Patents in Class 546/111

Matches 1 - 50 out of 73

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Match	Document	Document Title
1	7544696	Spermicidal and/or antifungal composition and methods of using the same Hexahydroindenopyridine compounds are provided which act as spermicides and/or fungicides, spermicidal and/or fungicidal compositions containing the same, and methods for killing motile sperm...
2	7528144	Molecules and methods for fluorescence microscopy The present invention provides molecules and methods for fluorescent microscopy and visualization of biomolecules, such as cholesterol. In a preferred embodiment, the present invention provides a...
3	7351711	Tricyclic indanyls as integrin inhibitors The present invention is directed to substituted indanyl compounds of Formula (I): Useful for treating integrin-mediated disorders such as, but not limited to unstable angina, thromboemboic...
4	6958328	Arylindenopyridines and related therapeutic and prophylactic methods This invention provides novel arylindenopyridines of the formula: , and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by reducing PDE activity in...
5	6515011	Thrombin inhibitors Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure: or a pharmaceutically acceptable salt thereof, e.g. where R 3 ...
6	6323227	Substituted N-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides This invention relates to compounds of formula ##STR1## which inhibit Factor Xa, to pharmaceutical compositions containing the compounds, and to the use of the compounds for the treatment of...
7	6248884	Extended rhodamine compounds useful as fluorescent labels Extended rhodamine compounds exhibiting favorable fluorescence characteristics having the structure ##STR1## are disclosed. In addition, novel intermediates for synthesis of these dyes are...
8	6063788	Bicyclic-fused pyridines Bicyclic-fused pyridines are prepared by introducing the appropriate side chain by reaction of the corresponding aldehydes with the aid of Wittig or Grignard reagents. The bicyclic-fused pyridines...
9	5965582	N-benzylindole and benzopyrazole derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunemodulating effect The N-benzylindole- and benzopyrazole derivatives of the general formula 1 ##STR1## possess anti-asthmatic, anti-allergic, anti-inflammatory and immunomodulating effect and are suitable for the...
10	5958972	Tricyclic inhibitors of matrix metalloproteinases Tricyclic compounds are described as well as methods for the preparation and pharmaceutical compositions of same, which are useful as inhibitors of matrix metalloproteinases, particularly...
11	5952336	Hexahydroindenopyridine compounds having antispermatogenic activity Hexahydroindenopyridine compounds having the following formula and relative stereochemistry ##STR1## where R 1 is C 1 -6 alkyl; R 2 is hydrogen or C 1 -6 alkyl; R 3 is carboxyl or a group which...
12	5854274	Tricyclic heterocyclic sulfonamide and sulfonic ester derivatives Novel tricyclic heterocyclic sulfonamide derivatives and sulfonic ester derivatives which have excellent antitumor activity and are represented by the following general formula (I) and processes...
13	5808015	Pyridone-methide azo dyestuffs with improved dyeing and printing properties for hydrophobic synethic fiber materials Dyestuffs of the formula ##STR1## wherein D is the radical of a carbo- or heterocyclic diazo component, X represents O, NH, NT, NCOT, NCCH 2 T or NSO 2 T, are preferably suitable, if m=n=l=o,...
14	5663344	Method for the synthesis of huperzine A and analogs thereof and compounds useful therein The present invention relates to a method for the synthesis of certain bridged fused ring pyridines. Such bridged fused ring pyridines can be converted to huperzine A and analogs of huperzine A....
15	5637554	5-substituted 4-methyl-5H-indeno[3,2-b]pyridines and 9-substituted 1-methyl-9H-indeno[2,3-c]pyridines, their preparation and use as herbicides and plant growth regulators A method for controlling undesired plant growth and for regulating plant growth by allowing 4-methyl-5H-indeno[3,2-b]pyridines and 1-methyl-9H-indeno[2,3-c]pyridines of the general formula I...
16	5438056	Heterocyclic oxime carbamates The compounds of the present invention have the following formula: ##STR1## wherein R 1 and R 2 are independently phenyl, pyridyl, thienyl, naphthyl, substituted phenyl wherein the substituent is...
17	5424430	Disubstituted polycyclic systems and preparative methods therefor Polycyclic cognition enhancers having the general formula (1a), (1b) or (1c) are provided: ##STR1## wherein: R 1 is a heterocyclic aromatic moiety such as a 4-pyridyl, 2-pyridyl, 4-pyrimidyl, or...
