Matches 151 - 200 out of 319 < 1 2 3 4 5 6 7 >
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5286881 Process for producing benzodifuranone compounds useful for dyeing or printing hydrophobic fiber materials  
A benzodifuranone compounds of the formula, ##STR1## wherein R 1 and R 2 are each independently a naphthyl group or an unsubstituted or substituted phenyl group, which is useful for dyeing or...
5262430 Substituted 2-imidazolines and use thereof  
The invention relates to novel substituted 2-imidazolines (I) having a lowering effect on blood glucose in mammals, to their preparation, to pharmaceutical compostions containing them and to their...
5258401 Cholesterol lowering compounds  
Disclosed herein are compounds of structural formula (I) ##STR1## which are useful as cholesterol lowering agents. These compounds are also useful as inhibitors of squalene synthase, inhibitors of...
5258357 Carboxamides, their preparation and their use as herbicides  
Carboxamides of the formulae Ia to Ic ##STR1## where X is oxygen or sulfur; R 1 is hydrogen or substituted or unsubstituted cycloalkyl or alkyl; R 2 is hydroxy, alkoxy, cyanoalkyl,...
5246956 N-imidazolyl derivatives of substituted alkoxyimino tetrahydronaphthalenes and chromans having antithromboxane A.sub.2 activity  
The invention provides new imidazole containing alkoxyimino derivatives of tetrahydronaphthalene and chroman of general formula (I) ##STR1## wherein Z is --CH 2 --or--O--; m is an integer of 1...
5245039 Process for preparation of enantiomerically pure polysubstituted 1,4-dihydropyridines  
A process for the optical resolution of racemic 1,4-dihydropyridines, containing isothioureido groups. Salification of racemic isothioureas with optically active acids produces diasteroisomeric...
5242939 Anilide derivatives with angiotensin II antagonist properties  
This invention relates to anilide derivatives of Formula I ##STR1## which antagonize the binding of angiotensin II to its receptors. The compounds are useful in the treatment of hypertension, heart...
5235058 3(5)-hydrazinopyrazole compounds  
There is disclosed a 3(5)-hydrazinopyrazole compound represented by the following formula (I): ##STR1## wherein R 1 represents a hydrogen atom, an alkyl group, an aryl group, a heterocyclic group,...
5190960 Medicinal oxazolopyridine compounds  
Compounds of general formula (I): ##STR1## in which: R 1 and R 2 each represent a hydrogen atom or, with the nitrogen and oxygen which bear them, form an --O--CO--N link, W represents a...
5190573 Cyclohexenone oxime ethers, their preparation and their use as herbicides  
Cyclohexenone oxime ethers ##STR1## where R 1 is alkyl; A is substituted or unsubstituted alkylene or alkenylene, where methylene is replaced by an oxygen atom, a sulfur atom, a sulfoxyl group,...
5179111 Imidazole derivatives  
Imidazole derivatives of general Formula I ##STR1## wherein R 1 means hydrogen, an optionally substituted C 1 -10 hydrocarbon or hetaryl residue, or a cyclic ether residue, R 2 means hydrogen,...
5175182 Acryloyl substituted pyrrole derivatives  
The invention relates to acryloyl substituted pyrrole derivatives of formula (I) ##STR1## wherein n is an integer of 1 to 5; each of R 1 and R 2 , which may be the same or different, is...
5173502 Substituted trifluoropropan-1-yl-imidazole alpha 2-receptor anagonists  
A compound selected from those of formula (I): ##STR1## in which R represents straight-chain or branched lower (C 1 -C 6 ) alkyl, (C 3 -C 8 ) cycloalkyl, optionally substituted phenyl, pyridyl or...
5171859 Certain 2-aminomethyl-3-phenyl-pyridine intermediates for certain 8-phenyl-imidazo[1,5-a]pyridines  
This invention relates to novel substituted imidazo[1,5-a]pyridines, most especially novel 8-phenylimidazo[1,5-a]pyridines. It also relates to novel intermediates and to a novel process for the...
5156670 Cyclic alkylidene substituted pyridine herbicides  
Fully substituted pyridines having a cyclic alkylidene substituent, useful as herbicides, compositions and methods of use thereof.
5149817 Teirahydropyridine derivatives  
The present invention relates to tetrahydropyridine derivatives which have high affinity and specificity to σ receptors, whereby these compounds are thought to be effective for treatment of some...
5142056 Retroviral protease inhibiting compounds  
A retroviral protease inhibiting compound of the formula A--X--B or a pharmaceutically acceptable salt, prodrug or ester thereof, wherein X is a linking group; A is (1) substituted amino, ...
