Matches 201 - 250 out of 491 < 1 2 3 4 5 6 7 8 9 10 >
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5932587 Heterocyclic-fused pyridines  
The heterocyclic-fused pyridines are prepared by reaction of the corresponding heterocyclic-fused pyridine aldehydes with appropriately substituted Grignard or Wittig reagents. The...
5925653 Substituted pyridines and pyrimidines processes for their preparation and their use as pesticides and fungicides  
Substituted pyridines and pyrimidines, processes for their preparation and their use as pesticides and fungicides. The invention relates to compounds of the formula ##STR1## in which A is N or CH,...
5908842 Substituted 2-acylamino-pyridines as inhibitors of nitric oxide synthase  
Substituted 2-acylaminopyridine compounds and pharmaceutically acceptable salts which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders.
5889022 Indole, indoline and quinoline derivatives with 5HT.sub.1D (anti-depressive) activity  
Novel indole, indoline and quinoline derivatives of formula (I) processes for their preparation, pharmaceutical compositions containing them, and their use in medicine is disclosed. A structurally...
5874382 Cyclic sulfonamide herbicides  
Compounds of Formula I and II, and their agriculturally-suitable salts, are disclosed which are useful for controlling undesired vegetation ##STR1## wherein X is a direct bond; O; S; NH; N(C 1 -C...
5874581 2-silyloxy-tetrahydrothienopyridine, salt thereof and process for preparing the same  
A 2-silyloxy-4,5,6,7-tetrahydrothieno 3,2-c!pyridine represented by the formula (I): ##STR1## wherein R 1 , R 2 and R 3 each independently represent an alkyl group having 1 to 10 carbon atoms or...
5872128 Stabilized composition of ticlopidine hydrochloride  
A novel pharmaceutical composition including thieno-pyridine derivatives, primarily ticlopidine hydrochloride, having no other organic or inorganic acid stabilizing agents or metal stearates. The...
5856335 Substituted aminothienopyridines, pharmaceutical composition and use  
This application relates to compounds of the formula ##STR1## wherein R 1 , R 2 , R 3 , m and n are as defined in the specification which are useful as modulators of neurotransmitter function such...
5837710 HIV protease inhibitors  
HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These...
5827857 Pyrido-fused thienyl- and furanyl-oxazolidinones  
The present invention relates to new pyrido-fused thienyl- and furanyl-oxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
5824677 Substituted amino alcohol compounds  
Disclosed are compounds having a straight or branched aliphatic hydrocarbon structure of formula I: ##STR1## In formula I, n is an integer from one to four and m is an integer from four to twenty....
5824652 Heterocyclic acyldipeptides, processes for the preparation thereof and pharmaceutical compositions containing the same  
Heterocyclic acyldipeptides of the formula I ##STR1## wherein Z represents an oxygen or sulphur atom or a --CH 2 -group; R 1 , R 2 and R 3 individually represent hydrogen or certain organic...
5811427 Heterocyclic N-acetonylbenzamides  
Certain N-acetonylbenzamides and their use as fungicides are disclosed. The N-acetonylbenzamides disclosed contain a heterocyclic ring fused to an aromatic ring. These compounds are particularly...
5801115 Catalyst composition and methods for using and preparing same  
A catalyst composition for a catalyst that reduces the emissions of sulfur compounds from industrial processes is disclosed. This catalyst is a spheroidal particle comprised of a mixture of...
5789587 Heterocyclic-fused lactams promote release of growth hormone  
There are disclosed certain novel compounds identified as heterocyclic-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the...
5786481 N-alkyl and N-acyl derivatives of 3,7-Diazabicyclo- 3.3.1!nonanes and selected salts thereof as multi-class antiarrhythmic agents  
3,7-Diazabicyclo 3.3!nonanes and selected derivatives thereof of the general formula: ##STR1## wherein Q=S; Z=CH 2 ; and Y equals an N-acyl or N-alkyl group are disclosed as multiclass...
5767141 Substituted propane derivatives, a process for their preparation and the use of the compounds for treating diseases  
Substituted propane derivatives, a process for their preparation and the use of the compounds for treating diseases Propane derivatives of the formula I ##STR1## in which the radicals have the...
5760054 Alpha IC adrenergic receptor antagonists  
This invention relates to certain novel compounds and derivatives thereof, their synthesis, and their use as selective alpha-1C adrenergic receptor antagonists. One application of these compounds...
