Patents in Class 548/455

Matches 1 - 50 out of 492

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Match	Document	Document Title
1	7615646	Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups This invention relates to the functionalized cyanine dyes and more particularly, to the synthesis of chiral 3-substituted 2,3′-dymethyl-3H-indole and its derivatives as intermediates for...
2	7612099	Vinylogous acid derivatives The invention is concerned with vinylogous acids derivatives of formula (I) wherein A and R 1 to R 6 are as defined in the description and in the claims, as well as physiologically acceptable...
3	7598359	Bis (indolestyryl) compound and high density recording media utilizing the same A bis(indolestyryl) compound. The bis(indolestyryl) compound has formula (I): wherein A and B comprise benzene, naphthalene, or heterocyclic ring containing O, S, or N, R1 and R1′ are H,...
4	7598360	Bisstyryl compound and high density recording media utilizing the same A bisstyryl compound. The bisstyryl compound has formula (I): wherein Z 1 and Z 2 are benzene, naphthalene, or heterocyclic ring, R 1 is H, C 1-5 alkyl, hydroxyl, halogen atoms, or...
5	7585981	Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof The present invention provides an industrial method that allows to produce an indole derivative trimer with high purity in mass, as well as novel indole derivative trimers obtainable by the method,...
6	7582770	Viral polymerase inhibitors An enantiomer, diastereoisomer or tautomer of a compound, represented by formula I: wherein A, B, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , and R 10 are as defined herein, or a...
7	7511155	Reagents and a method for saturation labelling of proteins A matched set of fluorescent dyes is provided, wherein each dye of the set is capable of covalent attachment to a protein and wherein each of the dyes has a molecular structure and a charge that is...
8	7495111	Compounds useful as serotonin inhibitors and 5-HT_1Aagonists and antagonists 3-Amino chroman and 2-amino tetralin derivatives and compositions containing such compounds are disclosed. Such compounds are useful for modulating activity of a 5-HT 1A receptor (agonizing or...
9	7465810	Reactive 1,3′-crosslinked carbocyanine Chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3′-position, their bioconjugates and their uses are described. 1,3′-crosslinked...
10	7446212	Polymethine ethers The invention provides novel compounds useful as intermediates for the production of polymethine compounds containing a desired counter ion with high purity and in high yields. Thus provided are...
11	7417062	Substituted arylamides Substituted benzamide compounds are provided along with methods for the use of those compounds for treating cancer.
12	7402677	Fluorescent through-bond energy transfer cassettes based on xanthine and pyronin derivatives A TBET cassette including at least one xanthine- or pyronin-based compound as a donor or acceptor is disclosed. Also, a method of TBET cassette design in which four criteria may be used is...
13	7388026	Prodrugs of CC-1065 analogs Prodrugs of analogs of the anti-tumor antibiotic CC-1065 having a cleavable protective group such as a piperazino carbamate, a 4-piperidino-piperidino carbamate or a phosphate, in which the...
14	7375129	Bis-indole pyrroles useful as antimicrobials agents Compounds of Formula I, commonly referred to as bis-indole pyrroles, including isolated naturally-occurring compounds, synthetic and semi-synthetic derivatives thereof having antimicrobial...
15	7348425	Inhibitors of HCV replication Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions...
16	7342119	Process for the synthesis of a CPLA₂inhibitor A process for making a substituted indole compound, including the steps of: reacting the compounds in a non-protic polar solvent in the presence of a catalyst to form the intermediate compound ...
17	7259213	Indole resins epoxy resins and resin compositions containing the same This invention relates to epoxy resins containing indole as structural unit, indole resins and resin compositions containing said epoxy resins and indole resins useful for applications such as...
18	7253203	Indoline derivatives This invention relates to substituted indoline derivative compounds which are antagonists of the progesterone receptor, their preparation and pharmaceutical utility, particularly including...
19	7244743	Non-peptidic BRS-3 agonists Selectively BRS-3-agonistic compounds of formula I wherein A 1 , A 2 , A 3 , R 1 , R 2 , R 3 , Ar 1 , Ar 2 , Ar 3 , m and n have the meanings given in the description, and also pharmaceutical...
20	7241897	Process for preparing cyanine dye labeling reagents This invention provides for labeling reagents, labeled targets and processes for preparing labeling reagents. The labeling reagents can take the form of cyanine dyes, xanthene dyes, porphyrin dyes,...
21	7232843	Compositions containing C-substituted diindolylmethane compounds Disclosed are methods and compositions for the treatment of a wide array of cancers and tumors. In illustrative embodiments, diindolylmethanes, C-substituted diindolylmethanes, and analogs thereof...
22	7232906	Substituted pyrrolines as kinase inhibitors The present invention is directed to novel substituted pyrroline compounds useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating...
23	7172907	Cyanine dye labelling reagents with meso-substitution Disclosed are cyanine dyes having meso-substituents in the polymethine chain linking the heterocyclic ring systems. The dyes are of formula (1): in which groups R 3 and R 4 are attached to...
24	7173057	Ketoamides with cyclic P4'S as inhibitors of NS3 protease of hepatitis C virus The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses...
25	7157577	5-sulfonamido-substituted indolinone compounds as protein kinase inhibitors The present invention relates to 5-sulfonamido substituted indolinones that modulate the activity of protein kinases (“PKs”). The compounds of this invention are therefore useful in treating...
