case up to 10...
4663319 3-(1,3-dithiol-2-ylidene)-2,4-dioxopyrrolidines, -piperidines, and -hexahydroazepines and use thereof against hepatic diseases  
Novel thioketene derivatives of the formula: ##STR1## wherein R1 is hydrogen atom, an alkyl group, a lower alkenyl group, a phenyl group or a group of the formula: --B--Y; Y is a...
4604402 Hydroxy substituted ureido amino and imino acids  
Compounds of the formula ##STR1## are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity and depending upon the definition...
4528392 Aromatic compounds as antiallergic agents  
There are disclosed compounds of the formula ##STR1## wherein X is OR2, SR2, N(R2)2 or halo; W is --CH2 --, ##STR2## Y is --CH2 O--, --OCH2 --, --CH2 S--, --SCH2 --, ##STR3## m is 0-6; n is 0-6; p...
4511576 Antidiabetic pyrrolecarboxylic acids  
Certain pyrrolecarboxylic and pyrroleacetic acid derivatives substituted on the pyrrole ring with thioether groups, acyl groups, phenyl, substituted phenyl, phenoxy, substituted phenoxy, benzyl or...
4399290 Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl)heptanoates  
Optically active tert-alkyl 7-2(oxo-5-carbonyloxypyrrolidinyl)heptanoates and their preparation by reaction of racemic tert-alkyl 7-(2-oxo-5-carboxypyrrolidinyl)heptanoate with an optically active...
4393219 Salt of chlorhexidine  
There is provided the novel salt: chlorhexidine di-2-pyrrolidone-5-carboxylate which has potent antibiotic activity and is easily crystallizable.
4383112 Chiral amino-alcohol complexes  
Chiral Schiff bases according to the general formula: ##STR1## and transition metal complexes thereof, wherein C* is an asymmetric carbon atom, R1 and R2, which may be the same or different are...
4296110 Antihypertensive I-substituted cyclic lactam-2-carboxylic acids  
1-Substituted cyclic lactam-2-carboxylic acids and their derivatives are useful as antihypertensive agents.
4264503 Polymerization process using a sodium carboxylactamate catalyst  
The polymerization of 2-pyrrolidone is achieved in high yield in the presence of a sodium-derived catalyst activator produced by the reaction of carbon dioxide with the sodium lactamate derived...

Matches 1 - 50 out of 110 1 2 3 >