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9000186 Ring-fused heterocyclic derivative  
A ring-fused heterocyclic derivative represented by the following general formula (I) or a pharmaceutically acceptable salt thereof having a T-type calcium channel regulatory effect and useful as...
8993778 Process for manufacture of telmisartan  
A process for preparing telmisartan by reacting 2-n-propyl-4-methyl-6-(1′-methylbenzimidazol-2′-yl)benzimida zole with a compound of formula (IV) wherein Z is a leaving group, to obtain the...
8980920 Antiviral compounds of three linked aryl moieties to treat diseases such as hepatitis C  
The present invention relates to novel Linked Tricyclic Aryl Compounds, compositions comprising at least one Linked Tricyclic Compound, and methods of using Linked Tricyclic Aryl Compounds for...
8969345 Dibenzooxepin derivative  
A dibenzoxepin derivative represented by the following general formula (I) wherein Y is a hydrogen atom and the like, RA is a hydrogen atom and the like, X is the formula (b3) wherein RB is a...
8957222 Process for preparing intermediates of peripherally-selective inhibitors of dopamine-β-hydroxylase involving catalytic asymmetric hydrogenation  
A process for preparing the S or R enantiomer of a compound of formula A, the process comprising subjecting a compound of formula B to asymmetric hydrogenation in the presence of a chiral...
8951831 Binaphthalene derivatives, preparation method thereof and organic electronic device using the same  
The present invention relates to a new binaphthalene derivative, a preparation method thereof, and an organic electronic device using the same. The binaphthalene derivative according to the...
8933095 KAT II inhibitors  
Compounds of Formula I: wherein X, Y, Z, R1, R2, R3, R4 are as defined herein, and pharmaceutically acceptable salts thereof, are described as useful for the treatment of cognitive deficits...
8921369 Inhibitors of HCV NS5A  
Provided herein are compounds, pharmaceutical compositions and combination therapies for inhibition of hepatitis C.
8883800 Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions  
The present invention relates to substituted quinazolines of formula (I): wherein X and Y are defined as in claim 1, the tautomers, stereoisomers, mixtures and salts thereof, which have valuable...
8859599 Androgen receptor modulating compounds, preparation and uses thereof  
The present invention concerns compounds of general formula (I): Method of preparation and uses thereof.
8835646 Organic compounds  
The present invention provides a compound of formula I: Said compound is inhibitor of aldosterone synthase and aromatase, and thus can be employed for the treatment of a disorder or disease...
8785002 High-energy triplet host materials, luminescent layer comprising the same, and organic electroluminescent device comprising the luminescent layer  
The present invention includes high triplet energy compositions of matter, methods of their manufacture, devices incorporating the compositions of matter, and methods of using those compositions...
8729096 Imidazolidine-2,4-dione derivatives as N-formyl peptide receptor 2 modulators  
The present invention relates to novel imidazolidine-2,4-dione derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators...
8710082 Benzimidazole inhibition of biofilm formation  
The various embodiments relate to a compound comprising: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are each independently hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl,...
8703099 Registry method and control system for DEA schedule II-V medicines  
The present invention provides compositions and methods for synthesizing labeled drugs. The present invention further provides methods for preventing or stopping prescription drug abuse for all...
8703964 Bendamustine cyclopolysaccharide compositions  
The present invention is directed to pharmaceutical compositions comprising: (a) bendamustine, (b) a charged cyclopolysaccharide, and (c) a stabilizing agent having a charge opposite to that of...
8697885 Carbazole compound, light-emitting element material, organic semiconductor material, light-emitting element, light emitting device, lighting device, and electronic device  
An object is to provide a novel carbazole compound that can be used for a transport layer, a host material, or a light-emitting material in a light-emitting element. A carbazole compound where...
8674138 Binaphthalene derivatives, preparation method thereof and organic electronic device using the same  
The present invention relates to a new binaphthalene derivative, a preparation method thereof, and an organic electronic device using the same. The binaphthalene derivative according to the...
8633235 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof  
Compounds of Formula (I) or pharmaceutically acceptable salts thereof; wherein R1, R2, R3, and R4 are as defined in the specification as well as salts and pharmaceutical compositions including the...
8623899 Bis-benzimidazole derivatives as hepatitis C virus inhibitors  
Inhibitors of HCV replication of formula I including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein R and R′ have the meaning as defined herein. The present...
8618150 Imidazo[1,2-α]pyridine sulfonamides as TRPM8 modulators  
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows:...
8609862 Use of an adrenal hormone-modifying agent  
The present invention relates to a method of treating a disease or disorder characterised by increased stress hormone levels and/or decreased androgen hormone levels in a subject, comprising...
8603947 (4-haloalkyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides  
A description is given of (4-haloalkyl-3-thiobenzoyl)cyclohexanediones of the formula (I) and of their use as herbicides. In this formula (I), X, Y, R1, R2, R3, and R4 are radicals such as...