5138070 Pentamethine dyestuffs and derivatives  
Dyestuffs of the formula ##STR1## and their base derivatives, in which the radicals have the meaning given in the description, are outstandingly suitable for laser transfer printing or as optical...
5135825 Method for producing ambient temperature molten salt consisting of certain pyridinium and imidazolium halides and an aluminum trihalide  
There is disclosed a method for producing an ambient temperature molten salt comprising at least one of 1,3-dialkylimidazolium halide, 1,2,3-trialkylimidazolium halide and N-alkylpyridinium halide,...
5126338 Fungicides which are N-pyridyl-cyclopropane carboxamides or derivatives thereof  
Compounds of having the general formula (I): ##STR1## and stereoisomers thereof, wherein R 1 is hydrogen, halogen, C 1 -4 alkoxy, C 1 -4 alkyl, C 2 -4 alkenyl, C 2 -4 alkynyl, C 1 -4 haloalkyl, C...
5122529 Pyridyl cyclopropane carboxamidine fungicides  
A compound of general formula (II): ##STR1## and stereoisomers thereof, wherein R 1 is hydrogen, halogen, C 1 -4 alkoxy C 1 -4 alkyl, C 2 -4 alkenyl, C 2 -4 alkynyl, C 1 -4 haloalkyl, C 1 -4...
5118696 5-Acyl-2-(1H)-pyridinones useful for treating cardiac failure  
Novel 5-acyl-2-(1H)pyrdinones and their use as cardiotonic agents. Typical of the compounds is 5-acetyl-1,2-dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile which is prepared by condensing anionic...
5098917 Substituted imidazolylmethyloxiranes and substituted imidazolypropenes their preparation and fungicides containing them  
Substituted imidazolylmethyloxiranes and substituted imidazolylpropenes of the general formula I ##STR1## wherein R 1 and R 2 are alkyl, cycloalkyl, cycloalkenyl, tetrahydropyranyl, norbornyl,...
5079247 N.sup.1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents  
N 1 substituted benz [cd] indol -2(1H)-imines useful as inhibitors of Thromboxane synthetase enzyme, hypertension and arrhythmia are described.
5075301 Furan derivatives useful for the treatment of gastro-intestinal disorders  
A furan derivative and a pharmaceutically acceptable salt thereof having gastrointestinal enterokinetic activity which is expected to be used in a broad spectrum of diseases associated with...
5075324 Aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical composition containing them  
1,4-dihydropyridines of formula I ##STR1## wherein X is --CO 2 R 1 , cyano, nitro, --COCH 3 ; each of R and R 1 , which are the same or different, is a primary, secondary or tertiary, saturated...
5073671 1-(benzyl or pyridylmethyl)-4 or 5-aminomethyl-pyrrolidin-2-ones  
Compounds of the formula ##STR1## wherein R 1 is hydrogen or alkyl of 1 to 4 carbon atoms; R 2 is 2-, 3- or 4-pyridyl, phenyl or mono- or di-substituted phenyl, where the substituents are each...
5064842 1,4-dihydropyridines  
The invention concerns compounds of formula ##STR1## or salts thereof; wherein: α and β together represent a bond and additionally when B is an electron withdrawing group α can also represent...
5063237 1,4-dihydro-2-(4-[benzimidazol-l-yl]phenyl)-pyridines as platelet activating factor antagonists  
Platelet activating factor antagonists of formula (I): ##STR1## wherein R is phenyl or phenyl substituted by one or more substituents selected from nitro, halo, C 1 -C 4 alkyl, C 1 -C 4 alkoxy,...
5047417 Butenoic or propenoic acid derivatives  
A butenoic or propenoic acid derivative having the following formula in which G is an aryl or a heterocyclic ring, R11 and R12 are hydrogen or an alkyl, X is sulfur or oxygen, R2 and R3 are...
5037824 N-containing heterocyclic compounds, compositions and use  
The invention relates to cardioprotective compounds of the formula: ##STR1## wherein R 1 , R 2 R 3 and R 4 are moieties as described in the specification.
5032590 Substituted hydroxylamines  
Substituted hydroxylamines of the formula ##STR1## in which R 1 stands for an aromatic or heterocyclic radical, are especially useful in the treatment of hyperlipoproteinaemia, lipoproteinaemia...
5026712 Novel imidazo[1,5-a]pyridines, useful as cardiovascular and CNS agents  
This invention relates to novel substituted imidazo-[1,5-a]pyridines, most especially novel 8-phenylimidazo-[1,5-a]pyridines. It also relates to novel intermediates and to a novel process for the...
5021431 Imidazolyl alkyl guanidine derivatives, processes for their preparation and pharmaceutical preparations containing these compounds  
New imidazolylalkyl-guanidine derivatives are described, which by virtue of their agonistic action on histamine-H 2 receptors and in part also due to their additional H 1 -antagonistic receptor...