5756515 Dioxo-thiopyrano-pyridine-carboxylic acid derivatives and their use as medicaments  
Dioxo-thiopyrano-pyridine-carboxylic acid derivatives are prepared by reacting appropriate aldehydes with aminocrotonic acid esters and tetrahydrothiopyran-3-one-1,1-dioxide and oxidizing the...
5753670 Carboxylic acid compound having condensed ring, salt thereof and pharmaceutical use thereof  
A novel carboxylic acid compound having a condensed ring; which is represented by the formula (I) ##STR1## wherein each symbol is as defined in the specification, a pharmacologically acceptable...
5750539 Heteroaryl diol acids as leukotriene antagonists  
Compounds of Formula I: ##STR1## are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are...
5747486 Thienopyridine or thienopyrimidine derivatives and their use  
This invention provides an anti-inflammatory agent, particularly an agent for treating arthritis, and a bone resorption inhibiting agent, containing a thienopyridine or thienopyrimidine derivative...
5744471 Pyridazion quinoline compounds  
The present invention relates to compounds, pharmaceutical compositions and methods of using compounds of formula (I) in the treatment and/or prevention of certain diseases or conditions. In...
5744479 Thienopyridine compounds which have useful pharmaceutical activity  
The present thienopyrimidine derivatives and compositions having gonadotropin-releasing hormone antagonistic activity are useful as propylactics or therapeutic agents for the prevention or...
5734057 HIV protease inhibitors and intermediates  
The present invention provides HIV protease inhibitors, intermediates for preparing HIV protease inhibitors. The enzyme, HIV protease, represents a viable target for the inhibition of HIV viral...
5714495 Pyridine compounds as melatonergic agents  
The invention relates to a compound selected from those of formula (I): ##STR1## in which: R 1 , R 2 , R 3 , R 4 , R 5 and X are as defined in the description and medicinal product containing the...
5714437 Epoxyphenol derivatives and herbicides containing them as active ingredients  
Novel compounds of the formula 1! are disclosed, wherein X is hydrogen, fluorine or chlorine; Y is fluorine, chlorine or bromine; R 1 is hydrogen or C 1 -C 3 alkyl; and R 2 and Q are various...
5693460 Silver halide photographic elements containing dioxide compunds a stabilizers  
This invention provides a silver halide photographic element comprising a silver halide emulsion in reactive association with a dioxide compound represented by the following formula: ##STR1##...
5674878 Anellated dihydropyridines and the use thereof for the production of pharmaceutical preparations  
Compound of general formula I ##STR1## wherein A is a benzo or thieno group; R 1 is (C 4 -6)cycloalkyl, (C 4 -6)cycloalkyl-(C 1 -5)alkyl or ##STR2## R 2 , m, R 3 , R 4 , R and u are defined as...
5674811 Cyanoketone derivative and herbicide containing it as an active component  
A cyanoketone derivatives of the following formula (1) ##STR1## which are characterized by excellent herbicidal activity and effectiveness against a variety of broad leafed weeds, including...
5663183 N-(3-Aminopropyl)-N-phenyl-5,6,7,8-tetrahydronaphthalene-2-carboxamide derivatives, their preparation and their therapeutic use  
Compounds of the formula: ##STR1## in which R 1 represents a hydrogen or halogen atom or a methyl or C 1 -C 4 alkoxy group, R' 1 represents a hydrogen or halogen atom, R" 1 represents a...
5656638 Telomerase inhibitors  
Methods and compositions for treating cancer and other diseases in which inhibition of telomerase activity can ameliorate disease symptoms or prevent or treat the disease relate to compounds...
5656637 Thiazole derivatives  
A novel thiazole derivative represented by general formula (I), which has a selected agonistic activity for 5-HT 3 receptor, a pharmaceutical composition thereof, and a process for producing the...
5650412 HIV protease inhibitors useful for the treatment of AIDS  
Compounds of formula ##STR1## are HIV protease inhibitors. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS, either as compounds,...
5635511 Treatment of heart rhythm disorders by administration of 3-phenylsulfonyl-3,7-diazabicyclo[3.3.1]nonane compounds.  
The use of 3,7,9,9-tetrasubstituted 3-phenylsulfonyl-3,7-diazabicyclo[3.3.1]nonane compounds for treating cardiac arrhytmias in larger mammals, including humans; novel antiarrhythmically active...
