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5075324 |
Aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical composition containing them
1,4-dihydropyridines of formula I ##STR1## wherein X is --CO 2 R 1 , cyano, nitro, --COCH 3 ; each of R and R 1 , which are the same or different, is a primary, secondary or tertiary, saturated...
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5066663 |
Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof acting at muscarinic receptors
Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as...
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5066665 |
Substituted isoxazolidin-3-ones and derivatives thereof acting at muscarinic receptors
Substituted isoxazolidin-3-ones and derivatives thereof are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as centrally acting...
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5061718 |
Benzothiazolylmethoxy compounds, pharmaceutical compositions comprising the same and their use as anti-inflammatory or anti-allergenic agents
The invention relates to an anti-inflammatory or antiallergic composition containing a compound of the formula ##STR1## wherein A is ##STR2## R 1 is aryl which may have cyano or carbamoyl, or...
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5045548 |
Quinolyl methoxy compounds and their use as antiasthmatic agents
The invention relates to a method of treating asthma comprising administering a compound of the formula: ##STR1## wherein A is ##STR2## R 1 is quinolyl, R 2 is hydrogen or lower alkyl, R 3 is...
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5032590 |
Substituted hydroxylamines
Substituted hydroxylamines of the formula ##STR1## in which R 1 stands for an aromatic or heterocyclic radical, are especially useful in the treatment of hyperlipoproteinaemia, lipoproteinaemia...
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5024736 |
Process for electroplating utilizing disubstituted ethane sulfonic compounds as electroplating auxiliaries and electroplating auxiliaries containing same
A process in which disubstituted ethane sulfonic compounds are employed as electroplating auxiliaries in electroplating. The compounds for use in combination with the claimed process have the...
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5002957 |
Azaneophyl sulfides, and their use as pesticides
Azaneophyl and silazaneophyl sulfides, processes for their preparation, agents containing them, and their use as pesticides. Compounds of the formula I, their optical isomers and mixtures thereof...
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5001129 |
Oxazoloquinoline compounds and therapeutic application thereof
The present invention relates to tricyclic carbamates coplying with the formula ##STR1## in which n=0, 1 or 2, p=0 or 1, R 1 represents a hydrogen atom; a group which is alkyl in C 1 -C 4 ...
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4996324 |
Preparation of alkanols which are substituted in the 1 position by aromatic or heterocyclic radicals
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4985438 |
Pyridyl-and/or pyridoyl-(piperid-4-yl) ureas and analogues thereof
The invention concerns the preparation of compounds of formula ##STR1## and acid addition and quaternary ammonium salts thereof, wherein the dotted line represents an optional bond, Ar represents a...
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4970307 |
Process for formation of base and light-sensitive material
A process for formation of a base from a base precursor, which comprises decomposing the base precursor in the presence of a catalyst. The base precursor has the following formula (I) or (II): (R...
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4965274 |
Quinolyl methoxy compounds, processes for preparation thereof and pharmaceutical composition comprising the same
The invention relates to a method of treating arteriosclerosis or pancreatitis comprising administering a compound of the formula: ##STR1## wherein A is ##STR2## R 1 is quinolyl, R 2 is hydrogen...
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4963566 |
Benzimidazolyl-sulfinyl-tetrahydroquinolines
A hydroquinoline compound of the formula (1): ##STR1## wherein R 1 , R 2 , R 3 , A, l, m and n are as defined or its pharmaceutically acceptable salt, composition containing the compound and...
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4963576 |
Dithioacetal compounds, processes for preparation thereof and pharmaceutical composition comprising the same
The invention relates to dithioacetal compounds having 5-lipoxygenase-inhibiting activity, of the formula: ##STR1## wherein R 1 is lower alkyl, di-(lower)alkylamino, aryl, or heterocyclic group...
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4962203 |
2-substituted quinolines useful as leukotriene antagonists
Compounds having the formula: ##STR1## are selective antagonists of leukotrienes of D 4 . These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents.
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4959482 |
Pyrrolidinone compounds and pharamaceutical compositions containing same
A novel class of pyrrolidin-2-one and piperidin-2-one compounds in which the nitrogen atom is bonded to an oxyphenyl radical haivng tertiary-alkyl and tri-methylsilyl substituents. The compounds...
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4952695 |
Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid, intermediate for antibacterials
1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-c
arboxylic acid and ester as pharmaceutical intermediate.
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4943671 |
Reductive dehalogenation of organic halogen compounds
Organic halogen compounds in which one or more halogen atoms are covalently bonded to the carbon are subjected to reductive dehalogenation by reaction with a hydrocarbon in the presence of carbon...
