|
Match
|
Document |
Document Title |
|
|
7615503 |
Stabilized body care products, household products, textiles and fabrics
Disclosed are stabilized body care products, household products, textiles and fabrics which comprise certain sterically hindered amine salt compounds. Dyed products and articles are effectively...
|
|
|
7589035 |
Stabilized body care products, household products, textiles and fabrics
Disclosed are stabilized body care products, household products, textiles and fabrics which comprise certain sterically hindered amine salt compounds. Dyed products and articles are effectively...
|
|
|
7572869 |
N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, their corresponding n-oxides and controlled radical polymerization therewith
The present invention relates to selected 1-alkoxy-2,2,6,6 tetramethyl piperidine, 1-alkoxy-2,2 diethyl-6,6 dimethyl piperidine and 1-alkoxy-2,6 diethyl-2,3,6 dimethyl piperidine derivatives which...
|
|
|
7550599 |
Water compatible sterically hindered alkoxyamines and hydroxy substituted alkoxyamines
Sterically hindered alkoxyamine and hydroxy substituted alkoxyamine stabilizer compounds are made water compatible via certain backbones with affinity towards water. The sterically hindered amines...
|
|
|
7531555 |
Compositions and methods for selective inhibition of nicotine acetylcholine receptors
The present invention concerns methods for treating or preventing neurological disorders characterized by dysfunction of nicotinic acetylcholine receptors by administering...
|
|
|
7501439 |
Tartrate salt of isofagomine and methods of use
A novel tartaric acid salt of Isofagomine (Isofagomine tartrate) that can be used for the treatment of Gaucher disease is provided. The invention also provides a crystalline form of isofagomine...
|
|
|
7199245 |
4-imino-n-alkoxy or oxy-polyalkyl-piperidine compounds and their use as polymerization regulators
The present invention relates to selected 4-imino-N-alkoxy-polyalkyl-peperidine compounds preparation, a polymerizable composition comprising a) at least one ethylenically unsaturated monomer and...
|
|
|
7196099 |
Compounds and compositions as cathepsin inhibitors
The present invention relates to novel cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.
|
|
|
7144897 |
Hydroxy alkyl amines
Disclosed are compounds of formula X,
which are useful in treating Alzheimer's disease and other similar diseases. Pharmaceutical compositions comprising compounds of formula X and methods of...
|
|
|
7129238 |
Mandelic acid derivatives
The invention is concerned with novel mandelic acid derivatives of formula (I)
wherein R 1 to R 10 , X and Y are as defined in the description and in the claims, as well as pharmaceutically...
|
|
|
7129228 |
Heterocyclic analgesic compounds and methods of use thereof
One aspect of the present invention relates to novel heterocyclic compounds. A second aspect of the present invention relates to the use of the novel heterocyclic compounds as ligands for various...
|
|
|
7122551 |
Metalloproteinase inhibitor compounds
Compounds of the formula I
useful as metalloproteinase inhibitors, especially as inhibitors of MMP 13.
|
|
|
7109217 |
Phenylcarboxamide beta-secretase inhibitors for the treatment of Alzheimer's disease
Disclosed are compounds of formula (I)
which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is...
|
|
|
7091355 |
Chiral scaffolds and their preparation
A crystalline salt according to formula (1): or the opposite enantiomer thereof, wherein X + is a cation. Such salts are useful in preparing chiral scaffolds, in particular of formulae (a)–(d)
|
|
|
7087759 |
Melanocortin receptor ligands
Disclosed are MC-3/MC-4 receptor ligands, the ligands having the following formula:
wherein A is a conformationally restricted ring system selected from the group consisting of:
a)...
|
|
|
7074803 |
Opioid formulations
The present invention provides high-concentration formulations of opioids such as fentanyl or fentanyl congeners. The formulation of the invention comprises fentanyl or a fentanyl congener in...
|
|
|
7001905 |
Substituted diarylamines as MEK inhibitors
Diarylamines, such as 5-amide substituted diarylamines of formula (I) or formula (II) wherein A is hydroxy, C 1-6 alkoxy, or NR 6 OR 7 ; X is OR 12 , NR 13 R 12 , or NR 14 ; inhibitors of MEK and...
|
|
|
6924251 |
Substituted benzoylcyclohexandiones
The invention relates to novel substituted benzoylcyclohexanediones of the general formula (I),
in which
m, n, A, R 1 , R 2 , R 3 , R 4 and Z are each as defined in the description,
and...
