Patents in Class 548/237

Matches 1 - 50 out of 264

1 2 3 4 5 6 >

Match	Document	Document Title
1	7626035	Optically active, heteroaromatic β-hydroxy esters and processes for their preparation from β-keto esters and processes for the preparation of these β-keto esters The present invention relates to new optically active heteroaromatic β-hydroxy esters useful in the synthesis of epothilone derivatives, to certain compounds used to produce these intermediates,...
2	7579478	Process for the purification of substituted benzoxazole compounds The present invention provides processes for the purification of substituted benzoxazole compounds, and in particular 2-(3-fluoro-4-hydroxy-phenyl)-7-vinyl-benzooxazol-5-ol. The processes include...
3	7560570	Inhibitors of fatty acid amide hydrolase Potent inhibitors of fatty acid amide hydrolase (FAAH) are constructed having K i 's below 200 pM and activities 10 2 -10 3 times more potent than the corresponding trifluoromethyl ketones. The...
4	7538228	Oxazoline ligands for asymmetric catalysis A chiral ligand represented by the formula and its enantiomer: wherein A, X, Y and Z are as defined in the specification is provided. Also provided is a process of making the chiral ligands and...
5	7358368	Azlactone compound and method for preparation thereof Compounds represented by formula (II): wherein M is a hydrogen atom, sodium, potassium, or lithium; P is a hydrogen atom, an alkyl group, and the like; and the wavy line indicates a cis form, a...
6	7348436	Compounds useful for the synthesis of (+)-discodermolide and methods thereof Compounds and methods useful for the synthesis of (+)-discodermolide, a naturally occurring microtubule stabilizing agent useful as an anti-cancer agent.
7	7309792	Dimeric small molecule potentiators of apoptosis Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent...
8	7241900	Synthesis of indole thiazole compounds as ligands for the Ah receptor A method of synthesizing aromatic ketone compositions of formula I comprising the step of introducing a double bond into the 5 membered ring of the 4,5-dihydro-1,3-azoles moiety of formula II is...
9	7164026	Polymer-carrying optically active binaphthyl type oxazoline compound A polymer-carrying optically active binaphthyl type oxazoline compound having axial asymmetry, represented by the following general formula (1) (wherein R 1 and R 2 may be the same or...
10	7115758	Vitamin D derivatives with cyclic substructures in the side chains, process and intermediate products for their production, and the use for the production of pharmaceutical agents The invention relates to vitamin D derivatives of general formula I, process for their production, intermediate products of the process as well as the use for the production of pharmaceutical...
11	7081536	Isoxazoline derivatives as P N ligands The invention relates to novel ligands of the phosphanylbenzothiophenyl-dihydroisoxazoline, phosphanyl-dihydrooxazolyl-indole and phosphanyl-dihydrooxazolyl-benzofuran type, especially compounds of...
12	7041831	Diastereoselective synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors Disclosed is a method of preparing a composition comprising a compound represented Structural Formula (I): The method comprises the step of reacting an aldehyde compound R 10 CHO with an...
13	6875882	Synthesis of benzonitriles from substituted benzoic acid There is a significant demand for organic nitriles, based on their versatility in reactions. Compounds prepared from nitriles have properties including superoxide inhibition, ferrielectric liquid...
14	6864270	Iron binding agents Composition, article of manufacture for and method of treating malaria in a human having an infestation of Plasmodium protozoans are described. The method comprises administering a...
15	6762199	Indane derivatives The invention is directed to physiologically active compounds of general formula (I): wherein: R 1 represents aryl, heteroaryl or a group R 3 —L 2 —Ar 1 —L 3 —; R 2 represents hydrogen...
16	6706664	Benzoxazole compounds, process for the preparation thereof and herbicides The present invention relates to a benzoxazole compound represented by the following formula (1): wherein R 1 to R 4 each represents hydrogen atom, C 1-6 alkyl group, C 1-4 alkoxy group, C...