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4943502 |
Photosensitive recording material suited for use in electrophotography containing dihydroquinoline charge transport compounds
An electrophotographic recording material which comprises an electrically conductive support having thereon a double layer of a charge generating layer in contiguous relationship with a charge...
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4940706 |
2,4-disubstituted 1,3-dioxolanes and pharmaceutical use
The present invention describes novel 2,4-disubstituted 1,3-dioxolanes having the formula I ##STR1## wherein R 1 represents a long chain alkyl group; X is a covalent single bond, a carbonyl group,...
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4929738 |
Thienyl and furyl containing derivatives
Microbicidal substituted pyrazolin-5-ones of the formula ##STR1## in which R 1 and R 2 independently of one another each represent hydrogen, alkyl, alkenyl, alkinyl, cyanoalkyl, hydroxyalkyl,...
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4921959 |
Anthraquinone compounds and polarizing film containing the same
An anthraquinone compound represented by formula: ##STR1## wherein R and X are as defined in the specification, and a polarizing film containing the same. The anthraquinone compound exhibits...
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4904786 |
Quinoline compounds as antiallergic and antiinflammatory agents
There are disclosed compounds of the formula ##STR1## wherein R 1 is ##STR2## n is 0-5; R 2 is hydrogen, loweralkyl, loweralkoxy, lower alkoxycarbonyl, trifluoromethyl, nitro, cyano or halo; R...
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4889953 |
Glycerol derivatives, their production and use
Compounds of the formula: ##STR1## wherein R 1 is a higher alkyl group which may be substituted; R 2 is a hydrogen, a lower alkyl group which may be substituted, a lower alkanoyl group which may...
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4885368 |
Radical ion salts
Novel radical ion salts of the formula ##STR1## wherein R 1 , R 2 , R 3 and R 4 independently of one another are each hydrogen, methyl, ethyl, phenyl, methoxy, ethoxy, fluorine, chlorine or...
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4874769 |
Quinolinyl ether or thioether tetrazoles as agents for the treatment of hypersensitive ailments
This invention relates to certain quinolyl ether and thioether tetrazoles and their use as valuable pharmaceutical agents for the treatment of hypersensitive ailments, particularly as lipoxygenase...
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4873337 |
N-substituted derivatives of 2-(pyridylalkenesulfinyl) benzimidazoles as gastric antisecretory agents
The present invention provides novel N-substituted derivatives 2-(pyridylalkylenesulfinyl)benzimidazoles with gastric acid inhibiting effects.
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4863522 |
Novel compositions based on C.I. Pigment Red 177
A composition comprising (a) a dianthraquinonyl pigment of formula I ##STR1## (b) a compound of formula II ##STR2## wherein X ♁ is H ♁ or a group of formula M n ♁ /n or N ♁ (R)(R 1 )(R 2...
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4861742 |
Bifunctional alkali metal compounds, preparation and use thereof as polymerization initiators
Bifunctional initiators for anionic polymerization are prepared by reacting an alkenylaromatic compound of the general formula I ##STR1## where Ar is aromatic hydrocarbyl which may be substituted...
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4851409 |
2-substituted quinoline dioic acids and pharmaceutical compositions
Compounds having the formula: ##STR1## are antagonists of leukotrienes and inhibitors of their biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and...
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4845118 |
Substituted thienoimidazole derivatives, pharmaceutical compositions containing them, and their use as inhibitors of gastric acid secretion
The invention relates to compounds of the formula ##STR1## in which A represents ##STR2## T denotes --S--, --SO-- or --SO 2 --, and R 1 to R 9 have the meanings given in the description, to a...
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4839369 |
Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
Aryl and Heteroaryl Ethers are used for their anti-inflammatory and anti-allergic properties.
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4826987 |
Pyridyl and quinoline derivatives
The present invention relates to compounds of formula I ##STR1## in which formula I X stands for O, S, ##STR2## R 1 and R 2 which can be the same or different stand for hydrogen, straight or...
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4820841 |
Chromogenic quinoline compounds
Disclosed herein is a novel chromogenic compound of the formula: ##STR1## wherein R represents an alkyl group of 6 to 12 carbon atoms or benzyl group, and ring A and ring B in the quinolyl group...
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4810804 |
Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity
Retinoid-like activity is exhibited by compounds of the formula ##STR1## where X is S, O or NR 1 where R 1 is hydrogen or lower alkyl; n is 0-5; R is H or lower alkyl and A is H, --COOH or a...
