Matches 1 - 50 out of 109 1 2 3 >
Match Document Document Title
7077873 Composition for the dyeing of human keratinous fibres comprising a monocationic monoazo dye  
A subject-matter of the disclosure is a novel composition for the dyeing of human keratinous fibres, for example, the hair, comprising a monocationic monoazo dye of formula (I)...
7034041 Substituted 4-phenyl-1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridine  
Substituted 4-phenyl-1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridine (compounds), methods for the production thereof, pharmaceutical compositions containing said compounds, and methods of...
6953856 Process for the preparation of 1-benzyl-4-(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCI)  
A process for the preparation of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl] methyl piperidine hydrochloride (Donepezil HCl) is disclosed. 5,6-Dimethoxy-2-(pyridin-4-yl) methylene inda-1-one is...
6686503 Methods for the synthesis of highly substituted 2,4-dioxopiperidine libraries  
The invention relates to methods of synthesizing libraries of diverse and complex highly substituted 2,4-dioxopiperidine compounds of the general formula: wherein R 1 , R 2 and R 3 are as...
6649765 Process for the preparation of 1-benzyl-4(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCL)  
A process for the preparation of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride (Donepezil HCl). 5,6-Dimethoxy-2-(pyridin-4-yl)methylene inda-1-one is hydrogenated with a...
6617454 Process for the preparation of amine oxides  
The present invention provides a process for the preparation of amine oxide by reacting a tertiary or a secondary amine with hydrogen peroxide as an oxidant in the presence of a recyclable...
6583286 Method for hydrogenating unsaturated heterocyclic compounds  
A process for hydrogenating an unsaturated heterocyclic compound or a mixture of two or more thereof by contacting the unsaturated heterocyclic compounder the mixture of two or more thereof with a...
6458954 Process for preparing piperidines  
Piperidines are prepared in an advantageous manner by catalytic hydrogenation of activated pyridines in the presence of palladium catalysts if the palladium catalyst is palladium-on-carbon and the...
6437136 Process for the preparation of (−)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)piperidine  
Disclosed is a method for producing (−)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-piper idine characterized in that 1-methyl-piperidine-4-one is converted into hydrobromide, subsequently...
6348630 Method for purifying hexamethylenediamine in mixtures of hexamethylenediamine and an unsaturated cyclic imine  
The level of an unsaturated cyclic imine (I) of the formula (I) where R 1 is alkenyl having 3, 4, 5, 6, 7, 8, 9, 10, 11 carbon atoms belonging to the ring system, in a mixture comprising...
6268501 Process for the preparation of hydroxyethylcyclohexanes and hydroxyethylpiperidines  
Hydroxyethylcyclohexanes which can optionally contain a nitrogen atom in the cyclohexane ring are obtained in a particularly selective manner by catalytic hydrogenation of the corresponding...
6258955 Process for preparing 2-piperidineethanol compounds  
Described are preferred processes for producing 2-piperidineethanol compounds by hydrogenation of corresponding 2-pyridineethanol compounds. The preferred processes are conducted in the presence of...
6225473 Method for producing (-)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-piperidine  
Disclosed is a method for producing (-)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-piperid ine characterised in that 1-methyl-piperidine-4-one is converted into hydrobromide, subsequently...
6180759 Process for the preparation of azacycloalkylakanoyl pseudotetrapeptides  
This invention is directed to a process for preparing a pseudotetrapeptide of formula I ##STR1## or a salt or prodrug thereof wherein ##STR2## is optionally nitrogen protected azaheterocyclyl;...
6172233 Process for making paroxetine  
Compounds of structure (2) are prepared by reaction of an arecoline analogue of structure(4) with an organometallic compound containing an X-substituted phenyl group, such as a compound of...
6080863 Process for producing piperidine  
A process for activating a hydrogenation catalyst in the presence of an activation agent containing a piperidine compound is disclosed. The thus-activated hydrogenation catalyst is employed as a...
5962689 Stereoselective and useful preparation of 3-substituted 4-aryl piperidine compounds  
This invention relates to new stereoselective processes for preparing 3-substituted-4-aryl piperidines and methods for controlling the absolute stereochemistry at the C-3 and C-4 positions of the...
5856492 Efficient synthesis of a chiral mediator  
An efficient method for the quantitative preparation and isolation of a compound of formula I ##STR1## or its enantiomer, a chiral mediator used in enantioselective synthesis.
