|
Match
|
Document |
Document Title |
|
|
7615572 |
Pyrrole and pyrazole DAAO inhibitors
Methods for increasing D-Serine concentration and reducing concentration of the toxic products of D-Serine oxidation, for enhancing learning, memory and/or cognition, or for treating schizophrenia,...
|
|
|
7601847 |
Preparation and purification of 4-(indazol-3-yl)phenols
The present invention concerns processes for the production and purification of compounds of the formula:
where R 1 -R 10 are as defined in the specification. Preferred processes of the...
|
|
|
7598286 |
[(1H-indazol-3-yl)methyl]phenols and (hydroxyphenyl)(1H-indazol-3-yl)methanones
This invention provides anti-inflammatory agents of formula I, having the structure
wherein A and R 1 -R 10 are as defined in the specification, or a N-oxide thereof or a pharmaceutically...
|
|
|
7592363 |
Indazoles
This invention provides compounds of Formula (I) or (Ia):
that are useful in the treatment or inhibition of LXR mediated diseases.
|
|
|
7589232 |
Alkynyl aryl carboxamides
The present invention is related to alkynyl aryl carboxamides of Formula (I′) and use thereof for the treatment and/or prevention of an inflammatory disorder, obesity and/or metabolic disorders...
|
|
|
7560478 |
Crystal forms of substituted phenylalkanoic acids and process for producing the same
In the case of using 3-[3-amino-4-(indan-2-yloxy)-5-(1-methyl-1H-indazol-5-yl)phe
nyl]propionic acid, methyl 3-[4-(indan-2-yloxy)-3-(1-methyl-1H-indazol-5-yl)-5-nitrophe
nyl]propionate, or methyl...
|
|
|
7544707 |
Bicyclic derivatives as PPAR modulators
The present invention is directed to compounds represented by the following structural formula, Formula (I), and stereoisomers, pharmaceutically acceptable salts, solvates and hydrates thereof,...
|
|
|
7541376 |
1H-indazole compounds
The present invention provides a novel 1H-indazole compound having an excellent JNK inhibitory action. More specifically, it provides a compound represented by the following formula, a salt thereof...
|
|
|
7514465 |
Synthesis of N2-(substituted arylmethyl)-3-(substituted phenyl)indazoles as novel anti-angiogenic agents
Novel compounds of 2-(substituted arylmethyl)-3-(substituted phenyl)-2H-indazoles and 1-(substituted arylmethyl)-3-(substituted phenyl)-1H-indazoles are synthesized, and useful as anti-angiogenic...
|
|
|
7514463 |
Lonidamine analogues and their use in male contraception and cancer treatment
Novel compounds useful for inhibiting spermatogenesis and cancer treatment, and in particular as inhibitors of heat shock proteins and/or elongation factor 1 alpha.
|
|
|
7491741 |
Diaminopropionic acid derivatives
A compound of formula 1a
which is useful for treating reperfusion injury, and salts, prodrugs, and related compounds.
|
|
|
7488747 |
Pyrrole and pyrazole DAAO inhibitors
Methods for increasing D-Serine concentration and reducing concentration of the toxic products of D-Serine oxidation, for enhancing learning, memory and/or cognition, or for treating schizophrenia,...
|
|
|
7485659 |
Anticancer compositions, and methods of making and using the same
Compositions, containing a ruthenium(III) complex and a heterocycle, methods for their manufacture, medicament containing these compositions and a kit. The invention relates to a composition (A),...
|
|
|
7473701 |
Substituted indazoles, compositions containing them, method of production and use
Substituted indazoles, compositions containing them, method of production and use. The present invention relates in particular to novel specific substituted indazoles exhibiting kinase-inhibiting...
|
|
|
7470717 |
Indazole derivatives
The present invention provides a compound represented by Formula (I):
[wherein R 1 represents CONR 1a R 1b (wherein R 1a and R 1b may be the same or different and each represents a hydrogen...
|
|
|
7459564 |
Substituted biaryl compounds as factor XIa inhibitors
The present invention provides compounds of Formula (I):
or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, L, Z, R 3 , and ring B...
|
|
|
7449586 |
Processes for the preparation of CGRP-receptor antagonists and intermediates thereof
The invention relates to novel processes for the preparation of small molecule antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”) and intermediates thereof.
|
|
|
7446118 |
3-amino-1-arylpropyl indoles and aza-substituted indoles and uses thereof
The present invention provides compounds of the formula:
or pharmaceutically acceptable salts, solvates or prodrugs thereof,
wherein p, Ar, R 1 , R 2 , R 3 , R a , R b , R c , R d and R e ...
|
|
|
7439262 |
Substituted 1-alkylamino-1-H-indazoles for the treatment of glaucoma
Substituted 1-alkylamino-1H-indazoles for lowering intraocular pressure and treating glaucoma are disclosed.
|
|
|
7414132 |
Opioid receptor antagonists
A compound of the formula (I); wherein the variables X 1 to X 10 , R 1 to R 7 including R 3′ , E, W, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate,...
|
|
|
5633265 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgetics
Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a...
|
|
|
5612342 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
[(4-heteroaryl-1-piperindyl)alkoxy]-3,4-dihydro-1(2H)-naphthalenones and related compounds and their therapeutic utility
Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a...
|
|
|
5605913 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
1-(arylthioalkyl, arylaminoalkyl or arylmethylenealkyl)-4-(heteroaryl) piperidines and related compounds useful as antipsychotics and analgesics
Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. the compounds are especially useful for treating psychoses by administering to a mammal a...
|