18	5276053	Polycyclic amines useful as cerebrovascular agents A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of...
19	5254561	Tricyclic antipsychotic agents A class of 2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-c]pyridine and 2,3,4,4a,5,6,7,11b-octahydro-1H-benzo[3,4]cyclohepta[1,2-c]p yridine derivatives are selective ligands at sigma recognition sites and...
20	5248681	Dihydropyridine antiallergy agents
21	5185447	Polycyclic ketones and preparative methods therefor Ketones having formulas (1)-(3) are provided by improved methods which involve the treatment of compounds having formulas (9)-(11) with aqueous base. ##STR1## wherein R x is NO 2 .
22	5162335	Di- and tetrahydroisoquinoline derivatives The invention relates to new di- and tetrahydroisoquinoline derivatives having interesting cytostatic properties, to the preparation of the said new compounds, and to compositions comprising such a...
23	5086179	Process for the preparation of optically pure amides This invention is directed to certain dibenzofurancarboxamides and dibenzofurancarboxamide acids and their use as 5HT 3 antagonists having unique CNS, anti-emetic and gastric prokinetic activity...
24	5071853	Polycyclic amines useful as cerebrovascular agents A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of...
25	5068379	Method for preparing sulfonimidoyl halides N-triorganosilylsulfonimidoyl halides are prepared using a novel series of reactions from compounds of hexavalent sulfur selected from amides, chlorides and anhydrides of organosulfonic acids. More...
26	5030631	Tricylclic arylsulfonamides Novel tricyclic arylsulfonamides useful for treating hypertension and bronchoconstiction, as well as to their pharmaceutical compositions and methods for using the same.
27	4954509	Isoquinoline derivatives and their use as analgesics A compound, or a solvate or salt thereof, of formula (I): ##STR1## in which: RCO is an acyl group in which the group R contains a substituted or unsubstituted carbocyclic aromatic or heterocyclic...
28	4873250	Antimicrobial compound and compositions particulary effective against candida albicans The use of the naturally occurring and readily synthesized alkaloid compound onychine as an antimicrobial agent and particularly against Candida albicans organism.
29	4824852	Substituted indole compounds which have useful effects on the central nervous system New indole derivatives of the general formula I ##STR1## in which Ind is a 3-indolyl radical which can be substituted by a hydroxymethyl, methylenedioxy, S-alkyl, SO-alkyl, SO 2 -alkyl, CN or COW...
30	4808718	Fused polycyclic and bridged compounds useful as calcium channel blockers Novel fused polycyclic and bridged compounds are disclosed which are useful as calcium entry blockers.
31	4778894	6 oxo-decahydroquinolines Tautomeric mixtures of trans-(±)-3,5-dialkyloctahydropyrazolo[3,4-g]quinoline, of trans-(±)-6-alkyloctahydropyrazolo[4,3-f]quinoline, and of...
32	4652567	Benzo(c)-1,5-naphthyridines useful for treating a patient having drug induced memory impairment in need of memory enhancement There are disclosed novel compounds of the formula ##STR1## where X is H, halogen, loweralkyl, loweralkoxy, --CF 3 , or --OH; R is H, loweralkyl, arylloweralkyl, diarylloweralkyl, loweralkanoyl,...
33	4605660	Indeno[2,1-c]pyridine compounds, and their use as calcium channel blockers Indeno[2,1-c]pyridine compounds, particularly cyano substituted tetrahydroindeno[2,1-c]pyridine dicarboxylic acid ester compounds, their preparation and their use as calcium entry blockers are...
34	4593033	Substituted indeno[2,1-c] pyridines useful as calcium channel blockers Novel substituted indeno[2,1-c] pyridine compounds useful as calcium channel blockers, pharmaceutical compositions thereof, and methods of treatment are disclosed.
35	4535085	Perfluorotricyclic amines as oxygen carriers A perfluorotricyclic amine compound which is usable as an oxygen carrier in an artificial blood, represented by the general formula ##STR1## wherein R denotes a perfluoroalkyl group having 1-4...
36	4529798	Process for preparing cyano derivatives of tetrahydroquinolines and related compounds Fused carbocyclic ring derivatives of pyridine which contain a nitrile or thioamide group on the carbocyclic ring e.g. 8-cyano or thiocarboxamido-5,6,7,8-tetrahydroquinolines are prepared by a...