26	7153852	Indole compounds, process for producing the same and drugs containing the same as the active ingredient Indole derivatives represented by formula (I) wherein all symbols represent the same as that in specification), production methods thereof, and DP receptor antagonist comprising them as active...
27	7153848	Inhibitors of HCV replication Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions...
28	7148249	Indolinones substituted by heterocycles, the preparation thereof and their use as medicaments The present invention relates to heterocyclically substituted indolinones of general formula wherein R 1 to R 5 and X are defined as in claim 1, the tautomers, the diastereomers, the...
29	7129250	Neuroprotective and anti-proliferative compounds This invention features ring-substituted pyrrolo-β-carboline derivatives and ring-substitution and structural derivatives of 3-(1H-indol-3-yl)-1H-pyrrole-2,5-dione of formulas I–III, which are...
30	7115751	Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof The present invention provides an industrial method that allows to produce an indole derivative trimer with high purity in mass, as well as novel indole derivative trimers obtainable by the method,...
31	7105516	Compounds for the treatment of premature ejaculation The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts or solvates thereof and pharmaceutically acceptable formulations comprising said compounds useful...
32	7094796	Coupling product between tryptamine and an alpha-amino acid, process for its preparation as well as its application in the neurocosmetic field The purpose of the invention concerns a family of pseudodipeptides which are coupling products between tryptamine, an indole-primary amine, and a selection of alpha-amino acids, the said...
33	7091348	Fluorescent dyes, energy transfer couples and methods Fluorescent dyes, fluorescence energy transfer dye couples, multi-color dye sets, can be employed in art-recognized assays and certain novel methods, such as in proximity assays.
34	7087358	Image-formation material and infrared absorber A heat mode-applicable image-formation material having high sensitivity and excellent image-forming property, and a novel infrared absorber which can be suitably used in this material. The present...
35	7084166	Bis-heterocyclic compounds with antitumour and chemosensitising activity Bis-heterocyclic compounds of general formula (I) are described which are useful as antitumour and cheomsensitising agents.
36	7081472	Substituted bis-indole derivatives useful as contrast agents, pharmaceutical compositions containing them and intermediates for producing them Metal-complexable substituted bis-indole derivatives comprising the structure shown in formula (I) hereunder: enantiomers and pharmaceutically acceptable salts thereof and metal complexes thereof,...
37	7074938	Method for the synthesis of soritin compounds Disclosed herein are methods for synthesizing biologically active bis-heterocyclic compounds, e.g. bis-indoles. In particular, methods for making Soritin compounds such as Soritin B,...
38	7071332	Indolinone derivatives as protein kinase/phosphatase inhibitors The present invention relates to certain 2-indolinone compounds which modulate the activity of protein kinases (“PKs”) and phosphatases. The compounds of this invention are therefore useful in...
39	7060843	Electroluminescent devices comprising diketopyrrolopyrroles Electroluminescent device comprising in this order (a) an anode (b) a hole transporting layer (c) a light-emitting layer (d) optionally an electron transporting layer and (e) a cathode and a...
40	7049314	Cyclopentyl indole derivatives The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts or solvates thereof and pharmaceutically acceptable formulations comprising said compounds useful...
41	7045360	Method for analysis of reaction products The present invention provides methods, compounds, and kits useful in the analysis of reaction products and components of reaction mixtures, and in certain embodiments for the rapid and...
42	7034050	Pseudopeptides growth hormone secretagogues The present invention relates to novel growth hormone releasing pseudopeptides capable of stimulating the release of growth hormone from the pituitary and of promoting growth in mammals. The...
43	7022730	Bis-heteroaryl alkanes as therapeutic agents This invention provides compounds which are useful as inhibitors of protein tyrosine phosphatases (PTPases). As inhibitors of PTPases the compounds of the invention are useful for the management,...
44	6995262	Use of acylsulfonamido-substituted polymethine dyes as fluorescene dyes and/or markers The invention relates to a novel polymethine dyes containing at least one acylsulfonamido group of the formula (I) in which n, Y, A and R have the meaning given in the claims, and at least one...
45	6977305	Modified carbocyanine dyes and their conjugates Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described....
46	6939975	Cyanine dyes A compound represented by the following formula (I) or a salt thereof: wherein R 1 and R 2 represent an alkyl group or an aryl group; R 3 to R 6 represent hydrogen atom, an alkyl group, an...
47	6902861	Infrared absorbing compounds and their use in photoimageable elements Infrared absorbing compounds in which the anion is selected from the group consisting of 5-isatinsulfonate, 10-camphorsulfonate, and 4,5-dihydroxy-1,3-benzenedisulfonate are disclosed....
48	6894042	Azabicyclic compounds for the treatment of disease The invention provides compounds of Formula I: wherein Azabicyclo is These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or...
49	6867198	Agents and methods for the treatment of proliferative diseases The present invention provides selective kinase inhibitors of formula (I)
50	6844342	Heterocyclic substituted 2-methyl-benzimidazole antiviral agents The present invention concerns antiviral compounds, their methods of preparation and their compositions, and use in the treatment of viral infections. More particularly, the invention provides...

Matches 1 - 50 out of 492

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