5624934 Protease inhibitors  
The present invention provides novel HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of treating and/or preventing HIV infection.
5623074 Substituted tetrahydroisoquinoline compounds, and process for producing them, and composition containing them  
A compound of the formula (I) or its salt and a process for producing the compounds; The compounds have the effect to dilate neophrovascular tracts; ##STR1## Wherein ##STR2## represents the formula...
5616590 Plant microbicides  
Compounds of the formula I ##STR1## in which a) X is CH and Y is N; or b) X is N and Y is CH; and in which Z is a C 1 group to which there are bonded 1-3 halogen atoms or 1-3 substituted or...
5607944 Bicyclic heterocyclic compounds, pharmaceutical preparations containing these compounds and processes for their preparations  
The invention relates to bicyclic heterocyclic compounds of general formula ##STR1## wherein A to F, Y 1 and Y 2 are defined as in claim 1, the tautomers thereof, the stereoisomers thereof...
5607943 Annelated dihydropyridines and the use thereof for preparing pharmaceutical preparations  
A compound of formula I ##STR1## wherein A denotes a benzo, indolo or thieno group; R 1 denotes thienyl or the group ##STR2## wherein R 7 , R 8 and R 9 independently of one another may...
5602144 Thienopyridones  
Thienopyridone derivatives of the formula I ##STR1## in which B is CH or N, ##STR2## is ##STR3## R is H, ##STR4## R 1 , R 2 and R 5 are in each case H, A or Hal, R 3 and R 4 are in each case H,...
5597823 Tricyclic substituted hexahydrobenz [e]isoindole alpha-1 adrenergic antagonists  
The present invention relates to a compound of the formula ##STR1## and the pharmaceutically acceptable salts thereof wherein W is a tricyclic heterocyclic ring system; which is an α-1 adrenergic...
5593943 Heteroaromatically condensed hydroxypyridonecarboxamides, their preparation and use as herbicides  
Heteroaromatically condensed hydroxypyridonecarboxamides of the structure I ##STR1## where the substituents and the ring Q have the following meanings: R 1 hydrogen, hydroxyl, substituted or...
5585385 Heterocyclic compounds, their production and use as tachykinin reactor antagonists  
A novel compound represented by the formula: ##STR1## wherein Ring A and Ring B respectively stands for an optionally substituted homo- or hetero-cyclic ring, and at least one of them stands for an...
5580871 4-Heteroaryl- 1,4-dihydropyridine compounds with calcium agonist and alpha.sub.1 -antagonist activity  
There are provided novel 1,4-dihydropyridine compounds, compositions containing them and methods of using them to treat congestive heart failure.
5573999 β-substituted cinnamic acid derivative  
β-Substituted cinnamic acid derivatives of the formula 1, ##STR1## where R 1 is alkyl, chlorine or bromine, --X-- is --O--, --S--, ##STR2## m is 0 or 1, --Y is --OR 4 , --O--NCR 5 R 6 , --NR...
5550162 N-(-3-aminopropyl)-N-phenyl-5,6,7,8-tetrahydro-naphthalene-2-carboxamide derivatives, their preparation and their therapeutic use  
Compounds of the formula: ##STR1## in which R 1 represents a hydrogen or halogen atom or a methyl or C 1 -C 4 alkoxy group, R' 1 represents a hydrogen or halogen atom, R" 1 represents a...
5545835 5,6-disubstituted-3-pyridylmethyl ammonium halide compounds useful for the preparation of 5-(substituted methyl)-2,3-pyridinedicarboxylic acids  
There are provided 5,6-disubstituted-3-pyridylmethyl ammonium halide compounds, a method for the preparation thereof and the use thereof for the preparation of 5-(substituted...
5543433 Azine-substituted phenylacetic acid derivatives and fungicides containing these  
Compounds of the formula I ##STR1## where X is hydrogen, halogen, alkyl, alkoxy, trifluoromethyl, cyano or nitro, Y is an amino, methylamino or dimethylamino group, Z is a group CHCH 3 ,...
5536839 (2-Imidazolin-2-yl) fused heteropyridine compounds  
There are provided novel (2-imidazolin-2-yl) fused heteropyridine compounds, and intermediate compounds for the preparation thereof, and a method for controlling a wide variety of annual and...
Matches 201 - 250 out of 491 < 1 2 3 4 5 6 7 8 9 10 >