|
|
|
6875888 |
Method for the production of esters of unsaturated carboxylic acids
In a process for preparing an ester of an unsaturated carboxylic acid by reacting an ester of the unsaturated carboxylic acid and a C 1 -C 4 -alkanol with an alcohol R 3 OH, where R 3 is a C 4 -C...
|
|
|
6872832 |
Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith
Hindered amines substituted on the N-atom with an —O-E-OH moiety are particularly effective in stabilizing polyolefin and automotive coating compositions against the deleterious effects of...
|
|
|
6852735 |
Siastatin B derivatives having a glycosidase inhibitory activity and processes for producing the same
A compound of the formula (I):
and a compound of the formula (V):
as well as a compound of the formula (X):
which are each a novel siastatin B derivative having a potent inhibitory...
|
|
|
6790845 |
Fused heterocyclic inhibitors of factor Xa
This invention relates generally to a novel class of fused heterocyclic compounds of the Formula (I) or Formula (II): or pharmaceutically acceptable salt forms thereof, which are inhibitors of...
|
|
|
6759430 |
Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress
The present invention relates to chemical compounds comprising a nitric oxide (NO) donor and a superoxide ion (O 2 − ) scavenger, their preparation and their use in the treatment of conditions...
|
|
|
6727300 |
Polymeric articles containing hindered amine light stabilizers based on multi-functional carbonyl compounds
Polymeric articles containing at least one polymeric material and a sufficient amount of at least one novel hindered amine light stabilizers to inhibit at least one of photo- or thermal...
|
|
|
6713492 |
N-acyloxylated cycloalkyl compounds, composition containing the same and methods of use therefor
Drugs or reagents containing as the active ingredient N-acyloxylated cycloalkyl compounds represented by general formula (I): wherein A is optionally substituted C 4 or C 5 cycloalkyl which...
|
|
|
6664411 |
Heterocyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their...
|
|
|
6653480 |
Process for the preparation of 1,5-dideoxy-1, 5-imino hexitols from oximes or imines
A process for the preparation of 1,5-dideoxy-1,5-imino hexitols of a hexose sugars from novel hydroxyl protected oxime intermediates. The process includes formation of a lactam which is reduced to...
|
|
|
6617454 |
Process for the preparation of amine oxides
The present invention provides a process for the preparation of amine oxide by reacting a tertiary or a secondary amine with hydrogen peroxide as an oxidant in the presence of a recyclable...
|
|
|
6610709 |
2-n-substituted or unsubstituted-2-amino-5-methylpiperidine-3,4-diols and processes for the preparation thereof
This invention relates to (2R,3S,4R,5R)-2-amino-5-methylpiperidine-3,4-diol or a (2S,3S,4R,5R)-2-N-substituted-2-amino-5-methylpiperidine-3,4
-diol represented by the general formula (I): ...
|
|
|
6608196 |
Process for solid supported synthesis of pyruvate-derived compounds
Provided are processes for synthesizing structurally diverse pyruvate-derived compounds using a parallel approach on a solid phase support. Examples of such a solid phase support include resins...
|
|
|
6509003 |
Reagents for the determination of cerebral regional acetylcholinesterase activity
The present invention relates to N-alkylpiperidine derivatives represented by general formula (1) or (2); wherein R 1 represents optionally fluorinated lower alkyl; R 2 represents lower alkyl;...
|
|
|
6495597 |
Cytostatic agents
Compounds of formula (I) wherein R 4 is an ester or thioester group and R, R 1 , R 2 and R 3 are as defined in the specification, inhibit proliferation of tumor cells.
|
|
|
6492521 |
Hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same
Compounds and methods of preparing compounds of the formula: RZ—CO—CR a R b —(CR c R d ) n —NH—(Y) m —CO—A (I) wherein n is an integer from 1 to 15, m is either 0 or 1; R a , R b ,...
|
|
|
6489482 |
Process for the preparation of novel vinylic hindered amine light stabilizers
Novel hindered amine light stabilizers of the formula wherein R 1 is C 1 to C 8 alkyl, alkoxy, alkylphenyl, hydroxy alkyl, allyl, acyl, or cycloalkyl; R 2 is hydrogen or methyl; R 3 is...