5710277 Process for R (+) 1,2,3,6-tetrahydro-4-phenyl-1- (3-phenyl-3-cyclohexen-1-yl)methyl!pyridi ne, a central nervous system agent  
An improved process for the preparation of R(+)1,2,3,6-tetrahydro-4-phenyl-1- (3-phenyl-3-cyclohexen-1-yl)methyl!pyri dine by a novel synthesis is described where...
5686616 Process for preparing an optically active amine  
A novel process for preparing an optically active amine by asymmetric hydrogenation of an imine compound, such as an imine compound prepared by condensing benzylamine and acetophenone, in the...
5686615 Stereoselective preparation of substituted piperidines  
Novel processes are disclosed for the stereoselective preparation of substituted piperidine derivatives of the formulae ##STR1## wherein R 1 and R 2 are defined as below, useful as substance P...
5663351 Process for the continuous preparation of 2,2,6,6-tetramethylpiperidine  
Process for the continuous preparation of 2,2,6,6-tetramethylpiperidine. The reduction of triacetonamine with hydrazine also succeeds continuously by reactive distillation if the hydrazone is first...
5663350 Process for the preparation of intermediates useful for the synthesis of histamine receptor antagonists  
The present invention relates to a novel process for the preparation of highly potent histamine receptor antagonists, in particular histamine H 3 -receptor antagonists. Also disclosed is a novel...
5663349 Preparation of substituted piperidenes  
Novel processes are disclosed for the preparation and resolution of substituted piperidines of the formula ##STR1## wherein R 1 and R 2 are defined as below, and related compounds, as well as...
5606064 Process for the preparation of benzyl-piperidylmethyl-indanones  
The invention relates to a new process for the preparation of benzyl-piperidylmethyl-indanones known as medicaments, which is characterized in that the appropriately substituted pyridinium salts...
5374728 Process for the preparation of 2-aminomethylpiperidine  
A process for the preparation of 2-aminomethylpiperidine by catalytic hydrogenation of 2-cyanopyridine in the presence of a cobalt-containing catalyst at elevated temperature and under elevated...
5312923 Process for preparing fibrinogen receptor antagonists  
The invention is a highly efficient synthesis for making compounds of the formula: ##STR1## wherein: R 1 is a six membered saturated or unsaturated heterocyclic ring containing one or two...
5039803 Process for preparing aryl-substituted piperidines  
A process for preparing a compound of formula (I): ##STR1## in which Ar represents an aryl or substituted aryl group and R 3 represents an alkyl group, which comprises reducing a compound of...
4912220 Processes for making nitroaryl carbonyl compounds and nitrodihydroaryl carbonyl intermediates thereto  
Nitroaryl carbonyl Formula (IIA) compounds, their nitrodihydroaryl carbonyl Formula (I) intermediates, processes for preparing Formula (II) compounds, and a process for preparing Formula (I)...
4861893 Chemical process  
A process is disclosed for the preparation of a compound of formula (I): ##STR1## where Ar is aryl or substituted aryl and R 3 and R 4 are the same or different and each is alkyl, which process...
4678638 Highly branched amino hexahydropyridines  
This invention relates to amino hexahydropyridines, and to the preparation and use thereof as corrosion inhibitors.
4675409 Process for the preparation of encainide  
A new and novel process for the preparation of encainide (4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]-benzanilide) has been developed. The process utilizes α-picoline, O-nitrobenzaldehyde, and...
4659862 Process of preparing nitrodihydroaryl carbonyl compounds  
Nitroaryl carbonyl Formula (IIA) compounds, their nitrodihydroaryl carbonyl Formula (I) intermediates, processes for preparing Formula (II) compounds, and a process for preparing Formula (I)...
4581456 Processes for preparing picenadol precursors and novel intermediates thereof  
The present invention relates to processes for preparing precursors of picenadol, (±)3-(1,3α-dimethyl-4α-propyl-4β-piperidinyl)phenol, hydrochloride, a known analgesic. Certain of the compounds...
4377691 Process for the preparation of 1-(4-hydroxyphenyl)-2-(4-benzylpiperidino)-1-propanol and acid-addition salts thereof  
A process for the preparation of 1-(4-hydroxyphenyl)-2-(4-benzylpiperidino)-1-propanol (i.e. ifenprodil) and acid-addition salts thereof, characterized by brominating 4'-hydroxypropiophenone in a...