5006523 Antiarrhythmic agents: aryl cyanoguanidine potassium channel blockers  
Novel compounds of the formula ##STR1## and tautomers thereof are disclosed. These compounds possess potassium channel blocking activity and, as such, are useful as antiarrhythmic agents.
4999364 Azole derivatives  
Azole derivatives of the formulas R 1 --CR 2 R 3 --CHR 4 --CR 5 R 6 --R 7 are described; wherein R 1 is a heterocyclyl radicla selected from 1,2,4-triazolyl, optionally-substituted...
4983617 Stable crystal form of 1,4-dihydro-2-(imidazolyl-1-ylmethyl)-6-methyl-4-(3-nitrophenyl)pyridine -3,5-dicarboxylic acid 3-ethyl 5-methyl diester, hydrochloride  
The invention concerns a new stable crystal form of anhydrous, crystalline 1,4-dihydro-2-(imidazol-1-ylmethyl)-6-methyl-4-(3-nitropheny l)pyridine)-3, 5-dicarboxylic acid 3-ethyl 5-methyl diester...
4980478 Process for producing substituted vinyl pyridine derivatives  
An improved process for producing a substituted vinyl pyridine compound of the general formula: ##STR1## wherein R 1 is pyridyl group; R 2 is an optionally substituted aromatic or heterocyclic...
4978761 5-hydroxy-2-substituted-2,4,6,7-tetramethyl-2,3-dihydrobenzofurans  
The present invention relates to a compound of the formula: ##STR1## wherein R 1 is hydrogen or a lower alkyl; R 2 is methyl which is substituted by a carboxy, alkoxycarbonyl, cyano, halogen,...
4978672 Alpha-heterocyclc substituted tolunitriles  
The invention is concerned with aromatase inhibiting compounds of formula I ##STR1## wherein R and Ro represent hydrogen or lower alkyl; or R and Ro located on adjacent carbon atoms and together...
4966908 Isonicotinic acid amides for protecting plants against disease  
Novel substituted isonicotinic acid amides and isonicotinic acid hydrazides of the general formula ##STR1## in which Hal, each independently of the other, is fluorine, chlorine, bromine or iodine,...
4962117 Heterazole dialkanoic acids  
Compounds having the formula: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, antiallergic, anti-inflammatory, and...
4952587 Physiologically active 1,2,4,-oxa- and thiadiazoles  
The present invention provides a compound of formula I or a salt or prodrug thereof: ##STR1## wherein the dotted circle represents one or two double bonds in any position in the 5-membered ring; ...
4950667 Pyridinyl acetamide compounds useful in treating ulcers  
There are provided acetamide compounds represented by the following formula; ##STR1## wherein R 1 and R 2 each independently represents a hydrogen atom, a C 1 to C 6 straight- or branched-chain...
4946861 1,3-dithian-2-ylidenes, their oxides, pharmaceutical compositions, and methods of use thereof  
The invention relates to the use of ketenethioacetals of the formula ##STR1## in which R 1 represents aryl or heteroaryl, R 2 represents hydrogen, an optionally substituted hydrocarbon radical,...
4940717 Fungicidal imidazolylmethyloxiranes  
Imidazolylmethyloxiranes of the general formula I ##STR1## where R is phenyl, pyridyl, tetrahydropyranyl, norbornyl, C 3 -C 12 -cycloalkyl or C 5 -C 8 -cycloalkenyl, these radicals being...
4921955 Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives  
The invention relates to a process for the preparation of 1,5-disubstituted imidazoles of the formula ##STR1## by alkylation of an N-cyanoformamidine of the formula II X--NH--CHN--CH ...
4912119 Imidazolylguanidine derivatives and compositions containing these compounds  
New imidazolyl guanidine derivatives corresponding to the following general formula ##STR1## are described. These compounds may be used in cardiac diseases, certain forms of hypertension and in...
4900750 1.4-Dihydropyridines  
This invention concerns compounds of formula ##STR1## or salts thereof, wherein: Ar is an optionally substituted aryl radical; R represents hydrogen or an optionally substituted alkyl, aralkyl,...
4895956 3-aroyl-6,7-dihydro-5H-pyrrolo(1,2-c)imidazole-7-carboxylic acid derivatives  
A novel 3-aroyl-6,7-dihydro-5H-pyrrolo[1,2-c]imidazole-7-carboxylic acid derivative which is useful as a medicine having excellent analgesic and anti-inflammatory actions with remarkably less...
Matches 151 - 200 out of 319 < 1 2 3 4 5 6 7 >