17	6649643	Imidazol-4-ylmehanols and their use as inhibitors of steroid C17-20 lyase Imidazol-4-ylmethanols and their uses for preventing and treating primary tumors, metastasis and recurrence of tumors, various symptoms accompanying tumors, prostatic hypertrophy, virilism,...
18	6645984	Arylisoxazoline derivatives, processes for their preparation and their use as pesticides Compounds of the formula (I), are described in which X is halogen, cyano, nitro, (C 1 -C 4 )-alkyl, (C 1 -C 4 )-alkoxy, (C 1 -C 4 )-alkylthio or (C 1 -C 4 )-alkylsulfinyl; R 1 is halogen, (C 1...
19	6624324	Process for producing optically active hemiesters There is disclosed a process for producing an optically active hemiester of formula (1): wherein R 1 , R 2 and R 5 represent the same meanings as described below, which comprises reacting a...
20	6583292	Method for the esterification of alcohols and compounds useful therefor as potential anticancer agents Described herein is a method for preparing an ester by (a) admixing a compound having the formula I: with a base to form an intermediate, and (b) admixing the intermediate produced in step (a)...
21	6576628	3-aryl-succinamido-hydroxamic acids, methods for producing said acids and medicaments containing the same The invention relates to inhibitors of matrix metalloproteases, more specifically a 3-aryl-succinamido-hydroxamic acid of formula (I) and its salt, ester and derivative thereof, along with...
22	6573286	2-(2,6-disubstituted phenyl)-4-aryl-5-alkyl-1,3-oxazoline compounds Oxazoline compounds having a 2,6-disubstituted-phenyl group in the 2-position, an aryl or heteroaryl group in the 4-position and an alkyl group in the 5-position are effective in controlling...
23	6476233	Transition metal-catalyzed reactions based on chiral amine oxazolinyl ligands and related compounds This invention is to develop novel transition metal catalysts for the practical synthesis of important chiral molecules. The invention emphasizes asymmetric catalysis based on chiral amine...
24	6476232	4-(2-amino-1-hydroxyethyl)oxazoline derivative and method for producing same A 4-(2-amino-1-hydroxyethyl)oxazoline derivative of the formula [XIII] and a method for producing the same, in which R 4 is an optionally substituted alkyl, an optionally substituted aryl, an...
25	6472534	Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors Methods for the preparation of chemical intermediates in the synthesis of HIV-protease inhibitors related to and including nelfinavir mesylate are disclosed. The method of this invention comprises...
26	6472533	Ligands for chiral catalysis Novel phosphine oxazoline ligands of formula (I) wherein m is 1, 2, 3 or 4; n, p, q, r are independently zero or 1 provided that at least one of n, p, q and r is 1; X is O, S, Se, CH 2 , NH; Y...
27	6414000	Substituted diphenyl oxazolin derivatives with insecticidal effect The present invention relates to novel oxazoline derivatives of the formula (I) in which the radicals A, B, Q and R are each as defined in the description to processes for their preparation and...
28	6410562	Hypoglycemic imidazoline compounds This invention relates to certain novel imidazoline compounds and analogues thereof, to their use for the treatment of diabetes, diabetic complications, metabolic disorders, or related diseases...
29	6410741	Optically active bisoxazoline compounds, production and use thereof An optically active bisoxazoline compound of the formula [I]: wherein R 1 represents alkyl group, cycloalkyl group, aralkyl group, phenyl group which may be substituted or alkoxy group and two...
30	6380213	Compounds useful as neuro-protective agents This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
31	6316494	cis3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes The present invention relates to therapeutically active compounds of formula I ##STR1## a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel...
32	6265587	Intermediary compounds for the hemisynthesis of taxanes and preparation processes therefor The present invention relates to new intermediates for the semisynthesis of taxanes and their preparation processes. It relates to derivatives of oxazolidines or oxazolidinones, as well as to new...
33	6252085	Production of amide derivatives and intermediates therefor A method for producing an amide derivative of the formula [XV] ##STR1## wherein each-symbol is as defined in the specification, and an enantiomer thereof, a novel intermediate useful for producing...