4276419 Process for the preparation of C-substituted pyridines and/or hydrogenated C-substituted pyridines, C-substituted quinolines and/or hydrogenated quinolines  
An improved process for the preparation of pyridines and/or hydrogenated pyridines that have been substituted with a hydrocarbon group at one or more carbon atoms, γ-cyanoketone, in a gaseous...
4245099 2-Acyl-6-aminomethylphenol derivatives  
A 2-acyl-6-aminomethylphenol derivative having the formula (I): ##STR1## wherein R 1 represents a straight chain or branched chain alkyl group of 1 to 6 carbon atoms unsubstituted or substituted...
4191828 Process for preparing 2-(2,2-dicyclohexylethyl)piperidine  
2-(2,2-Dicyclohexylethyl)piperidine is prepared via the catalytic hydrogenation of 2-(2,2-diphenylethenyl)pyridine in a single step. High yields are obtained using a rhodium supported catalyst.
4110331 Method of producing the hydrochloride of N-methyl piperidine-2-carboxylic acid-2,6-xylidide  
Method for producing the hydrochloride of N-methyl piperidine-2-carboxylic acid-2,6-xylidide which include hydrogenating picolinic acid-2,6-xylidide in the pyridine ring in the presence of HCl to...
4108997 Diuretic [2]benzopyrano[4,3-b]pyridines and process therefor  
[2]Benzopyrano[4,3-b]pyridine derivatives characterized by having a 2,3,4,4a,6,10b-hexahydro-1H-[2]benzopyrano[4,3-b]pyridine nucleus bearing substituents at positions 1,6,8 and 9 are disclosed....
4101555 Process for increasing the cis content of a mixture of cis and trans isomers of S-isopropyl-1-(5-ethyl-2-methylpiperidinecarbothioate)  
A mixture of cis and trans isomers of S-isopropyl-1-(5-ethyl-2-methylpiperidinecarbothioate) has been found to have improved herbicidal properties in contrast to the trans isomer alone. Preferably...
4097481 Tertiary amide derivatives of pyrrolidine and piperidine  
Certain compounds in which a carbon atom of a pyrrolidine or piperidine ring is bonded directly or through a methylene group to the completely substituted nitrogen of a substituted benzamido group,...
4092318 Indantetrol derivatives  
Compounds are provided having the structure ##STR1## WHEREIN N IS 1, 2 OR 3, M AND M' ARE 0, 1 OR 2, R 1 , R 2 , R 3 and R 4 may be the same or different and can be hydrogen, lower alkyl,...
4081450 1,3,4-Trisubstituted-4-arylpiperidines and their preparation  
Novel 1,3,4-trisubstituted-4-arylpiperidines are prepared by alkylating a 2,3-disubstituted-3-arylpyrroline to afford a 1,2,3-trisubstituted-3-aryl-1-pyrrolinium salt, reacting the salt with...
4071524 Derivatives of urea  
Certain compounds in which a carbon atom of a pyrrolidine or piperidine ring is bonded directly or through a methylene group to the nitrogen of a phenyl-substituted urea, and their pharmaceutically...
4061641 Ureidopiperidino-ketoalkyl indoles  
The invention provides compounds of general formula I ##STR1## and pharmaceutically acceptable acid addition and quaternary ammonium salts thereof, wherein R represents hydrogen or lower alkyl, R 1...
4021431 3-(Piperidino-lower-alkyl)-indoles  
1-Acyl-3-(amino-lower-alkyl)indoles, useful as anti-inflammatory agents, are prepared either by acylation of a 3-(amino-lower-alkyl)indole; by Fisher indole synthesis from an N'-acylphenylhydrazine...
4000143 Substituted piperidines  
The compounds are of the heterocyclic class of 2-phenethylpiperidines having an amido substituent in the ortho position of the phenethyl moiety. Substituents in the ortho position include...
3982001 4-(3.4-Methylene dioxy phenyl)-piperidines  
This invention provides new compounds of formula I, ##SPC1## wherein R 1 and R 2 are the same or different and are in each case hydrogen, halogen, lower alkyl, hydroxy or lower alkoxy R 3 is...
3933830 Process for the synthesis of 4-(2-pyridylamido ethyl) piperidines  
Disclosed herein is an improved process for the preparation of known hypoglycemic piperidinesulfamylureas of the structure ##EQU1## wherein R is selected from the group consisting of...
Matches 1 - 50 out of 109 1 2 3 >