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4808603 |
3,5-diacyl-2,6-dialkyl-4-aryl-1,4-dihydropyridines, their use, and pharmaceutical compositions thereof
Compounds of the formula ##STR1## in which R represents a carbocyclic or heterocyclic aryl radical, R 1 represents lower alkyl, one of the groups R 2 and R 3 represents lower alkyl and the other...
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4794188 |
Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity
Compounds of the formula: Ar 1 -X-Ar-Z-(R) n ' and salts thereof, wherein Ar 1 is a nitrogen, sulfur or oxygen heterocyclic ring; Ar is a phenyl ring or a nitrogen, oxygen or sulfur...
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4792555 |
Phospholipase A.sub.2 inhibitors
There are disclosed compounds of the formula ##STR1## wherein R 1 is lower alkyl, lower alkoxycarbonyl lower alkyl, aralkoxycarbonyl, aralkoxycarbonyl lower alkyl or indol-2-yllower alkyl; R 2 ...
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4792568 |
Aryl pyrroles as useful antiallergy compounds
This invention relates to new lipoxygenase inhibitors possessing anti-inflammatory and anti-allergic properties. The present new compounds are of the formula: ##STR1## and salts thereof; wherein, R...
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4782169 |
4,7-dioxatricyclo(3.2.1.0.sup.3,6)octane ether
Compounds of the Formula I, II, III, VI and VII ##STR1## wherein the symbols have defined meanings are herbicides, plant growth regulators or intermediates thereof.
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4778931 |
Certain [3-(1-hydroxy hexyl-tetrahydro)naphthalenes], the corresponding naphthalenes having anti-inflammatory and anti-allergic activity
The invention relates to several aryloxy-alkane alcohols, for example 1-(3-(1-hydroxy-1-methylhexyl) phenoxy methyl)-2-methoxy-naphthalene, 2-(1-(3-(1-hydroxy-2,2-dimethylhexyl)phenoxy)ethyl...
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4778803 |
Nitrogen-arylmethoxy-thiophene derivatives and acid addition salts thereof, and pharmaceutical preparations containing these compounds
The invention relates to new nitrogen-arylmethoxy-thiophene derivatives of the formula I ##STR1## wherein the R--CH 2 --O-group is in position 4 or 5 of the thiophene ring, R denotes a...
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4772703 |
2-(phenoxymethyl)-quinazolines as antiallergic and antiinflammatory agents
There are disclosed compounds of the formula ##STR1## wherein ##STR2## R 2 is hydrogen, loweralkyl, loweralkoxy, lower alkoxycarbonyl, trifluoromethyl, nitro, cyano or halo; R 3 is hydrogen or...
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4769461 |
Quinolinyl benzene hydroxamic acids as anti-inflammatory/antiallergic agents
There are disclosed compounds of the formula ##STR1## wherein W represents a covalent bond or ##STR2## X is N or CR 2 ; Y is O, S, NR 2 or C(R 2 ) 2 when n=0, or N or CR 2 when n=1 Z is...
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4764616 |
Benzopyrrolobenzodiazepines and quinobenzodiazepines
The invention relates to benzopyrrolobenzodiazepines and quinobenzodiazepines of the formula ##STR1## where X and Y may be the same or different and each is hydrogen, halogen, CF 3 , lower alkyl,...
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4754043 |
Oxazole and thiazole naphthalenes as antiallergic agents
There are disclosed compounds of the formula ##STR1## wherein X is --CH 2 CH 2 --, --CHCH--, ##STR2## Z is CR or N, where n=1; or Z is O,S, or NR, when n=0; R is hydrogen or loweralkyl; n...
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4748272 |
Phenoxyphenylacetates for use as potential modulators of arichidonic acid pathways
This invention relates to new lipoxygenase inhibitors possessing anti-inflammatory and anti-allergic properties. The present new compounds are of the formula: ##STR1## and salts thereof; wherein ...
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4732978 |
Novel substituted naphthyloxymethyl quinoline derivatives as anti-inflammatory and antiallergy agents
There are disclosed compounds having the formula ##STR1## wherein X is CR or N when n=1; or X is O, S, NR or CR when n=0; R is hydrogen or lower alkyl; Y is --CH 2 --, --S--, --O-- or...
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4713393 |
Phenylpropyl-2,3-dihydrobenzofurans useful as anti-inflammatory agents
Phenylalkyl-2,3-dihydrobenzofurans and analogs were prepared by (1) nucleophilic substitution involving an appropriately substituted 2,3-dihydrobenzofuranol (or 2,3-dihydrobenzopyranol) and a...
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