34	6231786	Fluorinated azoles, and their use in liquid-crystalline mixtures In the fluorinated azoles of the formula (I) R 1 (--A 1 ) a --T--(A 2 --) b (M--A 3 --) c R 2 (I) the symbols and indices have -the following meanings: T is undirected and is ...
35	6228868	Oxazoline antiproliferative agents Compounds having Formula I ##STR1## are useful for treating cancer. Also disclosed are pharmaceutical compositions comprising compounds of Formula I, and methods of treating cancer in a mammal.
36	6211214	Biphenyl ether oxazolines and their use as pest-control agents The present invention relates to novel biphenyl ether-oxazolines of the formula (I) ##STR1## in which X, Y, Z, R 1 , R 2 , A, m and n have the meaning given in the description, to processes...
37	6207693	Benzamide derivatives having a vasopressin antagonistic activity This invention relates to new benzamide derivatives having a vasopressin antagonistic activity, etc. and represented by general formula (I): ##STR1## wherein R 1 is aryl optionally substituted...
38	6172093	Substituted biphenyloxazolines New pesticidal substituted biphenytoxazolines of the formula (I) ##STR1## in which A, B, X, m and n have the meanings stated in the description, and new intermediates therefor.
39	6165944	4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides 4-(3-Heterocyclyl-1-benzoyl)pyrazoles of the formula I ##STR1## where: R 1 and R 3 are each hydrogen, nitro, halogen, cyano, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio,...
40	6153759	Heterocyclic benzoyl intermediates for herbicidal compounds Heterocyclic substituted benzoyl derivatives of the formula ##STR1## where Z is a 5-membered or 6-membered heterocyclic, saturated or unsaturated radical containing one to three hetero atoms...
41	6147220	Process to 5-methyleneoxazolines This invention provides a process for the preparation of a 5-methylene-1,3-oxazoline from an alkyl ketone by reacting the alkyl ketone with an acetylating agent and an acid catalyst in an...
42	6107319	Oxazoline arthropodicides Compounds of Formula I, and their agriculturally-suitable salts, are disclosed which are useful as arthropodicides ##STR1## wherein R 1 -R 5 and n are as defined in the disclosure. Also disclosed...
43	6063932	Process and intermediates for the preparation of oxazoline derivatives Arthropodicidal oxazoline derivatives and processes and intermediates for the preparation thereof are disclosed. The intermediates are racemic or enantiomerically enriched compounds having formula...
44	6051589	Diphenyloxazoline derivatives The invention relates to novel diphenyloxazoline derivatives of the formula (I) ##STR1## in which a) A represents tri- to pentasubstituted phenyl and B represents substituted phenyl or b) A...
45	6031095	Intermediates in the preparation of substituted alkenoic acids This invention relates to a highly selective process for preparation of E-ω-phenyl-ω-(3-pyridyl)-ω-alkenoic acid derivatives bearing a carbamoyl substituted oxazolyl or oxazolinyl group on the...
46	6028089	Phenylthio-oxazoline compounds and their use as pesticides The invention relates to new phenylthio-oxazoline derivatives of the formula (I) ##STR1## in which A represents optionally substituted phenyl; B represents optionally substituted phenyl; D...
47	5998575	Compatibilizing agent and method of producing the same A polymer alloy is obtained by adding a hydrophobic compound (1) having a hydrophobic main chain and a functional group containing an active hydrogen atom and a bisoxazoline compound (2) shown by...
48	5994556	Bis(ortho-diarylphosphinophenyl)-tetrahydro-bi(1,3-oxazole) and a preparation method thereof The present invention relates to optically pure bis(o-diarylphosphinophenyl)-tetrahydro-bi(1,3-oxazole) compounds represented by the formula (I) and a preparation method thereof....
49	5994390	Trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes The present invention relates to therapeutically active compounds of formula I ##STR1## a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel...
50	5990140	Substituted oxazolines of the formula (I) The invention relates to novel substituted oxazolines of the formula (I) ##STR1## in which A, B, D, E and G have the meaning given in the description, to a number of processes for their...

Matches 1 - 50 out of 264

1 2 3 4 5 6 >