37	4511569	Tricyclic lactams and derivatives useful in increasing cardiac contractility Disclosed are 5,6-dihydro benzo[f]quinolines and derivatives which are effective in increasing cardiac contractility. These compounds are useful in the treatment of congestive heart failure.
38	4487778	Insecticidal esters derived from benzocycloalkane-thiophenemethyl compounds Certain benzocycloalkaneheteroaromaticmethyl, e.g., benzocycloalkanethiophenemethyl, esters and insecticidal compositions containing these esters are useful for the control of a broad range of ...
39	4482714	Pyrazino[2',3'-3,4]pyrido[1,2-a]indole derivatives Herein is disclosed pyrazino[2',3'-3,4]pyrido[1,2-a]indole derivatives, therapeutically acceptable acid addition salts thereof, processes for their preparation, methods of using the derivatives and...
40	4451398	Dyes containing imidazolymethylene groups Dyes of the formula ##STR1## where R 1 is hydrogen, C 1 -C 6 -alkyl or C 2 -C 6 -alkenyl, R 2 and R 3 independently of one another are hydrogen, C 1 -C 5 -alkyl or C 2 -C 5 -alkenyl, R 4...
41	4180666	3 ,9-Dihydro-3,9-dioxo-2H-indeno(2,1-c)-pyridine-4-(carbonitriles/carboxami des) Preparation and use of anticonvulsant 3,9-dihydro-3,9-dioxo-2H-indeno[2,1-c]pyridine-4-(carbonitri les/carboxamid es) are disclosed.
42	4118497	Antidepressantly active 5-(4-aminophenyl)-hexahydro-1H-indeno-(1,2-b)pyridine The invention relates to hexahydro-1H-indeno/1,2-b/pyridines and a process for their manufacture. These compounds and the physiologically tolerable salts thereof are useful as agents for the...
43	4082773	Tricyclic tetrahydro naphthaleneols and related compounds Compounds are provided of the structure ##STR1## WHEREIN X--Z--Y together with two carbons of the cycloalkyl ring form a 5- or 6-membered ring, wherein R 1 is hydrogen, aralkyl or acyl, n is 0, 1...
44	4058529	Polycyclic amino derivatives of pyrrolidone and piperidone A series of compounds of the formula ##STR1## have been found to exhibit useful pharmacological properties, e.g. antiinflammatory and analgetic activity.
45	4022792	Methylidenepiperidines 1,2,3,4,4a,5,10,10a-Octahydro-5-(Y 3 )-5-(Y 4 )-benzo[g]quinolines and 1,2,3,4,4a,9b-hexahydro-5-(Y 3 )-5-(Y 4 )-5H-indeno[1,2,b]pyridi nes wherein Y 3 and Y 4 are hydrogen, alkyl or phenyl,...
46	3991066	1,3,4,9B-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridines The invention concerns novel indenopyridine derivatives of the formula: ##SPC1## Wherein m is 1, 2, 3 or 4, and R 3 is an --O--R 4 group, Wherein R 4 is alkyl of 1 to 5 carbon atoms,...
47	3981875	2-Substituted-9-phenyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-c]pyridines and related compounds 2-Substituted-9-phenyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1 -c]pyridines having anti-arrhythmic activity are described herein. The subject compounds can be prepared by reduction of the...
48	3980656	Partially hydrogenated 1H-indeno-[1,2-b]-pyridine derivatives Partially hydrogenated 1H-indeno[1,2-b]-pyridine derivatives of the general formula I ##SPC1## in which R 1 and R 2 , which may be identical or different, represent hydrogen, halogen or alkoxy...
49	3976653	3-Piperidine-methanols 1,2,3,4,4a,5,10,10a-octahydro-5-(Y 3 )-5-(Y 4 )-benzo[g]quinolines and 1,2,3,4,4a,9b-hexahydro-5-(Y 3 )-5-(Y 4 )-5H-indeno[1,2,b]pyridi nes wherein Y 3 and Y 4 are hydrogen, alkyl or phenyl,...
50	3974167	(7-Nitro-2-aza-9-fluorenylidene) malononitrile Photosensitive material for use in electrophotography which is a charge transfer complex comprising (mononitro-2-aza-9-fluorenylidene) malononitrile and an organic photoconductor.

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