8586762 Process for producing fused imidazole compound, reformatsky reagent in stable form, and process for producing the same  
The present invention provides an industrially advantageous process for producing a steroid C17,20 lyase inhibitor represented by the general formula (I):
8546440 Substituted bicyclic imidazole derivatives as gamma secretase modulators  
The present invention is concerned with novel substituted bicyclic imidazole derivatives of Formula (I) wherein R0, R1, R3, R4, X, A1, A2, A3, A4, Y1, Y2 and Y3 have the meaning defined in the...
8541555 Hydrazone-based and oxime-based fluorescent and chromophoric/pro-fluorescent and pro-chromophoric reagents and linkers  
Conjugationally extended hydrazine compositions of the formula (RR2)N(H)n(NH2)n, fluorescent hydrazone compositions of the formula (RR2)NN═C(R1R2), methods of the formation of hydrazones from the...
8486980 Tricyclic compound  
Provided is a tricyclic compound having a PPAR γ agonist activity, which is represented by the general formula (I) wherein Z represents a single bond or the like, Y represents a hydrogen atom,...
RE44354 Amyloid plaque aggregation inhibitors and diagnostic imaging agents  
This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to...
RE44338 Amyloid plaque aggregation inhibitors and diagnostic imaging agents  
This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to...
8476453 Process for the preparation of dimiracetam  
The invention relates to a method of manufacture of dimiracetam (2,5-dioxohexahydro-1 H-pyrrolo[1,2-a]imidazole), characterized in that a 4-oxo-butanoic acid ester is condensed with glycinamide in...
8436032 Bendamustine cyclopolysaccharide compositions  
The present invention is directed to pharmaceutical compositions comprising: (a) bendamustine, (b) a charged cyclopolysaccharide, and (c) a stabilizing agent having a charge opposite to that of...
8431608 Heterocycles as potassium channel modulators  
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More...
8399444 Bicyclic imidazole as DP1 receptor antagonists  
The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, processes for their preparation, pharmaceutical compositions containing these...
8389558 Bendamustine amphiphilic anionic compositions  
The present invention is directed to pharmaceutical compositions comprising bendamustine and one or more amphiphilic anionic compounds and self assembled aggregates, which aggregates exhibit...
8383663 Bendamustine anionic-catioinic cyclopolysaccharide compositions  
The present invention is directed to pharmaceutical compositions including: (a) bendamustine, (b) a first charged cyclopolysaccharide, and (c) a stabilizing agent which is a second charged...
8354542 Heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device  
Objects of the present invention are to provide the following: a novel heterocyclic compound which can be used as a material in which a light-emitting substance of a light-emitting layer in a...
8354434 Cyclourea compounds as calcium channel blockers  
The invention relates to cyclourea compounds of Formula I: or a pharmaceutically acceptable salt or solvate thereof, wherein R1-R3 and Z are defined as set forth in the specification. The...
8329140 Method and system for hydrogen evolution and storage  
A method and system for storing and evolving hydrogen (H2) employ chemical compounds that can be hydrogenated to store hydrogen and dehydrogenated to evolve hydrogen. A catalyst lowers the energy...
8314097 Organic compounds  
The present invention provides a compound of formula I: Said compound is inhibitor of aldosterone synthase and aromatase, and thus can be employed for the treatment of a disorder or disease...
8273769 Phenoxy acetic acid derivatives  
The present invention provides phenoxyacetic acid derivatives of Formula (I) for the treatment of CRTH2 related disorders and disease selected from asthma, atopic dermatitis and inflammatory...
8263615 Bis-heterocyclic imidazolyl compounds  
Heterocyclic compounds of the general formula (I) are provided in which R, R1, R2, R3, R4 and n have the definitions elucidated in more detail in the description, to a process for preparing them...
8242156 Linked dibenzimidazole derivatives  
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus...
8232269 Amide compounds useful in therapy  
A compound of Formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein, R1 and R2 each independently represent H, halogen, CF3, C1-3 alkyl or C1-3 alkoxy;R3 represents C1-6...
8217070 2-substituted-1H-benzimidazole-4-carboxamides are PARP inhibitors  
Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of...
8188132 Linked dibenzimidazole derivatives  
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus...
8168668 Compounds  
The present invention relates to new compounds or salts, solvates or solvated salts thereof, processes for their preparation and to new intermediates used in the preparation thereof,...
8147987 Organic electroluminescent element and compounds for use in the element  
An organic electroluminescent element comprises: a pair of electrodes; and one or more organic compound layers at least one of which is a light-emitting layer, the one or more organic compound...
8143420 Bifunctional and trifunctional nitrone spin trapping compounds and uses thereof  
Methods and compositions for detecting free radicals, the compositions being spin trapping compounds comprising a nitrone having a detecting moiety and optionally having a targeting moiety for...
8138182 Diketohydrazine derivative compounds and drugs containing the compounds as the active ingredient  
The present invention relates to a diketohydrazine derivative of formula (I) and a pharmaceutically acceptable salt thereof (the symbols in the formula have the same meaning as described in the...
8124636 Imidazolidinone derivatives as 11B-HSD1 inhibitors  
Compounds of formula as well as pharmaceutically acceptable salts and esters thereof, wherein A and R1 to R4 have the significance given in claim 1 can be used in the form of pharmaceutical...

Matches 1 - 50 out of 303 1 2 3 4 5 6 7 >