|
|
|
6455573 |
Glycosidase inhibitors and methods of synthesizing same
A method for synthesizing Salacinol, its stereoisomers, and non-naturally occurring selenium and nitrogen analogues thereof having the general formula (I): The compounds are potentially useful...
|
|
|
6452016 |
Process for the preparation of 1,2,3,6-tetrahydro-2,2,6,6-tetramethylpyridine N-oxide
The invention relates to a process for the preparation of 1,2,3,6-tetrahydro 2,2,6,6-tetramethylpyridine N-oxide by the catalytic oxidation of 1,2,3,6-tetrahydro-2,2,6,6-tetramethylpyridine,...
|
|
|
6441177 |
Tertiary amines
Tertiary amines of the formula wherein A 1 , A 2 , A 3 , A 4 , M, p, T and Q are as defined herein, and acid addition salts thereof, have antimycotic and cholesterol-lowering activity.
|
|
|
6380182 |
Methods and compositions controlling biofouling using sulfamic acids
The invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one sulfamic acid or...
|
|
|
6348598 |
N-oxyl compounds, process for the preparation thereof, and process for inhibiting the polymerization of vinyl monomers with the same
Disclosed are novel N-oxyl compounds of the following formula (1). wherein n is an integer of 1 to 18; R 1 and R 2 are each hydrogen or methyl, but at least one of them is hydrogen; R 3 , R 4...
|
|
|
6344560 |
Nitroaromatic solubilizer for nitroxyls in aromatic solvents
A nitroaromatic compound is used to enhance the solubility of a nitroxyl compound in an aromatic hydrocarbon solvent.
|
|
|
6258133 |
Poly (oxyalkylene) pyridyl and piperidyl ethers and fuel compositions containing the same
A poly(oxyalkylene)pyridyl or piperidyl ether having the formula: ##STR1## wherein A is a nitrogen-containing ring selected from the group consisting of 3-pyridyl, 4-pyridyl, 3-piperidyl and...
|
|
|
6211378 |
Process for the synthesis of 4-substituted N-[(alk-2-en-1-yl)oxy]-and N-aralkyloxy-2,2,6,6-tetraalkylpiperidines
An environmentally friendly process for the preparation of the 4-functionalized N--OR derivatives of 2,2,6,6-tetraalkylpiperidines involves the hydrogen peroxide of the corresponding N--H compound...
|
|
|
6080864 |
Derivatives of 1-oxyl-4-hydroxy-2,2,6,6-tetramethylpiperidine
Selected derivatives of 1-oxyl-2,2,6,6-tetramethyl-4-hydroxypiperidine are surprisingly effective as inhibitors to prevent the premature polymerization of acrylic and methacrylic acids, their...
|
|
|
6071906 |
Imidino piperidine derivatives useful as nitric oxide synthase inhibitors
The current invention discloses useful pharmaceutical compositions containing amidino derivative useful as nitric oxide synthase inhibitors.
|
|
|
6066642 |
Dihydropyridine-, pyridine-, benzopyran-4-one- and triazoloquinazoline derivative, their preparation and their use as adenosine receptor antagonists
The present invention provides certain novel compounds, compositions, and a method of treating a mammal by blocking its adenosine receptors comprising administering at least one compound of the...
|
|
|
6046214 |
Heterocyclic compounds
Novel piperidine compounds are provided, and those compounds are useful in the treatment and/or prevention of diabetes, and especially non-insulin dependent diabetes (NIDDM or type 2 diabetes)...
|
|
|
6034067 |
Serine protease inhibitors
The invention relates to a compound having formula (I), wherein A, B, X, N, Z and Q are defined as described in the description. The compounds of the invention have anticoagulant activity and can...
|
|
|
6020344 |
Enzyme inhibitors and methods of use
Novel enzyme-inhibitory compounds are disclosed. The subject invention further pertains to methods and compositions for the inhibition of bacteria, viruses, parasites, and other pathogens.
|
|
|
6008359 |
Piperidine antioxidants and compositions therewith for preventing the fading of artificial hair dye
Piperidine antioxidants and compositions therewith for preventing the fading of artificial hair dye are described herein.
|
|
|
6001905 |
Polyalkylene glycol group-containing hindered amines
A description is given of compounds of formula 1 ##STR1## and of compounds of formula 2 ##STR2## wherein X, Y and Z and the radicals R 1 and also m and n have the meanings claimed in claim 1. The...
|